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Volumn 301, Issue 6, 2011, Pages

Acute unilateral ischemic renal injury induces progressive renal inflammation, lipid accumulation, histone modification, and "end-stage" kidney disease

Author keywords

Acute kidney injury; Progressive renal disease

Indexed keywords

CHOLESTEROL; COLLAGEN TYPE 3; HEME OXYGENASE 1; INTERLEUKIN 10; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; TRANSFORMING GROWTH FACTOR BETA1; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

EID: 82755172460     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00431.2011     Document Type: Article
Times cited : (144)

References (58)
  • 1
    • 33745099273 scopus 로고    scopus 로고
    • Histone deacetylation: An important mechanism in inflammatory lung diseases (Review)
    • Adcock IM, Ito K, Barnes PJ. Histone deacetylation: an important mechanism in inflammatory lung diseases (Review). COPD 2: 445-455, 2005.
    • (2005) COPD , vol.2 , pp. 445-455
    • Adcock, I.M.1    Ito, K.2    Barnes, P.J.3
  • 3
    • 34247609488 scopus 로고    scopus 로고
    • Pathophysiology of acute kidney injury: Roles of potential inhibitors of inflammation (Review)
    • Bonventre JV. Pathophysiology of acute kidney injury: roles of potential inhibitors of inflammation (Review). Contrib Nephrol 156: 39-46, 2007.
    • (2007) Contrib Nephrol , vol.156 , pp. 39-46
    • Bonventre, J.V.1
  • 4
    • 77956924080 scopus 로고    scopus 로고
    • Toxicoepigenetic alteration of the kidney injury molecule 1 gene in gentamicin-exposed rat kidney
    • Chen F, Smith R, Gu YZ, Collins ND, Nioi P. Toxicoepigenetic alteration of the kidney injury molecule 1 gene in gentamicin-exposed rat kidney. Toxicol Sci 117: 375-380, 2010.
    • (2010) Toxicol Sci , vol.117 , pp. 375-380
    • Chen, F.1    Smith, R.2    Gu, Y.Z.3    Collins, N.D.4    Nioi, P.5
  • 5
    • 79951671843 scopus 로고    scopus 로고
    • Nitric oxide (NO) is associated with gentamicin (GENTA) nephrotoxicity and the renal function recovery after suspension of GENTA treatment in rats
    • Christo JS, Rodrigues AM, Mouro MG, Cenedeze MA, Simoes MJ, Schor N, Higa EM. Nitric oxide (NO) is associated with gentamicin (GENTA) nephrotoxicity and the renal function recovery after suspension of GENTA treatment in rats. Nitric Oxide 24: 77-83, 2011.
    • (2011) Nitric Oxide , vol.24 , pp. 77-83
    • Christo, J.S.1    Rodrigues, A.M.2    Mouro, M.G.3    Cenedeze, M.A.4    Simoes, M.J.5    Schor, N.6    Higa, E.M.7
  • 6
    • 79954426215 scopus 로고    scopus 로고
    • Biomarkers for the early detection of acute kidney injury
    • Devarajan P. Biomarkers for the early detection of acute kidney injury. Curr Opin Pediatr 23: 194-200, 2011.
    • (2011) Curr Opin Pediatr , vol.23 , pp. 194-200
    • Devarajan, P.1
  • 7
    • 0018834623 scopus 로고
    • Enhanced recovery from postischemic acute renal failure. Micropuncture studies in the rat
    • Finn WF. Enhanced recovery from postischemic acute renal failure. Micropuncture studies in the rat. Circ Res 46: 440-448, 1980.
    • (1980) Circ Res , vol.46 , pp. 440-448
    • Finn, W.F.1
  • 8
    • 4243553019 scopus 로고
    • Recovery from acute renal failure
    • Brenner BM and Lazarus JM. New York: Churchill Livingstone
    • Finn WF. Recovery from acute renal failure. In: Acute Renal Failure, edited by Brenner BM and Lazarus JM. New York: Churchill Livingstone, 1988, p. 875-918.
    • (1988) Acute Renal Failure , pp. 875-918
    • Finn, W.F.1
  • 9
    • 0018697595 scopus 로고
    • Recovery from postischemic acute renal failure in the rat
    • Finn WF, Chevalier RL. Recovery from postischemic acute renal failure in the rat. Kidney Int 16: 113-123, 1979.
    • (1979) Kidney Int , vol.16 , pp. 113-123
    • Finn, W.F.1    Chevalier, R.L.2
  • 10
    • 0021323119 scopus 로고
    • Attenuation of injury due to unilateral renal ischemia: Delayed effects of contralateral nephrectomy
    • Finn WF, Fernandez-Repollet E, Goldfarb D, Iaina A, Eliahou HE. Attenuation of injury due to unilateral renal ischemia: delayed effects of contralateral nephrectomy. J Lab Clin Med 103: 193-203, 1984.
    • (1984) J Lab Clin Med , vol.103 , pp. 193-203
    • Finn, W.F.1    Fernandez-Repollet, E.2    Goldfarb, D.3    Iaina, A.4    Eliahou, H.E.5
  • 12
    • 59149088542 scopus 로고    scopus 로고
    • Heme oxygenase and renal disease (Review)
    • Jarmi T, Agarwal A. Heme oxygenase and renal disease (Review). Curr Hypertens Rep 11: 56-62, 2009.
    • (2009) Curr Hypertens Rep , vol.11 , pp. 56-62
    • Jarmi, T.1    Agarwal, A.2
  • 13
    • 23044471901 scopus 로고    scopus 로고
    • Triglyceride accumulation in injured renal tubular cells: Alterations in both synthetic and catabolic pathways
    • Johnson AC, Stahl A, Zager RA. Triglyceride accumulation in injured renal tubular cells: alterations in both synthetic and catabolic pathways. Kidney Int 67: 2196-2209, 2005.
    • (2005) Kidney Int , vol.67 , pp. 2196-2209
    • Johnson, A.C.1    Stahl, A.2    Zager, R.A.3
  • 14
    • 66449113034 scopus 로고    scopus 로고
    • Renal mass reduction results in accumulation of lipids and dysregulation of lipid regulatory proteins in the remnant kidney
    • Kim HJ, Moradi H, Yuan J, Norris K, Vaziri ND. Renal mass reduction results in accumulation of lipids and dysregulation of lipid regulatory proteins in the remnant kidney. Am J Physiol Renal Physiol 296: F1297-F1306, 2009.
    • (2009) Am J Physiol Renal Physiol , vol.296
    • Kim, H.J.1    Moradi, H.2    Yuan, J.3    Norris, K.4    Vaziri, N.D.5
  • 15
    • 0019765136 scopus 로고
    • Time of death, recovery of renal function, development of chronic renal failure and need for chronic hemodialysis in patients with acute tubular necrosis
    • Kjellstrand CM, Ebben J, Davin T. Time of death, recovery of renal function, development of chronic renal failure and need for chronic hemodialysis in patients with acute tubular necrosis. Trans Am Soc Artif Intern Organs 27: 45-50, 1981.
    • (1981) Trans Am Soc Artif Intern Organs , vol.27 , pp. 45-50
    • Kjellstrand, C.M.1    Ebben, J.2    Davin, T.3
  • 17
    • 70349633543 scopus 로고
    • Effects of temporary interruption of renal circulation in rats
    • Koletsky S. Effects of temporary interruption of renal circulation in rats. AMA Arch Pathol 58: 592-603, 1954.
    • (1954) AMA Arch Pathol , vol.58 , pp. 592-603
    • Koletsky, S.1
  • 19
    • 81955168062 scopus 로고    scopus 로고
    • Acute Kidney Injury Network definition of contrast-induced nephropathy in the crically ill: Incidence and outcome
    • prepublished online July 5, doi:10.1016/j.crci2011.05.010, 9999
    • Lakhal K, Ehrmann S, Chaari A, Laissy JP, Régnier B, Wolff M, Pajot O. Acute Kidney Injury Network definition of contrast-induced nephropathy in the crically ill: incidence and outcome. J Crit Care prepublished online July 5, 2011; doi:10.1016/j.crci2011.05.010, 9999.
    • (2011) J Crit Care
    • Lakhal, K.1    Ehrmann, S.2    Chaari, A.3    Laissy, J.P.4    Régnier, B.5    Wolff, M.6    Pajot, O.7
  • 22
    • 70349673306 scopus 로고    scopus 로고
    • Dialysis-requiring acute renal failure increases the risk of progressive chronic kidney disease
    • Lo LJ, Go AS, Chertow GM, McCulloch CE, Fan D, Ordonez JD, Hsu CY. Dialysis-requiring acute renal failure increases the risk of progressive chronic kidney disease. Kidney Int 76: 893-899, 2009.
    • (2009) Kidney Int , vol.76 , pp. 893-899
    • Lo, L.J.1    Go, A.S.2    Chertow, G.M.3    McCulloch, C.E.4    Fan, D.5    Ordonez, J.D.6    Hsu, C.Y.7
  • 23
    • 0028921549 scopus 로고
    • Advantages of Sirius Red staining for quantitative morphometric collagen measurements in lungs
    • Malkusch W, Rehn B, Bruch J. Advantages of Sirius Red staining for quantitative morphometric collagen measurements in lungs. Exp Lung Res 21: 67-77, 1995.
    • (1995) Exp Lung Res , vol.21 , pp. 67-77
    • Malkusch, W.1    Rehn, B.2    Bruch, J.3
  • 25
    • 32844466263 scopus 로고    scopus 로고
    • Fibrate prevents cisplatininduced proximal tubule cell death
    • Nagothu KK, Bhatt R, Kaushal GP, Portilla D. Fibrate prevents cisplatininduced proximal tubule cell death. Kidney Int 68: 2680-2693, 2005.
    • (2005) Kidney Int , vol.68 , pp. 2680-2693
    • Nagothu, K.K.1    Bhatt, R.2    Kaushal, G.P.3    Portilla, D.4
  • 26
    • 58249106755 scopus 로고    scopus 로고
    • Renal ischemia-induced cholesterol loading: Transcription factor recruitment and chromatin remodeling along the HMG CoA reductase gene
    • Naito M, Bomsztyk K, Zager RA. Renal ischemia-induced cholesterol loading: transcription factor recruitment and chromatin remodeling along the HMG CoA reductase gene. Am J Pathol 174: 54-62, 2009.
    • (2009) Am J Pathol , vol.174 , pp. 54-62
    • Naito, M.1    Bomsztyk, K.2    Zager, R.A.3
  • 27
    • 68049131578 scopus 로고    scopus 로고
    • BRG1 increases transcription of proinflammatory genes in renal ischemia
    • Naito M, Zager RA, Bomsztyk K. BRG1 increases transcription of proinflammatory genes in renal ischemia. J Am Soc Nephrol 20: 1787-1796, 2009.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 1787-1796
    • Naito, M.1    Zager, R.A.2    Bomsztyk, K.3
  • 28
    • 33746552172 scopus 로고    scopus 로고
    • Heme oxygenase-1: A provenance for cytoprotective pathways in the kidney and other tissues (Review)
    • Nath KA. Heme oxygenase-1: a provenance for cytoprotective pathways in the kidney and other tissues (Review). Kidney Int 70: 432-443, 2006.
    • (2006) Kidney Int , vol.70 , pp. 432-443
    • Nath, K.A.1
  • 29
    • 0034075616 scopus 로고    scopus 로고
    • Renal response to repetitive exposure to heme proteins: Chronic injury induced by an acute insult
    • Nath KA, Croatt AJ, Haggard JJ, Grande JP. Renal response to repetitive exposure to heme proteins: chronic injury induced by an acute insult. Kidney Int 57: 2423-2433, 2000.
    • (2000) Kidney Int , vol.57 , pp. 2423-2433
    • Nath, K.A.1    Croatt, A.J.2    Haggard, J.J.3    Grande, J.P.4
  • 30
    • 79961203984 scopus 로고    scopus 로고
    • Genetic deficiency of Smad3 protects against murine ischemic acute kidney injury
    • prepublished online April 27, doi:10.1152/ajprenal.00162.2011,9999
    • Nath KA, Croatt AJ, Warner GM, Grande JP. Genetic deficiency of Smad3 protects against murine ischemic acute kidney injury. Am J Physiol Renal Physiol prepublished online April 27, 2011; doi:10.1152/ajprenal.00162.2011,9999.
    • (2011) Am J Physiol Renal Physiol
    • Nath, K.A.1    Croatt, A.J.2    Warner, G.M.3    Grande, J.P.4
  • 31
    • 70449632876 scopus 로고    scopus 로고
    • Recovery from renal ischemia-reperfusion injury is associated with altered renal hemodynamics, blunted pressure natriuresis, and sodiumsensitive hypertension
    • Pechman KR, De Miguel C, Lund H, Leonard EC, Basile DP, Mattson DL. Recovery from renal ischemia-reperfusion injury is associated with altered renal hemodynamics, blunted pressure natriuresis, and sodiumsensitive hypertension. Am J Physiol Regul Integr Comp Physiol 297: R1358-R1363, 2009.
    • (2009) Am J Physiol Regul Integr Comp Physiol , vol.297
    • Pechman, K.R.1    de Miguel, C.2    Lund, H.3    Leonard, E.C.4    Basile, D.P.5    Mattson, D.L.6
  • 35
    • 0038509036 scopus 로고    scopus 로고
    • Lipotoxicity: When tissues overeat (Review)
    • Schaffer JE. Lipotoxicity: when tissues overeat (Review). Curr Opin Lipid 14: 281-287, 2003.
    • (2003) Curr Opin Lipid , vol.14 , pp. 281-287
    • Schaffer, J.E.1
  • 36
    • 79953175649 scopus 로고    scopus 로고
    • Pathophysiology of ischemic acute kidney injury
    • Sharfuddin AA, Molitoris BA. Pathophysiology of ischemic acute kidney injury. Nature Rev Nephrol 7: 189-200, 2011.
    • (2011) Nature Rev Nephrol , vol.7 , pp. 189-200
    • Sharfuddin, A.A.1    Molitoris, B.A.2
  • 38
    • 78049500964 scopus 로고    scopus 로고
    • Endogenous IL-10 attenuates cisplatin nephrotoxicity: Role of dendritic cells
    • Tadagavadi RK, Reeves WB. Endogenous IL-10 attenuates cisplatin nephrotoxicity: role of dendritic cells. J Immunol 185: 4904-4911, 2010.
    • (2010) J Immunol , vol.185 , pp. 4904-4911
    • Tadagavadi, R.K.1    Reeves, W.B.2
  • 43
    • 33750217236 scopus 로고    scopus 로고
    • Lipotoxicity (Review)
    • Weinberg JM. Lipotoxicity (Review). Kidney Int 70: 1560-1566, 2006.
    • (2006) Kidney Int , vol.70 , pp. 1560-1566
    • Weinberg, J.M.1
  • 46
    • 60549095619 scopus 로고    scopus 로고
    • Uremia induces proximal tubular cytoresistance and heme oxygenase-1 expression in the absence of acute kidney injury
    • Zager RA. Uremia induces proximal tubular cytoresistance and heme oxygenase-1 expression in the absence of acute kidney injury. Am J Physiol Renal Physiol 296: F362-F368, 2009.
    • (2009) Am J Physiol Renal Physiol , vol.296
    • Zager, R.A.1
  • 47
    • 0035430539 scopus 로고    scopus 로고
    • Renal cholesterol accumulation: A durable response after acute and subacute renal insults
    • Zager RA, Andoh T, Bennett WM. Renal cholesterol accumulation: a durable response after acute and subacute renal insults. Am J Pathol 159: 743-752, 2001.
    • (2001) Am J Pathol , vol.159 , pp. 743-752
    • Zager, R.A.1    Andoh, T.2    Bennett, W.M.3
  • 48
    • 0032746959 scopus 로고    scopus 로고
    • Increased proximal tubular cholesterol content: Implications for cell injury and acquired cytoresistance
    • Zager RA, Burkhart KM, Johnson ACM, Sacks BM. Increased proximal tubular cholesterol content: implications for cell injury and "acquired cytoresistance". Kidney Int 56: 1788-1797, 1999.
    • (1999) Kidney Int , vol.56 , pp. 1788-1797
    • Zager, R.A.1    Burkhart, K.M.2    Johnson, A.C.M.3    Sacks, B.M.4
  • 49
    • 33645526689 scopus 로고    scopus 로고
    • Acute nephrotoxic and obstructive injury primes the kidney to endotoxin-driven cytokine/chemokine production
    • Zager RA, Johnson AC, Hanson SY, Lund S. Acute nephrotoxic and obstructive injury primes the kidney to endotoxin-driven cytokine/chemokine production. Kidney Int 69: 1181-1188, 2006.
    • (2006) Kidney Int , vol.69 , pp. 1181-1188
    • Zager, R.A.1    Johnson, A.C.2    Hanson, S.Y.3    Lund, S.4
  • 50
    • 0038645852 scopus 로고    scopus 로고
    • Acute tubular injury causes dysregulation of cellular cholesterol transport proteins
    • Zager RA, Johnson AC, Hanson SY, Shah VO. Acute tubular injury causes dysregulation of cellular cholesterol transport proteins. Am J Pathol 163: 313-320, 2003.
    • (2003) Am J Pathol , vol.163 , pp. 313-320
    • Zager, R.A.1    Johnson, A.C.2    Hanson, S.Y.3    Shah, V.O.4
  • 51
    • 33947141537 scopus 로고    scopus 로고
    • "Endotoxin tolerance": TNF-alpha hyperreactivity and tubular cytoresistance in a renal cholesterol loading state
    • Zager RA, Johnson AC, Lund S. "Endotoxin tolerance": TNF-alpha hyperreactivity and tubular cytoresistance in a renal cholesterol loading state. Kidney Int 71: 496-503, 2007.
    • (2007) Kidney Int , vol.71 , pp. 496-503
    • Zager, R.A.1    Johnson, A.C.2    Lund, S.3
  • 52
    • 66049156204 scopus 로고    scopus 로고
    • Renal ischemia-reperfusion injury upregulates histone-modifying enzyme systems and alters histone expression at proinflammatory/ profibrotic genes
    • Zager RA, Johnson ACM. Renal ischemia-reperfusion injury upregulates histone-modifying enzyme systems and alters histone expression at proinflammatory/ profibrotic genes. Am J Physiol Renal Physiol 296: F1032-F1041, 2009.
    • (2009) Am J Physiol Renal Physiol , vol.296
    • Zager, R.A.1    Johnson, A.C.M.2
  • 53
    • 77649158373 scopus 로고    scopus 로고
    • Progressive histone alterations and proinflammatory gene activation: Consequences of heme protein/iron-mediated proximal tubule injury
    • Zager RA, Johnson ACM. Progressive histone alterations and proinflammatory gene activation: consequences of heme protein/iron-mediated proximal tubule injury. Am J Physiol Renal Physiol 298: F827-F837, 2010.
    • (2010) Am J Physiol Renal Physiol , vol.298
    • Zager, R.A.1    Johnson, A.C.M.2
  • 54
    • 10944237672 scopus 로고    scopus 로고
    • Renal tubular triglyercide accumulation following endotoxic, toxic, and ischemic injury
    • Zager RA, Johnson ACM, Hanson SY. Renal tubular triglyercide accumulation following endotoxic, toxic, and ischemic injury. Kidney Int 67: 111-121, 2005.
    • (2005) Kidney Int , vol.67 , pp. 111-121
    • Zager, R.A.1    Johnson, A.C.M.2    Hanson, S.Y.3
  • 55
    • 70349645531 scopus 로고    scopus 로고
    • Uremia impacts renal inflammatory cytokine gene expression in the setting of experimental acute kidney injury
    • Zager RA, Johnson ACM, Lund S. Uremia impacts renal inflammatory cytokine gene expression in the setting of experimental acute kidney injury. Am J Physiol Renal Physiol 297: F961-F970, 2009.
    • (2009) Am J Physiol Renal Physiol , vol.297
    • Zager, R.A.1    Johnson, A.C.M.2    Lund, S.3
  • 56
    • 0036966284 scopus 로고    scopus 로고
    • The mevalonate pathway during acute tubular injury: Selected determinants and consequences
    • Zager RA, Shah VO, Shah HV, Zager PG, Johnson AC, Hanson S. The mevalonate pathway during acute tubular injury: selected determinants and consequences. Am J Pathol 161: 681-692, 2002.
    • (2002) Am J Pathol , vol.161 , pp. 681-692
    • Zager, R.A.1    Shah, V.O.2    Shah, H.V.3    Zager, P.G.4    Johnson, A.C.5    Hanson, S.6
  • 57
    • 0033916957 scopus 로고    scopus 로고
    • Plasma membrane cholesterol: A critical determinant of cellular energetics and tubular resistance to attack
    • Zager RA, Johnson A, Anderson K. Plasma membrane cholesterol: a critical determinant of cellular energetics and tubular resistance to attack. Kidney Int 58: 193-205, 2000.
    • (2000) Kidney Int , vol.58 , pp. 193-205
    • Zager, R.A.1    Johnson, A.2    Anderson, K.3


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