IFN consensus sequence binding protein (Icsbp) is critical for eosinophil development

Journal of Immunology

Volumn 181, Issue 7, 2008, Pages 5045-5053

  Milanovic, Maja ^a   Terszowski, Grzegorz ^b   Struck, Daniela ^c   Liesenfeld, Oliver ^c   Carstanjen, Dirk ^a  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^b UNIVERSITY OF ULM   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERLEUKIN 5; TRANSCRIPTION FACTOR GATA 1; INTERFERON REGULATORY FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL MATURATION; CONTROLLED STUDY; EOSINOPHIL; EOSINOPHILIA; GENE EXPRESSION; IMMUNE RESPONSE; MOUSE; NEMATODE; NIPPOSTRONGYLUS BRASILIENSIS; NONHUMAN; PARASITOSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; REGULATORY MECHANISM; STEM CELL; WILD TYPE; ANIMAL; C57BL MOUSE; CELL CULTURE; CONSENSUS SEQUENCE; GENETIC TRANSCRIPTION; GENETICS; IMMUNOLOGY; LEUKOCYTE COUNT; LEWIS RAT; METABOLISM; MOUSE MUTANT; NIPPOSTRONGYLUS; PARASITOLOGY; PATHOLOGY; PHYSIOLOGY; RAT; STRONGYLE INFECTION;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; CONSENSUS SEQUENCE; EOSINOPHILIA; EOSINOPHILS; INTERFERON REGULATORY FACTORS; LEUKOCYTE COUNT; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NIPPOSTRONGYLUS; RATS; RATS, INBRED LEW; STRONGYLIDA INFECTIONS; TRANSCRIPTION, GENETIC;

EID: 58149311492     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.7.5045     Document Type: Article

References (47)

1. Rothenberg, M. E. 1998. Eosinophilia. N. Engl. J. Med. 338: 1592-1600.
2. Rothenberg, M. E., and S. P. Hogan. 2006. The eosinophil. Annu. Rev. Immunol. 24: 147-174.
3. Humbles, A. A., C. M. Lloyd, S. J. McMillan, D. S. Friend, G. Xanthou, E. E. McKenna, S. Ghiran, N. P. Gerard, C. Yu, S. H. Orkin, and C. Gerard. 2004. A critical role for eosinophils in allergic airways remodeling. Science 305: 1776-1779. (Pubitemid 39249645)
4. Lee, J. J., D. Dimina, M. P. Macias, S. I. Ochkur, M. P. McGarry, K. R. O'Neill, C. Protheroe, R. Pero, T. Nguyen, S. A. Cormier, et al. 2004. Defining a link with asthma in mice congenitally deficient in eosinophils. Science 305: 1773-1776.
5. Iwasaki, H., S. Mizuno, R. Mayfield, H. Shigematsu, Y. Arinobu, B. Seed, M. F. Gurish, K. Takatsu, and K. Akashi. 2005. Identification of eosinophil lineage- committed progenitors in the murine bone marrow. J. Exp. Med. 201: 1891-1897. (Pubitemid 41002925)
6. Yu, C., A. B. Cantor, H. Yang, C. Browne, R. A. Wells, Y. Fujiwara, and S. H. Orkin. 2002. Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo. J. Exp. Med. 195: 1387-1395. (Pubitemid 34602816)
7. Yamaguchi, Y., H. Nishio, K. Kishi, S. J. Ackerman, and T. Suda. 1999. C/EBPβ and GATA-1 synergistically regulate activity of the eosinophil granule major basic protein promoter: implication for C/EBPβ activity in eosinophil gene expression. Blood 94: 1429-1439. (Pubitemid 29380424)
8. Zhang, D. E., P. Zhang, N. D. Wang, C. J. Hetherington, G. J. Darlington, and D. G. Tenen. 1997. Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice. Proc. Natl. Acad. Sci. USA 94: 569-574.
9. Nerlov, C., K. M. McNagny, G. Doderlein, E. Kowenz-Leutz, and T. Graf. 1998. Distinct C/EBP functions are required for eosinophil lineage commitment and maturation. Genes Dev. 12: 2413-2423. (Pubitemid 28371360)
10. Yamanaka, R., G. D. Kim, H. S. Radomska, J. Lekstrom-Himes, L. T. Smith, P. Antonson, D. G. Tenen, and K. G. Xanthopoulos. 1997. CCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing. Proc. Natl. Acad. Sci. USA 94: 6462-6467. (Pubitemid 27270707)
11. Du, J., M. J. Stankiewicz, Y. Liu, Q. Xi, J. E. Schmitz, J. A. Lekstrom-Himes, and S. J. Ackerman. 2002. Novel combinatorial interactions of GATA-1, PU. 1, and C/EBPε isoforms regulate transcription of the gene encoding eosinophil granule major basic protein. J. Biol. Chem. 277: 43481-43494. (Pubitemid 35285737)
12. Driggers, P. H., D. L. Ennist, S. L. Gleason, W. H. Mak, M. S. Marks, B. Z. Levi, J. R. Flanagan, E. Appella, and K. Ozato. 1990. An interferon gamma-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes. Proc. Natl. Acad. Sci. USA 87: 3743-3747. (Pubitemid 20182535)
13. Weisz, A., P. Marx, R. Sharf, E. Appella, P. H. Driggers, K. Ozato, and B. Z. Levi. 1992. Human interferon consensus sequence binding protein is a negative regulator of enhancer elements common to interferon-inducible genes. J. Biol. Chem. 267: 25589-25596.
14. Nguyen, H., J. Hiscott, and P. M. Pitha. 1997. The growing family of interferon regulatory factors. Cytokine Growth Factor Rev. 8: 293-312. (Pubitemid 28201655)
15. Eisenbeis, C. F., H. Singh, and U. Storb. 1995. Pip, a novel IRF family member, is a lymphoid-specific, PU. 1-dependent transcriptional activator. Genes Dev. 9: 1377-1387.
16. Escalante, C. R., A. L. Brass, J. M. Pongubala, E. Shatova, L. Shen, H. Singh, and A. K. Aggarwal. 2002. Crystal structure of PU. 1/IRF-4/DNA ternary complex. Mol. Cell. 10: 1097-1105. (Pubitemid 35453827)
17. Holtschke, T., J. Lohler, Y. Kanno, T. Fehr, N. Giese, F. Rosenbauer, J. Lou, K. P. Knobeloch, L. Gabriele, J. F. Waring, et al. 1996. Immunodeficiency and chronic myelogenous leukemia-like syndrome in mice with a targeted mutation of the ICSBP gene. Cell 87: 307-317. (Pubitemid 26359008)
18. Fehr, T., G. Schoedon, B. Odermatt, T. Holtschke, M. Schneemann, M. F. Bachmann, T. W. Mak, I. Horak, and R. M. Zinkernagel. 1997. Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis. J. Exp. Med. 185: 921-931. (Pubitemid 27119876)
19. Scharton-Kersten, T., C. Contursi, A. Masumi, A. Sher, and K. Ozato. 1997. Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction. J. Exp. Med. 186: 1523-1534. (Pubitemid 27479812)
20. Terszowski, G., C. Waskow, P. Conradt, D. Lenze, J. Koenigsmann, D. Carstanjen, I. Horak, and H. R. Rodewald. 2005. Prospective isolation and global gene expression analysis of the erythrocyte colony-forming unit (CFU-E). Blood. 105: 1937-1945. (Pubitemid 40731775)
21. Karasuyama, H., and F. Melchers. 1988. Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors. Eur. J. Immunol. 18: 97-104. (Pubitemid 18072702)
22. Louahed, J., Y. Zhou, W. L. Maloy, P. U. Rani, C. Weiss, Y. Tomer, A. Vink, J. Renauld, J. Van Snick, N. C. Nicolaides, et al. 2001. Interleukin 9 promotes influx and local maturation of eosinophils. Blood 97: 1035-1042. (Pubitemid 32154290)
23. Yamaguchi, Y., T. Suda, J. Suda, M. Eguchi, Y. Miura, N. Harada, A. Tominaga, and K. Takatsu. 1988. Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors. J. Exp. Med. 167: 43-56. (Pubitemid 18093692)
24. Dent, L. A., M. Strath, A. L. Mellor, and C. J. Sanderson. 1990. Eosinophilia in transgenic mice expressing interleukin 5. J. Exp. Med. 172: 1425-1431.
25. + B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses. Immunity 4: 15-24.
26. Masumi, A., S. Tamaoki, I. M. Wang, K. Ozato, and K. Komuro. 2002. IRF-8/ICSBP and IRF-1 cooperatively stimulate mouse IL-12 promoter activity in macrophages. FEBS Lett. 531: 348-353. (Pubitemid 35341222)
27. Wu, C. Y., H. Maeda, C. Contursi, K. Ozato, and R. A. Seder. 1999. Differential requirement of IFN consensus sequence binding protein for the production of IL-12 and induction of Th1-type cells in response to IFN-γ. J. Immunol. 162: 807-812.
28. Scheller, M., J. Foerster, C. M. Heyworth, J. F. Waring, J. Lohler, G. L. Gilmore, R. K. Shadduck, T. M. Dexter, and I. Horak. 1999. Altered development and cytokine responses of myeloid progenitors in the absence of transcription factor, interferon consensus sequence binding protein. Blood 94: 3764-3771.
29. Guthridge, M. A., F. C. Stomski, D. Thomas, J. M. Woodcock, C. J. Bagley, M. C. Berndt, and A. F. Lopez. 1998. Mechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors. Stem Cells 16: 301-313.
30. McGarry, M. P., and C. C. Stewart. 1991. Murine eosinophil granulocytes bind the murine macrophage-monocyte specific monoclonal antibody F4/80. J. Leukocyte Biol. 50: 471-478.
31. Shivdasani, R. A., and S. H. Orkin. 1996. The transcriptional control of hematopoiesis. Blood 87: 4025-4039.
32. Fujiwara, Y., C. P. Browne, K. Cunniff, S. C. Goff, and S. H. Orkin. 1996. Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1. Proc. Natl. Acad. Sci. USA 93: 12355-12358. (Pubitemid 26367147)
33. Shivdasani, R. A., Y. Fujiwara, M. A. McDevitt, and S. H. Orkin. 1997. A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development. EMBO J. 16: 3965-3973.
34. Ma, S., S. Pathak, L. Trinh, and R. Lu. 2008. Interferon regulatory factors 4 and 8 induce the expression of Ikaros and Aiolos to down-regulate pre-B-cell receptor and promote cell-cycle withdrawal in pre-B-cell development. Blood 111: 1396-1403.
35. Tamura, T., T. Nagamura-Inoue, Z. Shmeltzer, T. Kuwata, and K. Ozato. 2000. ICSBP directs bipotential myeloid progenitor cells to differentiate into mature macrophages. Immunity 13: 155-165. (Pubitemid 30951882)
36. Lu, R., K. L. Medina, D. W. Lancki, and H. Singh. 2003. IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development. Genes Dev. 17: 1703-1708. (Pubitemid 36870333)
37. Klion, A. D., and T. B. Nutman. 2004. The role of eosinophils in host defense against helminth parasites. J. Allergy Clin. Immunol. 113: 30-37. (Pubitemid 38096158)
38. Tsujimura, H., T. Nagamura-Inoue, T. Tamura, and K. Ozato. 2002. IFN consensus sequence binding protein/IFN regulatory factor-8 guides bone marrow progenitor cells toward the macrophage lineage. J. Immunol. 169: 1261-1269. (Pubitemid 34809167)
39. Tsujimura, H., T. Tamura, and K. Ozato. 2003. Cutting edge: IFN consensus sequence binding protein/IFN regulatory factor 8 drives the development of type I IFN-producing plasmacytoid dendritic cells. J. Immunol. 170: 1131-1135. (Pubitemid 36139475)
40. + dendritic cells. Blood 101: 305-310.
41. Yoshida, T., K. Ikuta, H. Sugaya, K. Maki, M. Takagi, H. Kanazawa, S. Sunaga, T. Kinashi, K. Yoshimura, J. Miyazaki, et al. 1996. Defective B-1 cell development and impaired immunity against Angiostrongylus cantonensis in IL-5R α-deficient mice. Immunity 4: 483-494. (Pubitemid 26354657)
42. Hirasawa, R., R. Shimizu, S. Takahashi, M. Osawa, S. Takayanagi, Y. Kato, M. Onodera, N. Minegishi, M. Yamamoto, K. Fukao, et al. 2002. Essential and instructive roles of GATA factors in eosinophil development. J. Exp. Med. 195: 1379-1386. (Pubitemid 34602815)
43. Kulessa, H., J. Frampton, and T. Graf. 1995. GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts. Genes Dev. 9: 1250-1262.
44. McNagny, K., and T. Graf. 2002. Making eosinophils through subtle shifts in transcription factor expression. J. Exp. Med. 195: F43-F47. (Pubitemid 34602814)
45. Rosenbauer, F., K. Wagner, J. L. Kutok, H. Iwasaki, M. M. Le Beau, Y. Okuno, K. Akashi, S. Fiering, and D. G. Tenen. 2004. Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU. 1. Nat. Genet. 36: 624-630. (Pubitemid 38715991)
46. Guyot, B., V. Valverde-Garduno, C. Porcher, and P. Vyas. 2004. Deletion of the major GATA1 enhancer HS 1 does not affect eosinophil GATA1 expression and eosinophil differentiation. Blood 104: 89-91. (Pubitemid 38879842)
47. Williams, S. C., Y. Du, R. C. Schwartz, S. R. Weiler, M. Ortiz, J. R. Keller, and P. F. Johnson. 1998. C/EBPε is a myeloid-specific activator of cytokine, chemokine, and macrophage-colony-stimulating factor receptor genes. J. Biol. Chem. 273: 13493-13501.