-
1
-
-
0035172428
-
Treatment of recurrent or progressive malignant glioma with a recombinant adenovirus expressing human interferon-beta (H5.010CMVhINF-beta): A phase I trial
-
Eck SL, Alavi JB, Judy K, Phillips P, Alavi A, Hackney D et al. Treatment of recurrent or progressive malignant glioma with a recombinant adenovirus expressing human interferon-beta (H5.010CMVhINF-beta): A phase I trial. Hum Gene Ther 2001; 12: 97-113.
-
(2001)
Hum. Gene Ther
, vol.12
, pp. 97-113
-
-
Eck, S.L.1
Alavi, J.B.2
Judy, K.3
Phillips, P.4
Alavi, A.5
Hackney, D.6
-
2
-
-
0034136802
-
Phase I study of adenoviral delivery of the HSK-tk gene and ganciclovir administration in patients with current malignant brain tumors
-
Trask TW, Trask RP, Aguilar-Cordova F, Shine HD, Wyde PR, Goodman JC et al. Phase I study of adenoviral delivery of the HSK-tk gene and ganciclovir administration in patients with current malignant brain tumors. Mol Ther 2000; 1: 195-203.
-
(2000)
Mol Ther
, vol.1
, pp. 195-203
-
-
Trask, T.W.1
Trask, R.P.2
Aguilar-Cordova, F.3
Shine, H.D.4
Wyde, P.R.5
Goodman, J.C.6
-
3
-
-
0035839562
-
Subthalamic GAD gene transfer in Parkinson's disease patients who are candidates for deep brain stimulation
-
During MJ, Kaplitt MG, Stern MB, Eidelberg D. Subthalamic GAD gene transfer in Parkinson's disease patients who are candidates for deep brain stimulation. Hum Gene Ther 2001; 12: 1589-1591.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 1589-1591
-
-
During, M.J.1
Kaplitt, M.G.2
Stern, M.B.3
Eidelberg, D.4
-
4
-
-
0037143294
-
Clinical protocol. Gene Therapy of Canavan disease: AAV-2 vector for neurosurgical delivery of aspartoacylase gene (ASPA) to the human brain
-
Janson C, McPhee S, Bilaniuk L, Haselgrove J, Testaiuti M, Freese A et al. Clinical protocol. Gene Therapy of Canavan disease: AAV-2 vector for neurosurgical delivery of aspartoacylase gene (ASPA) to the human brain. Hum Gene Ther 2002; 13: 1391-1412.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1391-1412
-
-
Janson, C.1
McPhee, S.2
Bilaniuk, L.3
Haselgrove, J.4
Testaiuti, M.5
Freese, A.6
-
5
-
-
0034882629
-
Parkinson's disease: Etiology, pathogenesis and future of gene therapy
-
Shastry BS. Parkinson's disease: Etiology, pathogenesis and future of gene therapy. Neurosci Res 2001; 41: 5-12.
-
(2001)
Neurosci Res
, vol.41
, pp. 5-12
-
-
Shastry, B.S.1
-
7
-
-
0042809823
-
Neuroprotection in Parkinson disease
-
Simpkinsn N, Jankovic J. Neuroprotection in Parkinson disease. Arch Intern Med 2003; 163: 1650-1654.
-
(2003)
Arch Intern Med
, vol.163
, pp. 1650-1654
-
-
Simpkinsn, N.1
Jankovic, J.2
-
8
-
-
0034758936
-
Prospects for the treatment of Parkinson's disease using neurotrophic factor
-
Hurelbrink CB, Barker RA. Prospects for the treatment of Parkinson's disease using neurotrophic factor. Expert Opin Pharmacother 2001; 2: 1531-1543.
-
(2001)
Expert Opin Pharmacother
, vol.2
, pp. 1531-1543
-
-
Hurelbrink, C.B.1
Barker, R.A.2
-
9
-
-
85047698430
-
Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease
-
Wang L, Muramatsu S, Lu Y, Ikeguchi K, Fujimoto K, Okada T et al. Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease. Gene Therapy 2002; 9: 381-399.
-
(2002)
Gene Therapy
, vol.9
, pp. 381-399
-
-
Wang, L.1
Muramatsu, S.2
Lu, Y.3
Ikeguchi, K.4
Fujimoto, K.5
Okada, T.6
-
10
-
-
0343517507
-
Lentiviral vectors as a gene delivery system in the mouse midbrain: Cellular and behavioral improvements in a 6-OHDA model of Parkinson's disease using GDNF
-
Bensadoun JC, Deglon N, Tseng JL, Ridet JL, Zurn AD, Aebischer P. Lentiviral vectors as a gene delivery system in the mouse midbrain: cellular and behavioral improvements in a 6-OHDA model of Parkinson's disease using GDNF. Exp Neurol 2000; 164: 15-24.
-
(2000)
Exp Neurol
, vol.164
, pp. 15-24
-
-
Bensadoun, J.C.1
Deglon, N.2
Tseng, J.L.3
Ridet, J.L.4
Zurn, A.D.5
Aebischer, P.6
-
11
-
-
20044390031
-
The differences between high and low-dose administration of VEGF to dopaminergic neurons of in vitro and in vivo Parkinson's disease model
-
Yasuhara T, Shingo T, Muraoka K, Wen Ji Y, Kameda M, Takeuchi A et al. The differences between high and low-dose administration of VEGF to dopaminergic neurons of in vitro and in vivo Parkinson's disease model. Brain Res 2005; 1038: 1-10.
-
(2005)
Brain Res
, vol.1038
, pp. 1-10
-
-
Yasuhara, T.1
Shingo, T.2
Muraoka, K.3
Wen Ji, Y.4
Kameda, M.5
Takeuchi, A.6
-
12
-
-
0024427178
-
Molecular cloning and expression of human hepatocyte growth factor
-
Nakamura T, Nishizawa T, Hagiya M, Seki T, Shimonishi M, Sugimura A et al. Molecular cloning and expression of human hepatocyte growth factor. Nature 1989; 342: 440-443.
-
(1989)
Nature
, vol.342
, pp. 440-443
-
-
Nakamura, T.1
Nishizawa, T.2
Hagiya, M.3
Seki, T.4
Shimonishi, M.5
Sugimura, A.6
-
13
-
-
0036703771
-
Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS
-
Sun W, Funakoshi H, Nakamura T. Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS. J Neurosci 2002; 22: 6537-6548.
-
(2002)
J Neurosci
, vol.22
, pp. 6537-6548
-
-
Sun, W.1
Funakoshi, H.2
Nakamura, T.3
-
14
-
-
0000135127
-
Protection of hippocampal neurons from ischemia-induced delayed neuronal death by hepatocyte growth factor: A novel neurotrophic factor
-
Miyazawa T, Matsumoto K, Ohmichi H, Yamashima T, Chigasaki H, Nakamura T. Protection of hippocampal neurons from ischemia-induced delayed neuronal death by hepatocyte growth factor: A novel neurotrophic factor. J Celebral Blood Flow Metab 1998; 18: 345-348.
-
(1998)
J Celebral Blood Flow Metab
, vol.18
, pp. 345-348
-
-
Miyazawa, T.1
Matsumoto, K.2
Ohmichi, H.3
Yamashima, T.4
Chigasaki, H.5
Nakamura, T.6
-
15
-
-
8444246829
-
Hepatocyte growth factor improved learning and memory dysfunction of microsphene embolized rats
-
Date I, Takagi N, Takagi K, Kago T, Matsumoto K, Nakamura T et al. Hepatocyte growth factor improved learning and memory dysfunction of microsphene embolized rats. J Neurosci Res 2004; 78: 442-453.
-
(2004)
J Neurosci Res
, vol.78
, pp. 442-453
-
-
Date, I.1
Takagi, N.2
Takagi, K.3
Kago, T.4
Matsumoto, K.5
Nakamura, T.6
-
16
-
-
0029912944
-
Neurotrophic effect of hepatocyte growth factor on central nervous system neurons in vitro
-
Hamanoue M, Takemoto N, Matsumoto K, Nakamura T, Nakajima K, Kohsaka S. Neurotrophic effect of hepatocyte growth factor on central nervous system neurons in vitro. J Neurosci Res 1996; 43: 554-564.
-
(1996)
J Neurosci Res
, vol.43
, pp. 554-564
-
-
Hamanoue, M.1
Takemoto, N.2
Matsumoto, K.3
Nakamura, T.4
Nakajima, K.5
Kohsaka, S.6
-
17
-
-
0037387794
-
Enhanced angiogenesis and improvement of neuropathy by cotransfection of human hepatocyte growth factor and prostacyclin synthase gene
-
Koike H, Morishita R, Iguchi S, Aoki M, Matsumoto K, Nakamura T et al. Enhanced angiogenesis and improvement of neuropathy by cotransfection of human hepatocyte growth factor and prostacyclin synthase gene. FASEB J 2003; 17: 779-781.
-
(2003)
FASEB J
, vol.17
, pp. 779-781
-
-
Koike, H.1
Morishita, R.2
Iguchi, S.3
Aoki, M.4
Matsumoto, K.5
Nakamura, T.6
-
18
-
-
0037453059
-
Angiogenic property of hepatocyte growth factor is dependent on upregulation of essential transcription factor for angiogenesis, ets-1
-
Tomita N, Morishita R, Taniyama Y, Koike H, Aoki M, Shimizu H et al. Angiogenic property of hepatocyte growth factor is dependent on upregulation of essential transcription factor for angiogenesis, ets-1. Circulation 2003; 107: 1411-1417.
-
(2003)
Circulation
, vol.107
, pp. 1411-1417
-
-
Tomita, N.1
Morishita, R.2
Taniyama, Y.3
Koike, H.4
Aoki, M.5
Shimizu, H.6
-
19
-
-
0036896566
-
Recent progress in gene therapy for cardiovascular disease
-
Morishita R. Recent progress in gene therapy for cardiovascular disease. Circ J 2002; 66: 1077-1086.
-
(2002)
Circ J
, vol.66
, pp. 1077-1086
-
-
Morishita, R.1
-
20
-
-
0033362351
-
Hepatocyte growth factor, a versatile signal for developing neurons
-
Maina F, Klein R. Hepatocyte growth factor, a versatile signal for developing neurons. Nat Neurosci 1999; 2: 213-217.
-
(1999)
Nat Neurosci
, vol.2
, pp. 213-217
-
-
Maina, F.1
Klein, R.2
-
21
-
-
17844393413
-
Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors
-
Schnell MA, Zhang Y, Tazelaar J, Gao GP, Yu QC, Qian R et al. Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors. Mol Ther 2001; 3: 708-722.
-
(2001)
Mol Ther
, vol.3
, pp. 708-722
-
-
Schnell, M.A.1
Zhang, Y.2
Tazelaar, J.3
Gao, G.P.4
Yu, Q.C.5
Qian, R.6
-
22
-
-
0032741719
-
Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: Implication for clinical trial
-
Dewey RA, Morrissey G, Cowsill CM, Stone D, Bolognani F, Dodd NJ et al. Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: Implication for clinical trial. Nat Med 1999; 5: 1256-1263.
-
(1999)
Nat Med
, vol.5
, pp. 1256-1263
-
-
Dewey, R.A.1
Morrissey, G.2
Cowsill, C.M.3
Stone, D.4
Bolognani, F.5
Dodd, N.J.6
-
23
-
-
0036202298
-
Critical issues in gene therapy for neurologic disease
-
Hsich G, Sena-Esteves M, Breakfield XO. Critical issues in gene therapy for neurologic disease. Hum Gene Ther 2002; 13: 579-604.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 579-604
-
-
Hsich, G.1
Sena-Esteves, M.2
Breakfield, X.O.3
-
24
-
-
0038249170
-
Direct brain of glial cell line-derived neurotrophic factor in Parkinson disease
-
Gill SS, Patel NK, Hotton GR, O'Sullivan K, McCarter R, Bunnage M et al. Direct brain of glial cell line-derived neurotrophic factor in Parkinson disease. Nat Med 2003; 9: 589-595.
-
(2003)
Nat Med
, vol.9
, pp. 589-595
-
-
Gill, S.S.1
Patel, N.K.2
Hotton, G.R.3
O'Sullivan, K.4
McCarter, R.5
Bunnage, M.6
-
25
-
-
0029142780
-
Localization and functional coupling of HGF and c-Met/HGF receptor in rat brain: Implication as neurotrophic factor
-
Honda S, Kagoshima M, Wanaka A, Tohyama M, Matsumoto K, Nakamura T. Localization and functional coupling of HGF and c-Met/HGF receptor in rat brain: Implication as neurotrophic factor. Mol Brain Res 1995; 32: 197-210.
-
(1995)
Mol. Brain Res
, vol.32
, pp. 197-210
-
-
Honda, S.1
Kagoshima, M.2
Wanaka, A.3
Tohyama, M.4
Matsumoto, K.5
Nakamura, T.6
-
26
-
-
0034651876
-
Hepatocyte growth factor protects cultured rat cerebellar granule neurons from apoptosis via the phosphatidylinositol-3 kinase/Akt pathway
-
Zhang L, Himi T, Morita I, Murota S. Hepatocyte growth factor protects cultured rat cerebellar granule neurons from apoptosis via the phosphatidylinositol-3 kinase/Akt pathway. J Neurosci Res 2000; 59: 489-496.
-
(2000)
J Neurosci Res
, vol.59
, pp. 489-496
-
-
Zhang, L.1
Himi, T.2
Morita, I.3
Murota, S.4
-
27
-
-
0033951972
-
Cooperation between HGF and CNTF in promoting the survival and growth of sensory and parasympathetic neurons
-
Davey F, Hilton M, Davies AM. Cooperation between HGF and CNTF in promoting the survival and growth of sensory and parasympathetic neurons. Mol Cell Neurosci 2000; 15: 79-87.
-
(2000)
Mol Cell Neurosci
, vol.15
, pp. 79-87
-
-
Davey, F.1
Hilton, M.2
Davies, A.M.3
-
28
-
-
17944375146
-
Gene therapy for preventing neuronal death using hepatocyte growth factor: In vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons
-
Hayashi K, Morishita R, Nakagami H, Yoshimura S, Hara A, Matsumoto K et al. Gene therapy for preventing neuronal death using hepatocyte growth factor: In vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons. Gene Therapy 2001; 8: 1167-1173.
-
(2001)
Gene Therapy
, vol.8
, pp. 1167-1173
-
-
Hayashi, K.1
Morishita, R.2
Nakagami, H.3
Yoshimura, S.4
Hara, A.5
Matsumoto, K.6
-
29
-
-
0034612203
-
Lower-extremity edema associated with gene transfer of naked DNA encoding vascular endothelial growth factor
-
Baumgartner I, Rauh G, Pieczek A, Wuensch D, Magner M, Kearney M et al. Lower-extremity edema associated with gene transfer of naked DNA encoding vascular endothelial growth factor. Ann Intern Med 2000; 132: 880-884.
-
(2000)
Ann Intern Med
, vol.132
, pp. 880-884
-
-
Baumgartner, I.1
Rauh, G.2
Pieczek, A.3
Wuensch, D.4
Magner, M.5
Kearney, M.6
-
30
-
-
0034730094
-
Left ventricular electromechanical mapping to assess efficacy of phVEGF165 gene transfer for therapeutic angiogenesis in chronic myocardial ischemia
-
Vale PR, Losordo DW, Milliken CE, Maysky M, Esakof DD, Symes JF et al. Left ventricular electromechanical mapping to assess efficacy of phVEGF165 gene transfer for therapeutic angiogenesis in chronic myocardial ischemia. Circulation 2000; 102: 965-974.
-
(2000)
Circulation
, vol.102
, pp. 965-974
-
-
Vale, P.R.1
Losordo, D.W.2
Milliken, C.E.3
Maysky, M.4
Esakof, D.D.5
Symes, J.F.6
-
31
-
-
3543025721
-
Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease by therapeutic angiogenesis
-
Morishita R, Aoki M, Hashiya N, Makino H, Yamasaki K, Azuma J et al. Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease by therapeutic angiogenesis. Hypertension 2004; 44: 203-209.
-
(2004)
Hypertension
, vol.44
, pp. 203-209
-
-
Morishita, R.1
Aoki, M.2
Hashiya, N.3
Makino, H.4
Yamasaki, K.5
Azuma, J.6
-
32
-
-
0029998364
-
Gene transfer by naked DNA into adult mouse brain
-
Schwartz B, Benoist C, Abdallah B, Rangara R, Hassan A, Scherman D et al. Gene transfer by naked DNA into adult mouse brain. Gene Therapy 1996; 3: 405-411.
-
(1996)
Gene Therapy
, vol.3
, pp. 405-411
-
-
Schwartz, B.1
Benoist, C.2
Abdallah, B.3
Rangara, R.4
Hassan, A.5
Scherman, D.6
-
33
-
-
0037306049
-
Exogenous expression of hepatocyte growth factor (HGF) in rat striatum by naked fplasmid DNA
-
Sekiguchi K, Yasuzumi F, Morishita R. Exogenous expression of hepatocyte growth factor (HGF) in rat striatum by naked fplasmid DNA. Neurosci Res 2003; 45: 173-180.
-
(2003)
Neurosci Res
, vol.45
, pp. 173-180
-
-
Sekiguchi, K.1
Yasuzumi, F.2
Morishita, R.3
|