-
1
-
-
70350680440
-
Outcomes following diagnosis of acute renal failure in U. S. veterans: Focus on acute tubular necrosis
-
Amdur RL, Chawla LS, Amodeo S, Kimmel PL, Palant CE. Outcomes following diagnosis of acute renal failure in U. S. veterans: focus on acute tubular necrosis. Kidney Int 76: 1089-1097, 2009.
-
(2009)
Kidney Int
, vol.76
, pp. 1089-1097
-
-
Amdur, R.L.1
Chawla, L.S.2
Amodeo, S.3
Kimmel, P.L.4
Palant, C.E.5
-
2
-
-
80053394522
-
Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice
-
Asada N, Takase M, Nakamura J, Oguchi A, Asada M, Suzuki N, Yamamura KI, Nagoshi N, Shibata S, Rao TN, Fehling HJ, Fukatsu A, Minegishi N, Kita T, Kimura T, Okano H, Yamamoto M, Yanagita M. Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice. J Clin Invest 121: 3981-3990, 2011.
-
(2011)
J Clin Invest
, vol.121
, pp. 3981-3990
-
-
Asada, N.1
Takase, M.2
Nakamura, J.3
Oguchi, A.4
Asada, M.5
Suzuki, N.6
Yamamura, K.I.7
Nagoshi, N.8
Shibata, S.9
Rao, T.N.10
Fehling, H.J.11
Fukatsu, A.12
Minegishi, N.13
Kita, T.14
Kimura, T.15
Okano, H.16
Yamamoto, M.17
Yanagita, M.18
-
3
-
-
75849163295
-
Donor treatment with a PHD inhibitor activating HIFs prevents graft injury and prolongs survival in an allogenic kidney transplant model
-
Bernhardt WM, Gottmann U, Doyon F, Buchholz B, Campean V, Schodel J, Reisenbuechler A, Klaus S, Arend M, Flippin L, Willam C, Wiesener MS, Yard B, Warnecke C, Eckardt KU. Donor treatment with a PHD inhibitor activating HIFs prevents graft injury and prolongs survival in an allogenic kidney transplant model. Proc Natl Acad Sci USA 106: 21276-21281, 2009.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 21276-21281
-
-
Bernhardt, W.M.1
Gottmann, U.2
Doyon, F.3
Buchholz, B.4
Campean, V.5
Schodel, J.6
Reisenbuechler, A.7
Klaus, S.8
Arend, M.9
Flippin, L.10
Willam, C.11
Wiesener, M.S.12
Yard, B.13
Warnecke, C.14
Eckardt, K.U.15
-
4
-
-
39749162172
-
Organ protection by hypoxia and hypoxia-inducible factors
-
Bernhardt WM, Warnecke C, Willam C, Tanaka T, Wiesener MS, Eckardt KU. Organ protection by hypoxia and hypoxia-inducible factors. Methods Enzymol 435: 221-245, 2007.
-
(2007)
Methods Enzymol
, vol.435
, pp. 221-245
-
-
Bernhardt, W.M.1
Warnecke, C.2
Willam, C.3
Tanaka, T.4
Wiesener, M.S.5
Eckardt, K.U.6
-
5
-
-
57049181965
-
Erythropoietin expands a stromal cell population that can mediate renoprotection
-
Bi B, Guo J, Marlier A, Lin SR, Cantley LG. Erythropoietin expands a stromal cell population that can mediate renoprotection. Am J Physiol Renal Physiol 295: F1017-F1022, 2008.
-
(2008)
Am J Physiol Renal Physiol
, vol.295
-
-
Bi, B.1
Guo, J.2
Marlier, A.3
Lin, S.R.4
Cantley, L.G.5
-
6
-
-
27944451518
-
Protection of HIF-1-deficient primary renal tubular epithelial cells from hypoxia-induced cell death is glucose dependent
-
Biju MP, Akai Y, Shrimanker N, Haase VH. Protection of HIF-1-deficient primary renal tubular epithelial cells from hypoxia-induced cell death is glucose dependent. Am J Physiol Renal Physiol 289: F1217-F1226, 2005.
-
(2005)
Am J Physiol Renal Physiol
, vol.289
-
-
Biju, M.P.1
Akai, Y.2
Shrimanker, N.3
Haase, V.H.4
-
7
-
-
4043184065
-
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
-
Ceradini DJ, Kulkarni AR, Callaghan MJ, Tepper OM, Bastidas N, Kleinman ME, Capla JM, Galiano RD, Levine JP, Gurtner GC. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat Med 10: 858-864, 2004.
-
(2004)
Nat Med
, vol.10
, pp. 858-864
-
-
Ceradini, D.J.1
Kulkarni, A.R.2
Callaghan, M.J.3
Tepper, O.M.4
Bastidas, N.5
Kleinman, M.E.6
Capla, J.M.7
Galiano, R.D.8
Levine, J.P.9
Gurtner, G.C.10
-
8
-
-
79957821845
-
The severity of acute kidney injury predicts progression to chronic kidney disease
-
Chawla LS, Amdur RL, Amodeo S, Kimmel PL, Palant CE. The severity of acute kidney injury predicts progression to chronic kidney disease. Kidney Int 79: 1361-1369, 2011.
-
(2011)
Kidney Int
, vol.79
, pp. 1361-1369
-
-
Chawla, L.S.1
Amdur, R.L.2
Amodeo, S.3
Kimmel, P.L.4
Palant, C.E.5
-
9
-
-
0037423948
-
HIF-1 a is essential for myeloid cell-mediated inflammation
-
Cramer T, Yamanishi Y, Clausen BE, Förster I, Pawlinski R, Mack-man N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS. HIF-1 a is essential for myeloid cell-mediated inflammation. Cell 112: 645-657, 2003.
-
(2003)
Cell
, vol.112
, pp. 645-657
-
-
Cramer, T.1
Yamanishi, Y.2
Clausen, B.E.3
Förster, I.4
Pawlinski, R.5
Mack-Man, N.6
Haase, V.H.7
Jaenisch, R.8
Corr, M.9
Nizet, V.10
Firestein, G.S.11
Gerber, H.P.12
Ferrara, N.13
Johnson, R.S.14
-
10
-
-
33845321931
-
Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkB activity
-
Cummins EP, Berra E, Comerford KM, Ginouves A, Fitzgerald KT, Seeballuck F, Godson C, Nielsen JE, Moynagh P, Pouyssegur J, Taylor CT. Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkB activity. Proc Natl Acad Sci USA 103: 18154-18159, 2006.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18154-18159
-
-
Cummins, E.P.1
Berra, E.2
Comerford, K.M.3
Ginouves, A.4
Fitzgerald, K.T.5
Seeballuck, F.6
Godson, C.7
Nielsen, J.E.8
Moynagh, P.9
Pouyssegur, J.10
Taylor, C.T.11
-
11
-
-
84934436863
-
Hypoxia-inducible factors: Post-translational crosstalk of signaling pathways
-
Dimova EY, Kietzmann T. Hypoxia-inducible factors: post-translational crosstalk of signaling pathways. Methods Mol Biol 647: 215-236, 2010.
-
(2010)
Methods Mol Biol
, vol.647
, pp. 215-236
-
-
Dimova, E.Y.1
Kietzmann, T.2
-
12
-
-
59349098621
-
Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease
-
Fraisl P, Aragonés J, Carmeliet P. Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease. Nat Rev Drug Discov 8: 139-152, 2009.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 139-152
-
-
Fraisl, P.1
Aragonés, J.2
Carmeliet, P.3
-
13
-
-
33746655373
-
Hypoxia-inducible factors in the kidney
-
Haase VH. Hypoxia-inducible factors in the kidney. Am J Physiol Renal Physiol 291: F271-F281, 2006.
-
(2006)
Am J Physiol Renal Physiol
, vol.291
-
-
Haase, V.H.1
-
14
-
-
36849021771
-
Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition
-
Higgins DF, Kimura K, Bernhardt WM, Shrimanker N, Akai Y, Hohenstein B, Saito Y, Johnson RS, Kretzler M, Cohen CD, Eckardt KU, Iwano M, Haase VH. Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition. J Clin Invest 117: 3810-3820, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 3810-3820
-
-
Higgins, D.F.1
Kimura, K.2
Bernhardt, W.M.3
Shrimanker, N.4
Akai, Y.5
Hohenstein, B.6
Saito, Y.7
Johnson, R.S.8
Kretzler, M.9
Cohen, C.D.10
Eckardt, K.U.11
Iwano, M.12
Haase, V.H.13
-
15
-
-
79953179377
-
Cardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury
-
Hölscher M, Silter M, Krull S, von Ahlen M, Hesse A, Schwartz P, Wielockx B, Breier G, Katschinski DM, Zieseniss A. Cardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury. J Biol Chem 286: 11185-11194, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 11185-11194
-
-
Hölscher, M.1
Silter, M.2
Krull, S.3
von Ahlen, M.4
Hesse, A.5
Schwartz, P.6
Wielockx, B.7
Breier, G.8
Katschinski, D.M.9
Zieseniss, A.10
-
16
-
-
58149485462
-
Acute kidney injury increases risk of ESRD among elderly
-
Ishani A, Xue JL, Himmelfarb J, Eggers PW, Kimmel PL, Molitoris BA, Collins AJ. Acute kidney injury increases risk of ESRD among elderly. J Am Soc Nephrol 20: 223-228, 2009.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 223-228
-
-
Ishani, A.1
Xue, J.L.2
Himmelfarb, J.3
Eggers, P.W.4
Kimmel, P.L.5
Molitoris, B.A.6
Collins, A.J.7
-
17
-
-
43649093915
-
Oxygen sensing by metazoans: The central role of the HIF hydroxylase pathway
-
Kaelin WG, Ratcliffe PJ. Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway. Mol Cell 30: 393-402, 2008.
-
(2008)
Mol Cell
, vol.30
, pp. 393-402
-
-
Kaelin, W.G.1
Ratcliffe, P.J.2
-
18
-
-
77958177671
-
Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia
-
Kapitsinou PP, Liu Q, Unger TL, Rha J, Davidoff O, Keith B, Epstein JA, Moores SL, Erickson-Miller CL, Haase VH. Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia. Blood 116: 3039-3048, 2010.
-
(2010)
Blood
, vol.116
, pp. 3039-3048
-
-
Kapitsinou, P.P.1
Liu, Q.2
Unger, T.L.3
Rha, J.4
Davidoff, O.5
Keith, B.6
Epstein, J.A.7
Moores, S.L.8
Erickson-Miller, C.L.9
Haase, V.H.10
-
19
-
-
57049135813
-
Stable expression of HIF-1a in tubular epithelial cells promotes interstitial fibrosis
-
Kimura K, Iwano M, Higgins DF, Yamaguchi Y, Nakatani K, Harada K, Kubo A, Akai Y, Rankin EB, Neilson EG, Haase VH, Saito Y. Stable expression of HIF-1a in tubular epithelial cells promotes interstitial fibrosis. Am J Physiol Renal Physiol 295: F1023-F1029, 2008.
-
(2008)
Am J Physiol Renal Physiol
, vol.295
-
-
Kimura, K.1
Iwano, M.2
Higgins, D.F.3
Yamaguchi, Y.4
Nakatani, K.5
Harada, K.6
Kubo, A.7
Akai, Y.8
Rankin, E.B.9
Neilson, E.G.10
Haase, V.H.11
Saito, Y.12
-
20
-
-
70349673306
-
Dialysis-requiring acute renal failure increases the risk of progressive chronic kidney disease
-
Lo LJ, Go AS, Chertow GM, McCulloch CE, Fan D, Ordoñez JD, Hsu CY. Dialysis-requiring acute renal failure increases the risk of progressive chronic kidney disease. Kidney Int 76: 893-899, 2009.
-
(2009)
Kidney Int
, vol.76
, pp. 893-899
-
-
Lo, L.J.1
Go, A.S.2
Chertow, G.M.3
McCulloch, C.E.4
Fan, D.5
Ordoñez, J.D.6
Hsu, C.Y.7
-
21
-
-
33749512970
-
+ T lymphocytes
-
+ T lymphocytes. J Immunol 177: 4962-4965, 2006.
-
(2006)
J Immunol
, vol.177
, pp. 4962-4965
-
-
Lukashev, D.1
Klebanov, B.2
Kojima, H.3
Grinberg, A.4
Ohta, A.5
Berenfeld, L.6
Wenger, R.H.7
Ohta, A.8
Sitkovsky, M.9
-
22
-
-
77957254118
-
Loss of hypoxia-inducible factor prolyl hydroxylase activity in cardiomyocytes phenocopies ischemic cardiomyopathy
-
Moslehi J, Minamishima YA, Shi J, Neuberg D, Charytan DM, Padera RF, Signoretti S, Liao R, Kaelin WG. Loss of hypoxia-inducible factor prolyl hydroxylase activity in cardiomyocytes phenocopies ischemic cardiomyopathy. Circulation 122: 1004-1016, 2010.
-
(2010)
Circulation
, vol.122
, pp. 1004-1016
-
-
Moslehi, J.1
Minamishima, Y.A.2
Shi, J.3
Neuberg, D.4
Charytan, D.M.5
Padera, R.F.6
Signoretti, S.7
Liao, R.8
Kaelin, W.G.9
-
23
-
-
84855786346
-
Inhibition of prolyl hydroxylases by dimethyloxaloylglycine after stroke reduces ischemic brain injury and requires hypoxia inducible factor-1a
-
Ogle ME, Gu X, Espinera AR, Wei L. Inhibition of prolyl hydroxylases by dimethyloxaloylglycine after stroke reduces ischemic brain injury and requires hypoxia inducible factor-1a. Neurobiol Dis 45: 733-742, 2012.
-
(2012)
Neurobiol Dis
, vol.45
, pp. 733-742
-
-
Ogle, M.E.1
Gu, X.2
Espinera, A.R.3
Wei, L.4
-
24
-
-
60349119184
-
Measurement of glomerular filtration rate in conscious mice
-
Qi Z, Breyer MD. Measurement of glomerular filtration rate in conscious mice. Methods Mol Biol 466: 61-72, 2009.
-
(2009)
Methods Mol Biol
, vol.466
, pp. 61-72
-
-
Qi, Z.1
Breyer, M.D.2
-
25
-
-
33746017957
-
Major effects of delayed graft function and cold ischaemia time on renal allograft survival
-
Quiroga I, McShane P, Koo DDH, Gray D, Friend PJ, Fuggle S, Darby C. Major effects of delayed graft function and cold ischaemia time on renal allograft survival. Nephrol Dial Transplant 21:1689-1696, 2006.
-
(2006)
Nephrol Dial Transplant
, vol.21
, pp. 1689-1696
-
-
Quiroga, I.1
McShane, P.2
Koo, D.D.H.3
Gray, D.4
Friend, P.J.5
Fuggle, S.6
Darby, C.7
-
26
-
-
16244381736
-
Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice
-
Rankin EB, Higgins DF, Walisser JA, Johnson RS, Bradfield CA, Haase VH. Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice. Mol Cell Biol 25: 3163-3172, 2005.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 3163-3172
-
-
Rankin, E.B.1
Higgins, D.F.2
Walisser, J.A.3
Johnson, R.S.4
Bradfield, C.A.5
Haase, V.H.6
-
27
-
-
37349048502
-
Mucosal protection by hypoxia-inducible factor prolyl hydroxylase inhibition
-
Robinson A, Keely S, Karhausen J, Gerich ME, Furuta GT, Colgan SP. Mucosal protection by hypoxia-inducible factor prolyl hydroxylase inhibition. Gastroenterology 134: 145-155, 2008.
-
(2008)
Gastroenterology
, vol.134
, pp. 145-155
-
-
Robinson, A.1
Keely, S.2
Karhausen, J.3
Gerich, M.E.4
Furuta, G.T.5
Colgan, S.P.6
-
30
-
-
78649705245
-
Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function
-
Tambuwala MM, Cummins EP, Lenihan CR, Kiss J, Stauch M, Scholz CC, Fraisl P, Lasitschka F, Mollenhauer M, Saunders SP, Maxwell PH, Carmeliet P, Fallon PG, Schneider M, Taylor CT. Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function. Gastroenterology 139: 2093-2101, 2010.
-
(2010)
Gastroenterology
, vol.139
, pp. 2093-2101
-
-
Tambuwala, M.M.1
Cummins, E.P.2
Lenihan, C.R.3
Kiss, J.4
Stauch, M.5
Scholz, C.C.6
Fraisl, P.7
Lasitschka, F.8
Mollenhauer, M.9
Saunders, S.P.10
Maxwell, P.H.11
Carmeliet, P.12
Fallon, P.G.13
Schneider, M.14
Taylor, C.T.15
-
31
-
-
23844521731
-
Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators. Acute renal failure in critically ill patients: A multinational, multicenter study
-
Uchino S, Kellum JA, Bellomo R, Doig GS, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Ronco C, Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators. Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 294: 813-818, 2005.
-
(2005)
JAMA
, vol.294
, pp. 813-818
-
-
Uchino, S.1
Kellum, J.A.2
Bellomo, R.3
Doig, G.S.4
Morimatsu, H.5
Morgera, S.6
Schetz, M.7
Tan, I.8
Bouman, C.9
Macedo, E.10
Gibney, N.11
Tolwani, A.12
Ronco, C.13
-
32
-
-
79952215345
-
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice
-
Walmsley SR, Chilvers ER, Thompson AA, Vaughan K, Marriott HM, Parker LC, Shaw G, Parmar S, Schneider M, Sabroe I, Dockrell DH, Milo M, Taylor CT, Johnson RS, Pugh CW, Ratcliffe PJ, Maxwell PH, Carmeliet P, Whyte MKB. Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice. J Clin Invest 121: 1053-1063, 2011.
-
(2011)
J Clin Invest
, vol.121
, pp. 1053-1063
-
-
Walmsley, S.R.1
Chilvers, E.R.2
Thompson, A.A.3
Vaughan, K.4
Marriott, H.M.5
Parker, L.C.6
Shaw, G.7
Parmar, S.8
Schneider, M.9
Sabroe, I.10
Dockrell, D.H.11
Milo, M.12
Taylor, C.T.13
Johnson, R.S.14
Pugh, C.W.15
Ratcliffe, P.J.16
Maxwell, P.H.17
Carmeliet, P.18
Whyte, M.K.B.19
-
33
-
-
84860505643
-
The protective effect of prolyl-hydroxy-lase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment
-
Wang Z, Schley G, Türkoglu G, Burzlaff N, Amann KU, Willam C, Eckardt KU, Bernhardt WM. The protective effect of prolyl-hydroxy-lase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment. Nephrol Dial Transplant 27: 929-936, 2012.
-
(2012)
Nephrol Dial Transplant
, vol.27
, pp. 929-936
-
-
Wang, Z.1
Schley, G.2
Türkoglu, G.3
Burzlaff, N.4
Amann, K.U.5
Willam, C.6
Eckardt, K.U.7
Bernhardt, W.M.8
-
34
-
-
29044436790
-
Inconsistent effects of acidosis on HIF-alpha protein and its target genes
-
Willam C, Warnecke C, Schefold JC, Kügler J, Koehne P, Frei U, Wiesener M, Eckardt KU. Inconsistent effects of acidosis on HIF-alpha protein and its target genes. Pflügers Arch 451: 534-543, 2006.
-
(2006)
Pflügers Arch
, vol.451
, pp. 534-543
-
-
Willam, C.1
Warnecke, C.2
Schefold, J.C.3
Kügler, J.4
Koehne, P.5
Frei, U.6
Wiesener, M.7
Eckardt, K.U.8
-
35
-
-
77952174830
-
Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury
-
Yang L, Besschetnova TY, Brooks CR, Shah JV, Bonventre JV. Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury. Nature Med 16: 535-543, 2010.
-
(2010)
Nature Med
, vol.16
, pp. 535-543
-
-
Yang, L.1
Besschetnova, T.Y.2
Brooks, C.R.3
Shah, J.V.4
Bonventre, J.V.5
|