PPARα attenuates palmitate-induced endoplasmic reticulum stress in human cardiac cells by enhancing AMPK activity;PPARα atenúa el estrés del retículo endoplasmático inducido por palmitato en células cardíacas humanas por medio de la inducción de la actividad AMPK

Clinica e Investigacion en Arteriosclerosis

Volumn 26, Issue 6, 2014, Pages 255-267

  Palomer, Xavier ^a   Capdevila Busquets, Eva ^a   Garreta, Gerard ^a   Davidson, Mercy M ^b   Vázquez Carrera, Manuel ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

AMP activated protein kinase; Cardiomyocyte; Diabetic cardiomyopathy; Endoplasmic reticulum stress; Heart; Peroxisome proliferator activated receptor alpha

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; CELL MARKER; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INITIATION FACTOR 2ALPHA; PALMITIC ACID; PIRINIXIC ACID; PROTEIN IRE1; PROTEIN IRE1 ALPHA; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; PALMITIC ACID DERIVATIVE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PYRIMIDINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATF3 GENE; BIP GENE; CANCER CELL LINE; CHOP GENE; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION; GRP78 GENE; HEART; HEART MUSCLE CELL; HUMAN; HUMAN CELL; IN VIVO STUDY; LIPID DIET; MALE; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; RNA SPLICING; UPREGULATION; WESTERN BLOTTING; XBP1 GENE; AGONISTS; ANIMAL; C57BL MOUSE; CELL LINE; DRUG EFFECTS; METABOLISM; PATHOLOGY; PHYSIOLOGY;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BLOTTING, WESTERN; CELL LINE; ENDOPLASMIC RETICULUM STRESS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MYOCYTES, CARDIAC; PALMITATES; PPAR ALPHA; PYRIMIDINES; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84912103385     PISSN: 02149168     EISSN: 15781879     Source Type: Journal    
DOI: 10.1016/j.arteri.2014.02.003     Document Type: Article

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