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Volumn 19, Issue 1, 2008, Pages 39-46

Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYLOXALYLGLYCINE; GLYCINE; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR HYDROXYLASE INHIBITOR; MIMOSINE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; UNCLASSIFIED DRUG;

EID: 38149075003     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2006090998     Document Type: Article
Times cited : (242)

References (48)
  • 1
    • 27844612117 scopus 로고    scopus 로고
    • Hypoxia-inducible factor as a physiological regulator
    • Maxwell PH: Hypoxia-inducible factor as a physiological regulator. Exp Physiol 90: 791-797, 2005
    • (2005) Exp Physiol , vol.90 , pp. 791-797
    • Maxwell, P.H.1
  • 2
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
    • Wang GL, Jiang BH, Rue EA, Semenza, GL: Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci U S A 92: 5510-5514, 1995
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 5510-5514
    • Wang, G.L.1    Jiang, B.H.2    Rue, E.A.3    Semenza, G.L.4
  • 3
    • 0033803047 scopus 로고    scopus 로고
    • Surviving ischemia: Adaptive responses mediated by hypoxia-inducible factor 1
    • Semenza GL: Surviving ischemia: adaptive responses mediated by hypoxia-inducible factor 1. J Clin Invest 106: 809-812, 2000
    • (2000) J Clin Invest , vol.106 , pp. 809-812
    • Semenza, G.L.1
  • 4
    • 0026468180 scopus 로고
    • A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
    • Semenza GL, Wang GL: A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 12: 5447-5454, 1992
    • (1992) Mol Cell Biol , vol.12 , pp. 5447-5454
    • Semenza, G.L.1    Wang, G.L.2
  • 5
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza, GL: Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3: 721-732, 2003
    • (2003) Nat Rev Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 6
    • 0028359320 scopus 로고
    • Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: Similarities with the erythropoietin 3′ enhancer
    • Firth JD, Ebert BL, Pugh CW, Ratcliffe PJ: Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3′ enhancer. Proc Natl Acad Sci U S A 91: 6496-6500, 1994
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 6496-6500
    • Firth, J.D.1    Ebert, B.L.2    Pugh, C.W.3    Ratcliffe, P.J.4
  • 7
    • 0031041377 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia
    • Lee PJ, Jiang BH, Chin BY, Iyer NV, Alam J, Semenza GL, Choi AM: Hypoxia-inducible factor-1 mediates transcriptional activation of the heme oxygenase-1 gene in response to hypoxia. J Biol Chem 272: 5375-5381, 1997
    • (1997) J Biol Chem , vol.272 , pp. 5375-5381
    • Lee, P.J.1    Jiang, B.H.2    Chin, B.Y.3    Iyer, N.V.4    Alam, J.5    Semenza, G.L.6    Choi, A.M.7
  • 8
    • 0029039195 scopus 로고
    • Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia
    • Levy AP, Levy NS, Wegner S, Goldberg MA: Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia. J Biol Chem 270: 13333-13340, 1995
    • (1995) J Biol Chem , vol.270 , pp. 13333-13340
    • Levy, A.P.1    Levy, N.S.2    Wegner, S.3    Goldberg, M.A.4
  • 9
    • 0028786601 scopus 로고
    • A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter
    • Melillo G, Musso T, Sica A, Taylor LS, Cox GW, Varesio L: A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. J Exp Med 182: 1683-1693, 1995
    • (1995) J Exp Med , vol.182 , pp. 1683-1693
    • Melillo, G.1    Musso, T.2    Sica, A.3    Taylor, L.S.4    Cox, G.W.5    Varesio, L.6
  • 11
    • 33745763116 scopus 로고    scopus 로고
    • Cerebral preconditioning and ischaemic tolerance
    • Gidday JM: Cerebral preconditioning and ischaemic tolerance. Nat Rev Neurosci 7: 437-448, 2006
    • (2006) Nat Rev Neurosci , vol.7 , pp. 437-448
    • Gidday, J.M.1
  • 12
    • 27844440474 scopus 로고    scopus 로고
    • Realizing the clinical potential of ischemic preconditioning and postconditioning
    • Yellon DM, Hausenloy DJ: Realizing the clinical potential of ischemic preconditioning and postconditioning. Nat Clin Pract Cardiovasc Med 2: 568-575, 2005
    • (2005) Nat Clin Pract Cardiovasc Med , vol.2 , pp. 568-575
    • Yellon, D.M.1    Hausenloy, D.J.2
  • 13
    • 0030937718 scopus 로고    scopus 로고
    • Activation of hypoxia-inducible factor-1; definition of regulatory domains within the alpha subunit
    • Pugh CW, O'Rourke JF, Nagao M, Gleadle JM, Ratcliffe PJ: Activation of hypoxia-inducible factor-1; definition of regulatory domains within the alpha subunit. J Biol Chem 272: 11205-11214, 1997
    • (1997) J Biol Chem , vol.272 , pp. 11205-11214
    • Pugh, C.W.1    O'Rourke, J.F.2    Nagao, M.3    Gleadle, J.M.4    Ratcliffe, P.J.5
  • 14
    • 85190667923 scopus 로고    scopus 로고
    • Epstein AC, Gleadle JM, McNeill LA, Hewitson KS, O'Rourke J, Mole DR, Mukherji M, Metzen E, Wilson MI, Dhanda A, Tian YM, Masson N, Hamilton DL, Jaakkola P, Barstead R, Hodgkin J, Maxwell PH, Pugh CW, Schofield CJ, Ratcliffe PJ: C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 107: 43-54, 2001
    • Epstein AC, Gleadle JM, McNeill LA, Hewitson KS, O'Rourke J, Mole DR, Mukherji M, Metzen E, Wilson MI, Dhanda A, Tian YM, Masson N, Hamilton DL, Jaakkola P, Barstead R, Hodgkin J, Maxwell PH, Pugh CW, Schofield CJ, Ratcliffe PJ: C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 107: 43-54, 2001
  • 18
    • 0037097861 scopus 로고    scopus 로고
    • FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
    • Lando D, Peet DJ, Gorman JJ, Whelan DA, Whitelaw ML, Bruick RK. FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes Dev 16: 1466-1471, 2002
    • (2002) Genes Dev , vol.16 , pp. 1466-1471
    • Lando, D.1    Peet, D.J.2    Gorman, J.J.3    Whelan, D.A.4    Whitelaw, M.L.5    Bruick, R.K.6
  • 19
    • 0032760945 scopus 로고    scopus 로고
    • Structural and mechanistic studies on 2-oxo-glutarate-dependent oxygenases and related enzymes
    • Schofield CJ, Zhang Z: Structural and mechanistic studies on 2-oxo-glutarate-dependent oxygenases and related enzymes. Curr Opin Struct Biol 9: 722-731, 1999
    • (1999) Curr Opin Struct Biol , vol.9 , pp. 722-731
    • Schofield, C.J.1    Zhang, Z.2
  • 22
    • 0038163900 scopus 로고    scopus 로고
    • Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury
    • Cai Z, Manalo DJ, Wei G, Rodriguez ER, Fox-Talbot K, Lu H, Zweier JL, Semenza, GL: Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury. Circulation 108: 79-85, 2003
    • (2003) Circulation , vol.108 , pp. 79-85
    • Cai, Z.1    Manalo, D.J.2    Wei, G.3    Rodriguez, E.R.4    Fox-Talbot, K.5    Lu, H.6    Zweier, J.L.7    Semenza, G.L.8
  • 26
    • 9344262366 scopus 로고    scopus 로고
    • Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1 alpha and AP-1 and iNOS signaling
    • Xi L, Taher M, Yin C, Salloum F, Kukreja RC: Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1 alpha and AP-1 and iNOS signaling. Am J Physiol Heart Circ Physiol 287: H2369-H2375, 2004
    • (2004) Am J Physiol Heart Circ Physiol , vol.287
    • Xi, L.1    Taher, M.2    Yin, C.3    Salloum, F.4    Kukreja, R.C.5
  • 29
    • 0032213236 scopus 로고    scopus 로고
    • The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development
    • Tian H, Hammer RE, Matsumoto AM, Russell DW, McKnight SL: The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development. Genes Dev 12: 3320-3324, 1998
    • (1998) Genes Dev , vol.12 , pp. 3320-3324
    • Tian, H.1    Hammer, R.E.2    Matsumoto, A.M.3    Russell, D.W.4    McKnight, S.L.5
  • 30
    • 0034682513 scopus 로고    scopus 로고
    • The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling
    • Peng J, Zhang L, Drysdale L, Fong GH: The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling. Proc Natl Acad Sci U S A 97: 8386-8391, 2000
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 8386-8391
    • Peng, J.1    Zhang, L.2    Drysdale, L.3    Fong, G.H.4
  • 34
    • 6444242574 scopus 로고    scopus 로고
    • Inhibition of endogenous HIF inactivation induces angiogenesis in ischaemic skeletal muscles of mice
    • Milkiewicz M, Pugh CW, Egginton S: Inhibition of endogenous HIF inactivation induces angiogenesis in ischaemic skeletal muscles of mice. J Physiol 560: 21-26, 2004
    • (2004) J Physiol , vol.560 , pp. 21-26
    • Milkiewicz, M.1    Pugh, C.W.2    Egginton, S.3
  • 35
    • 0032784549 scopus 로고    scopus 로고
    • Protective mechanism of preconditioning hypoxia attenuates apoptosis formation during renal ischemia/reperfusion phase
    • Chien CT, Chen CF, Hsu SM, Lee PH, Lai MK: Protective mechanism of preconditioning hypoxia attenuates apoptosis formation during renal ischemia/reperfusion phase. Transplant Proc 31: 2012-2013, 1999
    • (1999) Transplant Proc , vol.31 , pp. 2012-2013
    • Chien, C.T.1    Chen, C.F.2    Hsu, S.M.3    Lee, P.H.4    Lai, M.K.5
  • 36
    • 0036528246 scopus 로고    scopus 로고
    • Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein
    • Kondo K, Klco J, Nakamura E, Lechpammer M, Kaelin WG Jr: Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein. Cancer Cell 1: 237-246, 2002
    • (2002) Cancer Cell , vol.1 , pp. 237-246
    • Kondo, K.1    Klco, J.2    Nakamura, E.3    Lechpammer, M.4    Kaelin Jr, W.G.5
  • 41
    • 0028142856 scopus 로고
    • Loop diuretics reduce hypoxic damage to proximal tubules of the isolated perfused rat kidney
    • Heyman SN, Rosen S, Epstein FH, Spokes K, Brezis ML: Loop diuretics reduce hypoxic damage to proximal tubules of the isolated perfused rat kidney. Kidney Int 45: 981-985, 1994
    • (1994) Kidney Int , vol.45 , pp. 981-985
    • Heyman, S.N.1    Rosen, S.2    Epstein, F.H.3    Spokes, K.4    Brezis, M.L.5
  • 42
    • 0041842613 scopus 로고    scopus 로고
    • Recent advances in the pathophysiology of ischemic acute renal failure
    • Bonventre JV, Weinberg JM: Recent advances in the pathophysiology of ischemic acute renal failure. J Am Soc Nephrol 14: 2199-2210, 2003
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2199-2210
    • Bonventre, J.V.1    Weinberg, J.M.2
  • 43
    • 33744954065 scopus 로고    scopus 로고
    • Concordant regulation of gene expression by hypoxia and 2-oxo-glutarate- dependent dioxygenase inhibition: The role of HIF-1alpha, HIF-2alpha, and other pathways
    • Elvidge GP, Glenny L, Appelhoff RJ, Ratcliffe PJ, Ragoussis J, Gleadle JM: Concordant regulation of gene expression by hypoxia and 2-oxo-glutarate- dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways. J Biol Chem 281: 15215-15226, 2006
    • (2006) J Biol Chem , vol.281 , pp. 15215-15226
    • Elvidge, G.P.1    Glenny, L.2    Appelhoff, R.J.3    Ratcliffe, P.J.4    Ragoussis, J.5    Gleadle, J.M.6
  • 44
    • 0141890293 scopus 로고    scopus 로고
    • The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia
    • Leonard MO, Cottell DC, Godson C, Brady HR, Taylor CT: The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia. J Biol Chem 278: 40296-40304, 2003
    • (2003) J Biol Chem , vol.278 , pp. 40296-40304
    • Leonard, M.O.1    Cottell, D.C.2    Godson, C.3    Brady, H.R.4    Taylor, C.T.5
  • 48
    • 85047691081 scopus 로고    scopus 로고
    • Heterozygous deficiency of hypoxia-inducible factor-2alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia
    • Brusselmans K, Compernolle V, Tjwa M, Wiesener MS, Maxwell PH, Collen D, Carmeliet P: Heterozygous deficiency of hypoxia-inducible factor-2alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia. J Clin Invest 111: 1519-1527, 2003
    • (2003) J Clin Invest , vol.111 , pp. 1519-1527
    • Brusselmans, K.1    Compernolle, V.2    Tjwa, M.3    Wiesener, M.S.4    Maxwell, P.H.5    Collen, D.6    Carmeliet, P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.