-
1
-
-
0025356654
-
Mitochondrial injury: An early event in cisplatin toxicity to renal proximal tubules
-
Brady HR, Kone BC, Stromski ME, Zeidel ML, Giebisch G, and Gullans SR. Mitochondrial injury: an early event in cisplatin toxicity to renal proximal tubules. Am J Physiol Renal Fluid Electrolyte Physiol 258: F1181-F1187, 1990.
-
(1990)
Am J Physiol Renal Fluid Electrolyte Physiol
, vol.258
-
-
Brady, H.R.1
Kone, B.C.2
Stromski, M.E.3
Zeidel, M.L.4
Giebisch, G.5
Gullans, S.R.6
-
2
-
-
0344608877
-
Dominant-negative hypoxia-inducible factor-1α reduces tumorigenicity of pancreatic cancer cells through the suppression of glucose metabolism
-
Chen J, Zhao S, Nakada K, Kuge Y, Tamaki N, Okada F, Wang J, Shindo M, Higashino F, Takeda K, Asaka M, Katoh H, Sugiyama T, Hosokawa M, and Kobayashi M. Dominant-negative hypoxia-inducible factor-1α reduces tumorigenicity of pancreatic cancer cells through the suppression of glucose metabolism. Am J Pathol 162: 1283-1291, 2003.
-
(2003)
Am J Pathol
, vol.162
, pp. 1283-1291
-
-
Chen, J.1
Zhao, S.2
Nakada, K.3
Kuge, Y.4
Tamaki, N.5
Okada, F.6
Wang, J.7
Shindo, M.8
Higashino, F.9
Takeda, K.10
Asaka, M.11
Katoh, H.12
Sugiyama, T.13
Hosokawa, M.14
Kobayashi, M.15
-
3
-
-
0037423948
-
HIF-1α is essential for myeloid cell-mediated inflammation
-
Cramer T, Yamanishi Y, Clausen BE, Forster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, and Johnson RS. HIF-1α is essential for myeloid cell-mediated inflammation. Cell 112: 645-657, 2003.
-
(2003)
Cell
, vol.112
, pp. 645-657
-
-
Cramer, T.1
Yamanishi, Y.2
Clausen, B.E.3
Forster, I.4
Pawlinski, R.5
Mackman, N.6
Haase, V.H.7
Jaenisch, R.8
Corr, M.9
Nizet, V.10
Firestein, G.S.11
Gerber, H.P.12
Ferrara, N.13
Johnson, R.S.14
-
4
-
-
0018859587
-
Mechanism of cis-platinum nephrotoxicity. II. Morphologic observations
-
Dobyan DC, Levi J, Jacobs C, Kosek J, and Weiner MW. Mechanism of cis-platinum nephrotoxicity. II. Morphologic observations. J Pharmacol Exp Ther 213: 551-556, 1980.
-
(1980)
J Pharmacol Exp Ther
, vol.213
, pp. 551-556
-
-
Dobyan, D.C.1
Levi, J.2
Jacobs, C.3
Kosek, J.4
Weiner, M.W.5
-
5
-
-
0042845994
-
Apoptosis-resistance of hypoxic cells: Multiple factors involved and a role for IAP-2
-
Dong Z, Wang JZ, Yu F, and Venkatachalam MA. Apoptosis-resistance of hypoxic cells: multiple factors involved and a role for IAP-2. Am J Pathol 163: 663-671, 2003.
-
(2003)
Am J Pathol
, vol.163
, pp. 663-671
-
-
Dong, Z.1
Wang, J.Z.2
Yu, F.3
Venkatachalam, M.A.4
-
6
-
-
0038693518
-
Role of hypoxia in the pathogenesis of renal disease
-
Eckardt KU, Rosenberger C, Jurgensen JS, and Wiesener MS. Role of hypoxia in the pathogenesis of renal disease. Blood Purif 21: 253-257, 2003.
-
(2003)
Blood Purif
, vol.21
, pp. 253-257
-
-
Eckardt, K.U.1
Rosenberger, C.2
Jurgensen, J.S.3
Wiesener, M.S.4
-
7
-
-
17944375360
-
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
-
Epstein AC, Gleadle JM, McNeill LA, Hewitson KS, O'Rourke J, Mole DR, Mukherji M, Metzen E, Wilson MI, Dhanda A, Tian YM, Masson N, Hamilton DL, Jaakkola P, Barstead R, Hodgkin J, Maxwell PH, Pugh CW, Schofield CJ, and Ratcliffe PJ. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 107: 43-54, 2001.
-
(2001)
Cell
, vol.107
, pp. 43-54
-
-
Epstein, A.C.1
Gleadle, J.M.2
McNeill, L.A.3
Hewitson, K.S.4
O'Rourke, J.5
Mole, D.R.6
Mukherji, M.7
Metzen, E.8
Wilson, M.I.9
Dhanda, A.10
Tian, Y.M.11
Masson, N.12
Hamilton, D.L.13
Jaakkola, P.14
Barstead, R.15
Hodgkin, J.16
Maxwell, P.H.17
Pugh, C.W.18
Schofield, C.J.19
Ratcliffe, P.J.20
more..
-
8
-
-
0034037110
-
Is there a common mechanism for the progression of different types of renal diseases other than proteinuria? Towards the unifying theme of chronic hypoxia
-
Fine LG, Bandyopadhay D, and Norman JT. Is there a common mechanism for the progression of different types of renal diseases other than proteinuria? Towards the unifying theme of chronic hypoxia. Kidney Int Suppl 75: S22-26, 2000.
-
(2000)
Kidney Int Suppl
, vol.75
-
-
Fine, L.G.1
Bandyopadhay, D.2
Norman, J.T.3
-
10
-
-
0033035228
-
Rat proximal tubule cell line transformed with origin-defective SV40 DNA: Autocrine ANG II feedback
-
Ingelfinger JR, Jung F, Diamant D, Haveran L, Lee E, Brem A, and Tang SS. Rat proximal tubule cell line transformed with origin-defective SV40 DNA: autocrine ANG II feedback. Am J Physiol Renal Physiol 276: F218-F227, 1999.
-
(1999)
Am J Physiol Renal Physiol
, vol.276
-
-
Ingelfinger, J.R.1
Jung, F.2
Diamant, D.3
Haveran, L.4
Lee, E.5
Brem, A.6
Tang, S.S.7
-
11
-
-
0037108807
-
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
-
Ivan M, Haberberger T, Gervasi DC, Michelson KS, Gunzler V, Kondo K, Yang H, Sorokina I, Conaway RC, Conaway JW, and Kaelin WG Jr. Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor. Proc Natl Acad Sci USA 99: 13459-13464, 2002.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13459-13464
-
-
Ivan, M.1
Haberberger, T.2
Gervasi, D.C.3
Michelson, K.S.4
Gunzler, V.5
Kondo, K.6
Yang, H.7
Sorokina, I.8
Conaway, R.C.9
Conaway, J.W.10
Kaelin Jr., W.G.11
-
12
-
-
0035917313
-
2 sensing
-
2 sensing. Science 292: 464-468, 2001.
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin Jr., W.G.10
-
13
-
-
0035917808
-
2-regulated prolyl hydroxylation
-
2-regulated prolyl hydroxylation. Science 292: 468-472, 2001.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
14
-
-
0033947341
-
Vascular endothelial growth factor is a survival factor for renal tubular epithelial cells
-
Kanellis J, Fraser S, Katerelos M, and Power DA. Vascular endothelial growth factor is a survival factor for renal tubular epithelial cells. Am J Physiol Renal Physiol 278: F905-F915, 2000.
-
(2000)
Am J Physiol Renal Physiol
, vol.278
-
-
Kanellis, J.1
Fraser, S.2
Katerelos, M.3
Power, D.A.4
-
15
-
-
0036191166
-
Role of the microvascular endothelium in progressive renal disease
-
Kang DH, Kanellis J, Hugo C, Truong L, Anderson S, Kerjaschki D, Schreiner GF, and Johnson RJ. Role of the microvascular endothelium in progressive renal disease. J Am Soc Nephrol 13: 806-816, 2002.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 806-816
-
-
Kang, D.H.1
Kanellis, J.2
Hugo, C.3
Truong, L.4
Anderson, S.5
Kerjaschki, D.6
Schreiner, G.F.7
Johnson, R.J.8
-
16
-
-
0029039195
-
Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia
-
Levy AP, Levy NS, Wegner S, and Goldberg MA. Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia. J Biol Chem 270: 13333-13340, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 13333-13340
-
-
Levy, A.P.1
Levy, N.S.2
Wegner, S.3
Goldberg, M.A.4
-
17
-
-
0031423816
-
Intrarenal oxygen tension measured by a modified clark electrode at normal and low blood pressure and after injection of x-ray contrast media
-
Liss P, Nygren A, Revsbech NP, and Ulfendahl HR. Intrarenal oxygen tension measured by a modified clark electrode at normal and low blood pressure and after injection of x-ray contrast media. Pflügers Arch 434: 705-711, 1997.
-
(1997)
Pflügers Arch
, vol.434
, pp. 705-711
-
-
Liss, P.1
Nygren, A.2
Revsbech, N.P.3
Ulfendahl, H.R.4
-
18
-
-
0037530588
-
Induction of renoprotective gene expression by cobalt ameliorates ischemic injury of the kidney in rats
-
Matsumoto M, Makino Y, Tanaka T, Tanaka H, Ishizaka N, Noiri E, Fujita T, and Nangaku M. Induction of renoprotective gene expression by cobalt ameliorates ischemic injury of the kidney in rats. J Am Soc Nephrol 14: 1825-1832, 2003.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 1825-1832
-
-
Matsumoto, M.1
Makino, Y.2
Tanaka, T.3
Tanaka, H.4
Ishizaka, N.5
Noiri, E.6
Fujita, T.7
Nangaku, M.8
-
19
-
-
4644255532
-
Hypoxia and tubulointerstitial injury: A final common pathway to end-stage renal failure
-
Nangaku M. Hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure. Nephron Exp Nephrol 98: e8-12, 2004.
-
(2004)
Nephron Exp Nephrol
, vol.98
-
-
Nangaku, M.1
-
20
-
-
0036206569
-
Cisplatin induces apoptosis in LLC-PK1 cells via activation of mitochondrial pathways
-
Park MS, De Leon M, and Devarajan P. Cisplatin induces apoptosis in LLC-PK1 cells via activation of mitochondrial pathways. J Am Soc Nephrol 13: 858-865, 2002.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 858-865
-
-
Park, M.S.1
De Leon, M.2
Devarajan, P.3
-
21
-
-
0042932770
-
Cellular responses to hypoxia after renal segmental infarction
-
Rosenberger C, Griethe W, Gruber G, Wiesener M, Frei U, Bachmann S, and Eckardt KU. Cellular responses to hypoxia after renal segmental infarction. Kidney Int 64: 874-886, 2003.
-
(2003)
Kidney Int
, vol.64
, pp. 874-886
-
-
Rosenberger, C.1
Griethe, W.2
Gruber, G.3
Wiesener, M.4
Frei, U.5
Bachmann, S.6
Eckardt, K.U.7
-
22
-
-
18444380862
-
Expression of hypoxia-inducible factor-1α and -2α in hypoxic and ischemic rat kidneys
-
Rosenberger C, Mandriota S, Jurgensen JS, Wiesener MS, Horstrup JH, Frei U, Ratcliffe PJ, Maxwell PH, Bachmann S, and Eckardt KU. Expression of hypoxia-inducible factor-1α and -2α in hypoxic and ischemic rat kidneys. J Am Soc Nephrol 13: 1721-1732, 2002.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 1721-1732
-
-
Rosenberger, C.1
Mandriota, S.2
Jurgensen, J.S.3
Wiesener, M.S.4
Horstrup, J.H.5
Frei, U.6
Ratcliffe, P.J.7
Maxwell, P.H.8
Bachmann, S.9
Eckardt, K.U.10
-
23
-
-
0022627453
-
Glucose metabolism in renal tubular function
-
Ross BD, Espinal J, and Silva P. Glucose metabolism in renal tubular function. Kidney Int 29: 54-67, 1986.
-
(1986)
Kidney Int
, vol.29
, pp. 54-67
-
-
Ross, B.D.1
Espinal, J.2
Silva, P.3
-
24
-
-
4644260710
-
Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress
-
Salnikow K, Donald SP, Bruick RK, Zhitkovich A, Phang JM, and Kasprzak KS. Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress. J Biol Chem 279: 40337-40344, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 40337-40344
-
-
Salnikow, K.1
Donald, S.P.2
Bruick, R.K.3
Zhitkovich, A.4
Phang, J.M.5
Kasprzak, K.S.6
-
25
-
-
3543097510
-
Erythropoietin protects the kidney against the injury and dysfunction caused by ischemia-reperfusion
-
Sharples EJ, Patel N, Brown P, Stewart K, Mota-Philipe H, Sheaff M, Kieswich J, Allen D, Harwood S, Raftery M, Thiemermann C, and Yaqoob MM. Erythropoietin protects the kidney against the injury and dysfunction caused by ischemia-reperfusion. J Am Soc Nephrol 15: 2115-2124, 2004.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 2115-2124
-
-
Sharples, E.J.1
Patel, N.2
Brown, P.3
Stewart, K.4
Mota-Philipe, H.5
Sheaff, M.6
Kieswich, J.7
Allen, D.8
Harwood, S.9
Raftery, M.10
Thiemermann, C.11
Yaqoob, M.M.12
-
26
-
-
0034076763
-
Heme oxygenase-1 gene ablation or expression modulates cisplatin-induced renal tubular apoptosis
-
Shiraishi F, Curtis LM, Truong L, Poss K, Visner GA, Madsen K, Nick HS, and Agarwal A. Heme oxygenase-1 gene ablation or expression modulates cisplatin-induced renal tubular apoptosis. Am J Physiol Renal Physiol 278: F726-F736, 2000.
-
(2000)
Am J Physiol Renal Physiol
, vol.278
-
-
Shiraishi, F.1
Curtis, L.M.2
Truong, L.3
Poss, K.4
Visner, G.A.5
Madsen, K.6
Nick, H.S.7
Agarwal, A.8
-
27
-
-
0042235096
-
Hypoxia induces apoptosis in SV40-immortalized rat proximal tubular cells through the mitochondrial pathways, devoid of HIF1-mediated upregulation of Bax
-
Tanaka T, Hanafusa N, Ingelfinger JR, Ohse T, Fujita T, and Nangaku M. Hypoxia induces apoptosis in SV40-immortalized rat proximal tubular cells through the mitochondrial pathways, devoid of HIF1-mediated upregulation of Bax. Biochem Biophys Res Commun 309: 222-231, 2003.
-
(2003)
Biochem Biophys Res Commun
, vol.309
, pp. 222-231
-
-
Tanaka, T.1
Hanafusa, N.2
Ingelfinger, J.R.3
Ohse, T.4
Fujita, T.5
Nangaku, M.6
-
28
-
-
9644291798
-
Hypoxia in renal disease with proteinuria and/or glomerular hypertension
-
Tanaka T, Miyata T, Inagi R, Fujita T, and Nangaku M. Hypoxia in renal disease with proteinuria and/or glomerular hypertension. Am J Pathol 165: 1979-1992, 2004.
-
(2004)
Am J Pathol
, vol.165
, pp. 1979-1992
-
-
Tanaka, T.1
Miyata, T.2
Inagi, R.3
Fujita, T.4
Nangaku, M.5
-
29
-
-
0024264644
-
Substrate specificity to maintain cellular ATP along the mouse nephron
-
Uchida S and Endou H. Substrate specificity to maintain cellular ATP along the mouse nephron. Am J Physiol Renal Fluid Electrolyte Physiol 255: F977-F983, 1988.
-
(1988)
Am J Physiol Renal Fluid Electrolyte Physiol
, vol.255
-
-
Uchida, S.1
Endou, H.2
-
30
-
-
1042292029
-
Erythropoietin protects against ischaemic acute renal injury
-
Vesey DA, Cheung C, Pat B, Endre Z, Gobe G, and Johnson DW. Erythropoietin protects against ischaemic acute renal injury. Nephrol Dial Transplant 19: 348-355, 2004.
-
(2004)
Nephrol Dial Transplant
, vol.19
, pp. 348-355
-
-
Vesey, D.A.1
Cheung, C.2
Pat, B.3
Endre, Z.4
Gobe, G.5
Johnson, D.W.6
-
31
-
-
0038380470
-
Activation of the hypoxia-inducible factor-pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors
-
Warnecke C, Griethe W, Weidemann A, Jurgensen JS, Willam C, Bachmann S, Ivashchenko Y, Wagner I, Frei U, Wiesener M, and Eckardt KU. Activation of the hypoxia-inducible factor-pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors. FASEB J 17: 1186-1188, 2003.
-
(2003)
FASEB J
, vol.17
, pp. 1186-1188
-
-
Warnecke, C.1
Griethe, W.2
Weidemann, A.3
Jurgensen, J.S.4
Willam, C.5
Bachmann, S.6
Ivashchenko, Y.7
Wagner, I.8
Frei, U.9
Wiesener, M.10
Eckardt, K.U.11
-
32
-
-
0022134205
-
Reduced renal blood flow in early cisplatin-induced acute renal failure in the rat
-
Winston JA and Safirstein R. Reduced renal blood flow in early cisplatin-induced acute renal failure in the rat. Am J Physiol Renal Fluid Electrolyte Physiol 249: F490-F496, 1985.
-
(1985)
Am J Physiol Renal Fluid Electrolyte Physiol
, vol.249
-
-
Winston, J.A.1
Safirstein, R.2
-
33
-
-
3442881606
-
The potential role of hypoxia inducible factor 1α in tumor progression after hypoxia and chemotherapy in hepatocellular carcinoma
-
Yang ZF, Poon RT, To J, Ho DW, and Fan ST. The potential role of hypoxia inducible factor 1α in tumor progression after hypoxia and chemotherapy in hepatocellular carcinoma. Cancer Res 64: 5496-5503, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 5496-5503
-
-
Yang, Z.F.1
Poon, R.T.2
To, J.3
Ho, D.W.4
Fan, S.T.5
|