-
1
-
-
77956328616
-
Interleukin-9 as a T helper type 17 cytokine
-
Nowak EC, Noelle RJ (2010) Interleukin-9 as a T helper type 17 cytokine. Immunology 131:169-173.
-
(2010)
Immunology
, vol.131
, pp. 169-173
-
-
Nowak, E.C.1
Noelle, R.J.2
-
2
-
-
0034606359
-
Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production
-
Breitfeld D, et al. (2000) Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production. J Exp Med 192: 1545-1552.
-
(2000)
J Exp Med
, vol.192
, pp. 1545-1552
-
-
Breitfeld, D.1
-
3
-
-
0034606348
-
CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function
-
Schaerli P, et al. (2000) CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function. J Exp Med 192:1553-1562.
-
(2000)
J Exp Med
, vol.192
, pp. 1553-1562
-
-
Schaerli, P.1
-
4
-
-
65549114338
-
IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells
-
King IL, Mohrs M (2009) IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells. J Exp Med 206:1001-1007.
-
(2009)
J Exp Med
, vol.206
, pp. 1001-1007
-
-
King, I.L.1
Mohrs, M.2
-
5
-
-
62849090439
-
Cytokine-secreting follicular T cells shape the antibody repertoire
-
Reinhardt RL, Liang HE, Locksley RM (2009) Cytokine-secreting follicular T cells shape the antibody repertoire. Nat Immunol 10:385-393.
-
(2009)
Nat Immunol
, vol.10
, pp. 385-393
-
-
Reinhardt, R.L.1
Liang, H.E.2
Locksley, R.M.3
-
6
-
-
2942755979
-
T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells
-
Chtanova T, et al. (2004) T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells. J Immunol 173:68-78. (Pubitemid 38797327)
-
(2004)
Journal of Immunology
, vol.173
, Issue.1
, pp. 68-78
-
-
Chtanova, T.1
Tangye, S.G.2
Newton, R.3
Frank, N.4
Hodge, M.R.5
Rolph, M.S.6
Mackay, C.R.7
-
7
-
-
38049101408
-
Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: Predominant role of IL-21 produced by CXCR5+ T follicular helper cells
-
Bryant VL, et al. (2007) Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: Predominant role of IL-21 produced by CXCR5+ T follicular helper cells. J Immunol 179:8180-8190.
-
(2007)
J Immunol
, vol.179
, pp. 8180-8190
-
-
Bryant, V.L.1
-
8
-
-
77149122105
-
IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses
-
Linterman MA, et al. (2010) IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses. J Exp Med 207:353-363.
-
(2010)
J Exp Med
, vol.207
, pp. 353-363
-
-
Linterman, M.A.1
-
9
-
-
46749115446
-
A fundamental role for interleukin-21 in the generation of T follicular helper cells
-
Vogelzang A, et al. (2008) A fundamental role for interleukin-21 in the generation of T follicular helper cells. Immunity 29:127-137.
-
(2008)
Immunity
, vol.29
, pp. 127-137
-
-
Vogelzang, A.1
-
10
-
-
77149142640
-
IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism
-
Zotos D, et al. (2010) IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism. J Exp Med 207:365-378.
-
(2010)
J Exp Med
, vol.207
, pp. 365-378
-
-
Zotos, D.1
-
11
-
-
69249109601
-
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation
-
Johnston RJ, et al. (2009) Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science 325:1006-1010.
-
(2009)
Science
, vol.325
, pp. 1006-1010
-
-
Johnston, R.J.1
-
12
-
-
69249101229
-
Bcl6 mediates the development of T follicular helper cells
-
Nurieva RI, et al. (2009) Bcl6 mediates the development of T follicular helper cells. Science 325:1001-1005.
-
(2009)
Science
, vol.325
, pp. 1001-1005
-
-
Nurieva, R.I.1
-
13
-
-
70049101558
-
The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment
-
Yu D, et al. (2009) The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment. Immunity 31:457-468.
-
(2009)
Immunity
, vol.31
, pp. 457-468
-
-
Yu, D.1
-
14
-
-
23444434705
-
+ follicular B helper T cell maintenance in vivo
-
Akiba H, et al. (2005) The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo. J Immunol 175:2340-2348. (Pubitemid 41113843)
-
(2005)
Journal of Immunology
, vol.175
, Issue.4
, pp. 2340-2348
-
-
Akiba, H.1
Takeda, K.2
Kojima, Y.3
Usui, Y.4
Harada, N.5
Yamazaki, T.6
Ma, J.7
Tezuka, K.8
Yagita, H.9
Okumura, K.10
-
15
-
-
0030582773
-
A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen
-
DOI 10.1016/S0092-8674(00)81798-5
-
Förster R, et al. (1996) A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 87:1037-1047. (Pubitemid 26427987)
-
(1996)
Cell
, vol.87
, Issue.6
, pp. 1037-1047
-
-
Forster, R.1
Mattis, A.E.2
Kremmer, E.3
Wolf, E.4
Brem, G.5
Lipp, M.6
-
16
-
-
38049144850
-
Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation
-
Haynes NM, et al. (2007) Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulation. J Immunol 179:5099-5108.
-
(2007)
J Immunol
, vol.179
, pp. 5099-5108
-
-
Haynes, N.M.1
-
17
-
-
13444283466
-
Roles of interferon-regulatory factors in T-helper-cell differentiation
-
DOI 10.1038/nri1552
-
Lohoff M, Mak TW (2005) Roles of interferon-regulatory factors in T-helper-cell differentiation. Nat Rev Immunol 5:125-135. (Pubitemid 40208902)
-
(2005)
Nature Reviews Immunology
, vol.5
, Issue.2
, pp. 125-135
-
-
Lohoff, M.1
Mak, T.W.2
-
18
-
-
0030747793
-
Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo
-
DOI 10.1016/S1074-7613(00)80444-6
-
Lohoff M, et al. (1997) Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo. Immunity 6:681-689. (Pubitemid 27305731)
-
(1997)
Immunity
, vol.6
, Issue.6
, pp. 681-689
-
-
Lohoff, M.1
Ferrick, D.2
Mittrucker, H.-W.3
Duncan, G.S.4
Bischof, S.5
Rollinghoff, M.6
Mak, T.W.7
-
19
-
-
0030741433
-
Multistage regulation of Th1-type immune responses by the transcription factor IRF-1
-
DOI 10.1016/S1074-7613(00)80443-4
-
Taki S, et al. (1997) Multistage regulation of Th1-type immune responses by the transcription factor IRF-1. Immunity 6:673-679. (Pubitemid 27305730)
-
(1997)
Immunity
, vol.6
, Issue.6
, pp. 673-679
-
-
Taki, S.1
Sato, T.2
Ogasawara, K.3
Fukuda, T.4
Sato, M.5
Hida, S.6
Suzuki, G.7
Mitsuyama, M.8
Shin, E.-H.9
Kojima, S.10
Taniguchi, T.11
Asano, Y.12
-
20
-
-
34548128307
-
H-17 cells requires interferon-regulatory factor 4
-
DOI 10.1038/ni1500, PII NI1500
-
Brüstle A, et al. (2007) The development of inflammatory T(H)-17 cells requires interferon- regulatory factor 4. Nat Immunol 8:958-966. (Pubitemid 47300010)
-
(2007)
Nature Immunology
, vol.8
, Issue.9
, pp. 958-966
-
-
Brustle, A.1
Heink, S.2
Huber, M.3
Rosenplanter, C.4
Stadelmann, C.5
Yu, P.6
Arpaia, E.7
Mak, T.W.8
Kamradt, T.9
Lohoff, M.10
-
21
-
-
58549094107
-
IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype
-
Huber M, et al. (2008) IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype. Proc Natl Acad Sci USA 105:20846-20851.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20846-20851
-
-
Huber, M.1
-
22
-
-
0037015052
-
Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4
-
DOI 10.1073/pnas.182425099
-
Lohoff M, et al. (2002) Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4. Proc Natl Acad Sci USA 99:11808-11812. (Pubitemid 34994480)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.18
, pp. 11808-11812
-
-
Lohoff, M.1
Mittrucker, H.-W.2
Prechtl, S.3
Bischof, S.4
Sommer, F.5
Kock, S.6
Ferrick, D.A.7
Duncan, G.S.8
Gessner, A.9
Mak, T.W.10
-
23
-
-
0037089575
-
Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression
-
DOI 10.1084/jem.20011128
-
Rengarajan J, et al. (2002) Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression. J Exp Med 195:1003-1012. (Pubitemid 34412002)
-
(2002)
Journal of Experimental Medicine
, vol.195
, Issue.8
, pp. 1003-1012
-
-
Rengarajan, J.1
Mowen, K.A.2
McBride, K.D.3
Smith, E.D.4
Singh, H.5
Glimcher, L.H.6
-
24
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
DOI 10.1084/jem.20041257
-
Langrish CL, et al. (2005) IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 201:233-240. (Pubitemid 40189432)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.2
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
McClanahan, T.7
Kastelein, R.A.8
Cua, D.J.9
-
25
-
-
62649165369
-
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses
-
Zheng Y, et al. (2009) Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses. Nature 458:351-356.
-
(2009)
Nature
, vol.458
, pp. 351-356
-
-
Zheng, Y.1
-
26
-
-
57449105853
-
IRF-4-binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor
-
Chen Q, et al. (2008) IRF-4-binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor. Immunity 29: 899-911.
-
(2008)
Immunity
, vol.29
, pp. 899-911
-
-
Chen, Q.1
-
27
-
-
77955902281
-
Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells
-
Staudt V, et al. (2010) Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells. Immunity 33:192-202.
-
(2010)
Immunity
, vol.33
, pp. 192-202
-
-
Staudt, V.1
-
28
-
-
33745182931
-
Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination
-
DOI 10.1038/ni1357, PII N1357
-
Klein U, et al. (2006) Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination. Nat Immunol 7:773-782. (Pubitemid 43905877)
-
(2006)
Nature Immunology
, vol.7
, Issue.7
, pp. 773-782
-
-
Klein, U.1
Casola, S.2
Cattoretti, G.3
Shen, Q.4
Lia, M.5
Mo, T.6
Ludwig, T.7
Rajewsky, K.8
Dalla-Favera, R.9
-
29
-
-
33747133955
-
Graded Expression of Interferon Regulatory Factor-4 Coordinates Isotype Switching with Plasma Cell Differentiation
-
DOI 10.1016/j.immuni.2006.07.009, PII S1074761306003517
-
Sciammas R, et al. (2006) Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation. Immunity 25:225-236. (Pubitemid 44224149)
-
(2006)
Immunity
, vol.25
, Issue.2
, pp. 225-236
-
-
Sciammas, R.1
Shaffer, A.L.2
Schatz, J.H.3
Zhao, H.4
Staudt, L.M.5
Singh, H.6
-
30
-
-
0023679729
-
Polyclonal B-cell stimulation by L3T4+ T cells in experimental leishmaniasis
-
Lohoff M, Matzner C, Röllinghoff M (1988) Polyclonal B-cell stimulation by L3T4+ T cells in experimental leishmaniasis. Infect Immun 56:2120-2124.
-
(1988)
Infect Immun
, vol.56
, pp. 2120-2124
-
-
Lohoff, M.1
Matzner, C.2
Röllinghoff, M.3
-
31
-
-
0029062080
-
Regulation of germinal center B cell differentiation. Role of the human APO-1/Fas (CD95) molecule
-
Lagresle C, Bella C, Daniel PT, Krammer PH, Defrance T (1995) Regulation of germinal center B cell differentiation. Role of the human APO-1/Fas (CD95) molecule. J Immunol 154:5746-5756.
-
(1995)
J Immunol
, vol.154
, pp. 5746-5756
-
-
Lagresle, C.1
Bella, C.2
Daniel, P.T.3
Krammer, P.H.4
Defrance, T.5
-
32
-
-
0027324869
-
Characterization of a novel cell-surface molecule expressed on subpopulations of activated T and B cells
-
Laszlo G, Hathcock KS, Dickler HB, Hodes RJ (1993) Characterization of a novel cell-surface molecule expressed on subpopulations of activated T and B cells. J Immunol 150:5252-5262. (Pubitemid 23180638)
-
(1993)
Journal of Immunology
, vol.150
, Issue.12
, pp. 5252-5262
-
-
Laszlo, G.1
Hathcock, K.S.2
Dickler, H.B.3
Hodes, R.J.4
-
33
-
-
45949106108
-
Down-regulation of ICOS ligand by interaction with ICOS functions as a regulatory mechanism for immune responses
-
Watanabe M, et al. (2008) Down-regulation of ICOS ligand by interaction with ICOS functions as a regulatory mechanism for immune responses. J Immunol 180: 5222-5234.
-
(2008)
J Immunol
, vol.180
, pp. 5222-5234
-
-
Watanabe, M.1
-
34
-
-
3242759829
-
+ Th cells
-
DOI 10.1084/jem.20040182
-
Lohoff M, et al. (2004) Enhanced TCR-induced apoptosis in interferon regulatory factor 4-deficient CD4(+) Th cells. J Exp Med 200:247-253. (Pubitemid 38982183)
-
(2004)
Journal of Experimental Medicine
, vol.200
, Issue.2
, pp. 247-253
-
-
Lohoff, M.1
Mittrucker, H.-W.2
Brustle, A.3
Sommer, F.4
Casper, B.5
Huber, M.6
Ferrick, D.A.7
Duncan, G.S.8
Mak, T.W.9
-
35
-
-
15444346834
-
Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function
-
Mittrücker HW, et al. (1997) Requirement for the transcription factor LSIRF/IRF4 for mature B and T lymphocyte function. Science 275:540-543.
-
(1997)
Science
, vol.275
, pp. 540-543
-
-
Mittrücker, H.W.1
-
36
-
-
58449124804
-
The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
-
Bauquet AT, et al. (2009) The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells. Nat Immunol 10:167-175.
-
(2009)
Nat Immunol
, vol.10
, pp. 167-175
-
-
Bauquet, A.T.1
-
37
-
-
71749089605
-
Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors
-
Kwon H, et al. (2009) Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors. Immunity 31: 941-952.
-
(2009)
Immunity
, vol.31
, pp. 941-952
-
-
Kwon, H.1
-
38
-
-
34548237299
-
A Signaling Pathway Mediating Downregulation of BCL6 in Germinal Center B Cells Is Blocked by BCL6 Gene Alterations in B Cell Lymphoma
-
DOI 10.1016/j.ccr.2007.08.011, PII S153561080700236X
-
Saito M, et al. (2007) A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma. Cancer Cell 12:280-292. (Pubitemid 47333420)
-
(2007)
Cancer Cell
, vol.12
, Issue.3
, pp. 280-292
-
-
Saito, M.1
Gao, J.2
Basso, K.3
Kitagawa, Y.4
Smith, P.M.5
Bhagat, G.6
Pernis, A.7
Pasqualucci, L.8
Dalla-Favera, R.9
-
39
-
-
0033400453
-
Lineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4
-
DOI 10.1084/jem.190.12.1837
-
Gupta S, Jiang M, Anthony A, Pernis AB (1999) Lineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4. J Exp Med 190:1837-1848. (Pubitemid 30013849)
-
(1999)
Journal of Experimental Medicine
, vol.190
, Issue.12
, pp. 1837-1848
-
-
Gupta, S.1
Jiang, M.2
Anthony, A.3
Pernis, A.B.4
|