Activation of the NLRP3 inflammasome complex is not required for stress-induced death of pancreatic islets

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Wali, Jibran A ^a,b   Gurzov, Esteban N ^a,b   Fynch, Stacey ^a   Elkerbout, Lorraine ^a   Kay, Thomas W ^a,b   Masters, Seth L ^c   Thomas, Helen E ^a,b  

^a ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; CXCL1 CHEMOKINE; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; PRIMER DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL STRESS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DNA FRAGMENTATION; ENDOPLASMIC RETICULUM STRESS; GENE ACTIVATION; GENE INACTIVATION; GLUCOTOXICITY; IN VITRO STUDY; LIPOTOXICITY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; PROTEIN CLEAVAGE; PROTEIN FUNCTION; WILD TYPE; ANALYSIS OF VARIANCE; ANIMAL; APOPTOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; GENOTYPE; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET; PATHOPHYSIOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CARRIER PROTEINS; DIABETES MELLITUS, TYPE 2; DNA PRIMERS; ENDOPLASMIC RETICULUM STRESS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENOTYPE; ISLETS OF LANGERHANS; MICE; POLYMERASE CHAIN REACTION;

EID: 84915782617     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0113128     Document Type: Article

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