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Volumn 7, Issue 12, 2014, Pages 8342-8355

Neuroinflammation in Alzheimer's disease: Chemokines produced by astrocytes and chemokine receptors

Author keywords

Alzheimer's disease; Astrocytes; Chemokine receptors; Chemokines; Inflammation

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR;

EID: 84921521862     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (166)

References (123)
  • 3
    • 4944258716 scopus 로고    scopus 로고
    • The role of inflammation in Alzheimer's disease
    • Tuppo EE and Arias HR. The role of inflammation in Alzheimer's disease. Int J Biochem Cell Biol 2005; 37: 289-305.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 289-305
    • Tuppo, E.E.1    Arias, H.R.2
  • 5
    • 0033983516 scopus 로고    scopus 로고
    • Microglia and astrocytes in the adult rat brain: comparative immunocytochemical analysis demonstrates the efficacy of lipocortin 1 immunoreactivity
    • Savchenko VL, McKanna JA, Nikonenko IR and Skibo GG. Microglia and astrocytes in the adult rat brain: comparative immunocytochemical analysis demonstrates the efficacy of lipocortin 1 immunoreactivity. Neuroscience 2000; 96: 195-203.
    • (2000) Neuroscience , vol.96 , pp. 195-203
    • Savchenko, V.L.1    McKanna, J.A.2    Nikonenko, I.R.3    Skibo, G.G.4
  • 6
    • 13844281550 scopus 로고    scopus 로고
    • How chronic inflammation can affect the brain and support the development of Alzheimer's disease in old age: the role of microglia and astrocytes
    • Blasko I, Stampfer-Kountchev M, Robatscher P, Veerhuis R, Eikelenboom P and Grubeck-Loebenstein B. How chronic inflammation can affect the brain and support the development of Alzheimer's disease in old age: the role of microglia and astrocytes. Aging Cell 2004; 3: 169-176.
    • (2004) Aging Cell , vol.3 , pp. 169-176
    • Blasko, I.1    Stampfer-Kountchev, M.2    Robatscher, P.3    Veerhuis, R.4    Eikelenboom, P.5    Grubeck-Loebenstein, B.6
  • 9
    • 0036948724 scopus 로고    scopus 로고
    • Neural immunity: Friend or foe?
    • Gendelman HE. Neural immunity: Friend or foe? J Neurovirol 2002; 8: 474-479.
    • (2002) J Neurovirol , vol.8 , pp. 474-479
    • Gendelman, H.E.1
  • 11
    • 0031927636 scopus 로고    scopus 로고
    • Confocal observation of senile plaques in Alzheimer's disease: senile plaque morphology and relationship between senile plaques and astrocytes
    • Kato S, Gondo T, Hoshii Y, Takahashi M, Yamada M and Ishihara T. Confocal observation of senile plaques in Alzheimer's disease: senile plaque morphology and relationship between senile plaques and astrocytes. Pathol Int 1998; 48: 332-340.
    • (1998) Pathol Int , vol.48 , pp. 332-340
    • Kato, S.1    Gondo, T.2    Hoshii, Y.3    Takahashi, M.4    Yamada, M.5    Ishihara, T.6
  • 13
    • 0034523456 scopus 로고    scopus 로고
    • Costimulatory effects of interferon-Γ and interleukin-1β or tumor necrosis factor a on the synthesis of Aβ1-40 and Aβ1-42 by human astrocytes.
    • Blasko I, Veerhuis R, Stampfer-Kountchev M, Saurwein-Teissl M, Eikelenboom P and Grubeck-Loebenstein B. Costimulatory effects of interferon-Γ and interleukin-1β or tumor necrosis factor a on the synthesis of Aβ1-40 and Aβ1-42 by human astrocytes. Neurobiol Dis 2000; 7: 682-689.
    • (2000) Neurobiol Dis , vol.7 , pp. 682-689
    • Blasko, I.1    Veerhuis, R.2    Stampfer-Kountchev, M.3    Saurwein-Teissl, M.4    Eikelenboom, P.5    Grubeck-Loebenstein, B.6
  • 15
    • 37349114621 scopus 로고    scopus 로고
    • Transplanted astrocytes internalize deposited β-amyloid peptides in a transgenic mouse model of Alzheimer's disease
    • Pihlaja R, Koistinaho J, Malm T, Sikkilä H, Vainio S and Koistinaho M. Transplanted astrocytes internalize deposited β-amyloid peptides in a transgenic mouse model of Alzheimer's disease. Glia 2008; 56: 154-163.
    • (2008) Glia , vol.56 , pp. 154-163
    • Pihlaja, R.1    Koistinaho, J.2    Malm, T.3    Sikkilä, H.4    Vainio, S.5    Koistinaho, M.6
  • 16
    • 0031258670 scopus 로고    scopus 로고
    • β-amyloid fragment potentiates IL-6 and TNF-α secretion by LPS in astrocytes but not in microglia
    • Forloni G, Mangiarotti F, Angeretti N, Lucca E and De Simoni MG. β-amyloid fragment potentiates IL-6 and TNF-α secretion by LPS in astrocytes but not in microglia. Cytokine 1997; 9: 759-762.
    • (1997) Cytokine , vol.9 , pp. 759-762
    • Forloni, G.1    Mangiarotti, F.2    Angeretti, N.3    Lucca, E.4    De Simoni, M.G.5
  • 17
    • 0036959504 scopus 로고    scopus 로고
    • Regulation of promoter activity of the APP gene by cytokines and growth factors
    • GE YW and Lahiri D. Regulation of promoter activity of the APP gene by cytokines and growth factors. Ann N Y Acad Sci 2002; 973: 463-467.
    • (2002) Ann N Y Acad Sci , vol.973 , pp. 463-467
    • G.E, Y.W.1    Lahiri, D.2
  • 18
    • 25644456097 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease
    • Kitazawa M, Oddo S, Yamasaki TR, Green KN and LaFerla FM. Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease. J Neurosci 2005; 25: 8843-8853.
    • (2005) J Neurosci , vol.25 , pp. 8843-8853
    • Kitazawa, M.1    Oddo, S.2    Yamasaki, T.R.3    Green, K.N.4    LaFerla, F.M.5
  • 19
    • 33744968899 scopus 로고    scopus 로고
    • Signals for the induction of nitric oxide synthase in astrocytes
    • Saha RN and Pahan K. Signals for the induction of nitric oxide synthase in astrocytes. Neurochem Int 2006; 49: 154-163.
    • (2006) Neurochem Int , vol.49 , pp. 154-163
    • Saha, R.N.1    Pahan, K.2
  • 22
    • 0034080318 scopus 로고    scopus 로고
    • The biology of chemokines and their receptors
    • Rossi D and Zlotnik A. The biology of chemokines and their receptors. Ann Rev Immunol 2000; 18: 217-242.
    • (2000) Ann Rev Immunol , vol.18 , pp. 217-242
    • Rossi, D.1    Zlotnik, A.2
  • 23
    • 84884246344 scopus 로고    scopus 로고
    • Cytokines and chemokines at the crossroads of neuroinflammation, neurodegeneration, and neuropathic pain
    • Ramesh G, MacLean AG and Philipp MT. Cytokines and chemokines at the crossroads of neuroinflammation, neurodegeneration, and neuropathic pain. Mediators Inflamm 2013; 2013: 20.
    • (2013) Mediators Inflamm , vol.2013 , pp. 20
    • Ramesh, G.1    MacLean, A.G.2    Philipp, M.T.3
  • 24
    • 0032892888 scopus 로고    scopus 로고
    • Chemokine and chemokine receptor expression in the central nervous system
    • Hesselgesser J and Horuk R. Chemokine and chemokine receptor expression in the central nervous system. J Neurovirol 1999; 5: 13-26.
    • (1999) J Neurovirol , vol.5 , pp. 13-26
    • Hesselgesser, J.1    Horuk, R.2
  • 27
    • 77955919746 scopus 로고    scopus 로고
    • Biomarkers in translational research of Alzheimer's disease
    • Tarawneh R and Holtzman DM. Biomarkers in translational research of Alzheimer's disease. Neuropharmacology 2010; 59: 310-322.
    • (2010) Neuropharmacology , vol.59 , pp. 310-322
    • Tarawneh, R.1    Holtzman, D.M.2
  • 28
    • 84856383137 scopus 로고    scopus 로고
    • CCL2 is associated with a faster rate of cognitive decline during early stages of Alzheimer's disease
    • Westin K, Buchhave P, Nielsen H, Minthon L, Janciauskiene S and Hansson O. CCL2 is associated with a faster rate of cognitive decline during early stages of Alzheimer's disease. PLoS One 2012; 7: e30525.
    • (2012) PLoS One , vol.7
    • Westin, K.1    Buchhave, P.2    Nielsen, H.3    Minthon, L.4    Janciauskiene, S.5    Hansson, O.6
  • 32
    • 41949125406 scopus 로고    scopus 로고
    • Changes in the levels of plasma soluble fractalkine in patients with mild cognitive impairment and Alzheimer's disease
    • Kim TS, Lim HK, Lee JY, Kim DJ, Park S, Lee C and Lee CU. Changes in the levels of plasma soluble fractalkine in patients with mild cognitive impairment and Alzheimer's disease. Neurosci Lett 2008; 436: 196-200.
    • (2008) Neurosci Lett , vol.436 , pp. 196-200
    • Kim, T.S.1    Lim, H.K.2    Lee, J.Y.3    Kim, D.J.4    Park, S.5    Lee, C.6    Lee, C.U.7
  • 35
    • 60749091489 scopus 로고    scopus 로고
    • Interaction between interleukin-8 and methylenetetrahydrofolate reductase genes modulates Alzheimer's disease risk
    • Li K, Liu S, Yao S, Wang B, Dai D and Yao L. Interaction between interleukin-8 and methylenetetrahydrofolate reductase genes modulates Alzheimer's disease risk. Dement Geriatr Cogn Disord 2009; 27: 286-291.
    • (2009) Dement Geriatr Cogn Disord , vol.27 , pp. 286-291
    • Li, K.1    Liu, S.2    Yao, S.3    Wang, B.4    Dai, D.5    Yao, L.6
  • 39
    • 80053467576 scopus 로고    scopus 로고
    • [Changes of nuclear factor and inflammatory chemotactic factors in brain of patients with Alzheimer's disease]
    • Liao Y, Guan ZZ and Ravid R. [Changes of nuclear factor and inflammatory chemotactic factors in brain of patients with Alzheimer's disease]. Zhonghua Bing Li Xue Za Zhi 2011; 40: 585-589.
    • (2011) Zhonghua Bing Li Xue Za Zhi , vol.40 , pp. 585-589
    • Liao, Y.1    Guan, Z.Z.2    Ravid, R.3
  • 40
    • 66949146836 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 plays a dominant role in the chronic inflammation observed in Alzheimer's disease
    • Sokolova A, Hill MD, Rahimi F, Warden LA, Halliday GM and Shepherd CE. Monocyte chemoattractant protein-1 plays a dominant role in the chronic inflammation observed in Alzheimer's disease. Brain Pathol 2009; 19: 392-398.
    • (2009) Brain Pathol , vol.19 , pp. 392-398
    • Sokolova, A.1    Hill, M.D.2    Rahimi, F.3    Warden, L.A.4    Halliday, G.M.5    Shepherd, C.E.6
  • 41
    • 70449529890 scopus 로고    scopus 로고
    • RANTES upregulation in the Alzheimer's disease brain: A possible neuroprotective role
    • Tripathy D, Thirumangalakudi L and Grammas P. RANTES upregulation in the Alzheimer's disease brain: A possible neuroprotective role. Neurobiol Aging 2010; 31: 8-16.
    • (2010) Neurobiol Aging , vol.31 , pp. 8-16
    • Tripathy, D.1    Thirumangalakudi, L.2    Grammas, P.3
  • 43
    • 0034839338 scopus 로고    scopus 로고
    • The chemokine interleukin-8 acutely reduces Ca(2+) currents in identified cholinergic septal neurons expressing CXCR1 and CXCR2 receptor mRNAs
    • Puma C, Danik M, Quirion R, Ramon F and Williams S. The chemokine interleukin-8 acutely reduces Ca(2+) currents in identified cholinergic septal neurons expressing CXCR1 and CXCR2 receptor mRNAs. J Neurochem 2001; 78: 960-971.
    • (2001) J Neurochem , vol.78 , pp. 960-971
    • Puma, C.1    Danik, M.2    Quirion, R.3    Ramon, F.4    Williams, S.5
  • 46
    • 0030951449 scopus 로고    scopus 로고
    • Interleukin-8 receptor B immunoreactivity in brain and neuritic plaques of Alzheimer's disease
    • Xia M, Qin S, McNamara M, Mackay C and Hyman BT. Interleukin-8 receptor B immunoreactivity in brain and neuritic plaques of Alzheimer's disease. Am J Pathol 1997; 150: 1267-1274.
    • (1997) Am J Pathol , vol.150 , pp. 1267-1274
    • Xia, M.1    Qin, S.2    McNamara, M.3    Mackay, C.4    Hyman, B.T.5
  • 47
    • 0037334295 scopus 로고    scopus 로고
    • Regulation of chemokine receptor expression in human microglia and astrocytes
    • Flynn G, Maru S, Loughlin J, Romero IA and Male D. Regulation of chemokine receptor expression in human microglia and astrocytes. J Neuroimmunol 2003; 136: 84-93.
    • (2003) J Neuroimmunol , vol.136 , pp. 84-93
    • Flynn, G.1    Maru, S.2    Loughlin, J.3    Romero, I.A.4    Male, D.5
  • 50
    • 0027530096 scopus 로고
    • Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis
    • Ransohoff R, Hamilton T, Tani M, Stoler M, Shick H, Major J, Estes M, Thomas D and Tuohy V. Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis. FASEB J 1993; 7: 592-600.
    • (1993) FASEB J , vol.7 , pp. 592-600
    • Ransohoff, R.1    Hamilton, T.2    Tani, M.3    Stoler, M.4    Shick, H.5    Major, J.6    Estes, M.7    Thomas, D.8    Tuohy, V.9
  • 51
    • 0034954177 scopus 로고    scopus 로고
    • Interferon-independent, human immunodeficiency virus type 1 gp120-mediated induction of CXCL10/IP-10 gene expression by astrocytes in vivo and in vitro
    • Asensio VC, Maier J, Milner R, Boztug K, Kincaid C, Moulard M, Phillipson C, Lindsley K, Krucker T and Fox HS. Interferon-independent, human immunodeficiency virus type 1 gp120-mediated induction of CXCL10/IP-10 gene expression by astrocytes in vivo and in vitro. J Virol 2001; 75: 7067-7077.
    • (2001) J Virol , vol.75 , pp. 7067-7077
    • Asensio, V.C.1    Maier, J.2    Milner, R.3    Boztug, K.4    Kincaid, C.5    Moulard, M.6    Phillipson, C.7    Lindsley, K.8    Krucker, T.9    Fox, H.S.10
  • 53
    • 0032750459 scopus 로고    scopus 로고
    • Glial and neuronal cells express functional chemokine receptor CXCR4 and its natural ligand stromal cell-derived factor 1
    • Bajetto A, Bonavia R, Barbero S, Piccioli P, Costa A, Florio T and Schettini G. Glial and neuronal cells express functional chemokine receptor CXCR4 and its natural ligand stromal cell-derived factor 1. J Neurochem 1999; 73: 2348-2357.
    • (1999) J Neurochem , vol.73 , pp. 2348-2357
    • Bajetto, A.1    Bonavia, R.2    Barbero, S.3    Piccioli, P.4    Costa, A.5    Florio, T.6    Schettini, G.7
  • 57
    • 0032889037 scopus 로고    scopus 로고
    • Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates
    • Albright AV, Shieh JT, Itoh T, Lee B, Pleasure D, O'Connor MJ, Doms RW and González-Scarano F. Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates. J virol 1999; 73: 205-213.
    • (1999) J virol , vol.73 , pp. 205-213
    • Albright, A.V.1    Shieh, J.T.2    Itoh, T.3    Lee, B.4    Pleasure, D.5    O'Connor, M.J.6    Doms, R.W.7    González-Scarano, F.8
  • 58
    • 3142777716 scopus 로고    scopus 로고
    • Regulation of RANTES/CCL5 expression in human astrocytes by interleukin-1 and interferon-beta
    • Kim MO, Suh HS, Brosnan CF and Lee SC. Regulation of RANTES/CCL5 expression in human astrocytes by interleukin-1 and interferon-beta. J Neurochem 2004; 90: 297-308.
    • (2004) J Neurochem , vol.90 , pp. 297-308
    • Kim, M.O.1    Suh, H.S.2    Brosnan, C.F.3    Lee, S.C.4
  • 60
    • 0031010175 scopus 로고    scopus 로고
    • Monocyte chemotactic protein-2 (MCP-2) uses CCR1 and CCR2B as its functional receptors
    • Gong X, Gong W, Kuhns DB, Ben-Baruch A, Howard OZ and Wang JM. Monocyte chemotactic protein-2 (MCP-2) uses CCR1 and CCR2B as its functional receptors. J Biol Chem 1997; 272: 11682-11685.
    • (1997) J Biol Chem , vol.272 , pp. 11682-11685
    • Gong, X.1    Gong, W.2    Kuhns, D.B.3    Ben-Baruch, A.4    Howard, O.Z.5    Wang, J.M.6
  • 62
    • 79960027354 scopus 로고    scopus 로고
    • MCP-3/CCL7 production by astrocytes: implications for SIV neuroinvasion and AIDS encephalitis
    • Renner NA, Ivey NS, Redmann RK, Lackner AA and MacLean AG. MCP-3/CCL7 production by astrocytes: implications for SIV neuroinvasion and AIDS encephalitis. J Neurovirol 2011; 17: 146-152.
    • (2011) J Neurovirol , vol.17 , pp. 146-152
    • Renner, N.A.1    Ivey, N.S.2    Redmann, R.K.3    Lackner, A.A.4    MacLean, A.G.5
  • 63
    • 0033636254 scopus 로고    scopus 로고
    • Intracerebral recruitment and maturation of dendritic cells in the onset and progression of experimental autoimmune encephalomyelitis
    • Serafini B, Columba-Cabezas S, Di Rosa F and Aloisi F. Intracerebral recruitment and maturation of dendritic cells in the onset and progression of experimental autoimmune encephalomyelitis. Am J Pathol 2000; 157: 1991-2002.
    • (2000) Am J Pathol , vol.157 , pp. 1991-2002
    • Serafini, B.1    Columba-Cabezas, S.2    Di Rosa, F.3    Aloisi, F.4
  • 64
    • 0037327907 scopus 로고    scopus 로고
    • Astrocytes are the major intracerebral source of macrophage inflammatory protein-3a/CCL20 in relapsing experimental autoimmune encephalomyelitis and in vitro
    • Ambrosini E, Columba-Cabezas S, Serafini B, Muscella A and Aloisi F. Astrocytes are the major intracerebral source of macrophage inflammatory protein-3a/CCL20 in relapsing experimental autoimmune encephalomyelitis and in vitro. Glia 2003; 41: 290-300.
    • (2003) Glia , vol.41 , pp. 290-300
    • Ambrosini, E.1    Columba-Cabezas, S.2    Serafini, B.3    Muscella, A.4    Aloisi, F.5
  • 67
    • 0032473596 scopus 로고    scopus 로고
    • Amyloid-β peptide activates cultured astrocytes: morphological alterations, cytokine induction and nitric oxide release
    • Hu J, Akama KT, Krafft GA, Chromy BA and Van Eldik LJ. Amyloid-β peptide activates cultured astrocytes: morphological alterations, cytokine induction and nitric oxide release. Br Res 1998; 785: 195-206.
    • (1998) Br Res , vol.785 , pp. 195-206
    • Hu, J.1    Akama, K.T.2    Krafft, G.A.3    Chromy, B.A.4    Van Eldik, L.J.5
  • 68
    • 0034866550 scopus 로고    scopus 로고
    • Microglia: activation and their significance in the central nervous system
    • Nakajima K and Kohsaka S. Microglia: activation and their significance in the central nervous system. J Biochem 2001; 130: 169-175.
    • (2001) J Biochem , vol.130 , pp. 169-175
    • Nakajima, K.1    Kohsaka, S.2
  • 69
    • 0032460149 scopus 로고    scopus 로고
    • Interfering with the pathologic activation of microglial cells and astrocytes in dementia
    • Schubert P and Rudolphi K. Interfering with the pathologic activation of microglial cells and astrocytes in dementia. Alzheimer Dis Assoc Disord 1998; 12 Suppl 2: S21-28.
    • (1998) Alzheimer Dis Assoc Disord , vol.12 , pp. S21-S28
    • Schubert, P.1    Rudolphi, K.2
  • 71
    • 0032487625 scopus 로고    scopus 로고
    • Alzheimer's β-amyloid peptides induce inflammatory cascade in human vascular cells: the roles of cytokines and CD40
    • Suo Z, Tan J, Placzek A, Crawford F, Fang C and Mullan M. Alzheimer's β-amyloid peptides induce inflammatory cascade in human vascular cells: the roles of cytokines and CD40. Br Res 1998; 807: 110-117.
    • (1998) Br Res , vol.807 , pp. 110-117
    • Suo, Z.1    Tan, J.2    Placzek, A.3    Crawford, F.4    Fang, C.5    Mullan, M.6
  • 75
    • 84873343739 scopus 로고    scopus 로고
    • Secretome analyses of Abeta (1-42) stimulated hippocampal astrocytes reveal that CXCL10 is involved in astrocyte migration
    • Lai W, Wu J, Zou X, Xie J, Zhang L, Zhao X, Zhao M, Wang Q and Ji J. Secretome analyses of Abeta (1-42) stimulated hippocampal astrocytes reveal that CXCL10 is involved in astrocyte migration. J Proteome Res 2013; 12: 832-843.
    • (2013) J Proteome Res , vol.12 , pp. 832-843
    • Lai, W.1    Wu, J.2    Zou, X.3    Xie, J.4    Zhang, L.5    Zhao, X.6    Zhao, M.7    Wang, Q.8    Ji, J.9
  • 76
    • 0034042595 scopus 로고    scopus 로고
    • Interleukin-1 promotes expression and phosphorylation of neurofilament and tau proteins in vivo
    • Sheng J, Zhu S, Jones R, Griffin W and Mrak R. Interleukin-1 promotes expression and phosphorylation of neurofilament and tau proteins in vivo. Exp Neurol 2000; 163: 388-391.
    • (2000) Exp Neurol , vol.163 , pp. 388-391
    • Sheng, J.1    Zhu, S.2    Jones, R.3    Griffin, W.4    Mrak, R.5
  • 77
    • 0035865331 scopus 로고    scopus 로고
    • CXC chemokine receptor 4 expression and function in human astroglioma cells
    • Oh JW, Drabik K, Kutsch O, Choi C, Tousson A and Benveniste EN. CXC chemokine receptor 4 expression and function in human astroglioma cells. J Immunol 2001; 166: 2695-2704.
    • (2001) J Immunol , vol.166 , pp. 2695-2704
    • Oh, J.W.1    Drabik, K.2    Kutsch, O.3    Choi, C.4    Tousson, A.5    Benveniste, E.N.6
  • 78
    • 0036592636 scopus 로고    scopus 로고
    • Amyloid β-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer's disease brain exists
    • Allan Butterfield D, Griffin S, Munch G and Pasinetti GM. Amyloid β-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer's disease brain exists. J Alzheimers Dis 2002; 4: 193-201.
    • (2002) J Alzheimers Dis , vol.4 , pp. 193-201
    • Allan Butterfield, D.1    Griffin, S.2    Munch, G.3    Pasinetti, G.M.4
  • 80
    • 0032917904 scopus 로고    scopus 로고
    • Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease
    • Xia MQ and Hyman BT. Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease. J Neurovirol 1999; 5: 32-41.
    • (1999) J Neurovirol , vol.5 , pp. 32-41
    • Xia, M.Q.1    Hyman, B.T.2
  • 82
    • 84862295506 scopus 로고    scopus 로고
    • Sweepers in the CNS: microglial migration and phagocytosis in the alzheimer disease pathogenesis
    • Noda M and Suzumura A. Sweepers in the CNS: microglial migration and phagocytosis in the alzheimer disease pathogenesis. Int J Alzheimers Dis 2012; 2012: 891087.
    • (2012) Int J Alzheimers Dis , vol.2012 , pp. 891087
    • Noda, M.1    Suzumura, A.2
  • 85
    • 71349085295 scopus 로고    scopus 로고
    • Peripheral T cells derived from Alzheimer's disease patients overexpress CXCR2 contributing to its transendothelial migration, which is microglial TNF-α-dependent
    • Liu YJ, Guo DW, Tian L, Shang DS, Zhao WD, Li B, Fang WG, Zhu L and Chen YH. Peripheral T cells derived from Alzheimer's disease patients overexpress CXCR2 contributing to its transendothelial migration, which is microglial TNF-α-dependent. Neurobiol Aging 2010; 31: 175-188.
    • (2010) Neurobiol Aging , vol.31 , pp. 175-188
    • Liu, Y.J.1    Guo, D.W.2    Tian, L.3    Shang, D.S.4    Zhao, W.D.5    Li, B.6    Fang, W.G.7    Zhu, L.8    Chen, Y.H.9
  • 86
    • 79955007180 scopus 로고    scopus 로고
    • IL-9 promotes Th17 cell migration into the central nervous system via CC chemokine ligand-20 produced by astrocytes
    • Zhou Y, Sonobe Y, Akahori T, Jin S, Kawanokuchi J, Noda M, Iwakura Y, Mizuno T and Suzumura A. IL-9 promotes Th17 cell migration into the central nervous system via CC chemokine ligand-20 produced by astrocytes. J Immunol 2011; 186: 4415-4421.
    • (2011) J Immunol , vol.186 , pp. 4415-4421
    • Zhou, Y.1    Sonobe, Y.2    Akahori, T.3    Jin, S.4    Kawanokuchi, J.5    Noda, M.6    Iwakura, Y.7    Mizuno, T.8    Suzumura, A.9
  • 87
    • 0031024047 scopus 로고    scopus 로고
    • Differential production of and migratory response to β chemokines by human microglia and astrocytes
    • Peterson PK, Hu S, Salak-Johnson J, Molitor TW and Chao CC. Differential production of and migratory response to β chemokines by human microglia and astrocytes. J Infect Dis 1997; 175: 478-481.
    • (1997) J Infect Dis , vol.175 , pp. 478-481
    • Peterson, P.K.1    Hu, S.2    Salak-Johnson, J.3    Molitor, T.W.4    Chao, C.C.5
  • 88
    • 84884150739 scopus 로고    scopus 로고
    • Suppression of central chemokine fractalkine receptor signaling alleviates amyloid-induced memory deficiency
    • Wu J, Bie B, Yang H, Xu JJ, Brown DL and Naguib M. Suppression of central chemokine fractalkine receptor signaling alleviates amyloid-induced memory deficiency. Neurobiol Aging 2013; 34: 2843-2852.
    • (2013) Neurobiol Aging , vol.34 , pp. 2843-2852
    • Wu, J.1    Bie, B.2    Yang, H.3    Xu, J.J.4    Brown, D.L.5    Naguib, M.6
  • 90
    • 84861230070 scopus 로고    scopus 로고
    • Stromal cell-derived factor 1alpha decreases beta-amyloid deposition in Alzheimer's disease mouse model
    • Wang Q, Xu Y, Chen JC, Qin YY, Liu M, Liu Y, Xie MJ, Yu ZY, Zhu Z and Wang W. Stromal cell-derived factor 1alpha decreases beta-amyloid deposition in Alzheimer's disease mouse model. Brain Res 2012; 1459: 15-26.
    • (2012) Brain Res , vol.1459 , pp. 15-26
    • Wang, Q.1    Xu, Y.2    Chen, J.C.3    Qin, Y.Y.4    Liu, M.5    Liu, Y.6    Xie, M.J.7    Yu, Z.Y.8    Zhu, Z.9    Wang, W.10
  • 91
    • 0028937265 scopus 로고
    • Enhanced processing of APP induced by IL-1 beta can be reduced by indomethacin and nordihydroguaiaretic acid
    • Dash PK and Moore AN. Enhanced processing of APP induced by IL-1 beta can be reduced by indomethacin and nordihydroguaiaretic acid. Biochem Biophys Res Commun 1995; 208: 542-548.
    • (1995) Biochem Biophys Res Commun , vol.208 , pp. 542-548
    • Dash, P.K.1    Moore, A.N.2
  • 92
    • 0030014166 scopus 로고    scopus 로고
    • IL-1 and anti-inflammatory drugs modulate A beta cytotoxicity in PC12 cells
    • Fagarasan MO and Aisen PS. IL-1 and anti-inflammatory drugs modulate A beta cytotoxicity in PC12 cells. Brain Res 1996; 723: 231-234.
    • (1996) Brain Res , vol.723 , pp. 231-234
    • Fagarasan, M.O.1    Aisen, P.S.2
  • 93
    • 0028812570 scopus 로고
    • Interleukin-6 selectively enhances the intracellular calcium response to NMDA in developing CNS neurons
    • Qiu Z, Parsons KL and Gruol DL. Interleukin-6 selectively enhances the intracellular calcium response to NMDA in developing CNS neurons. J Neurosci 1995; 15: 6688-6699.
    • (1995) J Neurosci , vol.15 , pp. 6688-6699
    • Qiu, Z.1    Parsons, K.L.2    Gruol, D.L.3
  • 94
    • 84887489607 scopus 로고    scopus 로고
    • The chemokine receptor CCR1 is constitutively active, which leads to G protein-independent, beta-arrestin-mediated internalization
    • Gilliland CT, Salanga CL, Kawamura T, Trejo J and Handel TM. The chemokine receptor CCR1 is constitutively active, which leads to G protein-independent, beta-arrestin-mediated internalization. J Biol Chem 2013; 288: 32194-32210.
    • (2013) J Biol Chem , vol.288 , pp. 32194-32210
    • Gilliland, C.T.1    Salanga, C.L.2    Kawamura, T.3    Trejo, J.4    Handel, T.M.5
  • 95
    • 62249200515 scopus 로고    scopus 로고
    • Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway
    • Vukic V, Callaghan D, Walker D, Lue LF, Liu QY, Couraud PO, Romero IA, Weksler B, Stanimirovic DB and Zhang W. Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway. Neurobiol Dis 2009; 34: 95-106.
    • (2009) Neurobiol Dis , vol.34 , pp. 95-106
    • Vukic, V.1    Callaghan, D.2    Walker, D.3    Lue, L.F.4    Liu, Q.Y.5    Couraud, P.O.6    Romero, I.A.7    Weksler, B.8    Stanimirovic, D.B.9    Zhang, W.10
  • 96
    • 0036007160 scopus 로고    scopus 로고
    • GROa/KC, a chemokine receptor CXCR2 ligand, can be a potent trigger for neuronal ERK1/2 and PI-3 kinase pathways and for tau hyperphosphorylation-a role in Alzheimer's disease?
    • Xia M and Hyman BT. GROa/KC, a chemokine receptor CXCR2 ligand, can be a potent trigger for neuronal ERK1/2 and PI-3 kinase pathways and for tau hyperphosphorylation-a role in Alzheimer's disease? J Neuroimmunol 2002; 122: 55-64.
    • (2002) J Neuroimmunol , vol.122 , pp. 55-64
    • Xia, M.1    Hyman, B.T.2
  • 98
    • 84872354623 scopus 로고    scopus 로고
    • CCL2 affects beta-amyloidosis and progressive neurocognitive dysfunction in a mouse model of Alzheimer's disease
    • Kiyota T, Gendelman HE, Weir RA, Higgins EE, Zhang G and Jain M. CCL2 affects beta-amyloidosis and progressive neurocognitive dysfunction in a mouse model of Alzheimer's disease. Neurobiol Aging 2013; 34: 1060-1068.
    • (2013) Neurobiol Aging , vol.34 , pp. 1060-1068
    • Kiyota, T.1    Gendelman, H.E.2    Weir, R.A.3    Higgins, E.E.4    Zhang, G.5    Jain, M.6
  • 99
    • 34147115541 scopus 로고    scopus 로고
    • Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
    • El Khoury J, Toft M, Hickman SE, Means TK, Terada K, Geula C and Luster AD. Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease. Nat Med 2007; 13: 432-438.
    • (2007) Nat Med , vol.13 , pp. 432-438
    • El Khoury, J.1    Toft, M.2    Hickman, S.E.3    Means, T.K.4    Terada, K.5    Geula, C.6    Luster, A.D.7
  • 100
    • 79955775349 scopus 로고    scopus 로고
    • CC chemokine receptor 2 deficiency aggravates cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease
    • Naert G and Rivest S. CC chemokine receptor 2 deficiency aggravates cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease. J Neurosci 2011; 31: 6208-6220.
    • (2011) J Neurosci , vol.31 , pp. 6208-6220
    • Naert, G.1    Rivest, S.2
  • 101
    • 58149392087 scopus 로고    scopus 로고
    • Astrocyte-derived MCP-1 mediates neuroprotective effects of noradrenaline
    • Madrigal JL, Leza JC, Polak P, Kalinin S and Feinstein DL. Astrocyte-derived MCP-1 mediates neuroprotective effects of noradrenaline. J Neurosci 2009; 29: 263-267.
    • (2009) J Neurosci , vol.29 , pp. 263-267
    • Madrigal, J.L.1    Leza, J.C.2    Polak, P.3    Kalinin, S.4    Feinstein, D.L.5
  • 103
    • 77957316313 scopus 로고    scopus 로고
    • CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models
    • Lee S, Varvel NH, Konerth ME, Xu G, Cardona AE, Ransohoff RM and Lamb BT. CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models. Am J Pathol 2010; 177: 2549-2562.
    • (2010) Am J Pathol , vol.177 , pp. 2549-2562
    • Lee, S.1    Varvel, N.H.2    Konerth, M.E.3    Xu, G.4    Cardona, A.E.5    Ransohoff, R.M.6    Lamb, B.T.7
  • 106
    • 80052714655 scopus 로고    scopus 로고
    • CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease
    • Cho SH, Sun B, Zhou Y, Kauppinen TM, Halabisky B, Wes P, Ransohoff RM and Gan L. CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease. J Biol Chem 2011; 286: 32713-32722.
    • (2011) J Biol Chem , vol.286 , pp. 32713-32722
    • Cho, S.H.1    Sun, B.2    Zhou, Y.3    Kauppinen, T.M.4    Halabisky, B.5    Wes, P.6    Ransohoff, R.M.7    Gan, L.8
  • 107
    • 52449118875 scopus 로고    scopus 로고
    • Decreased CXCL12 (SDF-1) plasma levels in early Alzheimer's disease: a contribution to a deficient hematopoietic brain support?
    • Laske C, Stellos K, Eschweiler GW, Leyhe T and Gawaz M. Decreased CXCL12 (SDF-1) plasma levels in early Alzheimer's disease: a contribution to a deficient hematopoietic brain support? J Alzheimers Dis 2008; 15: 83-95.
    • (2008) J Alzheimers Dis , vol.15 , pp. 83-95
    • Laske, C.1    Stellos, K.2    Eschweiler, G.W.3    Leyhe, T.4    Gawaz, M.5
  • 108
    • 40849112965 scopus 로고    scopus 로고
    • Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition
    • Parachikova A, Nichol KE and Cotman CW. Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition. Neurobiol Dis 2008; 30: 121-129.
    • (2008) Neurobiol Dis , vol.30 , pp. 121-129
    • Parachikova, A.1    Nichol, K.E.2    Cotman, C.W.3
  • 109
    • 42549169556 scopus 로고    scopus 로고
    • Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid
    • Nichol KE, Poon WW, Parachikova AI, Cribbs DH, Glabe CG and Cotman CW. Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid. J Neuroinflammation 2008; 5: 13.
    • (2008) J Neuroinflammation , vol.5 , pp. 13
    • Nichol, K.E.1    Poon, W.W.2    Parachikova, A.I.3    Cribbs, D.H.4    Glabe, C.G.5    Cotman, C.W.6
  • 110
    • 35349020900 scopus 로고    scopus 로고
    • Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease
    • Parachikova A and Cotman CW. Reduced CXCL12/CXCR4 results in impaired learning and is downregulated in a mouse model of Alzheimer disease. Neurobiol Dis 2007; 28: 143-153.
    • (2007) Neurobiol Dis , vol.28 , pp. 143-153
    • Parachikova, A.1    Cotman, C.W.2
  • 111
    • 0032247897 scopus 로고    scopus 로고
    • Astrocyte-mediated potentiation of inhibitory synaptic transmission
    • Kang J, Jiang L, Goldman SA and Nedergaard M. Astrocyte-mediated potentiation of inhibitory synaptic transmission. Nat Neurosci 1998; 1: 683-692.
    • (1998) Nat Neurosci , vol.1 , pp. 683-692
    • Kang, J.1    Jiang, L.2    Goldman, S.A.3    Nedergaard, M.4
  • 112
    • 0034161522 scopus 로고    scopus 로고
    • Imaging extracellular waves of glutamate during calcium signaling in cultured astrocytes
    • Innocenti B, Parpura V and Haydon PG. Imaging extracellular waves of glutamate during calcium signaling in cultured astrocytes. J Neurosci 2000; 20: 1800-1808.
    • (2000) J Neurosci , vol.20 , pp. 1800-1808
    • Innocenti, B.1    Parpura, V.2    Haydon, P.G.3
  • 114
    • 3543100441 scopus 로고    scopus 로고
    • The chemokine receptor CCR5-Delta32 gene mutation is not protective against Alzheimer's disease
    • Combarros O, Infante J, Llorca J, Pena N, Fernandez-Viadero C and Berciano J. The chemokine receptor CCR5-Delta32 gene mutation is not protective against Alzheimer's disease. Neurosci Lett 2004; 366: 312-314.
    • (2004) Neurosci Lett , vol.366 , pp. 312-314
    • Combarros, O.1    Infante, J.2    Llorca, J.3    Pena, N.4    Fernandez-Viadero, C.5    Berciano, J.6
  • 115
    • 77957367692 scopus 로고    scopus 로고
    • Morphine induces the release of CCL5 from astrocytes: potential neuroprotective mechanism against the HIV protein gp120
    • Avdoshina V, Biggio F, Palchik G, Campbell LA and Mocchetti I. Morphine induces the release of CCL5 from astrocytes: potential neuroprotective mechanism against the HIV protein gp120. Glia 2010; 58: 1630-1639.
    • (2010) Glia , vol.58 , pp. 1630-1639
    • Avdoshina, V.1    Biggio, F.2    Palchik, G.3    Campbell, L.A.4    Mocchetti, I.5
  • 116
    • 0034256053 scopus 로고    scopus 로고
    • Expression of the chemokine receptor CXCR3 on neurons and the elevated expression of its ligand IP-10 in reactive astrocytes: in vitro ERK1/2 activation and role in Alzheimer's disease
    • Xia MQ, Bacskai BJ, Knowles RB, Qin SX and Hyman BT. Expression of the chemokine receptor CXCR3 on neurons and the elevated expression of its ligand IP-10 in reactive astrocytes: in vitro ERK1/2 activation and role in Alzheimer's disease. J Neuroimmunol 2000; 108: 227-235.
    • (2000) J Neuroimmunol , vol.108 , pp. 227-235
    • Xia, M.Q.1    Bacskai, B.J.2    Knowles, R.B.3    Qin, S.X.4    Hyman, B.T.5
  • 117
    • 33751104457 scopus 로고    scopus 로고
    • Broad-spectrum effects of 4-aminopyridine to modulate amyloid β1-42-induced cell signaling and functional responses in human microglia
    • Franciosi S, Ryu JK, Choi HB, Radov L, Kim SU and McLarnon JG. Broad-spectrum effects of 4-aminopyridine to modulate amyloid β1-42-induced cell signaling and functional responses in human microglia. J Neurosci 2006; 26: 11652-11664.
    • (2006) J Neurosci , vol.26 , pp. 11652-11664
    • Franciosi, S.1    Ryu, J.K.2    Choi, H.B.3    Radov, L.4    Kim, S.U.5    McLarnon, J.G.6
  • 118
    • 0034717942 scopus 로고    scopus 로고
    • The role of complement anaphylatoxin C5a in neurodegeneration: implications in Alzheimer's disease
    • Mukherjee P and Pasinetti GM. The role of complement anaphylatoxin C5a in neurodegeneration: implications in Alzheimer's disease. J neuroimmunol 2000; 105: 124-130.
    • (2000) J neuroimmunol , vol.105 , pp. 124-130
    • Mukherjee, P.1    Pasinetti, G.M.2
  • 119
    • 0037468398 scopus 로고    scopus 로고
    • Complement component anaphylatoxins upregulate chemokine expression by human astrocytes
    • Jauneau AC, Ischenko A, Chan P and Fontaine M. Complement component anaphylatoxins upregulate chemokine expression by human astrocytes. FEBS Lett 2003; 537: 17-22.
    • (2003) FEBS Lett , vol.537 , pp. 17-22
    • Jauneau, A.C.1    Ischenko, A.2    Chan, P.3    Fontaine, M.4
  • 120
    • 0034918334 scopus 로고    scopus 로고
    • RANTES: a versatile and controversial chemokine
    • Appay V and Rowland-Jones SL. RANTES: a versatile and controversial chemokine. Trends Immunol 2001; 22: 83-87.
    • (2001) Trends Immunol , vol.22 , pp. 83-87
    • Appay, V.1    Rowland-Jones, S.L.2
  • 121
    • 79956033909 scopus 로고    scopus 로고
    • Curcumin enhances neuronal survival in N-methyl-d-aspartic acid toxicity by inducing RANTES expression in astrocytes via PI-3K and MAPK signaling pathways
    • Lin MS, Hung KS, Chiu WT, Sun YY, Tsai SH, Lin JW and Lee YH. Curcumin enhances neuronal survival in N-methyl-d-aspartic acid toxicity by inducing RANTES expression in astrocytes via PI-3K and MAPK signaling pathways. Prog NeuroPsychopharmacol Biol Psychiatry 2011; 35: 931-938.
    • (2011) Prog NeuroPsychopharmacol Biol Psychiatry , vol.35 , pp. 931-938
    • Lin, M.S.1    Hung, K.S.2    Chiu, W.T.3    Sun, Y.Y.4    Tsai, S.H.5    Lin, J.W.6    Lee, Y.H.7
  • 123
    • 85043217965 scopus 로고    scopus 로고
    • P273 Beneficial effect of C-C chemokine receptor type 5 antagonist, as an add-on treatment for HIV-1 patients with virological response but no immunological response
    • Murata M, Furusyo N and Hayashi J. P273 Beneficial effect of C-C chemokine receptor type 5 antagonist, as an add-on treatment for HIV-1 patients with virological response but no immunological response. Intl J Antimicrobial Agents 2013; 42 Suppl 2: S128.
    • (2013) Intl J Antimicrobial Agents , vol.42
    • Murata, M.1    Furusyo, N.2    Hayashi, J.3


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