High-fat-fed obese glutathione peroxidase 1-deficient mice exhibit defective insulin secretion but protection from hepatic steatosis and liver damage

Antioxidants and Redox Signaling

Volumn 20, Issue 14, 2014, Pages 2114-2129

  Merry, Troy L ^a   Tran, Melanie ^a   Stathopoulos, Maria ^b   Wiede, Florian ^a   Fam, Barbara Christianne ^b   Dodd, Garron T ^a   Clarke, Iain ^a   Watt, Matthew J ^a   Andrikopoulos, Sofianos ^b   Tiganis, Tony ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLUTATHIONE PEROXIDASE 1; HYDROGEN PEROXIDE; INSULIN; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 2; PROTEIN TYROSINE PHOSPHATASE; REACTIVE OXYGEN METABOLITE; STAT1 PROTEIN; TRANSCRIPTION FACTOR PDX 1; GLUCOSE BLOOD LEVEL; GLUTATHIONE PEROXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INACTIVATION; FATTY LIVER; GLUCONEOGENESIS; GLUCOSE HOMEOSTASIS; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; LIPOGENESIS; LIVER INJURY; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; OBESITY; OXIDATION; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; BLOOD; C57BL MOUSE; CYTOLOGY; DEFICIENCY; GLUCOSE BLOOD LEVEL; KNOCKOUT MOUSE; LIVER; METABOLISM; MOUSE MUTANT; PATHOLOGY; SECRETION (PROCESS);

ANIMALS; BLOOD GLUCOSE; DIET, HIGH-FAT; FATTY LIVER; GLUTATHIONE PEROXIDASE; HYPERGLYCEMIA; INSULIN; LIVER; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, OBESE; OBESITY; OXIDATIVE STRESS;

EID: 84894278759     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2013.5428     Document Type: Article

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