Expression of the chemokine receptor CXCR3 on neurons and the elevated expression of its ligand IP-10 in reactive astrocytes: In vitro ERK1/2 activation and role in Alzheimer's disease

Journal of Neuroimmunology

Volumn 108, Issue 1-2, 2000, Pages 227-235

  Xia, Meng Qi ^a   Bacskai, Brian J ^a   Knowles, Roger B ^a,c   Qin, Shi Xin ^b   Hyman, Bradley T ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

^c Drew University   (United States)

Author keywords

Alzheimer's disease; Chemokine receptor; CNS; CXCR3; IP 10; MIP 1

Indexed keywords

CHEMOKINE RECEPTOR CCR3; LIGAND; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE;

ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN; BRAIN CORTEX; CONTROLLED STUDY; ENZYME ACTIVATION; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; SENILE PLAQUE;

AGED; ALZHEIMER DISEASE; ANIMALS; ASTROCYTES; CELLS, CULTURED; CEREBRAL CORTEX; CHEMOKINES, CXC; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION PROFILING; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; MACROPHAGE INFLAMMATORY PROTEIN-1; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; PHOSPHORYLATION; PYRIMIDINONES; RECEPTORS, CHEMOKINE; SENILE PLAQUES; THIAZOLES; UP-REGULATION;

EID: 0034256053     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(00)00285-X     Document Type: Article

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