-
1
-
-
80053442677
-
Fluorescent microangiography is a novel and widely applicable technique for delineating the renal microvasculature
-
Advani A, Connelly KA, Yuen DA, Zhang Y, Advani SL, Trogadis J, Kabir MG, Shachar E, Kuliszewski MA, Leong-Poi H, Stewart DJ, Gilbert RE. Fluorescent microangiography is a novel and widely applicable technique for delineating the renal microvasculature. PLoS One 6: e24695, 2011.
-
(2011)
Plos One
, vol.6
-
-
Advani, A.1
Connelly, K.A.2
Yuen, D.A.3
Zhang, Y.4
Advani, S.L.5
Trogadis, J.6
Kabir, M.G.7
Shachar, E.8
Kuliszewski, M.A.9
Leong-Poi, H.10
Stewart, D.J.11
Gilbert, R.E.12
-
2
-
-
70350680440
-
Outcomes following diagnosis of acute renal failure in U.S veterans: Focus on acute tubular necrosis
-
Amdur RL, Chawla LS, Amodeo S, Kimmel PL, Palant CE. Outcomes following diagnosis of acute renal failure in U.S veterans: focus on acute tubular necrosis. Kidney Int 76: 1089–1097, 2009.
-
(2009)
Kidney Int
, vol.76
, pp. 1089-1097
-
-
Amdur, R.L.1
Chawla, L.S.2
Amodeo, S.3
Kimmel, P.L.4
Palant, C.E.5
-
3
-
-
80053394522
-
Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice
-
Asada N, Takase M, Nakamura J, Oguchi A, Asada M, Suzuki N, Yamamura K, Nagoshi N, Shibata S, Rao TN, Fehling HJ, Fukatsu A, Minegishi N, Kita T, Kimura T, Okano H, Yamamoto M, Yanagita M. Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice. J Clin Invest 121: 3981–3990, 2011.
-
(2011)
J Clin Invest
, vol.121
, pp. 3981-3990
-
-
Asada, N.1
Takase, M.2
Nakamura, J.3
Oguchi, A.4
Asada, M.5
Suzuki, N.6
Yamamura, K.7
Nagoshi, N.8
Shibata, S.9
Rao, T.N.10
Fehling, H.J.11
Fukatsu, A.12
Minegishi, N.13
Kita, T.14
Kimura, T.15
Okano, H.16
Yamamoto, M.17
Yanagita, M.18
-
4
-
-
60749095669
-
Renal ischemia-reperfusion leads to long term infiltration of activated and effector-memory T lymphocytes
-
Ascon M, Ascon DB, Liu M, Cheadle C, Sarkar C, Racusen L, Hassoun HT, Rabb H. Renal ischemia-reperfusion leads to long term infiltration of activated and effector-memory T lymphocytes. Kidney Int 75: 526–535, 2009.
-
(2009)
Kidney Int
, vol.75
, pp. 526-535
-
-
Ascon, M.1
Ascon, D.B.2
Liu, M.3
Cheadle, C.4
Sarkar, C.5
Racusen, L.6
Hassoun, H.T.7
Rabb, H.8
-
5
-
-
30944437447
-
3–5 year longitudinal follow-up of pediatric patients after acute renal failure
-
Askenazi DJ, Feig DI, Graham NM, Hui-Stickle S, Goldstein SL. 3–5 year longitudinal follow-up of pediatric patients after acute renal failure. Kidney Int 69: 184–189, 2006.
-
(2006)
Kidney Int
, vol.69
, pp. 184-189
-
-
Askenazi, D.J.1
Feig, D.I.2
Graham, N.M.3
Hui-Stickle, S.4
Goldstein, S.L.5
-
6
-
-
34447526131
-
The endothelial cell in ischemic acute kidney injury: Implications for acute and chronic function
-
Basile DP. The endothelial cell in ischemic acute kidney injury: implications for acute and chronic function. Kidney Int 72: 151–156, 2007.
-
(2007)
Kidney Int
, vol.72
, pp. 151-156
-
-
Basile, D.P.1
-
8
-
-
0035199934
-
Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-term function
-
Basile DP, Donohoe D, Roethe K, Osborn JL. Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-term function. Am J Physiol Renal Physiol 281: F887–F899, 2001.
-
(2001)
Am J Physiol Renal Physiol
, vol.281
, pp. F887-F899
-
-
Basile, D.P.1
Donohoe, D.2
Roethe, K.3
Osborn, J.L.4
-
9
-
-
0037303729
-
Chronic renal hypoxia after acute ischemic injury: Effects of L-arginine on hypoxia and secondary damage
-
Basile DP, Donohoe DL, Roethe K, Mattson DL. Chronic renal hypoxia after acute ischemic injury: effects of L-arginine on hypoxia and secondary damage. Am J Physiol Renal Physiol 284: F338–F348, 2003.
-
(2003)
Am J Physiol Renal Physiol
, vol.284
, pp. F338-F348
-
-
Basile, D.P.1
Donohoe, D.L.2
Roethe, K.3
Mattson, D.L.4
-
10
-
-
44949200310
-
Renal ischemia reperfusion inhibits VEGF expression and induces AD-AMTS-1, a novel VEGF inhibitor
-
Basile DP, Fredrich K, Chelladurai B, Leonard EC, Parrish AR. Renal ischemia reperfusion inhibits VEGF expression and induces AD-AMTS-1, a novel VEGF inhibitor. Am J Physiol Renal Physiol 294: F928–F936, 2008.
-
(2008)
Am J Physiol Renal Physiol
, vol.294
, pp. F928-F936
-
-
Basile, D.P.1
Fredrich, K.2
Chelladurai, B.3
Leonard, E.C.4
Parrish, A.R.5
-
11
-
-
79953196750
-
Impaired endothelial proliferation and mesenchymal transition contribute to vascular rarefaction following acute kidney injury
-
Basile DP, Friedrich JL, Spahic J, Knipe N, Mang H, Leonard EC, Changizi-Ashtiyani S, Bacallao RL, Molitoris BA, Sutton TA. Impaired endothelial proliferation and mesenchymal transition contribute to vascular rarefaction following acute kidney injury. Am J Physiol Renal Physiol 300: F721–F733, 2011.
-
(2011)
Am J Physiol Renal Physiol
, vol.300
, pp. F721-F733
-
-
Basile, D.P.1
Friedrich, J.L.2
Spahic, J.3
Knipe, N.4
Mang, H.5
Leonard, E.C.6
Changizi-Ashtiyani, S.7
Bacallao, R.L.8
Molitoris, B.A.9
Sutton, T.A.10
-
12
-
-
77952116121
-
Methylation determines fibroblast activation and fibrogenesis in the kidney
-
Bechtel W, McGoohan S, Zeisberg EM, Müller GA, Kalbacher H, Salant DJ, Müller CA, Kalluri R, Zeisberg M. Methylation determines fibroblast activation and fibrogenesis in the kidney. Nat Med 16: 544–550, 2010.
-
(2010)
Nat Med
, vol.16
, pp. 544-550
-
-
Bechtel, W.1
McGoohan, S.2
Zeisberg, E.M.3
Müller, G.A.4
Kalbacher, H.5
Salant, D.J.6
Müller, C.A.7
Kalluri, R.8
Zeisberg, M.9
-
13
-
-
84894060402
-
The link between acute kidney injury and chronic kidney disease
-
Belayev LY, Palevsky PM. The link between acute kidney injury and chronic kidney disease. Curr Opin Nephrol Hypertens 23: 149–154, 2014.
-
(2014)
Curr Opin Nephrol Hypertens
, vol.23
, pp. 149-154
-
-
Belayev, L.Y.1
Palevsky, P.M.2
-
14
-
-
33745820018
-
Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure
-
Bernhardt WM, Câmpean V, Kany S, Jürgensen JS, Weidemann A, Warnecke C, Arend M, Klaus S, Günzler V, Amann K, Willam C, Wiesener MS, Eckardt KU. Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure. J Am Soc Nephrol 17: 1970–1978, 2006.
-
(2006)
J am Soc Nephrol
, vol.17
, pp. 1970-1978
-
-
Bernhardt, W.M.1
Câmpean, V.2
Kany, S.3
Jürgensen, J.S.4
Weidemann, A.5
Warnecke, C.6
Arend, M.7
Klaus, S.8
Günzler, V.9
Amann, K.10
Willam, C.11
Wiesener, M.S.12
Eckardt, K.U.13
-
15
-
-
80555157523
-
Cellular pathophysiology of ischemic acute kidney injury
-
Bonventre JV, Yang L. Cellular pathophysiology of ischemic acute kidney injury. J Clin Invest 121: 4210–4221, 2011.
-
(2011)
J Clin Invest
, vol.121
, pp. 4210-4221
-
-
Bonventre, J.V.1
Yang, L.2
-
17
-
-
0029640011
-
Hypoxia of the renal medulla–its implications for disease
-
Brezis M, Rosen S. Hypoxia of the renal medulla–its implications for disease. N Engl J Med 332: 647–655, 1995.
-
(1995)
N Engl J Med
, vol.332
, pp. 647-655
-
-
Brezis, M.1
Rosen, S.2
-
18
-
-
0026487867
-
Vascular permeability factor mRNA and protein expression in human kidney
-
Brown LF, Berse B, Tognazzi K, Manseau EJ, Van de Water L, Senger DR, Dvorak HF, Rosen S. Vascular permeability factor mRNA and protein expression in human kidney. Kidney Int 42: 1457–1461, 1992.
-
(1992)
Kidney Int
, vol.42
, pp. 1457-1461
-
-
Brown, L.F.1
Berse, B.2
Tognazzi, K.3
Manseau, E.J.4
Van De Water, L.5
Senger, D.R.6
Dvorak, H.F.7
Rosen, S.8
-
19
-
-
84857082981
-
Increased risk of death and de novo chronic kidney disease following reversible acute kidney injury
-
Bucaloiu ID, Kirchner HL, Norfolk ER, Hartle JE, Perkins RM. Increased risk of death and de novo chronic kidney disease following reversible acute kidney injury. Kidney Int 81: 477–485, 2012.
-
(2012)
Kidney Int
, vol.81
, pp. 477-485
-
-
Bucaloiu, I.D.1
Kirchner, H.L.2
Norfolk, E.R.3
Hartle, J.E.4
Perkins, R.M.5
-
20
-
-
20844462254
-
Persistent renal and extrarenal immune changes after severe ischemic injury
-
Burne-Taney MJ, Yokota N, Rabb H. Persistent renal and extrarenal immune changes after severe ischemic injury. Kidney Int 67: 1002–1009, 2005.
-
(2005)
Kidney Int
, vol.67
, pp. 1002-1009
-
-
Burne-Taney, M.J.1
Yokota, N.2
Rabb, H.3
-
21
-
-
79957821845
-
The severity of acute kidney injury predicts progression to chronic kidney disease
-
Chawla LS, Amdur RL, Amodeo S, Kimmel PL, Palant CE. The severity of acute kidney injury predicts progression to chronic kidney disease. Kidney Int 79: 1361–1369, 2011.
-
(2011)
Kidney Int
, vol.79
, pp. 1361-1369
-
-
Chawla, L.S.1
Amdur, R.L.2
Amodeo, S.3
Kimmel, P.L.4
Palant, C.E.5
-
22
-
-
84865273555
-
Acute kidney injury and chronic kidney disease: An integrated clinical syndrome
-
Chawla LS, Kimmel PL. Acute kidney injury and chronic kidney disease: an integrated clinical syndrome. Kidney Int 82: 516-524, 2012.
-
(2012)
Kidney Int
, vol.82
, pp. 516-524
-
-
Chawla, L.S.1
Kimmel, P.L.2
-
23
-
-
81155131228
-
Platelet-derived growth factor receptor signaling activates pericyte-myofibroblast transition in obstructive and post-ischemic kidney fibrosis
-
Chen YT, Chang FC, Wu CF, Chou YH, Hsu HL, Chiang WC, Shen J, Chen YM, Wu KD, Tsai TJ, Duffield JS, Lin SL. Platelet-derived growth factor receptor signaling activates pericyte-myofibroblast transition in obstructive and post-ischemic kidney fibrosis. Kidney Int 80: 1170-1181, 2011.
-
(2011)
Kidney Int
, vol.80
, pp. 1170-1181
-
-
Chen, Y.T.1
Chang, F.C.2
Wu, C.F.3
Chou, Y.H.4
Hsu, H.L.5
Chiang, W.C.6
Shen, J.7
Chen, Y.M.8
Wu, K.D.9
Tsai, T.J.10
Duffield, J.S.11
Lin, S.L.12
-
24
-
-
11144357304
-
COMP-Ang1: A designed angiopoietin-1 variant with nonleaky angiogenic activity
-
Cho CH, Kammerer RA, Lee HJ, Steinmetz MO, Ryu YS, Lee SH, Yasunaga K, Kim KT, Kim I, Choi HH, Kim W, Kim SH, Park SK, Lee GM, Koh GY. COMP-Ang1: a designed angiopoietin-1 variant with nonleaky angiogenic activity. Proc Natl Acad Sci USA 101: 5547-5552, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 5547-5552
-
-
Cho, C.H.1
Kammerer, R.A.2
Lee, H.J.3
Steinmetz, M.O.4
Ryu, Y.S.5
Lee, S.H.6
Yasunaga, K.7
Kim, K.T.8
Kim, I.9
Choi, H.H.10
Kim, W.11
Kim, S.H.12
Park, S.K.13
Lee, G.M.14
Koh, G.Y.15
-
25
-
-
84857112728
-
Chronic kidney disease after acute kidney injury: A systematic review and meta-analysis
-
Coca SG, Singanamala S, Parikh CR. Chronic kidney disease after acute kidney injury: a systematic review and meta-analysis. Kidney Int 81: 442-448, 2012.
-
(2012)
Kidney Int
, vol.81
, pp. 442-448
-
-
Coca, S.G.1
Singanamala, S.2
Parikh, C.R.3
-
26
-
-
84858204846
-
Hypoxia inducible factor 1-alpha (HIF-1 alpha) is induced during reperfusion after renal ischemia and is critical for proximal tubule cell survival
-
Conde E, Alegre L, Blanco-Sánchez I, Sáenz-Morales D, Aguado-Fraile E, Ponte B, Ramos E, Sáiz A, Jiménez C, Ordoñez A, López-Cabrera M, del Peso L, de Landázuri MO, Liaño F, Selgas R, Sanchez-Tomero JA, García-Bermejo ML. Hypoxia inducible factor 1-alpha (HIF-1 alpha) is induced during reperfusion after renal ischemia and is critical for proximal tubule cell survival. PLoS One 7: e33258, 2012.
-
(2012)
Plos One
, vol.7
-
-
Conde, E.1
Alegre, L.2
Blanco-Sánchez, I.3
Sáenz-Morales, D.4
Aguado-Fraile, E.5
Ponte, B.6
Ramos, E.7
Sáiz, A.8
Jiménez, C.9
Ordoñez, A.10
López-Cabrera, M.11
Del Peso, L.12
De Landázuri, M.O.13
Liaño, F.14
Selgas, R.15
Sanchez-Tomero, J.A.16
García-Bermejo, M.L.17
-
27
-
-
84855297121
-
The p53 inhibitor pifithrin-a can stimulate fibrosis in a rat model of ischemic acute kidney injury
-
Dagher PC, Mai EM, Hato T, Lee SY, Anderson MD, Karozos SC, Mang HE, Knipe NL, Plotkin Z, Sutton TA. The p53 inhibitor pifithrin-a can stimulate fibrosis in a rat model of ischemic acute kidney injury. Am J Physiol Renal Physiol 302: F284-F291, 2012.
-
(2012)
Am J Physiol Renal Physiol
, vol.302
, pp. F284-F291
-
-
Dagher, P.C.1
Mai, E.M.2
Hato, T.3
Lee, S.Y.4
Erson, M.D.5
Karozos, S.C.6
Mang, H.E.7
Knipe, N.L.8
Plotkin, Z.9
Sutton, T.A.10
-
28
-
-
33748329385
-
Role of hypoxia in the pathogenesis of renal disease
-
Eckardt KU, Bernhardt WM, Weidemann A, Warnecke C, Rosen-berger C, Wiesener MS, Willam C. Role of hypoxia in the pathogenesis of renal disease. Kidney Int Suppl: S46-51, 2005.
-
(2005)
Kidney Int Suppl
, pp. S46-S51
-
-
Eckardt, K.U.1
Bernhardt, W.M.2
Weidemann, A.3
Warnecke, C.4
Rosen-Berger, C.5
Wiesener, M.S.6
Willam, C.7
-
31
-
-
40849130173
-
VEGF inhibition and renal thrombotic microangiopathy
-
Eremina V, Jefferson JA, Kowalewska J, Hochster H, Haas M, Weisstuch J, Richardson C, Kopp JB, Kabir MG, Backx PH, Gerber HP, Ferrara N, Barisoni L, Alpers CE, Quaggin SE. VEGF inhibition and renal thrombotic microangiopathy. N Engl J Med 358: 1129-1136, 2008.
-
(2008)
N Engl J Med
, vol.358
, pp. 1129-1136
-
-
Eremina, V.1
Jefferson, J.A.2
Kowalewska, J.3
Hochster, H.4
Haas, M.5
Weisstuch, J.6
Richardson, C.7
Kopp, J.B.8
Kabir, M.G.9
Backx, P.H.10
Gerber, H.P.11
Ferrara, N.12
Barisoni, L.13
Alpers, C.E.14
Quaggin, S.E.15
-
32
-
-
0034037110
-
Is there a common mechanism for the progression of different types of renal diseases other than proteinuria? Towards the unifying theme of chronic hypoxia
-
Fine LG, Bandyopadhay D, Norman JT. Is there a common mechanism for the progression of different types of renal diseases other than proteinuria? Towards the unifying theme of chronic hypoxia. Kidney Int Suppl 75: S22-26, 2000.
-
(2000)
Kidney Int Suppl
, vol.75
, pp. S22-S26
-
-
Fine, L.G.1
Bandyopadhay, D.2
Norman, J.T.3
-
33
-
-
51849094304
-
Chronic hypoxia as a mechanism of progression of chronic kidney diseases: From hypothesis to novel therapeutics
-
Fine LG, Norman JT. Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics. Kidney Int 74: 867-872, 2008.
-
(2008)
Kidney Int
, vol.74
, pp. 867-872
-
-
Fine, L.G.1
Norman, J.T.2
-
34
-
-
84886424419
-
Kidney hypoxia, attributable to increased oxygen consumption, induces nephropathy independently of hyperglycemia and oxidative stress
-
Friederich-Persson M, Thörn E, Hansell P, Nangaku M, Levin M, Palm F. Kidney hypoxia, attributable to increased oxygen consumption, induces nephropathy independently of hyperglycemia and oxidative stress. Hypertension 62: 914-919, 2013.
-
(2013)
Hypertension
, vol.62
, pp. 914-919
-
-
Friederich-Persson, M.1
Thörn, E.2
Hansell, P.3
Nangaku, M.4
Levin, M.5
Palm, F.6
-
35
-
-
39449120049
-
Albuminuria and estimated GFR 5 years after Escherichia coli O157 hemolytic uremic syndrome: An update
-
Garg AX, Salvadori M, Okell JM, Thiessen-Philbrook HR, Suri RS, Filler G, Moist L, Matsell D, Clark WF. Albuminuria and estimated GFR 5 years after Escherichia coli O157 hemolytic uremic syndrome: an update. Am J Kidney Dis 51: 435–444, 2008.
-
(2008)
Am J Kidney Dis
, vol.51
, pp. 435-444
-
-
Garg, A.X.1
Salvadori, M.2
Okell, J.M.3
Thiessen-Philbrook, H.R.4
Suri, R.S.5
Filler, G.6
Moist, L.7
Matsell, D.8
Clark, W.F.9
-
36
-
-
65349114100
-
Inhibition of autoregulated TGFbeta signaling simultaneously enhances proliferation and differentiation of kidney epithelium and promotes repair following renal ischemia
-
Geng H, Lan R, Wang G, Siddiqi AR, Naski MC, Brooks AI, Barnes JL, Saikumar P, Weinberg JM, Venkatachalam MA. Inhibition of autoregulated TGFbeta signaling simultaneously enhances proliferation and differentiation of kidney epithelium and promotes repair following renal ischemia. Am J Pathol 174: 1291-1308, 2009.
-
(2009)
Am J Pathol
, vol.174
, pp. 1291-1308
-
-
Geng, H.1
Lan, R.2
Wang, G.3
Siddiqi, A.R.4
Naski, M.C.5
Brooks, A.I.6
Barnes, J.L.7
Saikumar, P.8
Weinberg, J.M.9
Venkatachalam, M.A.10
-
37
-
-
0029564901
-
Control of mitochondrial and cellular respiration by oxygen
-
Gnaiger E, Steinlechner-Maran R, Méndez G, Eberl T, Margreiter R. Control of mitochondrial and cellular respiration by oxygen. J Bio-energ Biomembr 27: 583-596, 1995.
-
(1995)
J Bio-Energ Biomembr
, vol.27
, pp. 583-596
-
-
Gnaiger, E.1
Steinlechner-Maran, R.2
Méndez, G.3
Eberl, T.4
Margreiter, R.5
-
38
-
-
84900343814
-
Increased progression to kidney fibrosis after erythropoietin is used as a treatment for acute kidney injury
-
Gobe GC, Bennett NC, West M, Colditz P, Brown L, Vesey DA, Johnson DW. Increased progression to kidney fibrosis after erythropoietin is used as a treatment for acute kidney injury. Am J Physiol Renal Physiol 306: F681-F692, 2014.
-
(2014)
Am J Physiol Renal Physiol
, vol.306
, pp. F681-F692
-
-
Gobe, G.C.1
Bennett, N.C.2
West, M.3
Colditz, P.4
Brown, L.5
Vesey, D.A.6
Johnson, D.W.7
-
39
-
-
0028848487
-
Expression of vascular endothelial growth factor in renal vascular disease and renal allografts
-
Gröne HJ, Simon M, Gröne EF. Expression of vascular endothelial growth factor in renal vascular disease and renal allografts. J Pathol 177: 259-267, 1995.
-
(1995)
J Pathol
, vol.1-77
, pp. 259-267
-
-
Gröne, H.J.1
Simon, M.2
Gröne, E.F.3
-
40
-
-
0029012868
-
Calibration of misonidazole labeling by simultaneous measurement of oxygen tension and labeling density in multicellular spheroids
-
Gross MW, Karbach U, Groebe K, Franko AJ, Mueller-Klieser W. Calibration of misonidazole labeling by simultaneous measurement of oxygen tension and labeling density in multicellular spheroids. Int J Cancer 61: 567-573, 1995.
-
(1995)
Int J Cancer
, vol.61
, pp. 567-573
-
-
Gross, M.W.1
Karbach, U.2
Groebe, K.3
Franko, A.J.4
Mueller-Klieser, W.5
-
41
-
-
84872134149
-
Regulation of erythropoiesis by hypoxia-inducible factors
-
Haase VH. Regulation of erythropoiesis by hypoxia-inducible factors. Blood Rev 27: 41–53, 2013.
-
(2013)
Blood Rev
, vol.27
, pp. 41-53
-
-
Haase, V.H.1
-
42
-
-
47149092668
-
Renal parenchy-mal hypoxia, hypoxia response and the progression of chronic kidney disease
-
Heyman SN, Khamaisi M, Rosen S, Rosenberger C. Renal parenchy-mal hypoxia, hypoxia response and the progression of chronic kidney disease. Am J Nephrol 28: 998–1006, 2008.
-
(2008)
Am J Nephrol
, vol.28
, pp. 998-1006
-
-
Heyman, S.N.1
Khamaisi, M.2
Rosen, S.3
Rosenberger, C.4
-
43
-
-
72949089927
-
Experimental ischemia-reper-fusion: Biases and myths-the proximal vs. distal hypoxic tubular injury debate revisited
-
Heyman SN, Rosenberger C, Rosen S. Experimental ischemia-reper-fusion: biases and myths-the proximal vs. distal hypoxic tubular injury debate revisited. Kidney Int 77: 9–16, 2010.
-
(2010)
Kidney Int
, vol.77
, pp. 9-16
-
-
Heyman, S.N.1
Rosenberger, C.2
Rosen, S.3
-
44
-
-
38149075003
-
Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury
-
Hill P, Shukla D, Tran MG, Aragones J, Cook HT, Carmeliet P, Maxwell PH. Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury. J Am Soc Nephrol 19: 39–46, 2008.
-
(2008)
J am Soc Nephrol
, vol.19
, pp. 39-46
-
-
Hill, P.1
Shukla, D.2
Tran, M.G.3
Aragones, J.4
Cook, H.T.5
Carmeliet, P.6
Maxwell, P.H.7
-
45
-
-
34548647550
-
Acute and chronic microvascular alterations in a mouse model of ischemic acute kidney injury
-
Hörbelt M, Lee SY, Mang HE, Knipe NL, Sado Y, Kribben A, Sutton TA. Acute and chronic microvascular alterations in a mouse model of ischemic acute kidney injury. Am J Physiol Renal Physiol 293: F688–F695, 2007.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
, pp. F688-F695
-
-
Hörbelt, M.1
Lee, S.Y.2
Mang, H.E.3
Knipe, N.L.4
Sado, Y.5
Kribben, A.6
Sutton, T.A.7
-
46
-
-
84861828323
-
Yes, AKI truly leads to CKD
-
Hsu CY. Yes, AKI truly leads to CKD. J Am Soc Nephrol 23: 967–969, 2012.
-
(2012)
J am Soc Nephrol
, vol.23
, pp. 967-969
-
-
Hsu, C.Y.1
-
47
-
-
73949096744
-
Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis
-
Humphreys BD, Lin SL, Kobayashi A, Hudson TE, Nowlin BT, Bonventre JV, Valerius MT, McMahon AP, Duffield JS. Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am J Pathol 176: 85–97, 2010.
-
(2010)
Am J Pathol
, vol.176
, pp. 85-97
-
-
Humphreys, B.D.1
Lin, S.L.2
Kobayashi, A.3
Hudson, T.E.4
Nowlin, B.T.5
Bonventre, J.V.6
Valerius, M.T.7
McMahon, A.P.8
Duffield, J.S.9
-
48
-
-
39749172401
-
Intrinsic epithelial cells repair the kidney after injury
-
Humphreys BD, Valerius MT, Kobayashi A, Mugford JW, Soeung S, Duffield JS, McMahon AP, Bonventre JV. Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell 2: 284–291, 2008.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 284-291
-
-
Humphreys, B.D.1
Valerius, M.T.2
Kobayashi, A.3
Mugford, J.W.4
Soeung, S.5
Duffield, J.S.6
McMahon, A.P.7
Bonventre, J.V.8
-
49
-
-
79960957297
-
Non-invasive evaluation of kidney hypoxia and fibrosis using magnetic resonance imaging
-
Inoue T, Kozawa E, Okada H, Inukai K, Watanabe S, Kikuta T, Watanabe Y, Takenaka T, Katayama S, Tanaka J, Suzuki H. Non-invasive evaluation of kidney hypoxia and fibrosis using magnetic resonance imaging. J Am Soc Nephrol 22: 1429–1434, 2011.
-
(2011)
J am Soc Nephrol
, vol.22
, pp. 1429-1434
-
-
Inoue, T.1
Kozawa, E.2
Okada, H.3
Inukai, K.4
Watanabe, S.5
Kikuta, T.6
Watanabe, Y.7
Takenaka, T.8
Katayama, S.9
Tanaka, J.10
Suzuki, H.11
-
50
-
-
79951522913
-
The magnitude of acute serum creatinine increase after cardiac surgery and the risk of chronic kidney disease, progression of kidney disease, and death
-
Ishani A, Nelson D, Clothier B, Schult T, Nugent S, Greer N, Slinin Y, Ensrud KE. The magnitude of acute serum creatinine increase after cardiac surgery and the risk of chronic kidney disease, progression of kidney disease, and death. Arch Intern Med 171: 226–233, 2011.
-
(2011)
Arch Intern Med
, vol.171
, pp. 226-233
-
-
Ishani, A.1
Nelson, D.2
Clothier, B.3
Schult, T.4
Nugent, S.5
Greer, N.6
Slinin, Y.7
Ensrud, K.E.8
-
51
-
-
58149485462
-
Acute kidney injury increases risk of ESRD among elderly
-
Ishani A, Xue JL, Himmelfarb J, Eggers PW, Kimmel PL, Molitoris BA, Collins AJ. Acute kidney injury increases risk of ESRD among elderly. J Am Soc Nephrol 20: 223–228, 2009.
-
(2009)
J am Soc Nephrol
, vol.20
, pp. 223-228
-
-
Ishani, A.1
Xue, J.L.2
Himmelfarb, J.3
Eggers, P.W.4
Kimmel, P.L.5
Molitoris, B.A.6
Collins, A.J.7
-
52
-
-
0035917313
-
HIFalpha targeted for VHL-medi-ated destruction by proline hydroxylation: Implications for O2 sensing
-
Ivan M, Kondo K, Yang H, Kim W, Valiando J, Ohh M, Salic A, Asara JM, Lane WS, Kaelin WG. HIFalpha targeted for VHL-medi-ated destruction by proline hydroxylation: implications for O2 sensing. Science 292: 464–468, 2001.
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin, W.G.10
-
53
-
-
15444342958
-
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha
-
Iyer NV, Kotch LE, Agani F, Leung SW, Laughner E, Wenger RH, Gassmann M, Gearhart JD, Lawler AM, Yu AY, Semenza GL. Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes Dev 12: 149–162, 1998.
-
(1998)
Genes Dev
, vol.12
, pp. 149-162
-
-
Iyer, N.V.1
Kotch, L.E.2
Agani, F.3
Leung, S.W.4
Laughner, E.5
Wenger, R.H.6
Gassmann, M.7
Gearhart, J.D.8
Lawler, A.M.9
Yu, A.Y.10
Semenza, G.L.11
-
54
-
-
0035917808
-
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxy-lation
-
Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ, von Kriegsheim A, Hebestreit HF, Mukherji M, Schofield CJ, Maxwell PH, Pugh CW, Ratcliffe PJ. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxy-lation. Science 292: 468–472, 2001.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Von Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
55
-
-
84865601727
-
Treatment with a novel hypoxia-inducible factor hydroxylase inhibitor (TRC160334) ameliorates ischemic acute kidney injury
-
Jamadarkhana P, Chaudhary A, Chhipa L, Dubey A, Mohanan A, Gupta R, Deshpande S. Treatment with a novel hypoxia-inducible factor hydroxylase inhibitor (TRC160334) ameliorates ischemic acute kidney injury. Am J Nephrol 36: 208–218, 2012.
-
(2012)
Am J Nephrol
, vol.36
, pp. 208-218
-
-
Jamadarkhana, P.1
Chaudhary, A.2
Chhipa, L.3
Dubey, A.4
Mohanan, A.5
Gupta, R.6
Deshpande, S.7
-
56
-
-
0029999449
-
Endotoxin-induced changes in intrarenal pO2, measured by in vivo electron paramagnetic resonance oximetry and magnetic resonance imaging
-
James PE, Bacic G, Grinberg OY, Goda F, Dunn JF, Jackson SK, Swartz HM. Endotoxin-induced changes in intrarenal pO2, measured by in vivo electron paramagnetic resonance oximetry and magnetic resonance imaging. Free Radic Biol Med 21: 25–34, 1996.
-
(1996)
Free Radic Biol Med
, vol.21
, pp. 25-34
-
-
James, P.E.1
Bacic, G.2
Grinberg, O.Y.3
Goda, F.4
Dunn, J.F.5
Jackson, S.K.6
Swartz, H.M.7
-
57
-
-
40649114443
-
Hypoxia induces a novel signature of chromatin modifications and global repression of transcription
-
Johnson AB, Denko N, Barton MC. Hypoxia induces a novel signature of chromatin modifications and global repression of transcription. Mutat Res 640: 174–179, 2008.
-
(2008)
Mutat Res
, vol.640
, pp. 174-179
-
-
Johnson, A.B.1
Denko, N.2
Barton, M.C.3
-
58
-
-
84865689386
-
Association of complete recovery from acute kidney injury with incident CKD stage 3 and all-cause mortality
-
Jones J, Holmen J, De Graauw J, Jovanovich A, Thornton S, Chonchol M. Association of complete recovery from acute kidney injury with incident CKD stage 3 and all-cause mortality. Am J Kidney Dis 60: 402–408, 2012.
-
(2012)
Am J Kidney Dis
, vol.60
, pp. 402-408
-
-
Jones, J.1
Holmen, J.2
De Graauw, J.3
Jovanovich, A.4
Thornton, S.5
Chonchol, M.6
-
59
-
-
70349647202
-
Peritubular capillary preservation with COMP-angiopoietin-1 decreases ischemia-reperfusion-induced acute kidney injury
-
Jung YJ, Kim DH, Lee AS, Lee S, Kang KP, Lee SY, Jang KY, Sung MJ, Park SK, Kim W. Peritubular capillary preservation with COMP-angiopoietin-1 decreases ischemia-reperfusion-induced acute kidney injury. Am J Physiol Renal Physiol 297: F952–F960, 2009.
-
(2009)
Am J Physiol Renal Physiol
, vol.297
, pp. F952-F960
-
-
Jung, Y.J.1
Kim, D.H.2
Lee, A.S.3
Lee, S.4
Kang, K.P.5
Lee, S.Y.6
Jang, K.Y.7
Sung, M.J.8
Park, S.K.9
Kim, W.10
-
60
-
-
32944474182
-
VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature
-
Kamba T, Tam BY, Hashizume H, Haskell A, Sennino B, Mancuso MR, Norberg SM, O’Brien SM, Davis RB, Gowen LC, Anderson KD, Thurston G, Joho S, Springer ML, Kuo CJ, McDonald DM. VEGF-dependent plasticity of fenestrated capillaries in the normal adult microvasculature. Am J Physiol Heart Circ Physiol 290: H560–H576, 2006.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
, pp. H560-H576
-
-
Kamba, T.1
Tam, B.Y.2
Hashizume, H.3
Haskell, A.4
Sennino, B.5
Mancuso, M.R.6
Norberg, S.M.7
O’Brien, S.M.8
Davis, R.B.9
Gowen, L.C.10
Erson, K.D.11
Thurston, G.12
Joho, S.13
Springer, M.L.14
Kuo, C.J.15
McDonald, D.M.16
-
61
-
-
84860508117
-
Preischemic targeting of HIF prolyl hydroxyla-tion inhibits fibrosis associated with acute kidney injury
-
Kapitsinou PP, Jaffe J, Michael M, Swan CE, Duffy KJ, Erickson-Miller CL, Haase VH. Preischemic targeting of HIF prolyl hydroxyla-tion inhibits fibrosis associated with acute kidney injury. Am J Physiol Renal Physiol 302: F1172-F1179, 2012.
-
(2012)
Am J Physiol Renal Physiol
, vol.302
, pp. F1172-F1179
-
-
Kapitsinou, P.P.1
Jaffe, J.2
Michael, M.3
Swan, C.E.4
Duffy, K.J.5
Erickson-Miller, C.L.6
Haase, V.H.7
-
62
-
-
84902172100
-
Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury
-
Kapitsinou PP, Sano H, Michael M, Kobayashi H, Davidoff O, Bian A, Yao B, Zhang MZ, Harris RC, Duffy KJ, Erickson-Miller CL, Sutton TA, Haase VH. Endothelial HIF-2 mediates protection and recovery from ischemic kidney injury. J Clin Invest 124: 2396-2409, 2014.
-
(2014)
J Clin Invest
, vol.124
, pp. 2396-2409
-
-
Kapitsinou, P.P.1
Sano, H.2
Michael, M.3
Kobayashi, H.4
Davidoff, O.5
Bian, A.6
Yao, B.7
Zhang, M.Z.8
Harris, R.C.9
Duffy, K.J.10
Erickson-Miller, C.L.11
Sutton, T.A.12
Haase, V.H.13
-
63
-
-
0032830209
-
Hypoxia induces renal tubular epithelial cell apoptosis in chronic renal disease
-
Khan S, Cleveland RP, Koch CJ, Schelling JR. Hypoxia induces renal tubular epithelial cell apoptosis in chronic renal disease. Lab Invest 79: 1089-1099, 1999.
-
(1999)
Lab Invest
, vol.79
, pp. 1089-1099
-
-
Khan, S.1
Cleveland, R.P.2
Koch, C.J.3
Schelling, J.R.4
-
64
-
-
84875748988
-
EphrinB2 reverse signaling protects against capillary rarefaction and fibrosis after kidney injury
-
Kida Y, Ieronimakis N, Schrimpf C, Reyes M, Duffield JS. EphrinB2 reverse signaling protects against capillary rarefaction and fibrosis after kidney injury. J Am Soc Nephrol 24: 559-572, 2013.
-
(2013)
J am Soc Nephrol
, vol.24
, pp. 559-572
-
-
Kida, Y.1
Ieronimakis, N.2
Schrimpf, C.3
Reyes, M.4
Duffield, J.S.5
-
65
-
-
34047228387
-
Protective role of hypoxia-inducible factor-2alpha against ischemic damage and oxidative stress in the kidney
-
Kojima I, Tanaka T, Inagi R, Kato H, Yamashita T, Sakiyama A, Ohneda O, Takeda N, Sata M, Miyata T, Fujita T, Nangaku M. Protective role of hypoxia-inducible factor-2alpha against ischemic damage and oxidative stress in the kidney. J Am Soc Nephrol 18: 1218-1226, 2007.
-
(2007)
J am Soc Nephrol
, vol.18
, pp. 1218-1226
-
-
Kojima, I.1
Tanaka, T.2
Inagi, R.3
Kato, H.4
Yamashita, T.5
Sakiyama, A.6
Ohneda, O.7
Takeda, N.8
Sata, M.9
Miyata, T.10
Fujita, T.11
Nangaku, M.12
-
66
-
-
67349216805
-
A genetic variant of hypoxia-inducible factor-1alpha is associated with adverse outcomes in acute kidney injury
-
Kolyada AY, Tighiouart H, Perianayagam MC, Liangos O, Madias NE, Jaber BL. A genetic variant of hypoxia-inducible factor-1alpha is associated with adverse outcomes in acute kidney injury. Kidney Int 75: 1322-1329, 2009.
-
(2009)
Kidney Int
, vol.75
, pp. 1322-1329
-
-
Kolyada, A.Y.1
Tighiouart, H.2
Perianayagam, M.C.3
Liangos, O.4
Madias, N.E.5
Jaber, B.L.6
-
67
-
-
3142752573
-
Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of beta2 integrin gene expression
-
Kong T, Eltzschig HK, Karhausen J, Colgan SP, Shelley CS. Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of beta2 integrin gene expression. Proc Natl Acad Sci USA 101: 10440-10445, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10440-10445
-
-
Kong, T.1
Eltzschig, H.K.2
Karhausen, J.3
Colgan, S.P.4
Shelley, C.S.5
-
68
-
-
84913593835
-
Fluorescence microangiography for quantitative assessment of peritubular capillary changes after AKI in mice
-
Kramann R, Tanaka M, Humphreys BD. Fluorescence microangiography for quantitative assessment of peritubular capillary changes after AKI in mice. J Am Soc Nephrol 25: 1924-1931, 2014.
-
(2014)
J am Soc Nephrol
, vol.25
, pp. 1924-1931
-
-
Kramann, R.1
Tanaka, M.2
Humphreys, B.D.3
-
69
-
-
84893369728
-
Differentiated kidney epithelial cells repair injured proximal tubule
-
Kusaba T, Lalli M, Kramann R, Kobayashi A, Humphreys BD. Differentiated kidney epithelial cells repair injured proximal tubule. Proc Natl Acad Sci USA 111: 1527-1532, 2014.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 1527-1532
-
-
Kusaba, T.1
Lalli, M.2
Kramann, R.3
Kobayashi, A.4
Humphreys, B.D.5
-
70
-
-
84860520663
-
PTEN loss defines a TGF- fj-induced tubule phe-notype of failed differentiation and JNK signaling during renal fibrosis
-
Lan R, Geng H, Polichnowski AJ, Singha PK, Saikumar P, McEwen DG, Griffin KA, Koesters R, Weinberg JM, Bidani AK, Kriz W, Venkatachalam MA. PTEN loss defines a TGF- fj-induced tubule phe-notype of failed differentiation and JNK signaling during renal fibrosis. Am J Physiol Renal Physiol 302: F1210-F1223, 2012.
-
(2012)
Am J Physiol Renal Physiol
, vol.302
, pp. F1210-F1223
-
-
Lan, R.1
Geng, H.2
Polichnowski, A.J.3
Singha, P.K.4
Saikumar, P.5
McEwen, D.G.6
Griffin, K.A.7
Koesters, R.8
Weinberg, J.M.9
Bidani, A.K.10
Kriz, W.11
Venkatachalam, M.A.12
-
71
-
-
84882289111
-
Origin and function of myofibroblasts in kidney fibrosis
-
LeBleu VS, Taduri G, O’Connell J, Teng Y, Cooke VG, Woda C, Sugimoto H, Kalluri R. Origin and function of myofibroblasts in kidney fibrosis. Nat Med 19: 1047-1053, 2013.
-
(2013)
Nat Med
, vol.19
, pp. 1047-1053
-
-
Lebleu, V.S.1
Taduri, G.2
O’Connell, J.3
Teng, Y.4
Cooke, V.G.5
Woda, C.6
Sugimoto, H.7
Kalluri, R.8
-
72
-
-
48149111863
-
Renal hypoxia and dysoxia after reperfusion of the ischemic kidney
-
Legrand M, Mik EG, Johannes T, Payen D, Ince C. Renal hypoxia and dysoxia after reperfusion of the ischemic kidney. Mol Med 14: 502-516, 2008.
-
(2008)
Mol Med
, vol.14
, pp. 502-516
-
-
Legrand, M.1
Mik, E.G.2
Johannes, T.3
Payen, D.4
Ince, C.5
-
73
-
-
0025851495
-
Changes in regional renal perfusion following ischemia/reperfusion injury to the rat kidney
-
Lennon GM, Ryan PC, Gaffney EF, Fitzpatrick JM. Changes in regional renal perfusion following ischemia/reperfusion injury to the rat kidney. Urol Res 19: 259-264, 1991.
-
(1991)
Urol Res
, vol.19
, pp. 259-264
-
-
Lennon, G.M.1
Ryan, P.C.2
Gaffney, E.F.3
Fitzpatrick, J.M.4
-
74
-
-
57349093841
-
VEGF-121 preserves renal microvessel structure and ameliorates secondary renal disease following acute kidney injury
-
Leonard EC, Friedrich JL, Basile DP. VEGF-121 preserves renal microvessel structure and ameliorates secondary renal disease following acute kidney injury. Am J Physiol Renal Physiol 295: F1648-F1657, 2008.
-
(2008)
Am J Physiol Renal Physiol
, vol.295
, pp. F1648-F1657
-
-
Leonard, E.C.1
Friedrich, J.L.2
Basile, D.P.3
-
75
-
-
25744452959
-
Diffusion of oxygen from arterial to venous segments of renal capillaires
-
Levy MN, Sauceda G. Diffusion of oxygen from arterial to venous segments of renal capillaires. Am J Physiol 196: 1336-1339, 1959.
-
(1959)
Am J Physiol
, vol.196
, pp. 1336-1339
-
-
Levy, M.N.1
Sauceda, G.2
-
76
-
-
79951816985
-
Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis
-
Lin SL, Chang FC, Schrimpf C, Chen YT, Wu CF, Wu VC, Chiang WC, Kuhnert F, Kuo CJ, Chen YM, Wu KD, Tsai TJ, Duffield JS. Targeting endothelium-pericyte cross talk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis. Am J Pathol 178: 911-923, 2011.
-
(2011)
Am J Pathol
, vol.178
, pp. 911-923
-
-
Lin, S.L.1
Chang, F.C.2
Schrimpf, C.3
Chen, Y.T.4
Wu, C.F.5
Wu, V.C.6
Chiang, W.C.7
Kuhnert, F.8
Kuo, C.J.9
Chen, Y.M.10
Wu, K.D.11
Tsai, T.J.12
Duffield, J.S.13
-
77
-
-
0031423816
-
Intrarenal oxygen tension measured by a modified clark electrode at normal and low blood pressure and after injection of x-ray contrast media
-
Liss P, Nygren A, Revsbech NP, Ulfendahl HR. Intrarenal oxygen tension measured by a modified clark electrode at normal and low blood pressure and after injection of x-ray contrast media. Pflügers Arch 434: 705-711, 1997.
-
(1997)
Pflügers Arch
, vol.434
, pp. 705-711
-
-
Liss, P.1
Nygren, A.2
Revsbech, N.P.3
Ulfendahl, H.R.4
-
78
-
-
84900534164
-
Novel cardiolipin therapeutic protects endothelial mitochondria during renal ischemia and mitigates microvascular rarefaction, inflammation, and fibrosis
-
Liu S, Soong Y, Seshan SV, Szeto HH. Novel cardiolipin therapeutic protects endothelial mitochondria during renal ischemia and mitigates microvascular rarefaction, inflammation, and fibrosis. Am J Physiol Renal Physiol 306: F970-F980, 2014.
-
(2014)
Am J Physiol Renal Physiol
, vol.306
, pp. F970-F980
-
-
Liu, S.1
Soong, Y.2
Seshan, S.V.3
Szeto, H.H.4
-
79
-
-
70349673306
-
Dialysis-requiring acute renal failure increases the risk of progressive chronic kidney disease
-
Lo LJ, Go AS, Chertow GM, McCulloch CE, Fan D, Ordoñez JD, Hsu CY. Dialysis-requiring acute renal failure increases the risk of progressive chronic kidney disease. Kidney Int 76: 893-899, 2009.
-
(2009)
Kidney Int
, vol.76
, pp. 893-899
-
-
Lo, L.J.1
Go, A.S.2
Chertow, G.M.3
McCulloch, C.E.4
Fan, D.5
Ordoñez, J.D.6
Hsu, C.Y.7
-
80
-
-
65249167552
-
Xenon preconditioning protects against renal ischemic-reperfusion injury via HIF-1alpha activation
-
Ma D, Lim T, Xu J, Tang H, Wan Y, Zhao H, Hossain M, Maxwell PH, Maze M. Xenon preconditioning protects against renal ischemic-reperfusion injury via HIF-1alpha activation. J Am Soc Nephrol 20: 713-720, 2009.
-
(2009)
J am Soc Nephrol
, vol.20
, pp. 713-720
-
-
Ma, D.1
Lim, T.2
Xu, J.3
Tang, H.4
Wan, Y.5
Zhao, H.6
Hossain, M.7
Maxwell, P.H.8
Maze, M.9
-
81
-
-
84858964551
-
Long-term risk of CKD in children surviving episodes of acute kidney injury in the intensive care unit: A prospective cohort study
-
Mammen C, Al Abbas A, Skippen P, Nadel H, Levine D, Collet JP, Matsell DG. Long-term risk of CKD in children surviving episodes of acute kidney injury in the intensive care unit: a prospective cohort study. Am J Kidney Dis 59: 523–530, 2012.
-
(2012)
Am J Kidney Dis
, vol.59
, pp. 523-530
-
-
Mammen, C.1
Al Abbas, A.2
Skippen, P.3
Nadel, H.4
Levine, D.5
Collet, J.P.6
Matsell, D.G.7
-
82
-
-
10744229444
-
Transdifferen-tiation of cultured tubular cells induced by hypoxia
-
Manotham K, Tanaka T, Matsumoto M, Ohse T, Inagi R, Miyata T, Kurokawa K, Fujita T, Ingelfinger JR, Nangaku M. Transdifferen-tiation of cultured tubular cells induced by hypoxia. Kidney Int 65: 871–880, 2004.
-
(2004)
Kidney Int
, vol.65
, pp. 871-880
-
-
Manotham, K.1
Tanaka, T.2
Matsumoto, M.3
Ohse, T.4
Inagi, R.5
Miyata, T.6
Kurokawa, K.7
Fujita, T.8
Ingelfinger, J.R.9
Nangaku, M.10
-
83
-
-
0037530588
-
Induction of renoprotective gene expression by cobalt ameliorates ischemic injury of the kidney in rats
-
Matsumoto M, Makino Y, Tanaka T, Tanaka H, Ishizaka N, Noiri E, Fujita T, Nangaku M. Induction of renoprotective gene expression by cobalt ameliorates ischemic injury of the kidney in rats. J Am Soc Nephrol 14: 1825–1832, 2003.
-
(2003)
J am Soc Nephrol
, vol.14
, pp. 1825-1832
-
-
Matsumoto, M.1
Makino, Y.2
Tanaka, T.3
Tanaka, H.4
Ishizaka, N.5
Noiri, E.6
Fujita, T.7
Nangaku, M.8
-
84
-
-
79953886254
-
Capillary rarefaction, hypoxia, VEGF and angiogenesis in chronic renal disease
-
Mayer G. Capillary rarefaction, hypoxia, VEGF and angiogenesis in chronic renal disease. Nephrol Dial Transplant 26: 1132–1137, 2011.
-
(2011)
Nephrol Dial Transplant
, vol.26
, pp. 1132-1137
-
-
Mayer, G.1
-
85
-
-
84891560690
-
Revolution of nephrol-ogy research by deep sequencing
-
Mimura I, Kanki Y, Kodama T, Nangaku M. Revolution of nephrol-ogy research by deep sequencing: ChIP-seq and RNA-seq. Kidney Int 85: 31–38, 2014.
-
(2014)
Chip-Seq and Rna-Seq. Kidney Int
, vol.85
, pp. 31-38
-
-
Mimura, I.1
Kanki, Y.2
Kodama, T.3
Nangaku, M.4
-
86
-
-
78049378469
-
The suffocating kidney: Tubulointerstitial hyp-oxia in end-stage renal disease
-
Mimura I, Nangaku M. The suffocating kidney: tubulointerstitial hyp-oxia in end-stage renal disease. Nat Rev Nephrol 6: 667–678, 2010.
-
(2010)
Nat Rev Nephrol
, vol.6
, pp. 667-678
-
-
Mimura, I.1
Nangaku, M.2
-
87
-
-
84883527272
-
Novel therapeutic strategy with hypoxia-inducible factors via reversible epigenetic regulation mechanisms in progressive tubulointerstitial fibrosis
-
Mimura I, Tanaka T, Nangaku M. Novel therapeutic strategy with hypoxia-inducible factors via reversible epigenetic regulation mechanisms in progressive tubulointerstitial fibrosis. Semin Nephrol 33: 375–382, 2013.
-
(2013)
Semin Nephrol
, vol.33
, pp. 375-382
-
-
Mimura, I.1
Tanaka, T.2
Nangaku, M.3
-
88
-
-
67650531089
-
Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts
-
Mole DR, Blancher C, Copley RR, Pollard PJ, Gleadle JM, Ragous-sis J, Ratcliffe PJ. Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts. J Biol Chem 284: 16767–16775, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 16767-16775
-
-
Mole, D.R.1
Blancher, C.2
Copley, R.R.3
Pollard, P.J.4
Gleadle, J.M.5
Ragous-Sis, J.6
Ratcliffe, P.J.7
-
89
-
-
68049131578
-
BRG1 increases transcription of proinflammatory genes in renal ischemia
-
Naito M, Zager RA, Bomsztyk K. BRG1 increases transcription of proinflammatory genes in renal ischemia. J Am Soc Nephrol 20: 1787–1796, 2009.
-
(2009)
J am Soc Nephrol
, vol.20
, pp. 1787-1796
-
-
Naito, M.1
Zager, R.A.2
Bomsztyk, K.3
-
90
-
-
33645452371
-
Chronic hypoxia and tubulointerstitial injury: A final common pathway to end-stage renal failure
-
Nangaku M. Chronic hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure. J Am Soc Nephrol 17: 17–25, 2006.
-
(2006)
J am Soc Nephrol
, vol.17
, pp. 17-25
-
-
Nangaku, M.1
-
91
-
-
36849049298
-
Hypoxia and the HIF system in kidney disease
-
Nangaku M, Eckardt KU. Hypoxia and the HIF system in kidney disease. J Mol Med (Berl) 85: 1325–1330, 2007.
-
(2007)
J Mol Med (Berl)
, vol.85
, pp. 1325-1330
-
-
Nangaku, M.1
Eckardt, K.U.2
-
92
-
-
84873104259
-
Regulation of hypoxia-inducible factor in kidney disease
-
Nangaku M, Rosenberger C, Heyman SN, Eckardt KU. Regulation of hypoxia-inducible factor in kidney disease. Clin Exp Pharmacol Physiol 40: 148–157, 2013.
-
(2013)
Clin Exp Pharmacol Physiol
, vol.40
, pp. 148-157
-
-
Nangaku, M.1
Rosenberger, C.2
Heyman, S.N.3
Eckardt, K.U.4
-
93
-
-
0021118711
-
Renal oxygen and lactate metabolism in hemorrhagic shock. An experimental study
-
Nelimarkka O. Renal oxygen and lactate metabolism in hemorrhagic shock. An experimental study. Acta Chir Scand Suppl 518: 1–44, 1984.
-
(1984)
Acta Chir Scand Suppl
, vol.518
, pp. 1-44
-
-
Nelimarkka, O.1
-
94
-
-
84925155884
-
Vascular geometry and oxygen diffusion in the vicinity of artery-vein pairs in the kidney
-
10 September
-
Ngo JP, Kar S, Kett MM, Gardiner BS, Pearson JT, Smith DW, Ludbrook J, Bertram JF, Evans RG. Vascular geometry and oxygen diffusion in the vicinity of artery-vein pairs in the kidney. Am J Physiol Renal Physiol. First published 10 September 2014; doi: 10.1152/ajpre-nal.00382.2014.
-
(2014)
Am J Physiol Renal Physiol. First Published
-
-
Ngo, J.P.1
Kar, S.2
Kett, M.M.3
Gardiner, B.S.4
Pearson, J.T.5
Smith, D.W.6
Ludbrook, J.7
Bertram, J.F.8
Evans, R.G.9
-
95
-
-
0033662026
-
Hypoxia promotes fibrogenesis in human renal fibroblasts
-
Norman JT, Clark IM, Garcia PL. Hypoxia promotes fibrogenesis in human renal fibroblasts. Kidney Int 58: 2351–2366, 2000.
-
(2000)
Kidney Int
, vol.58
, pp. 2351-2366
-
-
Norman, J.T.1
Clark, I.M.2
Garcia, P.L.3
-
96
-
-
33846205660
-
Chronic NOS inhibition actuates endothelial-mesenchymal transformation
-
O’Riordan E, Mendelev N, Patschan S, Patschan D, Eskander J, Cohen-Gould L, Chander P, Goligorsky MS. Chronic NOS inhibition actuates endothelial-mesenchymal transformation. Am J Physiol Heart Circ Physiol 292: H285–H294, 2007.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
, pp. H285-H294
-
-
O’Riordan, E.1
Mendelev, N.2
Patschan, S.3
Patschan, D.4
Eskander, J.5
Cohen-Gould, L.6
Chander, P.7
Goligorsky, M.S.8
-
98
-
-
79959699693
-
Renal tubulointerstitial hypoxia: Cause and consequence of kidney dysfunction
-
Palm F, Nordquist L. Renal tubulointerstitial hypoxia: cause and consequence of kidney dysfunction. Clin Exp Pharmacol Physiol 38: 474–480, 2011.
-
(2011)
Clin Exp Pharmacol Physiol
, vol.38
, pp. 474-480
-
-
Palm, F.1
Nordquist, L.2
-
99
-
-
0034682513
-
The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling
-
Peng J, Zhang L, Drysdale L, Fong GH. The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling. Proc Natl Acad Sci USA 97: 8386–8391, 2000.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 8386-8391
-
-
Peng, J.1
Zhang, L.2
Drysdale, L.3
Fong, G.H.4
-
100
-
-
84907209245
-
Severe renal mass reduction impairs recovery and promotes fibrosis after AKI
-
Polichnowski AJ, Lan R, Geng H, Griffin KA, Venkatachalam MA, Bidani AK. Severe renal mass reduction impairs recovery and promotes fibrosis after AKI. J Am Soc Nephrol 25: 1496–1507, 2014.
-
(2014)
J am Soc Nephrol
, vol.25
, pp. 1496-1507
-
-
Polichnowski, A.J.1
Lan, R.2
Geng, H.3
Griffin, K.A.4
Venkatachalam, M.A.5
Bidani, A.K.6
-
101
-
-
40849124059
-
Hypoxia stimulus: An adaptive immune response during dendritic cell maturation
-
Rama I, Bruene B, Torras J, Koehl R, Cruzado JM, Bestard O, Franquesa M, Lloberas N, Weigert A, Herrero-Fresneda I, Gulias O, Grinyó JM. Hypoxia stimulus: An adaptive immune response during dendritic cell maturation. Kidney Int 73: 816–825, 2008.
-
(2008)
Kidney Int
, vol.73
, pp. 816-825
-
-
Rama, I.1
Bruene, B.2
Torras, J.3
Koehl, R.4
Cruzado, J.M.5
Bestard, O.6
Franquesa, M.7
Lloberas, N.8
Weigert, A.9
Herrero-Fresneda, I.10
Gulias, O.11
Grinyó, J.M.12
-
102
-
-
77954956038
-
Acute renal failure is NOT an “acute renal success”–a clinical study on the renal oxygen supply/demand relationship in acute kidney injury
-
Redfors B, Bragadottir G, Sellgren J, Swärd K, Ricksten SE. Acute renal failure is NOT an “acute renal success”–a clinical study on the renal oxygen supply/demand relationship in acute kidney injury. Crit Care Med 38: 1695–1701, 2010.
-
(2010)
Crit Care Med
, vol.38
, pp. 1695-1701
-
-
Redfors, B.1
Bragadottir, G.2
Sellgren, J.3
Swärd, K.4
Ricksten, S.E.5
-
104
-
-
77952477767
-
The role of tubulointerstitial inflammation in the progression of chronic renal failure
-
Rodríguez-Iturbe B, García García G. The role of tubulointerstitial inflammation in the progression of chronic renal failure. Nephron Clin Pract 116: c81–88, 2010.
-
(2010)
Nephron Clin Pract
, vol.116
, pp. c81-c88
-
-
Rodríguez-Iturbe, B.1
García García, G.2
-
105
-
-
42949166878
-
Evidence for sustained renal hypoxia and transient hypoxia adaptation in experimental rhabdomyol-ysis-induced acute kidney injury
-
Rosenberger C, Goldfarb M, Shina A, Bachmann S, Frei U, Eckardt KU, Schrader T, Rosen S, Heyman SN. Evidence for sustained renal hypoxia and transient hypoxia adaptation in experimental rhabdomyol-ysis-induced acute kidney injury. Nephrol Dial Transplant 23: 1135–1143, 2008.
-
(2008)
Nephrol Dial Transplant
, vol.23
, pp. 1135-1143
-
-
Rosenberger, C.1
Goldfarb, M.2
Shina, A.3
Bachmann, S.4
Frei, U.5
Eckardt, K.U.6
Schrader, T.7
Rosen, S.8
Heyman, S.N.9
-
106
-
-
19944432424
-
Up-regulation of HIF in experimental acute renal failure: Evidence for a protective transcrip-tional response to hypoxia
-
Rosenberger C, Heyman SN, Rosen S, Shina A, Goldfarb M, Griethe W, Frei U, Reinke P, Bachmann S, Eckardt KU. Up-regulation of HIF in experimental acute renal failure: evidence for a protective transcrip-tional response to hypoxia. Kidney Int 67: 531–542, 2005.
-
(2005)
Kidney Int
, vol.67
, pp. 531-542
-
-
Rosenberger, C.1
Heyman, S.N.2
Rosen, S.3
Shina, A.4
Goldfarb, M.5
Griethe, W.6
Frei, U.7
Reinke, P.8
Bachmann, S.9
Eckardt, K.U.10
-
107
-
-
18444380862
-
Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys
-
Rosenberger C, Mandriota S, Jürgensen JS, Wiesener MS, Hörstrup JH, Frei U, Ratcliffe PJ, Maxwell PH, Bachmann S, Eckardt KU. Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys. J Am Soc Nephrol 13: 1721–1732, 2002.
-
(2002)
J am Soc Nephrol
, vol.13
, pp. 1721-1732
-
-
Rosenberger, C.1
Mandriota, S.2
Jürgensen, J.S.3
Wiesener, M.S.4
Hörstrup, J.H.5
Frei, U.6
Ratcliffe, P.J.7
Maxwell, P.H.8
Bachmann, S.9
Eckardt, K.U.10
-
108
-
-
33846012220
-
Immunohistochem-ical detection of hypoxia-inducible factor-1alpha in human renal allograft biopsies
-
Rosenberger C, Pratschke J, Rudolph B, Heyman SN, Schindler R, Babel N, Eckardt KU, Frei U, Rosen S, Reinke P. Immunohistochem-ical detection of hypoxia-inducible factor-1alpha in human renal allograft biopsies. J Am Soc Nephrol 18: 343–351, 2007.
-
(2007)
J am Soc Nephrol
, vol.18
, pp. 343-351
-
-
Rosenberger, C.1
Pratschke, J.2
Rudolph, B.3
Heyman, S.N.4
Schindler, R.5
Babel, N.6
Eckardt, K.U.7
Frei, U.8
Rosen, S.9
Reinke, P.10
-
109
-
-
30444445382
-
Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production
-
Safran M, Kim WY, O’Connell F, Flippin L, Günzler V, Horner JW, Depinho RA, Kaelin WG. Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin production. Proc Natl Acad Sci USA 103: 105–110, 2006.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 105-110
-
-
Safran, M.1
Kim, W.Y.2
O’Connell, F.3
Flippin, L.4
Günzler, V.5
Horner, J.W.6
Depinho, R.A.7
Kaelin, W.G.8
-
110
-
-
80555148901
-
Hypoxia-inducible transcription factors stabilization in the thick ascending limb protects against ischemic acute kidney injury
-
Schley G, Klanke B, Schödel J, Forstreuter F, Shukla D, Kurtz A, Amann K, Wiesener MS, Rosen S, Eckardt KU, Maxwell PH, Willam C. Hypoxia-inducible transcription factors stabilization in the thick ascending limb protects against ischemic acute kidney injury. J Am Soc Nephrol 22: 2004–2015, 2011.
-
(2011)
J am Soc Nephrol
, vol.22
, pp. 2004-2015
-
-
Schley, G.1
Klanke, B.2
Schödel, J.3
Forstreuter, F.4
Shukla, D.5
Kurtz, A.6
Amann, K.7
Wiesener, M.S.8
Rosen, S.9
Eckardt, K.U.10
Maxwell, P.H.11
Willam, C.12
-
111
-
-
65649105473
-
HIF-prolyl hydroxylases in the rat kidney: Physiologic expression patterns and regulation in acute kidney injury
-
Schödel J, Klanke B, Weidemann A, Buchholz B, Bernhardt W, Bertog M, Amann K, Korbmacher C, Wiesener M, Warnecke C, Kurtz A, Eckardt KU, Willam C. HIF-prolyl hydroxylases in the rat kidney: physiologic expression patterns and regulation in acute kidney injury. Am J Pathol 174: 1663–1674, 2009.
-
(2009)
Am J Pathol
, vol.174
, pp. 1663-1674
-
-
Schödel, J.1
Klanke, B.2
Weidemann, A.3
Buchholz, B.4
Bernhardt, W.5
Bertog, M.6
Amann, K.7
Korbmacher, C.8
Wiesener, M.9
Warnecke, C.10
Kurtz, A.11
Eckardt, K.U.12
Willam, C.13
-
112
-
-
2442707596
-
The role of vascular endothelial growth factor (VEGF) in renal pathophysiology
-
Schrijvers BF, Flyvbjerg A, De Vriese AS. The role of vascular endothelial growth factor (VEGF) in renal pathophysiology. Kidney Int 65: 2003–2017, 2004.
-
(2004)
Kidney Int
, vol.65
, pp. 2003-2017
-
-
Schrijvers, B.F.1
Flyvbjerg, A.2
De Vriese, A.S.3
-
113
-
-
84860645452
-
Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury
-
Schrimpf C, Xin C, Campanholle G, Gill SE, Stallcup W, Lin SL, Davis GE, Gharib SA, Humphreys BD, Duffield JS. Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury. J Am Soc Nephrol 23: 868–883, 2012.
-
(2012)
J am Soc Nephrol
, vol.23
, pp. 868-883
-
-
Schrimpf, C.1
Xin, C.2
Campanholle, G.3
Gill, S.E.4
Stallcup, W.5
Lin, S.L.6
Davis, G.E.7
Gharib, S.A.8
Humphreys, B.D.9
Duffield, J.S.10
-
114
-
-
0025697093
-
Evidence for a preglomerular oxygen diffusion shunt in rat renal cortex
-
Schurek HJ, Jost U, Baumgärtl H, Bertram H, Heckmann U. Evidence for a preglomerular oxygen diffusion shunt in rat renal cortex. Am J Physiol Renal Fluid Electrolyte Physiol 259: F910–F915, 1990.
-
(1990)
Am J Physiol Renal Fluid Electrolyte Physiol
, vol.259
, pp. F910-F915
-
-
Schurek, H.J.1
Jost, U.2
Baumgärtl, H.3
Bertram, H.4
Heckmann, U.5
-
115
-
-
0344826529
-
Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice
-
Scortegagna M, Ding K, Oktay Y, Gaur A, Thurmond F, Yan LJ, Marck BT, Matsumoto AM, Shelton JM, Richardson JA, Bennett MJ, Garcia JA. Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice. Nat Genet 35: 331–340, 2003.
-
(2003)
Nat Genet
, vol.35
, pp. 331-340
-
-
Scortegagna, M.1
Ding, K.2
Oktay, Y.3
Gaur, A.4
Thurmond, F.5
Yan, L.J.6
Marck, B.T.7
Matsumoto, A.M.8
Shelton, J.M.9
Richardson, J.A.10
Bennett, M.J.11
Garcia, J.A.12
-
116
-
-
0030357278
-
Expression of vascular permeability factor (VPF/VEGF) is altered in many glomerular diseases
-
Shulman K, Rosen S, Tognazzi K, Manseau EJ, Brown LF. Expression of vascular permeability factor (VPF/VEGF) is altered in many glomerular diseases. J Am Soc Nephrol 7: 661–666, 1996.
-
(1996)
J am Soc Nephrol
, vol.7
, pp. 661-666
-
-
Shulman, K.1
Rosen, S.2
Tognazzi, K.3
Manseau, E.J.4
Brown, L.F.5
-
117
-
-
0028950364
-
Expression of vascular endothelial growth factor and its receptors in human renal ontogenesis and in adult kidney
-
Simon M, Gröne HJ, Jöhren O, Kullmer J, Plate KH, Risau W, Fuchs E. Expression of vascular endothelial growth factor and its receptors in human renal ontogenesis and in adult kidney. Am J Physiol Renal Fluid Electrolyte Physiol 268: F240–F250, 1995.
-
(1995)
Am J Physiol Renal Fluid Electrolyte Physiol
, vol.268
, pp. F240-F250
-
-
Simon, M.1
Gröne, H.J.2
Jöhren, O.3
Kullmer, J.4
Plate, K.H.5
Risau, W.6
Fuchs, E.7
-
118
-
-
0345164367
-
Receptors of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in fetal and adult human kidney: Localization and [125I]VEGF binding sites
-
Simon M, Röckl W, Hornig C, Gröne EF, Theis H, Weich HA, Fuchs E, Yayon A, Gröne HJ. Receptors of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in fetal and adult human kidney: localization and [125I]VEGF binding sites. J Am Soc Nephrol 9: 1032–1044, 1998.
-
(1998)
J am Soc Nephrol
, vol.9
, pp. 1032-1044
-
-
Simon, M.1
Röckl, W.2
Hornig, C.3
Gröne, E.F.4
Theis, H.5
Weich, H.A.6
Fuchs, E.7
Yayon, A.8
Gröne, H.J.9
-
119
-
-
84885060233
-
Plasticity of renal erythropoietin-producing cells governs fibrosis
-
Souma T, Yamazaki S, Moriguchi T, Suzuki N, Hirano I, Pan X, Minegishi N, Abe M, Kiyomoto H, Ito S, Yamamoto M. Plasticity of renal erythropoietin-producing cells governs fibrosis. J Am Soc Nephrol 24: 1599–1616, 2013.
-
(2013)
J am Soc Nephrol
, vol.24
, pp. 1599-1616
-
-
Souma, T.1
Yamazaki, S.2
Moriguchi, T.3
Suzuki, N.4
Hirano, I.5
Pan, X.6
Minegishi, N.7
Abe, M.8
Kiyomoto, H.9
Ito, S.10
Yamamoto, M.11
-
120
-
-
34548040204
-
Recovery from acute renal failure predisposes hypertension and secondary renal disease in response to elevated sodium
-
Spurgeon-Pechman KR, Donohoe DL, Mattson DL, Lund H, James L, Basile DP. Recovery from acute renal failure predisposes hypertension and secondary renal disease in response to elevated sodium. Am J Physiol Renal Physiol 293: F269–F278, 2007.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
, pp. F269-F278
-
-
Spurgeon-Pechman, K.R.1
Donohoe, D.L.2
Mattson, D.L.3
Lund, H.4
James, L.5
Basile, D.P.6
-
121
-
-
84879037862
-
Erythrocytosis and pulmonary hypertension in a mouse model of human HIF2A gain of function mutation
-
Tan Q, Kerestes H, Percy MJ, Pietrofesa R, Chen L, Khurana TS, Christofidou-Solomidou M, Lappin TR, Lee FS. Erythrocytosis and pulmonary hypertension in a mouse model of human HIF2A gain of function mutation. J Biol Chem 288: 17134–17144, 2013.
-
(2013)
J Biol Chem
, vol.288
, pp. 17134-17144
-
-
Tan, Q.1
Kerestes, H.2
Percy, M.J.3
Pietrofesa, R.4
Chen, L.5
Khurana, T.S.6
Christofidou-Solomidou, M.7
Lappin, T.R.8
Lee, F.S.9
-
122
-
-
0042235096
-
Hypoxia induces apoptosis in SV40-immortalized rat proximal tubular cells through the mitochondrial pathways, devoid of HIF1-mediated upregulation of Bax
-
Tanaka T, Hanafusa N, Ingelfinger JR, Ohse T, Fujita T, Nangaku M. Hypoxia induces apoptosis in SV40-immortalized rat proximal tubular cells through the mitochondrial pathways, devoid of HIF1-mediated upregulation of Bax. Biochem Biophys Res Commun 309: 222–231, 2003.
-
(2003)
Biochem Biophys Res Commun
, vol.309
, pp. 222-231
-
-
Tanaka, T.1
Hanafusa, N.2
Ingelfinger, J.R.3
Ohse, T.4
Fujita, T.5
Nangaku, M.6
-
123
-
-
26844537681
-
Hypoxia-inducible factor modulates tubular cell survival in cisplatin nephrotoxicity
-
Tanaka T, Kojima I, Ohse T, Inagi R, Miyata T, Ingelfinger JR, Fujita T, Nangaku M. Hypoxia-inducible factor modulates tubular cell survival in cisplatin nephrotoxicity. Am J Physiol Renal Physiol 289: F1123–F1133, 2005.
-
(2005)
Am J Physiol Renal Physiol
, vol.289
, pp. F1123-F1133
-
-
Tanaka, T.1
Kojima, I.2
Ohse, T.3
Inagi, R.4
Miyata, T.5
Ingelfinger, J.R.6
Fujita, T.7
Nangaku, M.8
-
124
-
-
84875698523
-
Angiogenesis and hypoxia in the kidney
-
Tanaka T, Nangaku M. Angiogenesis and hypoxia in the kidney. Nat Rev Nephrol 9: 211–222, 2013.
-
(2013)
Nat Rev Nephrol
, vol.9
, pp. 211-222
-
-
Tanaka, T.1
Nangaku, M.2
-
125
-
-
73849144012
-
The role of hypoxia, increased oxygen consumption, and hypoxia-inducible factor-1 alpha in progression of chronic kidney disease
-
Tanaka T, Nangaku M. The role of hypoxia, increased oxygen consumption, and hypoxia-inducible factor-1 alpha in progression of chronic kidney disease. Curr Opin Nephrol Hypertens 19: 43–50, 2010.
-
(2010)
Curr Opin Nephrol Hypertens
, vol.19
, pp. 43-50
-
-
Tanaka, T.1
Nangaku, M.2
-
126
-
-
84885154459
-
Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transacti-vator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxia-inducible genes in experimental CKD and uremia
-
Tanaka T, Yamaguchi J, Higashijima Y, Nangaku M. Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transacti-vator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxia-inducible genes in experimental CKD and uremia. FASEB J 27: 4059–4075, 2013.
-
(2013)
FASEB J
, vol.27
, pp. 4059-4075
-
-
Tanaka, T.1
Yamaguchi, J.2
Higashijima, Y.3
Nangaku, M.4
-
127
-
-
80655135477
-
Acute kidney injury episodes and chronic kidney disease risk in diabetes mellitus
-
Thakar CV, Christianson A, Himmelfarb J, Leonard AC. Acute kidney injury episodes and chronic kidney disease risk in diabetes mellitus. Clin J Am Soc Nephrol 6: 2567–2572, 2011.
-
(2011)
Clin J am Soc Nephrol
, vol.6
, pp. 2567-2572
-
-
Thakar, C.V.1
Christianson, A.2
Himmelfarb, J.3
Leonard, A.C.4
-
128
-
-
0032213236
-
The hypoxia-responsive transcription factor EPAS1 is essential for cat-echolamine homeostasis and protection against heart failure during embryonic development
-
Tian H, Hammer RE, Matsumoto AM, Russell DW, McKnight SL. The hypoxia-responsive transcription factor EPAS1 is essential for cat-echolamine homeostasis and protection against heart failure during embryonic development. Genes Dev 12: 3320–3324, 1998.
-
(1998)
Genes Dev
, vol.12
, pp. 3320-3324
-
-
Tian, H.1
Hammer, R.E.2
Matsumoto, A.M.3
Russell, D.W.4
McKnight, S.L.5
-
129
-
-
77951587507
-
Acute kidney injury: A springboard for progression in chronic kidney disease
-
Venkatachalam MA, Griffin KA, Lan R, Geng H, Saikumar P, Bidani AK. Acute kidney injury: a springboard for progression in chronic kidney disease. Am J Physiol Renal Physiol 298: F1078–F1094, 2010.
-
(2010)
Am J Physiol Renal Physiol
, vol.298
, pp. F1078-F1094
-
-
Venkatachalam, M.A.1
Griffin, K.A.2
Lan, R.3
Geng, H.4
Saikumar, P.5
Bidani, A.K.6
-
130
-
-
84861526917
-
Risk of chronic dialysis and death following acute kidney injury
-
Wald R, Quinn RR, Adhikari NK, Burns KE, Friedrich JO, Garg AX, Harel Z, Hladunewich MA, Luo J, Mamdani M, Perl J, Ray JG; University of Toronto Acute Kidney Injury Research Group. Risk of chronic dialysis and death following acute kidney injury. Am J Med 125: 585–593, 2012.
-
(2012)
Am J Med
, vol.125
, pp. 585-593
-
-
Wald, R.1
Quinn, R.R.2
Adhikari, N.K.3
Burns, K.E.4
Friedrich, J.O.5
Garg, A.X.6
Harel, Z.7
Hladunewich, M.A.8
Luo, J.9
Mamdani, M.10
Perl, J.11
Ray, J.G.12
-
131
-
-
70349155477
-
Chronicdialysis and death among survivors of acute kidney injury requiring dialysis
-
Wald R, Quinn RR, Luo J, Li P, Scales DC, Mamdani MM, Ray JG; University of Toronto Acute Kidney Injury Research Group. Chronic dialysis and death among survivors of acute kidney injury requiring dialysis. JAMA 302: 1179–1185, 2009.
-
(2009)
JAMA
, vol.302
, pp. 1179-1185
-
-
Wald, R.1
Quinn, R.R.2
Luo, J.3
Li, P.4
Scales, D.C.5
Mamdani, M.M.6
Ray, J.G.7
-
132
-
-
84860505643
-
The protective effect of prolyl-hydrox-ylase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment
-
Wang Z, Schley G, Türkoglu G, Burzlaff N, Amann KU, Willam C, Eckardt KU, Bernhardt WM. The protective effect of prolyl-hydrox-ylase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment. Nephrol Dial Transplant 27: 929–936, 2012.
-
(2012)
Nephrol Dial Transplant
, vol.27
, pp. 929-936
-
-
Wang, Z.1
Schley, G.2
Türkoglu, G.3
Burzlaff, N.4
Amann, K.U.5
Willam, C.6
Eckardt, K.U.7
Bernhardt, W.M.8
-
133
-
-
40449110083
-
HIF activation protects from acute kidney injury
-
Weidemann A, Bernhardt WM, Klanke B, Daniel C, Buchholz B, Câmpean V, Amann K, Warnecke C, Wiesener MS, Eckardt KU, Willam C. HIF activation protects from acute kidney injury. J Am Soc Nephrol 19: 486–494, 2008.
-
(2008)
J am Soc Nephrol
, vol.19
, pp. 486-494
-
-
Weidemann, A.1
Bernhardt, W.M.2
Klanke, B.3
Daniel, C.4
Buchholz, B.5
Câmpean, V.6
Amann, K.7
Warnecke, C.8
Wiesener, M.S.9
Eckardt, K.U.10
Willam, C.11
-
134
-
-
0034747030
-
Nephron pO2 and renal oxygen usage in the hypertensive rat kidney
-
Welch WJ, Baumgärtl H, Lübbers D, Wilcox CS. Nephron pO2 and renal oxygen usage in the hypertensive rat kidney. Kidney Int 59: 230–237, 2001.
-
(2001)
Kidney Int
, vol.59
, pp. 230-237
-
-
Welch, W.J.1
Baumgärtl, H.2
Lübbers, D.3
Wilcox, C.S.4
-
135
-
-
33748436376
-
Tissue oxygen and hemodynamics in renal medulla, cortex, and corticomedul-lary junction during hemorrhage-reperfusion
-
Whitehouse T, Stotz M, Taylor V, Stidwill R, Singer M. Tissue oxygen and hemodynamics in renal medulla, cortex, and corticomedul-lary junction during hemorrhage-reperfusion. Am J Physiol Renal Physiol 291: F647–F653, 2006.
-
(2006)
Am J Physiol Renal Physiol
, vol.291
, pp. F647-F653
-
-
Whitehouse, T.1
Stotz, M.2
Taylor, V.3
Stidwill, R.4
Singer, M.5
-
136
-
-
0037315337
-
Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs
-
Wiesener MS, Jürgensen JS, Rosenberger C, Scholze CK, Hörstrup JH, Warnecke C, Mandriota S, Bechmann I, Frei UA, Pugh CW, Ratcliffe PJ, Bachmann S, Maxwell PH, Eckardt KU. Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs. FASEB J 17: 271–273, 2003.
-
(2003)
FASEB J
, vol.17
, pp. 271-273
-
-
Wiesener, M.S.1
Jürgensen, J.S.2
Rosenberger, C.3
Scholze, C.K.4
Hörstrup, J.H.5
Warnecke, C.6
Mandriota, S.7
Bechmann, I.8
Frei, U.A.9
Pugh, C.W.10
Ratcliffe, P.J.11
Bachmann, S.12
Maxwell, P.H.13
Eckardt, K.U.14
-
137
-
-
77952174830
-
Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury
-
1p following 143
-
Yang L, Besschetnova TY, Brooks CR, Shah JV, Bonventre JV. Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury. Nat Med 16: 535–543, 1p following 143, 2010.
-
(2010)
Nat Med
, vol.16
, pp. 535-543
-
-
Yang, L.1
Besschetnova, T.Y.2
Brooks, C.R.3
Shah, J.V.4
Bonventre, J.V.5
-
138
-
-
84861651942
-
Noninvasive evaluation of renal oxygenation in diabetic nephropa-thy by BOLD-MRI
-
Yin WJ, Liu F, Li XM, Yang L, Zhao S, Huang ZX, Huang YQ, Liu RB. Noninvasive evaluation of renal oxygenation in diabetic nephropa-thy by BOLD-MRI. Eur J Radiol 81: 1426–1431, 2012.
-
(2012)
Eur J Radiol
, vol.81
, pp. 1426-1431
-
-
Yin, W.J.1
Liu, F.2
Li, X.M.3
Yang, L.4
Zhao, S.5
Huang, Z.X.6
Huang, Y.Q.7
Liu, R.B.8
-
139
-
-
84864612843
-
The balance of beneficial and deleterious effects of hypoxia-inducible factor activation by prolyl hydroxylase inhibitor in rat remnant kidney depends on the timing of administration
-
Yu X, Fang Y, Liu H, Zhu J, Zou J, Xu X, Jiang S, Ding X. The balance of beneficial and deleterious effects of hypoxia-inducible factor activation by prolyl hydroxylase inhibitor in rat remnant kidney depends on the timing of administration. Nephrol Dial Transplant 27: 3110–3119, 2012.
-
(2012)
Nephrol Dial Transplant
, vol.27
, pp. 3110-3119
-
-
Yu, X.1
Fang, Y.2
Liu, H.3
Zhu, J.4
Zou, J.5
Xu, X.6
Jiang, S.7
Ding, X.8
-
140
-
-
0345707657
-
Peritubular capillary loss after mouse acute nephrotoxicity correlates with down-regulation of vascular endothelial growth factor-A and hypoxia-inducible factor-1 alpha
-
Yuan HT, Li XZ, Pitera JE, Long DA, Woolf AS. Peritubular capillary loss after mouse acute nephrotoxicity correlates with down-regulation of vascular endothelial growth factor-A and hypoxia-inducible factor-1 alpha. Am J Pathol 163: 2289–2301, 2003.
-
(2003)
Am J Pathol
, vol.163
, pp. 2289-2301
-
-
Yuan, H.T.1
Li, X.Z.2
Pitera, J.E.3
Long, D.A.4
Woolf, A.S.5
-
141
-
-
84884548931
-
“Biologic memory” in response to acute kidney injury: Cytoresistance, toll-like receptor hyper-responsiveness and the onset of progressive renal disease
-
Zager RA. “Biologic memory” in response to acute kidney injury: cytoresistance, toll-like receptor hyper-responsiveness and the onset of progressive renal disease. Nephrol Dial Transplant 28: 1985–1993, 2013.
-
(2013)
Nephrol Dial Transplant
, vol.28
, pp. 1985-1993
-
-
Zager, R.A.1
-
142
-
-
66049156204
-
Renal ischemia-reperfusion injury upregulates histone-modifying enzyme systems and alters histone expression at proinflammatory/profibrotic genes
-
Zager RA, Johnson AC. Renal ischemia-reperfusion injury upregulates histone-modifying enzyme systems and alters histone expression at proinflammatory/profibrotic genes. Am J Physiol Renal Physiol 296: F1032–F1041, 2009.
-
(2009)
Am J Physiol Renal Physiol
, vol.296
, pp. F1032-F1041
-
-
Zager, R.A.1
Johnson, A.C.2
-
143
-
-
84885320788
-
Progressive endothe-lin-1 gene activation initiates chronic/end-stage renal disease following experimental ischemic/reperfusion injury
-
Zager RA, Johnson AC, Andress D, Becker K. Progressive endothe-lin-1 gene activation initiates chronic/end-stage renal disease following experimental ischemic/reperfusion injury. Kidney Int 84: 703–712, 2013.
-
(2013)
Kidney Int
, vol.84
, pp. 703-712
-
-
Zager, R.A.1
Johnson, A.C.2
Ress, D.3
Becker, K.4
-
144
-
-
82755172460
-
Acute unilateral ischemic renal injury induces progressive renal inflammation, lipid accumulation, his-tone modification, and “end-stage” kidney disease
-
Zager RA, Johnson AC, Becker K. Acute unilateral ischemic renal injury induces progressive renal inflammation, lipid accumulation, his-tone modification, and “end-stage” kidney disease. Am J Physiol Renal Physiol 301: F1334–F1345, 2011.
-
(2011)
Am J Physiol Renal Physiol
, vol.301
, pp. F1334-F1345
-
-
Zager, R.A.1
Johnson, A.C.2
Becker, K.3
|