Acute hepatocyte growth factor treatment induces long-term neuroprotection and stroke recovery via mechanisms involving neural precursor cell proliferation and differentiation

Journal of Cerebral Blood Flow and Metabolism

Volumn 31, Issue 5, 2011, Pages 1251-1262

  Doeppner, Thorsten R ^a,d   Kaltwasser, Britta ^a   Elali, Ayman ^b   Zechariah, Anil ^b   Hermann, Dirk M ^b   Bähr, Mathias ^a,c  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b UNIVERSITY OF ESSEN MEDICAL SCHOOL   (Germany)

^c Deutsche Forschungsgemeinschaft   (Germany)

^d UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

cerebral ischemia; hepatocyte growth factor; matrix metalloproteases; neural precursor cells; neurogenesis; stroke

Indexed keywords

CASPASE 3; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE 17; SCATTER FACTOR; NEUROPROTECTIVE AGENT;

ANALYTICAL PARAMETERS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN HYPOXIA; BRAIN INFARCTION; BRAIN INJURY; CELL PROLIFERATION; CONTROLLED STUDY; CORNER TURN TEST; CORPUS STRIATUM; DISEASE ASSOCIATION; DRUG INHIBITION; IN VITRO STUDY; MALE; MOUSE; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE CELL NECROSIS; NEURAL PRECURSOR CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; STROKE; TIGHT ROPE TEST; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; CONVALESCENCE; CYTOLOGY; DRUG EFFECT; IMMUNOHISTOCHEMISTRY; NEURAL STEM CELL; NICK END LABELING; PATHOLOGY; TIME;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; HEPATOCYTE GROWTH FACTOR; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MALE; MICE; MICE, INBRED C57BL; NEURAL STEM CELLS; NEUROPROTECTIVE AGENTS; RECOVERY OF FUNCTION; STROKE; TIME;

EID: 79959678293     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2010.211     Document Type: Article

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