Genome-wide association of hypoxia-inducible factor (HIF)-1α and HIF-2α DNA binding with expression profiling of hypoxia-inducible transcripts

Journal of Biological Chemistry

Volumn 284, Issue 25, 2009, Pages 16767-16775

  Mole, David R ^a   Blancher, Christine ^b   Copley, Richard R ^b   Pollard, Patrick J ^a   Gleadle, Jonathan M ^c   Ragousis, Jiannis ^b   Ratcliffe, Peter J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c FLINDERS MEDICAL CENTRE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE RESPONSE; AFFINITY BINDING; BINDING DATA; BINDING MOTIF; CHROMATIN IMMUNOPRECIPITATION; DNA BINDING; EXPRESSION PROFILING; GENE SUPPRESSION; GENOME-WIDE ASSOCIATION; HYPOXIA-INDUCIBLE FACTORS; ISOFORMS; REGULATED GENES; TRANSCRIPT PROFILING; TRANSCRIPTIONAL RESPONSE;

BINDING ENERGY; GENES; NUCLEIC ACIDS;

BINDING SITES;

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA;

ARTICLE; BINDING AFFINITY; CELL STRAIN MCF 7; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA SEQUENCE; GENE ACTIVATION; GENE ACTIVITY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE LOCUS; GENE REPRESSION; GENETIC ASSOCIATION; GENOME ANALYSIS; HUMAN; HUMAN CELL; NUCLEOTIDE BINDING SITE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION;

BASE SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BINDING SITES; CELL HYPOXIA; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; DNA, NEOPLASM; FEMALE; GENE EXPRESSION PROFILING; GENOME-WIDE ASSOCIATION STUDY; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING;

EID: 67650531089     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M901790200     Document Type: Article

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