Imatinib mesylate reduces endoplasmic reticulum stress and induces remission of Diabetes in db/db mice

Diabetes

Volumn 58, Issue 2, 2009, Pages 329-336

  Han, Myoung Sook ^a   Chung, Kun Wook ^a   Cheon, Hyae Gyeong ^b   Rhee, Sang Dal ^b   Yoon, Chang Hwan ^c   Lee, Moon Kyu ^a   Kim, Kwang Won ^a   Lee, Myung Shik ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Korea Research Institute of Chemical Technology   (South Korea)

^c Hanyang University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; GLUCOSE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; IMATINIB; INITIATION FACTOR 2ALPHA; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TRIACYLGLYCEROL; CELL CYCLE PROTEIN; INITIATION FACTOR 2; PIPERAZINE DERIVATIVE; PROTEIN KINASE INHIBITOR; PYRIMIDINE DERIVATIVE; TRB3 PROTEIN, MOUSE;

AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CHRONIC LEUKEMIA; CONTROLLED STUDY; DISEASE MODEL; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG EFFECT; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; GLUCOSE TOLERANCE TEST; HUMAN; HUMAN CELL; INSULIN RESISTANCE; INSULIN TOLERANCE TEST; MOUSE; MOUSE STRAIN; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REMISSION; SIGNAL TRANSDUCTION; ADIPOSE TISSUE; ANIMAL; C57BL MOUSE; ENDOPLASMIC RETICULUM; IMMUNOHISTOCHEMISTRY; LIVER; METABOLISM; NICK END LABELING; TUMOR CELL LINE;

ADIPOSE TISSUE; ANIMALS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DIABETES MELLITUS, TYPE 2; ENDOPLASMIC RETICULUM; EUKARYOTIC INITIATION FACTOR-2; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER; MICE; MICE, INBRED C57BL; PIPERAZINES; PROTEIN KINASE INHIBITORS; PYRIMIDINES; REMISSION INDUCTION; TRANSCRIPTION FACTOR CHOP;

EID: 63249105863     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db08-0080     Document Type: Article

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