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Volumn 6, Issue 3, 2013, Pages 255-263

Coronary heart disease in systemic lupus erythematosus is associated with interferon regulatory factor-8 gene variants

Author keywords

Cardiovascular disease; Carotid intima media thickness; Coronary disease; Genes; Interferon regulatory factor 8; Lupus erythematosus; Myocardial ischemia; Systemic

Indexed keywords

INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; STAT4 PROTEIN;

EID: 84884498097     PISSN: 1942325X     EISSN: 19423268     Source Type: Journal    
DOI: 10.1161/CIRCGENETICS.113.000044     Document Type: Article
Times cited : (39)

References (49)
  • 1
    • 82555196095 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • Tsokos GC. Systemic lupus erythematosus. N Engl J Med. 2011;365: 2110-2121.
    • (2011) N Engl J Med , vol.365 , pp. 2110-2121
    • Tsokos, G.C.1
  • 2
    • 79953161285 scopus 로고    scopus 로고
    • The type i interferon system in the development of lupus
    • Rönnblom L, Alm GV, Eloranta ML. The type I interferon system in the development of lupus. Semin Immunol. 2011;23:113-121.
    • (2011) Semin Immunol , vol.23 , pp. 113-121
    • Rönnblom, L.1    Alm, G.V.2    Eloranta, M.L.3
  • 4
    • 0034761724 scopus 로고    scopus 로고
    • Traditional framingham risk factors fail to fully account for accelerated atherosclerosis in systemic lupus erythematosus
    • Esdaile JM, Abrahamowicz M, Grodzicky T, Li Y, Panaritis C, du Berger R, et al. Traditional Framingham risk factors fail to fully account for accelerated atherosclerosis in systemic lupus erythematosus. Arthritis Rheum. 2001;44:2331-2337.
    • (2001) Arthritis Rheum , vol.44 , pp. 2331-2337
    • Esdaile, J.M.1    Abrahamowicz, M.2    Grodzicky, T.3    Li, Y.4    Panaritis, C.5    Du Berger, R.6
  • 5
    • 0031052874 scopus 로고    scopus 로고
    • Age-specific incidence rates of myocardial infarction and angina in women with systemic lupus erythematosus: Comparison with the framingham study
    • Manzi S, Meilahn EN, Rairie JE, Conte CG, Medsger TA Jr, Jansen-McWilliams L, et al. Age-specific incidence rates of myocardial infarction and angina in women with systemic lupus erythematosus: comparison with the Framingham Study. Am J Epidemiol. 1997;145:408-415.
    • (1997) Am J Epidemiol , vol.145 , pp. 408-415
    • Manzi, S.1    Meilahn, E.N.2    Rairie, J.E.3    Conte, C.G.4    Medsger Jr., T.A.5    Jansen-McWilliams, L.6
  • 7
    • 1842530440 scopus 로고    scopus 로고
    • Cardiovascular disease a hazard despite improved prognosis in patients with systemic lupus erythematosus: Results from a swedish population based study 1964-95
    • Björnadal L, Yin L, Granath F, Klareskog L, Ekbom A. Cardiovascular disease a hazard despite improved prognosis in patients with systemic lupus erythematosus: results from a Swedish population based study 1964-95. J Rheumatol. 2004;31:713-719.
    • (2004) J Rheumatol , vol.31 , pp. 713-719
    • Björnadal, L.1    Yin, L.2    Granath, F.3    Klareskog, L.4    Ekbom, A.5
  • 9
    • 77952469211 scopus 로고    scopus 로고
    • Predictors of the first cardiovascular event in patients with systemic lupus erythematosus: A prospective cohort study
    • Gustafsson J, Gunnarsson I, Börjesson O, Pettersson S, Möller S, Fei GZ, et al. Predictors of the first cardiovascular event in patients with systemic lupus erythematosus: a prospective cohort study. Arthritis Res Ther. 2009;11:R186.
    • (2009) Arthritis Res Ther , vol.11
    • Gustafsson, J.1    Gunnarsson, I.2    Börjesson, O.3    Pettersson, S.4    Möller, S.5    Fei, G.Z.6
  • 10
    • 79952803066 scopus 로고    scopus 로고
    • Glomerular filtration rate predicts arterial events in women with systemic lupus erythematosus
    • Zhang W, Aghdassi E, Reich HN, Su J, Lou W, Landolt-Marticorena C, et al. Glomerular filtration rate predicts arterial events in women with systemic lupus erythematosus. Rheumatology (Oxford). 2011;50:799-805.
    • (2011) Rheumatology (Oxford , vol.50 , pp. 799-805
    • Zhang, W.1    Aghdassi, E.2    Reich, H.N.3    Su, J.4    Lou, W.5    Landolt-Marticorena, C.6
  • 11
    • 2342521933 scopus 로고    scopus 로고
    • Endothelial cell apoptosis in systemic lupus erythematosus: A common pathway for abnormal vascular function and thrombosis propensity
    • Rajagopalan S, Somers EC, Brook RD, Kehrer C, Pfenninger D, Lewis E, et al. Endothelial cell apoptosis in systemic lupus erythematosus: a common pathway for abnormal vascular function and thrombosis propensity. Blood. 2004;103:3677-3683.
    • (2004) Blood , vol.103 , pp. 3677-3683
    • Rajagopalan, S.1    Somers, E.C.2    Brook, R.D.3    Kehrer, C.4    Pfenninger, D.5    Lewis, E.6
  • 12
    • 36049038869 scopus 로고    scopus 로고
    • Type i interferon as a novel risk factor for endothelial progenitor cell depletion and endothelial dysfunction in systemic lupus erythematosus
    • Lee PY, Li Y, Richards HB, Chan FS, Zhuang H, Narain S, et al. Type I interferon as a novel risk factor for endothelial progenitor cell depletion and endothelial dysfunction in systemic lupus erythematosus. Arthritis Rheum. 2007;56:3759-3769.
    • (2007) Arthritis Rheum , vol.56 , pp. 3759-3769
    • Lee, P.Y.1    Li, Y.2    Richards, H.B.3    Chan, F.S.4    Zhuang, H.5    Narain, S.6
  • 15
    • 79551672352 scopus 로고    scopus 로고
    • How does interferon-α insult the vasculature? Let me count the ways
    • Kaplan MJ, Salmon JE. How does interferon-α insult the vasculature? Let me count the ways. Arthritis Rheum. 2011;63:334-336.
    • (2011) Arthritis Rheum , vol.63 , pp. 334-336
    • Kaplan, M.J.1    Salmon, J.E.2
  • 16
    • 40049108936 scopus 로고    scopus 로고
    • Association of systemic lupus erythematosus with c8orf13-blk and itgam-itgax
    • Hom G, Graham RR, Modrek B, Taylor KE, Ortmann W, Garnier S, et al. Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med. 2008;358:900-909.
    • (2008) N Engl J Med , vol.358 , pp. 900-909
    • Hom, G.1    Graham, R.R.2    Modrek, B.3    Taylor, K.E.4    Ortmann, W.5    Garnier, S.6
  • 18
    • 67849099131 scopus 로고    scopus 로고
    • Recent insights into the genetic basis of systemic lupus erythematosus
    • Moser KL, Kelly JA, Lessard CJ, Harley JB. Recent insights into the genetic basis of systemic lupus erythematosus. Genes Immun. 2009;10:373-379.
    • (2009) Genes Immun , vol.10 , pp. 373-379
    • Moser, K.L.1    Kelly, J.A.2    Lessard, C.J.3    Harley, J.B.4
  • 19
    • 50849101942 scopus 로고    scopus 로고
    • A risk haplotype of stat4 for systemic lupus erythematosus is overexpressed, correlates with anti-dsdna and shows additive effects with two risk alleles of irf5
    • Sigurdsson S, Nordmark G, Garnier S, Grundberg E, Kwan T, Nilsson O, et al. A risk haplotype of STAT4 for systemic lupus erythematosus is overexpressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5. Hum Mol Genet. 2008;17:2868-2876.
    • (2008) Hum Mol Genet , vol.17 , pp. 2868-2876
    • Sigurdsson, S.1    Nordmark, G.2    Garnier, S.3    Grundberg, E.4    Kwan, T.5    Nilsson, O.6
  • 20
    • 79953743757 scopus 로고    scopus 로고
    • Differential genetic associations for systemic lupus erythematosus based on anti-dsdna autoantibody production
    • SLEGEN
    • Chung SA, Taylor KE, Graham RR, Nititham J, Lee AT, Ortmann WA, et al.; SLEGEN. Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. PLoS Genet. 2011;7:e1001323.
    • (2011) PLoS Genet , vol.7
    • Chung, S.A.1    Taylor, K.E.2    Graham, R.R.3    Nititham, J.4    Lee, A.T.5    Ortmann, W.A.6
  • 21
    • 79952261842 scopus 로고    scopus 로고
    • Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes
    • Taylor KE, Chung SA, Graham RR, Ortmann WA, Lee AT, Langefeld CD, et al. Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes. PLoS Genet. 2011;7:e1001311.
    • (2011) PLoS Genet , vol.7
    • Taylor, K.E.1    Chung, S.A.2    Graham, R.R.3    Ortmann, W.A.4    Lee, A.T.5    Langefeld, C.D.6
  • 22
    • 77951563846 scopus 로고    scopus 로고
    • A stat4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus
    • Svenungsson E, Gustafsson J, Leonard D, Sandling J, Gunnarsson I, Nordmark G, et al. A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus. Ann Rheum Dis. 2010;69:834-840.
    • (2010) Ann Rheum Dis , vol.69 , pp. 834-840
    • Svenungsson, E.1    Gustafsson, J.2    Leonard, D.3    Sandling, J.4    Gunnarsson, I.5    Nordmark, G.6
  • 24
    • 13344270914 scopus 로고    scopus 로고
    • The development and initial validation of the systemic lupus international collaborating clinics/american college of rheumatology damage index for systemic lupus erythematosus
    • Gladman D, Ginzler E, Goldsmith C, Fortin P, Liang M, Urowitz M, et al. The development and initial validation of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology damage index for systemic lupus erythematosus. Arthritis Rheum. 1996;39:363-369.
    • (1996) Arthritis Rheum , vol.39 , pp. 363-369
    • Gladman, D.1    Ginzler, E.2    Goldsmith, C.3    Fortin, P.4    Liang, M.5    Urowitz, M.6
  • 25
    • 36548998846 scopus 로고    scopus 로고
    • Joint esc/accf/aha/whf task force for the redefinition of myocardial infarction: Universal definition of myocardial infarction
    • Thygesen K, Alpert JS, White HD, Jaffe AS, Apple FS, Galvani M, et al.; Joint ESC/ACCF/AHA/WHF task force for the redefinition of myocardial infarction: universal definition of myocardial infarction. Circulation. 2007;116:2634-2653.
    • (2007) Circulation , vol.116 , pp. 2634-2653
    • Thygesen, K.1    Alpert, J.S.2    White, H.D.3    Jaffe, A.S.4    Apple, F.S.5    Galvani, M.6
  • 26
    • 0344444877 scopus 로고    scopus 로고
    • Centers for disease control and prevention; and the national heart, lung, and blood institute
    • Case Definitions For Acute Coronary Heart Disease In Epidemiology and Clinical Research Studies: Statement From The AHA Council On Epidemiology and Prevention; AHA Statistics Committee; World Heart Federation Council On Epidemiology and Prevention; The European Society Of Cardiology Working Group On Epidemiology and Prevention
    • Luepker RV, Apple FS, Christenson RH, Crow RS, Fortmann SP, Goff D, et al. Case definitions for acute coronary heart disease in epidemiology and clinical research studies: Statement from the AHA Council on Epidemiology and Prevention; AHA Statistics Committee; World Heart Federation Council on Epidemiology and Prevention; the European Society of Cardiology Working Group on Epidemiology and Prevention; Centers for Disease Control and Prevention; and the National Heart, Lung, and Blood Institute. Circulation. 2003;108:2543-2549.
    • (2003) Circulation , vol.108 , pp. 2543-2549
    • Luepker, R.V.1    Apple, F.S.2    Christenson, R.H.3    Crow, R.S.4    Fortmann, S.P.5    Goff, D.6
  • 27
    • 70350650472 scopus 로고    scopus 로고
    • A large-scale replication study identifies tnip1, prdm1, jazf1, uhrf1bp1 and il10 as risk loci for systemic lupus erythematosus
    • Gateva V, Sandling JK, Hom G, Taylor KE, Chung SA, Sun X, et al. A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. Nat Genet. 2009;41:1228-1233.
    • (2009) Nat Genet , vol.41 , pp. 1228-1233
    • Gateva, V.1    Sandling, J.K.2    Hom, G.3    Taylor, K.E.4    Chung, S.A.5    Sun, X.6
  • 28
    • 0028080286 scopus 로고
    • Methodological considerations of ultrasound investigation of intima-media thickness and lumen diameter
    • Wikstrand J, Wendelhag I. Methodological considerations of ultrasound investigation of intima-media thickness and lumen diameter. J Intern Med. 1994;236:555-559.
    • (1994) J Intern Med , vol.236 , pp. 555-559
    • Wikstrand, J.1    Wendelhag, I.2
  • 30
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of ld and haplotype maps
    • Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005;21:263-265.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 31
    • 45249112573 scopus 로고    scopus 로고
    • Interferon regulatory factor 5 (irf5) gene variants are associated with multiple sclerosis in three distinct populations
    • Kristjansdottir G, Sandling JK, Bonetti A, Roos IM, Milani L, Wang C, et al. Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations. J Med Genet. 2008;45:362-369.
    • (2008) J Med Genet , vol.45 , pp. 362-369
    • Kristjansdottir, G.1    Sandling, J.K.2    Bonetti, A.3    Roos, I.M.4    Milani, L.5    Wang, C.6
  • 33
    • 84859491100 scopus 로고    scopus 로고
    • Identification of irf8, tmem39a, and ikzf3-zpbp2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study
    • BIOLUPUS Network; GENLES Network
    • Lessard CJ, Adrianto I, Ice JA, Wiley GB, Kelly JA, Glenn SB, et al.; BIOLUPUS Network; GENLES Network. Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study. Am J Hum Genet. 2012;90:648-660.
    • (2012) Am J Hum Genet , vol.90 , pp. 648-660
    • Lessard, C.J.1    Adrianto, I.2    Ice, J.A.3    Wiley, G.B.4    Kelly, J.A.5    Glenn, S.B.6
  • 37
    • 66549125977 scopus 로고    scopus 로고
    • Irf8 regulates myeloid and b lymphoid lineage diversification
    • Wang H, Morse HC III. IRF8 regulates myeloid and B lymphoid lineage diversification. Immunol Res. 2009;43:109-117.
    • (2009) Immunol Res , vol.43 , pp. 109-117
    • Wang, H.1    Morse III, H.C.2
  • 38
    • 42649114059 scopus 로고    scopus 로고
    • The irf family transcription factors in immunity and oncogenesis
    • Tamura T, Yanai H, Savitsky D, Taniguchi T. The IRF family transcription factors in immunity and oncogenesis. Annu Rev Immunol. 2008;26:535-584.
    • (2008) Annu Rev Immunol , vol.26 , pp. 535-584
    • Tamura, T.1    Yanai, H.2    Savitsky, D.3    Taniguchi, T.4
  • 39
    • 84859420971 scopus 로고    scopus 로고
    • Auto-Antigenic protein-dna complexes stimulate plasmacytoid dendritic cells to promote atherosclerosis
    • Döring Y, Manthey HD, Drechsler M, Lievens D, Megens RT, Soehnlein O, et al. Auto-Antigenic protein-DNA complexes stimulate plasmacytoid dendritic cells to promote atherosclerosis. Circulation. 2012;125: 1673-1683.
    • (2012) Circulation , vol.125 , pp. 1673-1683
    • Döring, Y.1    Manthey, H.D.2    Drechsler, M.3    Lievens, D.4    Megens, R.T.5    Soehnlein, O.6
  • 40
    • 80855134317 scopus 로고    scopus 로고
    • Irf8 governs expression of genes involved in innate and adaptive immunity in human and mouse germinal center b cells
    • Shin DM, Lee CH, Morse HC III. IRF8 governs expression of genes involved in innate and adaptive immunity in human and mouse germinal center B cells. PLoS One. 2011;6:e27384.
    • (2011) PLoS One , vol.6
    • Shin, D.M.1    Lee, C.H.2    Morse III, H.C.3
  • 41
    • 32644464262 scopus 로고    scopus 로고
    • Irf family proteins and type i interferon induction in dendritic cells
    • Tailor P, Tamura T, Ozato K. IRF family proteins and type I interferon induction in dendritic cells. Cell Res. 2006;16:134-140.
    • (2006) Cell Res , vol.16 , pp. 134-140
    • Tailor, P.1    Tamura, T.2    Ozato, K.3
  • 42
    • 35548948085 scopus 로고    scopus 로고
    • Interferon-Alpha promotes abnormal vasculogenesis in lupus: A potential pathway for premature atherosclerosis
    • Denny MF, Thacker S, Mehta H, Somers EC, Dodick T, Barrat FJ, et al. Interferon-Alpha promotes abnormal vasculogenesis in lupus: a potential pathway for premature atherosclerosis. Blood. 2007;110:2907-2915.
    • (2007) Blood , vol.110 , pp. 2907-2915
    • Denny, M.F.1    Thacker, S.2    Mehta, H.3    Somers, E.C.4    Dodick, T.5    Barrat, F.J.6
  • 43
    • 77956905671 scopus 로고    scopus 로고
    • Platelet transcriptional profile and protein expression in patients with systemic lupus erythematosus: Up-regulation of the type i interferon system is strongly associated with vascular disease
    • Lood C, Amisten S, Gullstrand B, Jönsen A, Allhorn M, Truedsson L, et al. Platelet transcriptional profile and protein expression in patients with systemic lupus erythematosus: up-regulation of the type I interferon system is strongly associated with vascular disease. Blood. 2010;116: 1951-1957.
    • (2010) Blood , vol.116 , pp. 1951-1957
    • Lood, C.1    Amisten, S.2    Gullstrand, B.3    Jönsen, A.4    Allhorn, M.5    Truedsson, L.6
  • 44
    • 79551678138 scopus 로고    scopus 로고
    • Interferon-Alpha priming promotes lipid uptake and macrophage-derived foam cell formation: A novel link between interferon-Alpha and atherosclerosis in lupus
    • Li J, Fu Q, Cui H, Qu B, Pan W, Shen N, et al. Interferon-Alpha priming promotes lipid uptake and macrophage-derived foam cell formation: A novel link between interferon-Alpha and atherosclerosis in lupus. Arthritis Rheum. 2011;63:492-502.
    • (2011) Arthritis Rheum , vol.63 , pp. 492-502
    • Li, J.1    Fu, Q.2    Cui, H.3    Qu, B.4    Pan, W.5    Shen, N.6
  • 45
    • 77958144092 scopus 로고    scopus 로고
    • The detrimental effects of interferon-α on vasculogenesis in lupus are mediated by repression of il-1 pathways: Potential role in atherogenesis and renal vascular rarefaction
    • Thacker SG, Berthier CC, Mattinzoli D, Rastaldi MP, Kretzler M, Kaplan MJ. The detrimental effects of interferon-α on vasculogenesis in lupus are mediated by repression of IL-1 pathways: potential role in atherogenesis and renal vascular rarefaction. J Immunol. 2010;185:4457-4469.
    • (2010) J Immunol , vol.185 , pp. 4457-4469
    • Thacker, S.G.1    Berthier, C.C.2    Mattinzoli, D.3    Rastaldi, M.P.4    Kretzler, M.5    Kaplan, M.J.6
  • 46
    • 84860991009 scopus 로고    scopus 로고
    • Type i interferons are associated with subclinical markers of cardiovascular disease in a cohort of systemic lupus erythematosus patients
    • Somers EC, Zhao W, Lewis EE, Wang L, Wing JJ, Sundaram B, et al. Type I interferons are associated with subclinical markers of cardiovascular disease in a cohort of systemic lupus erythematosus patients. PLoS One. 2012;7:e37000.
    • (2012) PLoS One , vol.7
    • Somers, E.C.1    Zhao, W.2    Lewis, E.E.3    Wang, L.4    Wing, J.J.5    Sundaram, B.6
  • 47
    • 35648992465 scopus 로고    scopus 로고
    • Synergistic proinflammatory effects of the antiviral cytokine interferon-Alpha and toll-like receptor 4 ligands in the atherosclerotic plaque
    • Niessner A, Shin MS, Pryshchep O, Goronzy JJ, Chaikof EL, Weyand CM. Synergistic proinflammatory effects of the antiviral cytokine interferon-Alpha and Toll-like receptor 4 ligands in the atherosclerotic plaque. Circulation. 2007;116:2043-2052.
    • (2007) Circulation , vol.116 , pp. 2043-2052
    • Niessner, A.1    Shin, M.S.2    Pryshchep, O.3    Goronzy, J.J.4    Chaikof, E.L.5    Weyand, C.M.6
  • 48
    • 33845428041 scopus 로고    scopus 로고
    • Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic t-cell function in the atherosclerotic plaque through interferon-Alpha
    • Niessner A, Sato K, Chaikof EL, Colmegna I, Goronzy JJ, Weyand CM. Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-Alpha. Circulation. 2006;114:2482-2489.
    • (2006) Circulation , vol.114 , pp. 2482-2489
    • Niessner, A.1    Sato, K.2    Chaikof, E.L.3    Colmegna, I.4    Goronzy, J.J.5    Weyand, C.M.6
  • 49
    • 80052737713 scopus 로고    scopus 로고
    • Current understanding of the role of b cell subsets and intimal and adventitial b cells in atherosclerosis
    • Kyaw T, Tipping P, Toh BH, Bobik A. Current understanding of the role of B cell subsets and intimal and adventitial B cells in atherosclerosis. Curr Opin Lipidol. 2011;22:373-379.
    • (2011) Curr Opin Lipidol , vol.22 , pp. 373-379
    • Kyaw, T.1    Tipping, P.2    Toh, B.H.3    Bobik, A.4


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