Involvement of chronic stresses in rat islet and INS-1 cell glucotoxicity induced by intermittent high glucose

Molecular and Cellular Endocrinology

Volumn 291, Issue 1-2, 2008, Pages 71-78

  Hou, Zhi Qiang ^a,b   Li, Hong Liang ^b   Gao, Ling ^a   Pan, Lin ^b   Zhao, Jia Jun ^a   Li, Guang Wei ^b  

^a SHANDONG UNIVERSITY   (China)

^b CHINA JAPAN FRIENDSHIP HOSPITAL   (China)

Author keywords

Endoplasmic reticulum stress; Glucotoxicity; INS 1 cell; Intermittent high glucose; Oxidative stress; Rat pancreatic islet

Indexed keywords

GLUCOSE; INSULIN;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CELL ISOLATION; CELL STRESS; CELL VIABILITY; CHRONIC STRESS; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM; GENE EXPRESSION; INSULIN RELEASE; MALE; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; CELL SURVIVAL; CELLS, CULTURED; DEOXYGUANOSINE; EIF-2 KINASE; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; EUKARYOTIC INITIATION FACTOR-2; GLUCOSE; INSULIN-SECRETING CELLS; MALE; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STRESS, PSYCHOLOGICAL; TRANSCRIPTION FACTOR CHOP; TYROSINE;

EID: 48349133849     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2008.03.004     Document Type: Article

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