Kidney hypoxia, attributable to increased oxygen consumption, induces nephropathy independently of hyperglycemia and oxidative stress

Hypertension

Volumn 62, Issue 5, 2013, Pages 914-919

  Friederich Persson, Malou ^a   Thörn, Erik ^b   Hansell, Peter ^a   Nangaku, Masaomi ^b   Levin, Max ^c   Palm, Fredrik ^a,d  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c UNIVERSITY OF TOKYO   (Japan)

^d LINKÖPING UNIVERSITY   (Sweden)

Author keywords

cell hypoxia; chronic kidney disease; dinitrophenols; kidney; nephropathy, chronic tubulointerstitial; oxygen consumption; uncoupling agents

Indexed keywords

2,4 DINITROPHENOL; GLUCOSE; GLYCOGEN; VIMENTIN; UNCOUPLING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DIABETIC NEPHROPATHY; GLOMERULUS FILTRATION RATE; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; HYPERGLYCEMIA; INFLAMMATORY CELL; KIDNEY BLOOD FLOW; KIDNEY CORTEX; KIDNEY ISCHEMIA; KIDNEY MEDULLA; MALE; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; OXYGEN TENSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN URINE LEVEL; RAT; URINARY EXCRETION; ANIMAL; ANOXIA; DRUG EFFECTS; KIDNEY; KIDNEY CIRCULATION; KIDNEY DISEASE; METABOLISM; MITOCHONDRION; PATHOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ANOXIA; DINITROPHENOLS; GLUCOSE; GLYCOGEN; HYPERGLYCEMIA; KIDNEY; KIDNEY DISEASES; MALE; MITOCHONDRIA; OXIDATIVE STRESS; OXYGEN CONSUMPTION; RATS; RATS, SPRAGUE-DAWLEY; RENAL CIRCULATION; UNCOUPLING AGENTS; VIMENTIN;

EID: 84886424419     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.113.01425     Document Type: Article

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