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Volumn 141, Issue 23, 2014, Pages 4432-4447

The cellular and molecular mechanisms of vertebrate lens development

Author keywords

Cell determination; Crystallins; Differentiation; Lens; Pax6; Pre placodal region

Indexed keywords

CRYSTALLIN; FIBROBLAST GROWTH FACTOR; TRANSCRIPTION FACTOR C MAF; TRANSCRIPTION FACTOR PAX6; EYE PROTEIN; HOMEODOMAIN PROTEIN; PAIRED BOX TRANSCRIPTION FACTOR; REPRESSOR PROTEIN;

EID: 84911469100     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.107953     Document Type: Review
Times cited : (181)

References (248)
  • 1
    • 0032941091 scopus 로고    scopus 로고
    • Differential transcriptional control as the major molecular event in generating Otx1-/- and Otx2-/- divergent phenotypes
    • Acampora, D., Avantaggiato, V., Tuorto, F., Barone, P., Perera, M., Choo, D., Wu, D., Corte, G. and Simeone, A. (1999). Differential transcriptional control as the major molecular event in generating Otx1-/- and Otx2-/- divergent phenotypes. Development 126, 1417-1426.
    • (1999) Development , vol.126 , pp. 1417-1426
    • Acampora, D.1    Avantaggiato, V.2    Tuorto, F.3    Barone, P.4    Perera, M.5    Choo, D.6    Wu, D.7    Corte, G.8    Simeone, A.9
  • 2
    • 0242573122 scopus 로고    scopus 로고
    • Aquaporin water channels: Molecular mechanisms for human diseases
    • Agre, P. and Kozono, D. (2003). Aquaporin water channels: molecular mechanisms for human diseases. FEBS Lett. 555, 72-78.
    • (2003) FEBS Lett. , vol.555 , pp. 72-78
    • Agre, P.1    Kozono, D.2
  • 5
    • 84908685405 scopus 로고    scopus 로고
    • Ectopic activation of Wnt/beta-catenin signaling in lens fiber cells results in cataract formation and aberrant fiber cell differentiation
    • Antosova, B., Smolikova, J., Borkovcova, R., Strnad, H., Lachova, J., Machon, O. and Kozmik, Z. (2013). Ectopic activation of Wnt/beta-catenin signaling in lens fiber cells results in cataract formation and aberrant fiber cell differentiation. PLoS ONE 8, e78279.
    • (2013) PLoS ONE , vol.8
    • Antosova, B.1    Smolikova, J.2    Borkovcova, R.3    Strnad, H.4    Lachova, J.5    Machon, O.6    Kozmik, Z.7
  • 6
    • 0037403778 scopus 로고    scopus 로고
    • Pax6 autoregulation mediated by direct interaction of Pax6 protein with the head surface ectoderm-specific enhancer of the mouse Pax6 gene
    • Aota, S.-I., Nakajima, N., Sakamoto, R., Watanabe, S., Ibaraki, N. and Okazaki, K. (2003). Pax6 autoregulation mediated by direct interaction of Pax6 protein with the head surface ectoderm-specific enhancer of the mouse Pax6 gene. Dev. Biol. 257, 1-13.
    • (2003) Dev. Biol. , vol.257 , pp. 1-13
    • Aota, S.-I.1    Nakajima, N.2    Sakamoto, R.3    Watanabe, S.4    Ibaraki, N.5    Okazaki, K.6
  • 8
    • 0034312313 scopus 로고    scopus 로고
    • Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye
    • Ashery-Padan, R., Marquardt, T., Zhou, X. and Gruss, P. (2000). Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye. Genes Dev. 14, 2701-2711.
    • (2000) Genes Dev. , vol.14 , pp. 2701-2711
    • Ashery-Padan, R.1    Marquardt, T.2    Zhou, X.3    Gruss, P.4
  • 9
    • 84860374004 scopus 로고    scopus 로고
    • Direct visualization of specifically modified extracellular glycans in living animals
    • Attreed, M., Desbois, M., van Kuppevelt, T. H. and Bülow, H. E. (2012). Direct visualization of specifically modified extracellular glycans in living animals. Nat. Methods 9, 477-479.
    • (2012) Nat. Methods , vol.9 , pp. 477-479
    • Attreed, M.1    Desbois, M.2    van Kuppevelt, T.H.3    Bülow, H.E.4
  • 11
    • 33749130424 scopus 로고    scopus 로고
    • Lens specification is the ground state of all sensory placodes, fromwhich FGF promotes olfactory identity
    • Bailey, A. P., Bhattacharyya, S., Bronner-Fraser, M. and Streit, A. (2006). Lens specification is the ground state of all sensory placodes, fromwhich FGF promotes olfactory identity. Dev. Cell 11, 505-517.
    • (2006) Dev. Cell , vol.11 , pp. 505-517
    • Bailey, A.P.1    Bhattacharyya, S.2    Bronner-Fraser, M.3    Streit, A.4
  • 12
    • 0037093507 scopus 로고    scopus 로고
    • Three habits of highly effective signaling pathways: Principles of transcriptional control by developmental cell signaling
    • Barolo, S. and Posakony, J. W. (2002). Three habits of highly effective signaling pathways: principles of transcriptional control by developmental cell signaling. Genes Dev. 16, 1167-1181.
    • (2002) Genes Dev. , vol.16 , pp. 1167-1181
    • Barolo, S.1    Posakony, J.W.2
  • 13
    • 61849099467 scopus 로고    scopus 로고
    • On the mechanism of organelle degradation in the vertebrate lens
    • Bassnett, S. (2009). On the mechanism of organelle degradation in the vertebrate lens. Exp. Eye Res. 88, 133-139.
    • (2009) Exp. Eye Res. , vol.88 , pp. 133-139
    • Bassnett, S.1
  • 14
    • 0031002566 scopus 로고    scopus 로고
    • Chromatin degradation in differentiating fiber cells of the eye lens
    • Bassnett, S. and Mataic, D. (1997). Chromatin degradation in differentiating fiber cells of the eye lens. J. Cell Biol. 137, 37-49.
    • (1997) J. Cell Biol. , vol.137 , pp. 37-49
    • Bassnett, S.1    Mataic, D.2
  • 16
    • 84858060155 scopus 로고    scopus 로고
    • Insulin-like growth factor receptor-1 and nuclear factor kappaB are crucial survival signals that regulate caspase-3-mediated lens epithelial cell differentiation initiation
    • Basu, S., Rajakaruna, S. and Menko, A. S. (2012). Insulin-like growth factor receptor-1 and nuclear factor kappaB are crucial survival signals that regulate caspase-3-mediated lens epithelial cell differentiation initiation. J. Biol. Chem. 287, 8384-8397.
    • (2012) J. Biol. Chem. , vol.287 , pp. 8384-8397
    • Basu, S.1    Rajakaruna, S.2    Menko, A.S.3
  • 17
    • 84894198332 scopus 로고    scopus 로고
    • α6 integrin transactivates insulin-like growth factor receptor-1 (IGF-1R) to regulate caspase-3-mediated lens epithelial cell differentiation initiation
    • Basu, S., Rajakaruna, S., De Arcangelis, A., Zhang, L., Georges-Labouesse, E. and Menko, A. S. (2014a). α6 integrin transactivates insulin-like growth factor receptor-1 (IGF-1R) to regulate caspase-3-mediated lens epithelial cell differentiation initiation. J. Biol. Chem. 289, 3842-3855.
    • (2014) J. Biol. Chem. , vol.289 , pp. 3842-3855
    • Basu, S.1    Rajakaruna, S.2    De Arcangelis, A.3    Zhang, L.4    Georges-Labouesse, E.5    Menko, A.S.6
  • 18
    • 84903841596 scopus 로고    scopus 로고
    • Suppression of MAPK/JNK-MTORC1 signaling leads to premature loss of organelles and nuclei by autophagy during terminal differentiation of lens fiber cells
    • Basu, S., Rajakaruna, S., Reyes, B., Van Bockstaele, E. and Menko, A. S. (2014b). Suppression of MAPK/JNK-MTORC1 signaling leads to premature loss of organelles and nuclei by autophagy during terminal differentiation of lens fiber cells. Autophagy 10, 1193-1211.
    • (2014) Autophagy , vol.10 , pp. 1193-1211
    • Basu, S.1    Rajakaruna, S.2    Reyes, B.3    Van Bockstaele, E.4    Menko, A.S.5
  • 19
    • 0036805779 scopus 로고    scopus 로고
    • Pax6 heterozygous eyes show defects in chamber angle differentiation that are associated with a wide spectrum of other anterior eye segment abnormalities
    • Baulmann, D. C., Ohlmann, A., Flügel-Koch, C., Goswami, S., Cvekl, A. and Tamm, E. R. (2002). Pax6 heterozygous eyes show defects in chamber angle differentiation that are associated with a wide spectrum of other anterior eye segment abnormalities. Mech. Dev. 118, 3-17.
    • (2002) Mech. Dev. , vol.118 , pp. 3-17
    • Baulmann, D.C.1    Ohlmann, A.2    Flügel-Koch, C.3    Goswami, S.4    Cvekl, A.5    Tamm, E.R.6
  • 20
    • 3042598155 scopus 로고    scopus 로고
    • Segregation of lens and olfactory precursors from a common territory: Cell sorting and reciprocity of Dlx5 and Pax6 expression
    • Bhattacharyya, S., Bailey, A. P., Bronner-Fraser, M. and Streit, A. (2004). Segregation of lens and olfactory precursors from a common territory: cell sorting and reciprocity of Dlx5 and Pax6 expression. Dev. Biol. 271, 403-414.
    • (2004) Dev. Biol. , vol.271 , pp. 403-414
    • Bhattacharyya, S.1    Bailey, A.P.2    Bronner-Fraser, M.3    Streit, A.4
  • 22
    • 33846186034 scopus 로고    scopus 로고
    • Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage
    • Blixt, A., Landgren, H., Johansson, B. R. and Carlsson, P. (2007). Foxe3 is required for morphogenesis and differentiation of the anterior segment of the eye and is sensitive to Pax6 gene dosage. Dev. Biol. 302, 218-229.
    • (2007) Dev. Biol. , vol.302 , pp. 218-229
    • Blixt, A.1    Landgren, H.2    Johansson, B.R.3    Carlsson, P.4
  • 23
    • 56449131346 scopus 로고    scopus 로고
    • Essential role of BMPs in FGF-induced secondary lens fiber differentiation
    • Boswell, B. A., Overbeek, P. A. and Musil, L. S. (2008). Essential role of BMPs in FGF-induced secondary lens fiber differentiation. Dev. Biol. 324, 202-212.
    • (2008) Dev. Biol. , vol.324 , pp. 202-212
    • Boswell, B.A.1    Overbeek, P.A.2    Musil, L.S.3
  • 24
    • 0031017669 scopus 로고    scopus 로고
    • Targeted disruption of the mouse αA-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein αB-crystallin
    • Brady, J. P., Garland, D., Duglas-Tabor, Y., Robison, W. G., Jr, Groome, A. and Wawrousek, E. F. (1997). Targeted disruption of the mouse αA-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein αB-crystallin. Proc. Natl. Acad. Sci. USA 94, 884-889.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 884-889
    • Brady, J.P.1    Garland, D.2    Duglas-Tabor, Y.3    Robison, W.G.4    Groome, A.5    Wawrousek, E.F.6
  • 27
    • 33751331884 scopus 로고    scopus 로고
    • Deletion of DDB1 in mouse brain and lens leads to p53-dependent elimination of proliferating cells
    • Cang, Y., Zhang, J., Nicholas, S. A., Bastien, J., Li, B., Zhou, P. and Goff, S. P. (2006). Deletion of DDB1 in mouse brain and lens leads to p53-dependent elimination of proliferating cells. Cell 127, 929-940.
    • (2006) Cell , vol.127 , pp. 929-940
    • Cang, Y.1    Zhang, J.2    Nicholas, S.A.3    Bastien, J.4    Li, B.5    Zhou, P.6    Goff, S.P.7
  • 28
    • 79952586755 scopus 로고    scopus 로고
    • Lens induction requires attenuation of ERK signaling by Nf1
    • Carbe, C. and Zhang, X. (2011). Lens induction requires attenuation of ERK signaling by Nf1. Hum. Mol. Genet. 20, 1315-1323.
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 1315-1323
    • Carbe, C.1    Zhang, X.2
  • 30
    • 84906246203 scopus 로고    scopus 로고
    • Nuclear removal during terminal lens fiber cell differentiation requires CDK1 activity: Appropriating mitosis-related nuclear disassembly
    • Chaffee, B. R., Shang, F., Chang, M.-L., Clement, T. M., Eddy, E. M., Wagner, B. D., Nakahara, M., Nagata, S., Robinson, M. L. and Taylor, A. (2014). Nuclear removal during terminal lens fiber cell differentiation requires CDK1 activity: appropriating mitosis-related nuclear disassembly. Development 141, 3388-3398.
    • (2014) Development , vol.141 , pp. 3388-3398
    • Chaffee, B.R.1    Shang, F.2    Chang, M.-L.3    Clement, T.M.4    Eddy, E.M.5    Wagner, B.D.6    Nakahara, M.7    Nagata, S.8    Robinson, M.L.9    Taylor, A.10
  • 31
    • 70350179623 scopus 로고    scopus 로고
    • Cdc42- and IRSp53-dependent contractile filopodia tether presumptive lens and retina to coordinate epithelial invagination
    • Chauhan, B. K., Disanza, A., Choi, S.-Y., Faber, S. C., Lou, M., Beggs, H. E., Scita, G., Zheng, Y. and Lang, R. A. (2009). Cdc42- and IRSp53-dependent contractile filopodia tether presumptive lens and retina to coordinate epithelial invagination. Development 136, 3657-3667.
    • (2009) Development , vol.136 , pp. 3657-3667
    • Chauhan, B.K.1    Disanza, A.2    Choi, S.-Y.3    Faber, S.C.4    Lou, M.5    Beggs, H.E.6    Scita, G.7    Zheng, Y.8    Lang, R.A.9
  • 32
    • 81055130119 scopus 로고    scopus 로고
    • Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia
    • Chauhan, B. K., Lou, M., Zheng, Y. and Lang, R. A. (2011). Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia. Proc. Natl. Acad. Sci. USA 108, 18289-18294.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 18289-18294
    • Chauhan, B.K.1    Lou, M.2    Zheng, Y.3    Lang, R.A.4
  • 33
    • 84906279663 scopus 로고    scopus 로고
    • Differentiation state-specific mitochondrial dynamic regulatory networks are revealed by global transcriptional analysis of the developing chicken lens
    • Chauss, D., Basu, S., Rajakaruna, S., Ma, Z., Gau, V., Anastas, S., Brennan, L. A., Hejtmancik, J. F., Menko, A. S. and Kantorow, M. (2014). Differentiation state-specific mitochondrial dynamic regulatory networks are revealed by global transcriptional analysis of the developing chicken lens. G3 (Bethesda) 4, 1515-1527.
    • (2014) G3 (Bethesda) , vol.4 , pp. 1515-1527
    • Chauss, D.1    Basu, S.2    Rajakaruna, S.3    Ma, Z.4    Gau, V.5    Anastas, S.6    Brennan, L.A.7    Hejtmancik, J.F.8    Menko, A.S.9    Kantorow, M.10
  • 34
    • 0033652278 scopus 로고    scopus 로고
    • Induction of cell cycle entry and cell death in postmitotic lens fiber cells by overexpression of E2F1 or E2F2
    • Chen, Q., Hung, F. C., Fromm, L. and Overbeek, P. A. (2000). Induction of cell cycle entry and cell death in postmitotic lens fiber cells by overexpression of E2F1 or E2F2. Invest. Ophthalmol. Vis. Sci. 41, 4223-3421.
    • (2000) Invest. Ophthalmol. Vis. Sci. , vol.41
    • Chen, Q.1    Hung, F.C.2    Fromm, L.3    Overbeek, P.A.4
  • 36
    • 55749100664 scopus 로고    scopus 로고
    • Wnt signaling is required for organization of the lens fiber cell cytoskeleton and development of lens three-dimensional architecture
    • Chen, Y., Stump, R. J.W., Lovicu, F. J., Shimono, A. and McAvoy, J.W. (2008b). Wnt signaling is required for organization of the lens fiber cell cytoskeleton and development of lens three-dimensional architecture. Dev. Biol. 324, 161-176.
    • (2008) Dev. Biol. , vol.324 , pp. 161-176
    • Chen, Y.1    Stump, R.J.W.2    Lovicu, F.J.3    Shimono, A.4    McAvoy, J.W.5
  • 38
    • 84884970717 scopus 로고    scopus 로고
    • EphA2 and Src regulate equatorial cell morphogenesis during lens development
    • Cheng, C., Ansari, M. M., Cooper, J. A. and Gong, X. (2013). EphA2 and Src regulate equatorial cell morphogenesis during lens development. Development 140, 4237-4245.
    • (2013) Development , vol.140 , pp. 4237-4245
    • Cheng, C.1    Ansari, M.M.2    Cooper, J.A.3    Gong, X.4
  • 39
    • 84879000901 scopus 로고    scopus 로고
    • Translation initiation factor eIF3h targets specific transcripts to polysomes during embryogenesis
    • Choudhuri, A., Maitra, U. and Evans, T. (2013). Translation initiation factor eIF3h targets specific transcripts to polysomes during embryogenesis. Proc. Natl. Acad. Sci. USA 110, 9818-9823.
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 9818-9823
    • Choudhuri, A.1    Maitra, U.2    Evans, T.3
  • 41
    • 84887057344 scopus 로고    scopus 로고
    • Non-coding RNAs in the development of sensory organs and related diseases
    • Conte, I., Banfi, S. and Bovolenta, P. (2013). Non-coding RNAs in the development of sensory organs and related diseases. Cell. Mol. Life Sci. 70, 4141-4155.
    • (2013) Cell. Mol. Life Sci. , vol.70 , pp. 4141-4155
    • Conte, I.1    Banfi, S.2    Bovolenta, P.3
  • 42
    • 55949135635 scopus 로고    scopus 로고
    • Loss of ephrin-A5 function disrupts lens fiber cell packing and leads to cataract
    • Cooper,M. A., Son, A. I., Komlos, D., Sun, Y., Kleiman, N. J. and Zhou, R. (2008). Loss of ephrin-A5 function disrupts lens fiber cell packing and leads to cataract. Proc. Natl. Acad. Sci. USA 105, 16620-16625.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 16620-16625
    • Cooper, M.A.1    Son, A.I.2    Komlos, D.3    Sun, Y.4    Kleiman, N.J.5    Zhou, R.6
  • 45
    • 0036479110 scopus 로고    scopus 로고
    • Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors
    • Crawford, S. E., Qi, C., Misra, P., Stellmach, V., Rao, M. S., Engel, J. D., Zhu, Y. and Reddy, J. K. (2002). Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors. J. Biol. Chem. 277, 3585-3592.
    • (2002) J. Biol. Chem. , vol.277 , pp. 3585-3592
    • Crawford, S.E.1    Qi, C.2    Misra, P.3    Stellmach, V.4    Rao, M.S.5    Engel, J.D.6    Zhu, Y.7    Reddy, J.K.8
  • 46
    • 35348996450 scopus 로고    scopus 로고
    • Genetic and epigenetic mechanisms of gene regulation during lens development
    • Cvekl, A. and Duncan, M. K. (2007). Genetic and epigenetic mechanisms of gene regulation during lens development. Prog. Retin. Eye Res. 26, 555-597.
    • (2007) Prog. Retin. Eye Res. , vol.26 , pp. 555-597
    • Cvekl, A.1    Duncan, M.K.2
  • 47
    • 77953808789 scopus 로고    scopus 로고
    • Epigenetic regulatory mechanisms in vertebrate eye development and disease
    • Cvekl, A. and Mitton, K. P. (2010). Epigenetic regulatory mechanisms in vertebrate eye development and disease. Heredity 105, 135-151.
    • (2010) Heredity , vol.105 , pp. 135-151
    • Cvekl, A.1    Mitton, K.P.2
  • 48
    • 1842714360 scopus 로고    scopus 로고
    • Anterior eye development and ocular mesenchyme: New insights from mouse models and human diseases
    • Cvekl, A. and Tamm, E. R. (2004). Anterior eye development and ocular mesenchyme: new insights from mouse models and human diseases. Bioessays 26, 374-386.
    • (2004) Bioessays , vol.26 , pp. 374-386
    • Cvekl, A.1    Tamm, E.R.2
  • 49
    • 67651218981 scopus 로고    scopus 로고
    • Retinoic acid signaling in mammalian eye development
    • Cvekl, A. and Wang, W.-L. (2009). Retinoic acid signaling in mammalian eye development. Exp. Eye Res. 89, 280-291.
    • (2009) Exp. Eye Res. , vol.89 , pp. 280-291
    • Cvekl, A.1    Wang, W.-L.2
  • 50
    • 84874629562 scopus 로고    scopus 로고
    • Wnt-frizzled signaling is part of an FGF-induced cascade that promotes lens fiber differentiation
    • Dawes, L. J., Sugiyama, Y., Tanedo, A. S., Lovicu, F. J. and McAvoy, J. W. (2013). Wnt-frizzled signaling is part of an FGF-induced cascade that promotes lens fiber differentiation. Invest. Ophthalmol. Vis. Sci. 54, 1582-1590.
    • (2013) Invest. Ophthalmol. Vis. Sci. , vol.54 , pp. 1582-1590
    • Dawes, L.J.1    Sugiyama, Y.2    Tanedo, A.S.3    Lovicu, F.J.4    McAvoy, J.W.5
  • 51
    • 84891634650 scopus 로고    scopus 로고
    • Interactions between lens epithelial and fiber cells reveal an intrinsic self-assembly mechanism
    • Dawes, L. J., Sugiyama, Y., Lovicu, F. J., Harris, C. G., Shelley, E. J. and McAvoy, J. W. (2014). Interactions between lens epithelial and fiber cells reveal an intrinsic self-assembly mechanism. Dev. Biol. 385, 291-303.
    • (2014) Dev. Biol. , vol.385 , pp. 291-303
    • Dawes, L.J.1    Sugiyama, Y.2    Lovicu, F.J.3    Harris, C.G.4    Shelley, E.J.5    McAvoy, J.W.6
  • 52
    • 0035195501 scopus 로고    scopus 로고
    • The upstream ectoderm enhancer in Pax6 has an important role in lens induction
    • Dimanlig, P. V., Faber, S. C., Auerbach, W., Makarenkova, H. P. and Lang, R. A. (2001). The upstream ectoderm enhancer in Pax6 has an important role in lens induction. Development 128, 4415-4424.
    • (2001) Development , vol.128 , pp. 4415-4424
    • Dimanlig, P.V.1    Faber, S.C.2    Auerbach, W.3    Makarenkova, H.P.4    Lang, R.A.5
  • 53
    • 84890143546 scopus 로고    scopus 로고
    • Specification of functional cranial placode derivatives from human pluripotent stem cells
    • Dincer, Z., Piao, J., Niu, L., Ganat, Y., Kriks, S., Zimmer, B., Shi, S.-H., Tabar, V. and Studer, L. (2013). Specification of functional cranial placode derivatives from human pluripotent stem cells. Cell Rep. 5, 1387-1402.
    • (2013) Cell Rep. , vol.5 , pp. 1387-1402
    • Dincer, Z.1    Piao, J.2    Niu, L.3    Ganat, Y.4    Kriks, S.5    Zimmer, B.6    Shi, S.-H.7    Tabar, V.8    Studer, L.9
  • 54
    • 11144268967 scopus 로고    scopus 로고
    • Conservation and non-conservation of genetic pathways in eye specification
    • Donner, A. L. and Maas, R. L. (2004). Conservation and non-conservation of genetic pathways in eye specification. Int. J. Dev. Biol. 48, 743-753.
    • (2004) Int. J. Dev. Biol. , vol.48 , pp. 743-753
    • Donner, A.L.1    Maas, R.L.2
  • 55
    • 33847376751 scopus 로고    scopus 로고
    • Sox2 and Pou2f1 interact to control lens and olfactory placode development
    • Donner, A. L., Episkopou, V. and Maas, R. L. (2007). Sox2 and Pou2f1 interact to control lens and olfactory placode development. Dev. Biol. 303, 784-799.
    • (2007) Dev. Biol. , vol.303 , pp. 784-799
    • Donner, A.L.1    Episkopou, V.2    Maas, R.L.3
  • 56
    • 45549103378 scopus 로고    scopus 로고
    • Foxg1 is required for development of the vertebrate olfactory system
    • Duggan, C. D., DeMaria, S., Baudhuin, A., Stafford, D. and Ngai, J. (2008). Foxg1 is required for development of the vertebrate olfactory system. J. Neurosci. 28, 5229-5239.
    • (2008) J. Neurosci. , vol.28 , pp. 5229-5239
    • Duggan, C.D.1    DeMaria, S.2    Baudhuin, A.3    Stafford, D.4    Ngai, J.5
  • 57
    • 0036177940 scopus 로고    scopus 로고
    • Prox1 is differentially localized during lens development
    • Duncan, M. K., Cui, W., Oh, D.-J. and Tomarev, S. I. (2002). Prox1 is differentially localized during lens development. Mech. Dev. 112, 195-198.
    • (2002) Mech. Dev. , vol.112 , pp. 195-198
    • Duncan, M.K.1    Cui, W.2    Oh, D.-J.3    Tomarev, S.I.4
  • 58
    • 0034194543 scopus 로고    scopus 로고
    • Altered retinoid signaling in the heads of small eye mouse embryos
    • Enwright, J. F., III and Grainger, R. M. (2000). Altered retinoid signaling in the heads of small eye mouse embryos. Dev. Biol. 221, 10-22.
    • (2000) Dev. Biol. , vol.221 , pp. 10-22
    • Enwright, J.F.1    Grainger, R.M.2
  • 59
    • 0036677580 scopus 로고    scopus 로고
    • Bmp signaling is required for development of primary lens fiber cells
    • Faber, S. C., Robinson, M. L., Makarenkova, H. P. and Lang, R. A. (2002). Bmp signaling is required for development of primary lens fiber cells. Development 129, 3727-3737.
    • (2002) Development , vol.129 , pp. 3727-3737
    • Faber, S.C.1    Robinson, M.L.2    Makarenkova, H.P.3    Lang, R.A.4
  • 60
    • 3543046713 scopus 로고    scopus 로고
    • Temporal regulation of VEID- 7-amino-4-trifluoromethylcoumarin cleavage activity and caspase-6 correlates with organelle loss during lens development
    • Foley, J. D., Rosenbaum, H. and Griep, A. E. (2004). Temporal regulation of VEID- 7-amino-4-trifluoromethylcoumarin cleavage activity and caspase-6 correlates with organelle loss during lens development. J. Biol. Chem. 279, 32142-32150.
    • (2004) J. Biol. Chem. , vol.279 , pp. 32142-32150
    • Foley, J.D.1    Rosenbaum, H.2    Griep, A.E.3
  • 63
    • 57649155181 scopus 로고    scopus 로고
    • Analysis of HSF4 binding regions reveals its necessity for gene regulation during development and heat shock response in mouse lenses
    • Fujimoto, M., Oshima, K., Shinkawa, T., Wang, B. B., Inouye, S., Hayashida, N., Takii, R. and Nakai, A. (2008). Analysis of HSF4 binding regions reveals its necessity for gene regulation during development and heat shock response in mouse lenses. J. Biol. Chem. 283, 29961-29970.
    • (2008) J. Biol. Chem. , vol.283 , pp. 29961-29970
    • Fujimoto, M.1    Oshima, K.2    Shinkawa, T.3    Wang, B.B.4    Inouye, S.5    Hayashida, N.6    Takii, R.7    Nakai, A.8
  • 64
    • 0032430772 scopus 로고    scopus 로고
    • BMP4 is essential for lens induction in the mouse embryo
    • Furuta, Y. and Hogan, B. L. M. (1998). BMP4 is essential for lens induction in the mouse embryo. Genes Dev. 12, 3764-3775.
    • (1998) Genes Dev. , vol.12 , pp. 3764-3775
    • Furuta, Y.1    Hogan, B.L.M.2
  • 66
    • 84875421249 scopus 로고    scopus 로고
    • Exploring mechanisms of FGF signalling through the lens of structural biology
    • Goetz, R. and Mohammadi, M. (2013). Exploring mechanisms of FGF signalling through the lens of structural biology. Nat. Rev. Mol. Cell Biol. 14, 166-180.
    • (2013) Nat. Rev. Mol. Cell Biol. , vol.14 , pp. 166-180
    • Goetz, R.1    Mohammadi, M.2
  • 67
    • 84868697480 scopus 로고    scopus 로고
    • Tmod1 and CP49 synergize to control the fiber cell geometry, transparency, and mechanical stiffness of the mouse lens
    • Gokhin, D. S., Nowak, R. B., Kim, N. E., Arnett, E. E., Chen, A. C., Sah, R. L., Clark, J. I. and Fowler, V. M. (2012). Tmod1 and CP49 synergize to control the fiber cell geometry, transparency, and mechanical stiffness of the mouse lens. PLoS ONE 7, e48734.
    • (2012) PLoS ONE , vol.7
    • Gokhin, D.S.1    Nowak, R.B.2    Kim, N.E.3    Arnett, E.E.4    Chen, A.C.5    Sah, R.L.6    Clark, J.I.7    Fowler, V.M.8
  • 68
    • 3843103698 scopus 로고    scopus 로고
    • Lens major intrinsic protein (MIP)/aquaporin 0 expression in rat lens epithelia explants requires fibroblast growth factor-induced ERK and JNK signaling
    • Golestaneh, N., Fan, J., Fariss, R. N., Lo,W.-K., Zelenka, P. S. and Chepelinsky, A. B. (2004). Lens major intrinsic protein (MIP)/aquaporin 0 expression in rat lens epithelia explants requires fibroblast growth factor-induced ERK and JNK signaling. J. Biol. Chem. 279, 31813-31822.
    • (2004) J. Biol. Chem. , vol.279 , pp. 31813-31822
    • Golestaneh, N.1    Fan, J.2    Fariss, R.N.3    Lo, W.-K.4    Zelenka, P.S.5    Chepelinsky, A.B.6
  • 71
    • 0037172981 scopus 로고    scopus 로고
    • Mutually regulated expression of Pax6 and Six3 and its implications for the Pax6 haploinsufficient lens phenotype
    • Goudreau, G., Petrou, P., Reneker, L. W., Graw, J., Löster, J. and Gruss, P. (2002). Mutually regulated expression of Pax6 and Six3 and its implications for the Pax6 haploinsufficient lens phenotype. Proc. Natl. Acad. Sci. USA 99, 8719-8724.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 8719-8724
    • Goudreau, G.1    Petrou, P.2    Reneker, L.W.3    Graw, J.4    Löster, J.5    Gruss, P.6
  • 72
    • 0026800666 scopus 로고
    • Embryonic lens induction: Shedding light on vertebrate tissue determination
    • Grainger, R. M. (1992). Embryonic lens induction: shedding light on vertebrate tissue determination. Trends Genet. 8, 349-355.
    • (1992) Trends Genet. , vol.8 , pp. 349-355
    • Grainger, R.M.1
  • 73
    • 77951884939 scopus 로고    scopus 로고
    • Mouse models of cataract
    • Graw, J. (2009). Mouse models of cataract. J. Genet. 88, 469-486.
    • (2009) J. Genet. , vol.88 , pp. 469-486
    • Graw, J.1
  • 74
    • 2142810974 scopus 로고    scopus 로고
    • Genetic and allelic heterogeneity of Cryg mutations in eight distinct forms of dominant cataract in the mouse
    • Graw, J., Neuhäuser-Klaus, A., Klopp, N., Selby, P. B., Löster, J. and Favor, J. (2004). Genetic and allelic heterogeneity of Cryg mutations in eight distinct forms of dominant cataract in the mouse. Invest. Ophthalmol. Vis. Sci. 45, 1202-1213.
    • (2004) Invest. Ophthalmol. Vis. Sci. , vol.45 , pp. 1202-1213
    • Graw, J.1    Neuhäuser-Klaus, A.2    Klopp, N.3    Selby, P.B.4    Löster, J.5    Favor, J.6
  • 75
    • 73449087379 scopus 로고    scopus 로고
    • The zebrafish lens proteome during development and aging
    • Greiling, T. M., Houck, S. A. and Clark, J. I. (2009). The zebrafish lens proteome during development and aging. Mol. Vis. 15, 2313-2325.
    • (2009) Mol. Vis. , vol.15 , pp. 2313-2325
    • Greiling, T.M.1    Houck, S.A.2    Clark, J.I.3
  • 76
    • 33846364985 scopus 로고    scopus 로고
    • Cell cycle regulation in the developing lens
    • Griep, A. E. (2006). Cell cycle regulation in the developing lens. Semin. Cell Dev. Biol. 17, 686-697.
    • (2006) Semin. Cell Dev. Biol. , vol.17 , pp. 686-697
    • Griep, A.E.1
  • 77
    • 84865649528 scopus 로고    scopus 로고
    • The peripheral sensory nervous system in the vertebrate head: A gene regulatory perspective
    • Grocott, T., Tambalo, M. and Streit, A. (2012). The peripheral sensory nervous system in the vertebrate head: a gene regulatory perspective. Dev. Biol. 370, 3-23.
    • (2012) Dev. Biol. , vol.370 , pp. 3-23
    • Grocott, T.1    Tambalo, M.2    Streit, A.3
  • 79
    • 84901723986 scopus 로고    scopus 로고
    • Setting appropriate boundaries: Fate, patterning and competence at the neural plate border
    • Groves, A. K. and LaBonne, C. (2014). Setting appropriate boundaries: fate, patterning and competence at the neural plate border. Dev. Biol. 389, 2-12.
    • (2014) Dev. Biol. , vol.389 , pp. 2-12
    • Groves, A.K.1    LaBonne, C.2
  • 80
    • 79953168449 scopus 로고    scopus 로고
    • The common modification in αA-crystallin in the lens, N101D, is associated with increased opacity in a mouse model
    • Gupta, R., Asomugha, C. O. and Srivastava, O. P. (2011). The common modification in αA-crystallin in the lens, N101D, is associated with increased opacity in a mouse model. J. Biol. Chem. 286, 11579-11592.
    • (2011) J. Biol. Chem. , vol.286 , pp. 11579-11592
    • Gupta, R.1    Asomugha, C.O.2    Srivastava, O.P.3
  • 82
    • 33646760234 scopus 로고    scopus 로고
    • Developmental malformations of the eye: The role of PAX6, SOX2 and OTX2
    • Hever, A. M., Williamson, K. A. and Van Heyningen, V. (2006). Developmental malformations of the eye: the role of PAX6, SOX2 and OTX2. Clin. Genet. 69, 459-470.
    • (2006) Clin. Genet. , vol.69 , pp. 459-470
    • Hever, A.M.1    Williamson, K.A.2    Van Heyningen, V.3
  • 84
    • 0023787751 scopus 로고
    • Small eye (Sey): A mouse model for the genetic analysis of craniofacial abnormalities
    • Hogan, B. L., Hirst, E. M., Horsburgh, G. and Hetherington, C. M. (1988). Small eye (Sey): a mouse model for the genetic analysis of craniofacial abnormalities. Development 103 Suppl., 115-119.
    • (1988) Development , vol.103 , pp. 115-119
    • Hogan, B.L.1    Hirst, E.M.2    Horsburgh, G.3    Hetherington, C.M.4
  • 87
    • 34548417177 scopus 로고    scopus 로고
    • PAX6 and SOX2-dependent regulation of the Sox2 enhancer N-3 involved in embryonic visual system development
    • Inoue, M., Kamachi, Y.,Matsunami, H., Imada, K., Uchikawa, M. and Kondoh, H. (2007). PAX6 and SOX2-dependent regulation of the Sox2 enhancer N-3 involved in embryonic visual system development. Genes Cells 12, 1049-1061.
    • (2007) Genes Cells , vol.12 , pp. 1049-1061
    • Inoue, M.1    Kamachi, Y.2    Matsunami, H.3    Imada, K.4    Uchikawa, M.5    Kondoh, H.6
  • 88
    • 84871910395 scopus 로고    scopus 로고
    • A balance of FGF and BMP signals regulates cell cycle exit and Equarin expression in lens cells
    • Jarrin, M., Pandit, T. and Gunhaga, L. (2012). A balance of FGF and BMP signals regulates cell cycle exit and Equarin expression in lens cells. Mol. Biol. Cell 23, 3266-3274.
    • (2012) Mol. Biol. Cell , vol.23 , pp. 3266-3274
    • Jarrin, M.1    Pandit, T.2    Gunhaga, L.3
  • 89
    • 35148838929 scopus 로고    scopus 로고
    • The Notch signaling pathway controls the size of the ocular lens by directly suppressing p57Kip2 expression
    • Jia, J., Lin, M., Zhang, L., York, J. P. and Zhang, P. (2007). The Notch signaling pathway controls the size of the ocular lens by directly suppressing p57Kip2 expression. Mol. Cell. Biol. 27, 7236-7247.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 7236-7247
    • Jia, J.1    Lin, M.2    Zhang, L.3    York, J.P.4    Zhang, P.5
  • 90
    • 79956372548 scopus 로고    scopus 로고
    • The fate of dividing cells during lens morphogenesis, differentiation and growth
    • Kallifatidis, G., Boros, J., Shin, E. H. H., McAvoy, J. W. and Lovicu, F. J. (2011). The fate of dividing cells during lens morphogenesis, differentiation and growth. Exp. Eye Res. 92, 502-511.
    • (2011) Exp. Eye Res. , vol.92 , pp. 502-511
    • Kallifatidis, G.1    Boros, J.2    Shin, E.H.H.3    McAvoy, J.W.4    Lovicu, F.J.5
  • 91
    • 0035873448 scopus 로고    scopus 로고
    • Pax6 and SOX2 form a co-DNA-binding partner complex that regulates initiation of lens development
    • Kamachi, Y., Uchikawa, M., Tanouchi, A., Sekido, R. and Kondoh, H. (2001). Pax6 and SOX2 form a co-DNA-binding partner complex that regulates initiation of lens development. Genes Dev. 15, 1272-1286.
    • (2001) Genes Dev. , vol.15 , pp. 1272-1286
    • Kamachi, Y.1    Uchikawa, M.2    Tanouchi, A.3    Sekido, R.4    Kondoh, H.5
  • 93
    • 84907841711 scopus 로고    scopus 로고
    • AP-2α is required after lens vesicle formation to maintain lens integrity
    • Kerr, C. L., Zaveri, M. A., Robinson, M. L., Williams, T. and West-Mays, J. A. (2014). AP-2α is required after lens vesicle formation to maintain lens integrity. Dev. Dyn. 243, 1298-1309.
    • (2014) Dev. Dyn. , vol.243 , pp. 1298-1309
    • Kerr, C.L.1    Zaveri, M.A.2    Robinson, M.L.3    Williams, T.4    West-Mays, J.A.5
  • 94
    • 0033616621 scopus 로고    scopus 로고
    • Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development
    • Kim, J. I., Li, T., Ho, I.-C., Grusby, M. J. and Glimcher, L. H. (1999). Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development. Proc. Natl. Acad. Sci. USA 96, 3781-3785.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 3781-3785
    • Kim, J.I.1    Li, T.2    Ho, I.-C.3    Grusby, M.J.4    Glimcher, L.H.5
  • 96
    • 84896881296 scopus 로고    scopus 로고
    • Stage-dependent requirement of neuroretinal Pax6 for lens and retina development
    • Klimova, L. and Kozmik, Z. (2014). Stage-dependent requirement of neuroretinal Pax6 for lens and retina development. Development 141, 1292-1302.
    • (2014) Development , vol.141 , pp. 1292-1302
    • Klimova, L.1    Kozmik, Z.2
  • 97
    • 2942536704 scopus 로고    scopus 로고
    • Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein
    • Kowanetz, M., Valcourt, U., Bergstrom, R., Heldin, C.-H. and Moustakas, A. (2004). Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein. Mol. Cell. Biol. 24, 4241-4254.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 4241-4254
    • Kowanetz, M.1    Valcourt, U.2    Bergstrom, R.3    Heldin, C.-H.4    Moustakas, A.5
  • 103
    • 0036137567 scopus 로고    scopus 로고
    • Lens proteomics: Analysis of rat crystallin sequences and two-dimensional electrophoresis map
    • Lampi, K. J., Shih, M., Ueda, Y., Shearer, T. R. and David, L. L. (2002). Lens proteomics: analysis of rat crystallin sequences and two-dimensional electrophoresis map. Invest. Ophthalmol. Vis. Sci. 43, 216-224.
    • (2002) Invest. Ophthalmol. Vis. Sci. , vol.43 , pp. 216-224
    • Lampi, K.J.1    Shih, M.2    Ueda, Y.3    Shearer, T.R.4    David, L.L.5
  • 104
    • 84905474662 scopus 로고    scopus 로고
    • P120-catenin-dependent junctional recruitment of Shroom3 is required for apical constriction during lens pit morphogenesis
    • Lang, R. A., Herman, K., Reynolds, A. B., Hildebrand, J. D. and Plageman, T. F., Jr. (2014). p120-catenin-dependent junctional recruitment of Shroom3 is required for apical constriction during lens pit morphogenesis. Development 141, 3177-3187.
    • (2014) Development , vol.141 , pp. 3177-3187
    • Lang, R.A.1    Herman, K.2    Reynolds, A.B.3    Hildebrand, J.D.4    Plageman, T.F.5
  • 105
    • 61349177856 scopus 로고    scopus 로고
    • Jagged 1 is necessary for normal mouse lens formation
    • Le, T. T., Conley, K. W. and Brown, N. L. (2009). Jagged 1 is necessary for normal mouse lens formation. Dev. Biol. 328, 118-126.
    • (2009) Dev. Biol. , vol.328 , pp. 118-126
    • Le, T.T.1    Conley, K.W.2    Brown, N.L.3
  • 106
    • 84857036238 scopus 로고    scopus 로고
    • Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development
    • Le, T. T., Conley, K. W., Mead, T. J., Rowan, S., Yutzey, K. E. and Brown, N. L. (2012). Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development. Dev. Dyn. 241, 493-504.
    • (2012) Dev. Dyn. , vol.241 , pp. 493-504
    • Le, T.T.1    Conley, K.W.2    Mead, T.J.3    Rowan, S.4    Yutzey, K.E.5    Brown, N.L.6
  • 107
    • 0035827604 scopus 로고    scopus 로고
    • Caspase remodeling of the spectrin membrane skeleton during lens development and aging
    • Lee, A., Morrow, J. S. and Fowler, V. M. (2001). Caspase remodeling of the spectrin membrane skeleton during lens development and aging. J. Biol. Chem. 276, 20735-20742.
    • (2001) J. Biol. Chem. , vol.276 , pp. 20735-20742
    • Lee, A.1    Morrow, J.S.2    Fowler, V.M.3
  • 109
    • 84876502294 scopus 로고    scopus 로고
    • Distinct roles for N-Cadherin linked c-Src and fyn kinases in lens development
    • Leonard, M., Zhang, L., Bleaken, B. M. and Menko, A. S. (2013). Distinct roles for N-Cadherin linked c-Src and fyn kinases in lens development. Dev. Dyn. 242, 469-484.
    • (2013) Dev. Dyn. , vol.242 , pp. 469-484
    • Leonard, M.1    Zhang, L.2    Bleaken, B.M.3    Menko, A.S.4
  • 110
    • 84878819305 scopus 로고    scopus 로고
    • Differential BMP signaling controls formation and differentiation of multipotent preplacodal ectoderm progenitors from human embryonic stem cells
    • Leung, A. W., Kent Morest, D. and Li, J. Y. H. (2013). Differential BMP signaling controls formation and differentiation of multipotent preplacodal ectoderm progenitors from human embryonic stem cells. Dev. Biol. 379, 208-220.
    • (2013) Dev. Biol. , vol.379 , pp. 208-220
    • Leung, A.W.1    Kent Morest, D.2    Li, J.Y.H.3
  • 111
    • 70349116543 scopus 로고    scopus 로고
    • Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development
    • Li, Y. and Piatigorsky, J. (2009). Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development. Dev. Dyn. 238, 2388-2400.
    • (2009) Dev. Dyn. , vol.238 , pp. 2388-2400
    • Li, Y.1    Piatigorsky, J.2
  • 114
    • 27144449720 scopus 로고    scopus 로고
    • A balance of FGF, BMP and WNT signalling positions the future placode territory in the head
    • Litsiou, A., Hanson, S. and Streit, A. (2005). A balance of FGF, BMP and WNT signalling positions the future placode territory in the head. Development 132, 4051-4062.
    • (2005) Development , vol.132 , pp. 4051-4062
    • Litsiou, A.1    Hanson, S.2    Streit, A.3
  • 115
    • 33751109710 scopus 로고    scopus 로고
    • Six3 activation of Pax6 expression is essential for mammalian lens induction and specification
    • Liu,W., Lagutin, O. V., Mende, M., Streit, A. and Oliver, G. (2006). Six3 activation of Pax6 expression is essential for mammalian lens induction and specification. EMBO J. 25, 5383-5395.
    • (2006) EMBO J. , vol.25 , pp. 5383-5395
    • Liu, W.1    Lagutin, O.V.2    Mende, M.3    Streit, A.4    Oliver, G.5
  • 117
    • 0028088752 scopus 로고
    • Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants
    • Lohnes, D., Mark, M., Mendelsohn, C., Dolle, P., Dierich, A., Gorry, P., Gansmuller, A. and Chambon, P. (1994). Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants. Development 120, 2723-2748.
    • (1994) Development , vol.120 , pp. 2723-2748
    • Lohnes, D.1    Mark, M.2    Mendelsohn, C.3    Dolle, P.4    Dierich, A.5    Gorry, P.6    Gansmuller, A.7    Chambon, P.8
  • 118
    • 14844323116 scopus 로고    scopus 로고
    • Growth factor regulation of lens development
    • Lovicu, F. J. and McAvoy, J. W. (2005). Growth factor regulation of lens development. Dev. Biol. 280, 1-14.
    • (2005) Dev. Biol. , vol.280 , pp. 1-14
    • Lovicu, F.J.1    McAvoy, J.W.2
  • 119
    • 0028882261 scopus 로고
    • BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning
    • Luo, G., Hofmann, C., Bronckers, A. L., Sohocki, M., Bradley, A. and Karsenty, G. (1995). BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning. Genes Dev. 9, 2808-2820.
    • (1995) Genes Dev. , vol.9 , pp. 2808-2820
    • Luo, G.1    Hofmann, C.2    Bronckers, A.L.3    Sohocki, M.4    Bradley, A.5    Karsenty, G.6
  • 121
    • 80755153156 scopus 로고    scopus 로고
    • Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival
    • Maddala, R., Chauhan, B. K.,Walker, C., Zheng, Y., Robinson, M. L., Lang, R. A. and Rao, P. V. (2011). Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival. Dev. Biol. 360, 30-43.
    • (2011) Dev. Biol. , vol.360 , pp. 30-43
    • Maddala, R.1    Chauhan, B.K.2    Walker, C.3    Zheng, Y.4    Robinson, M.L.5    Lang, R.A.6    Rao, P.V.7
  • 125
    • 78149279865 scopus 로고    scopus 로고
    • The lens epithelium in ocular health and disease
    • Martinez, G. and de Iongh, R. U. (2010). The lens epithelium in ocular health and disease. Int. J. Biochem. Cell Biol. 42, 1945-1963.
    • (2010) Int. J. Biochem. Cell Biol. , vol.42 , pp. 1945-1963
    • Martinez, G.1    de Iongh, R.U.2
  • 126
    • 27644494876 scopus 로고    scopus 로고
    • Smad transcription factors
    • Massague, J., Seoane, J. and Wotton, D. (2005). Smad transcription factors. Genes Dev. 19, 2783-2810.
    • (2005) Genes Dev. , vol.19 , pp. 2783-2810
    • Massague, J.1    Seoane, J.2    Wotton, D.3
  • 127
    • 0031001710 scopus 로고    scopus 로고
    • The Rx homeobox gene is essential for vertebrate eye development
    • Mathers, P. H., Grinberg, A., Mahon, K. A. and Jamrich, M. (1997). The Rx homeobox gene is essential for vertebrate eye development. Nature 387, 603-607.
    • (1997) Nature , vol.387 , pp. 603-607
    • Mathers, P.H.1    Grinberg, A.2    Mahon, K.A.3    Jamrich, M.4
  • 128
    • 74949108062 scopus 로고    scopus 로고
    • Lens gap junctions in growth, differentiation, and homeostasis
    • Mathias, R. T., White, T. W. and Gong, X. (2010). Lens gap junctions in growth, differentiation, and homeostasis. Physiol. Rev. 90, 179-206.
    • (2010) Physiol. Rev. , vol.90 , pp. 179-206
    • Mathias, R.T.1    White, T.W.2    Gong, X.3
  • 129
    • 0019162286 scopus 로고
    • Cytoplasmic processes interconnect lens placode and optic vesicle during eye morphogenesis
    • McAvoy, J. W. (1980). Cytoplasmic processes interconnect lens placode and optic vesicle during eye morphogenesis. Exp. Eye Res. 31, 527-534.
    • (1980) Exp. Eye Res. , vol.31 , pp. 527-534
    • McAvoy, J.W.1
  • 130
    • 0024458628 scopus 로고
    • Fibroblast growth factor (FGF) induces different responses in lens epithelial cells depending on its concentration
    • McAvoy, J. W. and Chamberlain, C. G. (1989). Fibroblast growth factor (FGF) induces different responses in lens epithelial cells depending on its concentration. Development 107, 221-228.
    • (1989) Development , vol.107 , pp. 221-228
    • McAvoy, J.W.1    Chamberlain, C.G.2
  • 131
    • 67650960646 scopus 로고    scopus 로고
    • Molecular and tissue interactions governing induction of cranial ectodermal placodes
    • McCabe, K. L. and Bronner-Fraser, M. (2009). Molecular and tissue interactions governing induction of cranial ectodermal placodes. Dev. Biol. 332, 189-195.
    • (2009) Dev. Biol. , vol.332 , pp. 189-195
    • McCabe, K.L.1    Bronner-Fraser, M.2
  • 133
    • 70349091843 scopus 로고    scopus 로고
    • Pitx3 controls multiple aspects of lens development
    • Medina-Martinez, O., Shah, R. and Jamrich, M. (2009). Pitx3 controls multiple aspects of lens development. Dev. Dyn. 238, 2193-2201.
    • (2009) Dev. Dyn. , vol.238 , pp. 2193-2201
    • Medina-Martinez, O.1    Shah, R.2    Jamrich, M.3
  • 134
    • 4544362797 scopus 로고    scopus 로고
    • Raldh2 expression in optic vesicle generates a retinoic acid signal needed for invagination of retina during optic cup formation
    • Mic, F. A., Molotkov, A., Molotkova, N. and Duester, G. (2004). Raldh2 expression in optic vesicle generates a retinoic acid signal needed for invagination of retina during optic cup formation. Dev. Dyn. 231, 270-277.
    • (2004) Dev. Dyn. , vol.231 , pp. 270-277
    • Mic, F.A.1    Molotkov, A.2    Molotkova, N.3    Duester, G.4
  • 135
    • 0033591344 scopus 로고    scopus 로고
    • Phosphorylation of the transactivation domain of Pax6 by extracellular signalregulated kinase and p38 mitogen-activated protein kinase
    • Mikkola, I., Bruun, J.-A., Bjorkoy, G., Holm, T. and Johansen, T. (1999). Phosphorylation of the transactivation domain of Pax6 by extracellular signalregulated kinase and p38 mitogen-activated protein kinase. J. Biol. Chem. 274, 15115-15126.
    • (1999) J. Biol. Chem. , vol.274 , pp. 15115-15126
    • Mikkola, I.1    Bruun, J.-A.2    Bjorkoy, G.3    Holm, T.4    Johansen, T.5
  • 136
    • 33745093456 scopus 로고    scopus 로고
    • Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning
    • Molotkov, A., Molotkova, N. and Duester, G. (2006). Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning. Development 133, 1901-1910.
    • (2006) Development , vol.133 , pp. 1901-1910
    • Molotkov, A.1    Molotkova, N.2    Duester, G.3
  • 138
    • 0027934570 scopus 로고
    • P53- dependent apoptosis produced by Rb-deficiency in the developing mouse lens
    • Morgenbesser, S. D., Williams, B. O., Jacks, T. and DePinho, R. A. (1994). p53- dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature 371, 72-74.
    • (1994) Nature , vol.371 , pp. 72-74
    • Morgenbesser, S.D.1    Williams, B.O.2    Jacks, T.3    DePinho, R.A.4
  • 139
    • 33645538666 scopus 로고    scopus 로고
    • Caspase-dependent secondary lens fiber cell disintegration in αA-/αB-crystallin double-knockout mice
    • Morozov, V. and Wawrousek, E. F. (2006). Caspase-dependent secondary lens fiber cell disintegration in αA-/αB-crystallin double-knockout mice. Development 133, 813-821.
    • (2006) Development , vol.133 , pp. 813-821
    • Morozov, V.1    Wawrousek, E.F.2
  • 140
    • 0036546980 scopus 로고    scopus 로고
    • Neural induction, the default model and embryonic stem cells
    • Muñoz-Sanjuán, I. and Brivanlou, A. H. (2002). Neural induction, the default model and embryonic stem cells. Nat. Rev. Neurosci. 3, 271-280.
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 271-280
    • Muñoz-Sanjuán, I.1    Brivanlou, A.H.2
  • 141
    • 0029010352 scopus 로고
    • An apoptotic defect in lens differentiation caused by human p53 is rescued by a mutant allele
    • Nakamura, T., Pichel, J. G., Williams-Simons, L. and Westphal, H. (1995). An apoptotic defect in lens differentiation caused by human p53 is rescued by a mutant allele. Proc. Natl. Acad. Sci. USA 92, 6142-6146.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 6142-6146
    • Nakamura, T.1    Pichel, J.G.2    Williams-Simons, L.3    Westphal, H.4
  • 142
    • 84902455485 scopus 로고    scopus 로고
    • Crystallin-αB regulates skeletal muscle homeostasis via modulation of argonaute2 activity
    • Neppl, R. L., Kataoka, M. and Wang, D.-Z. (2014). Crystallin-αB regulates skeletal muscle homeostasis via modulation of argonaute2 activity. J. Biol. Chem. 289, 17240-17248.
    • (2014) J. Biol. Chem. , vol.289 , pp. 17240-17248
    • Neppl, R.L.1    Kataoka, M.2    Wang, D.-Z.3
  • 147
    • 38949142986 scopus 로고    scopus 로고
    • Convergence of a head-field selector Otx2 and Notch signaling: A mechanism for lens specification
    • Ogino, H., Fisher, M. and Grainger, R. M. (2008). Convergence of a head-field selector Otx2 and Notch signaling: a mechanism for lens specification. Development 135, 249-258.
    • (2008) Development , vol.135 , pp. 249-258
    • Ogino, H.1    Fisher, M.2    Grainger, R.M.3
  • 148
    • 0030790020 scopus 로고    scopus 로고
    • Current views on eye development
    • Oliver, G. and Gruss, P. (1997). Current views on eye development. Trends Neurosci. 20, 415-421.
    • (1997) Trends Neurosci. , vol.20 , pp. 415-421
    • Oliver, G.1    Gruss, P.2
  • 150
    • 0022351502 scopus 로고
    • Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine αA-crystallin promoter in transgenic mice
    • Overbeek, P. A., Chepelinsky, A. B., Khillan, J. S., Piatigorsky, J. andWestphal, H. (1985). Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine αA-crystallin promoter in transgenic mice. Proc. Natl. Acad. Sci. USA 82, 7815-7819.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 7815-7819
    • Overbeek, P.A.1    Chepelinsky, A.B.2    Khillan, J.S.3    Piatigorsky, J.4    Westphal, H.5
  • 151
    • 0028334011 scopus 로고
    • Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function in development
    • Pan, H. and Griep, A. E. (1994). Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development. Genes Dev. 8, 1285-1299.
    • (1994) Genes Dev. , vol.8 , pp. 1285-1299
    • Pan, H.1    Griep, A.E.2
  • 152
    • 0029093605 scopus 로고
    • Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development
    • Pan, H. and Griep, A. E. (1995). Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development. Genes Dev. 9, 2157-2169.
    • (1995) Genes Dev. , vol.9 , pp. 2157-2169
    • Pan, H.1    Griep, A.E.2
  • 153
    • 33846157731 scopus 로고    scopus 로고
    • Heparan sulfate biosynthetic gene Ndst1 is required for FGF signaling in early lens development
    • Pan, Y., Woodbury, A., Esko, J. D., Grobe, K. and Zhang, X. (2006). Heparan sulfate biosynthetic gene Ndst1 is required for FGF signaling in early lens development. Development 133, 4933-4944.
    • (2006) Development , vol.133 , pp. 4933-4944
    • Pan, Y.1    Woodbury, A.2    Esko, J.D.3    Grobe, K.4    Zhang, X.5
  • 154
    • 84892548031 scopus 로고    scopus 로고
    • Signaling pathways regulating ectodermal cell fate choices
    • Patthey, C. and Gunhaga, L. (2014). Signaling pathways regulating ectodermal cell fate choices. Exp. Cell Res. 321, 11-16.
    • (2014) Exp. Cell Res. , vol.321 , pp. 11-16
    • Patthey, C.1    Gunhaga, L.2
  • 155
    • 84890399697 scopus 로고    scopus 로고
    • Aging and age-related diseases of the ocular lens and vitreous body
    • Petrash, J. M. (2013). Aging and age-related diseases of the ocular lens and vitreous body. Invest. Ophthalmol. Vis. Sci. 54, ORSF54-ORSF59.
    • (2013) Invest. Ophthalmol. Vis. Sci. , vol.54 , pp. ORSF54-ORSF59
    • Petrash, J.M.1
  • 156
    • 0019786296 scopus 로고
    • Lens differentiation in vertebrates. A review of cellular and molecular features
    • Piatigorsky, J. (1981). Lens differentiation in vertebrates. A review of cellular and molecular features. Differentiation 19, 134-153.
    • (1981) Differentiation , vol.19 , pp. 134-153
    • Piatigorsky, J.1
  • 157
  • 160
    • 58649124705 scopus 로고    scopus 로고
    • Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival
    • Pontoriero, G. F., Smith, A. N., Miller, L.-A. D., Radice, G. L., West-Mays, J. A. and Lang, R. A. (2009). Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival. Dev. Biol. 326, 403-417.
    • (2009) Dev. Biol. , vol.326 , pp. 403-417
    • Pontoriero, G.F.1    Smith, A.N.2    Miller, L.-A.D.3    Radice, G.L.4    West-Mays, J.A.5    Lang, R.A.6
  • 162
    • 84876888289 scopus 로고    scopus 로고
    • Epigenetics: Core misconcept
    • Ptashne, M. (2013). Epigenetics: core misconcept. Proc. Natl. Acad. Sci. USA 110, 7101-7103.
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 7101-7103
    • Ptashne, M.1
  • 163
    • 29244442592 scopus 로고    scopus 로고
    • Pax6- dependence of Six3, Eya1 and Dach1 expression during lens and nasal placode induction
    • Purcell, P., Oliver, G., Mardon, G., Donner, A. L. and Maas, R. L. (2005). Pax6- dependence of Six3, Eya1 and Dach1 expression during lens and nasal placode induction. Gene Expr. Patterns 6, 110-118.
    • (2005) Gene Expr. Patterns , vol.6 , pp. 110-118
    • Purcell, P.1    Oliver, G.2    Mardon, G.3    Donner, A.L.4    Maas, R.L.5
  • 164
    • 79957627442 scopus 로고    scopus 로고
    • Genetic epistasis between heparan sulfate and FGF-Ras signaling controls lens development
    • Qu, X., Hertzler, K., Pan, Y., Grobe, K., Robinson, M. L. and Zhang, X. (2011). Genetic epistasis between heparan sulfate and FGF-Ras signaling controls lens development. Dev. Biol. 355, 12-20.
    • (2011) Dev. Biol. , vol.355 , pp. 12-20
    • Qu, X.1    Hertzler, K.2    Pan, Y.3    Grobe, K.4    Robinson, M.L.5    Zhang, X.6
  • 165
    • 0029979219 scopus 로고    scopus 로고
    • Multiple functions for Pax6 in mouse eye and nasal development
    • Quinn, J. C.,West, J. D. and Hill, R. E. (1996). Multiple functions for Pax6 in mouse eye and nasal development. Genes Dev. 10, 435-446.
    • (1996) Genes Dev. , vol.10 , pp. 435-446
    • Quinn, J.C.1    West, J.D.2    Hill, R.E.3
  • 169
    • 33846339788 scopus 로고    scopus 로고
    • The role of the lens actin cytoskeleton in fiber cell elongation and differentiation
    • Rao, P. V. and Maddala, R. (2006). The role of the lens actin cytoskeleton in fiber cell elongation and differentiation. Semin. Cell Dev. Biol. 17, 698-711.
    • (2006) Semin. Cell Dev. Biol. , vol.17 , pp. 698-711
    • Rao, P.V.1    Maddala, R.2
  • 171
    • 0033967140 scopus 로고    scopus 로고
    • Regulation of mouse lens fiber cell development and differentiation by the Maf gene
    • Ring, B. Z., Cordes, S. P., Overbeek, P. A. and Barsh, G. S. (2000). Regulation of mouse lens fiber cell development and differentiation by the Maf gene. Development 127, 307-317.
    • (2000) Development , vol.127 , pp. 307-317
    • Ring, B.Z.1    Cordes, S.P.2    Overbeek, P.A.3    Barsh, G.S.4
  • 172
    • 70349160842 scopus 로고    scopus 로고
    • Cell-autonomous requirements for Dlg-1 for lens epithelial cell structure and fiber cell morphogenesis
    • Rivera, C., Yamben, I. F., Shatadal, S., Waldof, M., Robinson, M. L. and Griep, A. E. (2009). Cell-autonomous requirements for Dlg-1 for lens epithelial cell structure and fiber cell morphogenesis. Dev. Dyn. 238, 2292-2308.
    • (2009) Dev. Dyn. , vol.238 , pp. 2292-2308
    • Rivera, C.1    Yamben, I.F.2    Shatadal, S.3    Waldof, M.4    Robinson, M.L.5    Griep, A.E.6
  • 173
    • 49249137030 scopus 로고    scopus 로고
    • Notch signaling regulates growth and differentiation in the mammalian lens
    • Rowan, S., Conley, K. W., Le, T. T., Donner, A. L., Maas, R. L. and Brown, N. L. (2008). Notch signaling regulates growth and differentiation in the mammalian lens. Dev. Biol. 321, 111-122.
    • (2008) Dev. Biol. , vol.321 , pp. 111-122
    • Rowan, S.1    Conley, K.W.2    Le, T.T.3    Donner, A.L.4    Maas, R.L.5    Brown, N.L.6
  • 174
    • 77952352833 scopus 로고    scopus 로고
    • Precise temporal control of the eye regulatory gene Pax6 via enhancerbinding site affinity
    • Rowan, S., Siggers, T., Lachke, S. A., Yue, Y., Bulyk, M. L. and Maas, R. L. (2010). Precise temporal control of the eye regulatory gene Pax6 via enhancerbinding site affinity. Genes Dev. 24, 980-985.
    • (2010) Genes Dev. , vol.24 , pp. 980-985
    • Rowan, S.1    Siggers, T.2    Lachke, S.A.3    Yue, Y.4    Bulyk, M.L.5    Maas, R.L.6
  • 179
    • 0030669179 scopus 로고    scopus 로고
    • Isolation of a new homeobox gene belonging to the Pitx/Rieg family: Expression during lens development and mapping to the aphakia region on mouse chromosome 19
    • Semina, E. V., Reiter, R. S. and Murray, J. C. (1997). Isolation of a new homeobox gene belonging to the Pitx/Rieg family: expression during lens development and mapping to the aphakia region on mouse chromosome 19. Hum. Mol. Genet. 6, 2109-2116.
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 2109-2116
    • Semina, E.V.1    Reiter, R.S.2    Murray, J.C.3
  • 180
    • 84892672044 scopus 로고    scopus 로고
    • Expression of the de novo DNA methyltransferases (dnmt3 - dnmt8) during zebrafish lens development
    • Seritrakul, P. and Gross, J. M. (2014). Expression of the de novo DNA methyltransferases (dnmt3 - dnmt8) during zebrafish lens development. Dev. Dyn. 243, 350-356.
    • (2014) Dev. Dyn. , vol.243 , pp. 350-356
    • Seritrakul, P.1    Gross, J.M.2
  • 186
    • 0030031158 scopus 로고    scopus 로고
    • Mutations in the founder of the MIP gene family underlie cataract development in the mouse
    • Shiels, A. and Bassnett, S. (1996). Mutations in the founder of the MIP gene family underlie cataract development in the mouse. Nat. Genet. 12, 212-215.
    • (1996) Nat. Genet. , vol.12 , pp. 212-215
    • Shiels, A.1    Bassnett, S.2
  • 187
    • 84880154660 scopus 로고    scopus 로고
    • Genetics of human cataract
    • Shiels, A. and Hejtmancik, J. F. (2013). Genetics of human cataract. Clin. Genet. 84, 120-127.
    • (2013) Clin. Genet. , vol.84 , pp. 120-127
    • Shiels, A.1    Hejtmancik, J.F.2
  • 189
    • 34250904130 scopus 로고    scopus 로고
    • Time of exposure to BMP signals plays a key role in the specification of the olfactory and lens placodes ex vivo
    • Sjödal, M., Edlund, T. and Gunhaga, L. (2007). Time of exposure to BMP signals plays a key role in the specification of the olfactory and lens placodes ex vivo. Dev. Cell 13, 141-149.
    • (2007) Dev. Cell , vol.13 , pp. 141-149
    • Sjödal, M.1    Edlund, T.2    Gunhaga, L.3
  • 190
    • 25844490866 scopus 로고    scopus 로고
    • The duality of β-catenin function: A requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm
    • Smith, A. N., Miller, L.-A. D., Song, N., Taketo, M. M. and Lang, R. A. (2005). The duality of β-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm. Dev. Biol. 285, 477-489.
    • (2005) Dev. Biol. , vol.285 , pp. 477-489
    • Smith, A.N.1    Miller, L.-A.D.2    Song, N.3    Taketo, M.M.4    Lang, R.A.5
  • 191
    • 69049119231 scopus 로고    scopus 로고
    • Stage-dependent modes of Pax6-Sox2 epistasis regulate lens development and eye morphogenesis
    • Smith, A. N., Miller, L.-A., Radice, G., Ashery-Padan, R. and Lang, R. A. (2009). Stage-dependent modes of Pax6-Sox2 epistasis regulate lens development and eye morphogenesis. Development 136, 2977-2985.
    • (2009) Development , vol.136 , pp. 2977-2985
    • Smith, A.N.1    Miller, L.-A.2    Radice, G.3    Ashery-Padan, R.4    Lang, R.A.5
  • 193
    • 84892897064 scopus 로고    scopus 로고
    • Dual function of Yap in the regulation of lens progenitor cells and cellular polarity
    • Song, J. Y., Park, R., Kim, J. Y., Hughes, L., Lu, L., Kim, S., Johnson, R. L. and Cho, S.-H. (2014). Dual function of Yap in the regulation of lens progenitor cells and cellular polarity. Dev. Biol. 386, 281-290.
    • (2014) Dev. Biol. , vol.386 , pp. 281-290
    • Song, J.Y.1    Park, R.2    Kim, J.Y.3    Hughes, L.4    Lu, L.5    Kim, S.6    Johnson, R.L.7    Cho, S.-H.8
  • 194
    • 79959200303 scopus 로고    scopus 로고
    • MIP/ Aquaporin 0 represents a direct transcriptional target of PITX3 in the developing lens
    • Sorokina, E. A., Muheisen, S., Mlodik, N. and Semina, E. V. (2011). MIP/ Aquaporin 0 represents a direct transcriptional target of PITX3 in the developing lens. PLoS ONE 6, e21122.
    • (2011) PLoS ONE , vol.6
    • Sorokina, E.A.1    Muheisen, S.2    Mlodik, N.3    Semina, E.V.4
  • 196
    • 84861699723 scopus 로고    scopus 로고
    • Mutual repression between Gbx2 and Otx2 in sensory placodes reveals a general mechanism for ectodermal patterning
    • Steventon, B., Mayor, R. and Streit, A. (2012). Mutual repression between Gbx2 and Otx2 in sensory placodes reveals a general mechanism for ectodermal patterning. Dev. Biol. 367, 55-65.
    • (2012) Dev. Biol. , vol.367 , pp. 55-65
    • Steventon, B.1    Mayor, R.2    Streit, A.3
  • 197
    • 70449526292 scopus 로고    scopus 로고
    • A cell polarity protein aPKClambda is required for eye lens formation and growth
    • Sugiyama, Y., Akimoto, K., Robinson, M. L., Ohno, S. and Quinlan, R. A. (2009). A cell polarity protein aPKClambda is required for eye lens formation and growth. Dev. Biol. 336, 246-256.
    • (2009) Dev. Biol. , vol.336 , pp. 246-256
    • Sugiyama, Y.1    Akimoto, K.2    Robinson, M.L.3    Ohno, S.4    Quinlan, R.A.5
  • 198
  • 199
    • 84863566216 scopus 로고    scopus 로고
    • Planar cell polarity in the mammalian eye lens
    • Sugiyama, Y., Lovicu, F. J. and McAvoy, J. W. (2011). Planar cell polarity in the mammalian eye lens. Organogenesis 7, 191-201.
    • (2011) Organogenesis , vol.7 , pp. 191-201
    • Sugiyama, Y.1    Lovicu, F.J.2    McAvoy, J.W.3
  • 203
    • 75149170979 scopus 로고    scopus 로고
    • Fibroblast growth factor signalling: From development to cancer
    • Turner, N. and Grose, R. (2010). Fibroblast growth factor signalling: from development to cancer. Nat. Rev. Cancer 10, 116-129.
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 116-129
    • Turner, N.1    Grose, R.2
  • 204
    • 84875059948 scopus 로고    scopus 로고
    • MAPK1 is required for establishing the pattern of cell proliferation and for cell survival during lens development
    • Upadhya, D., Ogata, M. and Reneker, L. W. (2013). MAPK1 is required for establishing the pattern of cell proliferation and for cell survival during lens development. Development 140, 1573-1582.
    • (2013) Development , vol.140 , pp. 1573-1582
    • Upadhya, D.1    Ogata, M.2    Reneker, L.W.3
  • 205
    • 84896903811 scopus 로고    scopus 로고
    • Lysosomalmediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling
    • Valapala, M., Wilson, C., Hose, S., Bhutto, I. A., Grebe, R., Dong, A., Greenbaum, S., Gu, L., Sengupta, S., Cano, M. et al. (2014). Lysosomalmediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling. Autophagy 10, 480-496.
    • (2014) Autophagy , vol.10 , pp. 480-496
    • Valapala, M.1    Wilson, C.2    Hose, S.3    Bhutto, I.A.4    Grebe, R.5    Dong, A.6    Greenbaum, S.7    Gu, L.8    Sengupta, S.9    Cano, M.10
  • 206
    • 0032563812 scopus 로고    scopus 로고
    • A function for lipoxygenase in programmed organelle degradation
    • van Leyen, K., Duvoisin, R. M., Engelhardt, H. and Wiedmann, M. (1998). A function for lipoxygenase in programmed organelle degradation. Nature 395, 392-395.
    • (1998) Nature , vol.395 , pp. 392-395
    • van Leyen, K.1    Duvoisin, R.M.2    Engelhardt, H.3    Wiedmann, M.4
  • 207
    • 0034526271 scopus 로고    scopus 로고
    • Dosage requirement and allelic expression of PAX6 during lens placode formation
    • van Raamsdonk, C. D. and Tilghman, S. M. (2000). Dosage requirement and allelic expression of PAX6 during lens placode formation. Development 127, 5439-5448.
    • (2000) Development , vol.127 , pp. 5439-5448
    • van Raamsdonk, C.D.1    Tilghman, S.M.2
  • 209
    • 0026340588 scopus 로고
    • Pax-6, a murine paired box gene, is expressed in the developing CNS
    • Walther, C. and Gruss, P. (1991). Pax-6, a murine paired box gene, is expressed in the developing CNS. Development 113, 1435-1449.
    • (1991) Development , vol.113 , pp. 1435-1449
    • Walther, C.1    Gruss, P.2
  • 211
    • 77954626704 scopus 로고    scopus 로고
    • Lens fiber cell differentiation and denucleation are disrupted through expression of the N-terminal nuclear receptor box of NCOA6 and result in p53-dependent and p53-independent apoptosis
    • Wang, W.-L., Li, Q., Xu, J. and Cvekl, A. (2010). Lens fiber cell differentiation and denucleation are disrupted through expression of the N-terminal nuclear receptor box of NCOA6 and result in p53-dependent and p53-independent apoptosis. Mol. Biol. Cell 21, 2453-2468.
    • (2010) Mol. Biol. Cell , vol.21 , pp. 2453-2468
    • Wang, W.-L.1    Li, Q.2    Xu, J.3    Cvekl, A.4
  • 212
    • 84874976592 scopus 로고    scopus 로고
    • Proteomics and phosphoproteomics analysis of human lens fiber cell membranes
    • Wang, Z., Han, J., David, L. L. and Schey, K. L. (2013). Proteomics and phosphoproteomics analysis of human lens fiber cell membranes. Invest. Ophthalmol. Vis. Sci. 54, 1135-1143.
    • (2013) Invest. Ophthalmol. Vis. Sci. , vol.54 , pp. 1135-1143
    • Wang, Z.1    Han, J.2    David, L.L.3    Schey, K.L.4
  • 214
    • 84897414264 scopus 로고    scopus 로고
    • FOXO transcription factors: Key regulators of cellular quality control
    • Webb, A. E. and Brunet, A. (2014). FOXO transcription factors: key regulators of cellular quality control. Trends Biochem. Sci. 39, 159-169.
    • (2014) Trends Biochem. Sci. , vol.39 , pp. 159-169
    • Webb, A.E.1    Brunet, A.2
  • 215
    • 20444498637 scopus 로고    scopus 로고
    • The canonical intrinsic mitochondrial death pathway has a non-apoptotic role in signaling lens cell differentiation
    • Weber, G. F. and Menko, A. S. (2005). The canonical intrinsic mitochondrial death pathway has a non-apoptotic role in signaling lens cell differentiation. J. Biol. Chem. 280, 22135-22145.
    • (2005) J. Biol. Chem. , vol.280 , pp. 22135-22145
    • Weber, G.F.1    Menko, A.S.2
  • 216
    • 33746944022 scopus 로고    scopus 로고
    • Actin filament organization regulates the induction of lens cell differentiation and survival
    • Weber, G. F. and Menko, A. S. (2006a). Actin filament organization regulates the induction of lens cell differentiation and survival. Dev. Biol. 295, 714-729.
    • (2006) Dev. Biol. , vol.295 , pp. 714-729
    • Weber, G.F.1    Menko, A.S.2
  • 217
    • 33750579674 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase is necessary for lens fiber cell differentiation and survival
    • Weber, G. F. and Menko, A. S. (2006b). Phosphatidylinositol 3-kinase is necessary for lens fiber cell differentiation and survival. Invest. Ophthalmol. Vis. Sci. 47, 4490-4499.
    • (2006) Invest. Ophthalmol. Vis. Sci. , vol.47 , pp. 4490-4499
    • Weber, G.F.1    Menko, A.S.2
  • 218
    • 0038625108 scopus 로고    scopus 로고
    • JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure
    • Weston, C. R.,Wong, A., Hall, J. P., Goad, M. E. P., Flavell, R. A. and Davis, R. J. (2003). JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure. Genes Dev. 17, 1271-1280.
    • (2003) Genes Dev. , vol.17 , pp. 1271-1280
    • Weston, C.R.1    Wong, A.2    Hall, J.P.3    Goad, M.E.P.4    Flavell, R.A.5    Davis, R.J.6
  • 219
    • 0033832853 scopus 로고    scopus 로고
    • The olfactory placodes of the zebrafish form by convergence of cellular fields at the edge of the neural plate
    • Whitlock, K. E. andWesterfield, M. (2000). The olfactory placodes of the zebrafish form by convergence of cellular fields at the edge of the neural plate. Development 127, 3645-3653.
    • (2000) Development , vol.127 , pp. 3645-3653
    • Whitlock, K.E.1    Westerfield, M.2
  • 220
    • 0033018615 scopus 로고    scopus 로고
    • Prox1 function is crucial for mouse lens-fibre elongation
    • Wigle, J. T., Chowdhury, K., Gruss, P. and Oliver, G. (1999). Prox1 function is crucial for mouse lens-fibre elongation. Nat. Genet. 21, 318-322.
    • (1999) Nat. Genet. , vol.21 , pp. 318-322
    • Wigle, J.T.1    Chowdhury, K.2    Gruss, P.3    Oliver, G.4
  • 221
    • 79959680172 scopus 로고    scopus 로고
    • The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens
    • Wiley, L. A., Rajagopal, R., Dattilo, L. K. and Beebe, D. C. (2011). The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens. Dis. Model. Mech. 4, 484-495.
    • (2011) Dis. Model. Mech. , vol.4 , pp. 484-495
    • Wiley, L.A.1    Rajagopal, R.2    Dattilo, L.K.3    Beebe, D.C.4
  • 222
    • 84907326425 scopus 로고    scopus 로고
    • The genetic architecture of microphthalmia, anophthalmia and coloboma
    • Williamson, K. A. and FitzPatrick, D. R. (2014). The genetic architecture of microphthalmia, anophthalmia and coloboma. Eur. J. Med. Genet. 57, 369-380.
    • (2014) Eur. J. Med. Genet. , vol.57 , pp. 369-380
    • Williamson, K.A.1    FitzPatrick, D.R.2
  • 225
    • 84890420625 scopus 로고    scopus 로고
    • Histone posttranslational modifications and cell fate determination: Lens induction requires the lysine acetyltransferases CBP and p300
    • Wolf, L., Harrison, W., Huang, J., Xie, Q., Xiao, N., Sun, J., Kong, L., Lachke, S. A., Kuracha, M. R., Govindarajan, V. et al. (2013b). Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300. Nucleic Acids Res. 41, 10199-10214.
    • (2013) Nucleic Acids Res. , vol.41 , pp. 10199-10214
    • Wolf, L.1    Harrison, W.2    Huang, J.3    Xie, Q.4    Xiao, N.5    Sun, J.6    Kong, L.7    Lachke, S.A.8    Kuracha, M.R.9    Govindarajan, V.10
  • 226
    • 44649198515 scopus 로고    scopus 로고
    • Anterior segment dysgenesis in the eyes of mice deficient for the high-mobility-group transcription factor Sox11
    • Wurm, A., Sock, E., Fuchshofer, R.,Wegner, M. and Tamm, E. R. (2008). Anterior segment dysgenesis in the eyes of mice deficient for the high-mobility-group transcription factor Sox11. Exp. Eye Res. 86, 895-907.
    • (2008) Exp. Eye Res. , vol.86 , pp. 895-907
    • Wurm, A.1    Sock, E.2    Fuchshofer, R.3    Wegner, M.4    Tamm, E.R.5
  • 227
    • 33744475377 scopus 로고    scopus 로고
    • α-crystallin expression affects microtubule assembly and prevents their aggregation
    • Xi, J.-H., Bai, F., McGaha, R. and Andley, U. P. (2006). α-crystallin expression affects microtubule assembly and prevents their aggregation. FASEB J. 20, 846-857.
    • (2006) FASEB J. , vol.20 , pp. 846-857
    • Xi, J.-H.1    Bai, F.2    McGaha, R.3    Andley, U.P.4
  • 228
    • 83355166954 scopus 로고    scopus 로고
    • The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops
    • Xie, Q. and Cvekl, A. (2011). The orchestration of mammalian tissue morphogenesis through a series of coherent feed-forward loops. J. Biol. Chem. 286, 43259-43271.
    • (2011) J. Biol. Chem. , vol.286 , pp. 43259-43271
    • Xie, Q.1    Cvekl, A.2
  • 229
    • 0029009621 scopus 로고
    • Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres
    • Xuan, S., Baptista, C. A., Balas, G., Tao, W., Soares, V. C. and Lai, E. (1995). Winged helix transcription factor BF-1 is essential for the development of the cerebral hemispheres. Neuron 14, 1141-1152.
    • (1995) Neuron , vol.14 , pp. 1141-1152
    • Xuan, S.1    Baptista, C.A.2    Balas, G.3    Tao, W.4    Soares, V.C.5    Lai, E.6
  • 230
  • 231
    • 4644367927 scopus 로고    scopus 로고
    • Requirement for Mab21l2 during development of murine retina and ventral body wall
    • Yamada, R., Mizutani-Koseki, Y., Koseki, H. and Takahashi, N. (2004). Requirement for Mab21l2 during development of murine retina and ventral body wall. Dev. Biol. 274, 295-307.
    • (2004) Dev. Biol. , vol.274 , pp. 295-307
    • Yamada, R.1    Mizutani-Koseki, Y.2    Koseki, H.3    Takahashi, N.4
  • 232
    • 84886948428 scopus 로고    scopus 로고
    • Scrib is required for epithelial cell identity and prevents epithelial to mesenchymal transition in the mouse
    • Yamben, I. F., Rachel, R. A., Shatadal, S., Copeland, N. G., Jenkins, N. A., Warming, S. and Griep, A. E. (2013). Scrib is required for epithelial cell identity and prevents epithelial to mesenchymal transition in the mouse. Dev. Biol. 384, 41-52.
    • (2013) Dev. Biol. , vol.384 , pp. 41-52
    • Yamben, I.F.1    Rachel, R.A.2    Shatadal, S.3    Copeland, N.G.4    Jenkins, N.A.5    Warming, S.6    Griep, A.E.7
  • 233
    • 34347240393 scopus 로고    scopus 로고
    • Protein phosphatase-1 modulates the function of Pax-6, a transcription factor controlling brain and eye development
    • Yan, Q., Liu, W.-B., Qin, J., Liu, J., Chen, H.-G., Huang, X., Chen, L., Sun, S., Deng, M., Gong, L. et al. (2007). Protein phosphatase-1 modulates the function of Pax-6, a transcription factor controlling brain and eye development. J. Biol. Chem. 282, 13954-13965.
    • (2007) J. Biol. Chem. , vol.282 , pp. 13954-13965
    • Yan, Q.1    Liu, W.-B.2    Qin, J.3    Liu, J.4    Chen, H.-G.5    Huang, X.6    Chen, L.7    Sun, S.8    Deng, M.9    Gong, L.10
  • 235
    • 33746367158 scopus 로고    scopus 로고
    • A novel function of DNA repair molecule Nbs1 in terminal differentiation of the lens fibre cells and cataractogenesis
    • Yang, Y.-G., Frappart, P.-O., Frappart, L., Wang, Z.-Q. and Tong, W.-M. (2006b). A novel function of DNA repair molecule Nbs1 in terminal differentiation of the lens fibre cells and cataractogenesis. DNA Repair (Amst.) 5, 885-893.
    • (2006) DNA Repair (Amst.) , vol.5 , pp. 885-893
    • Yang, Y.-G.1    Frappart, P.-O.2    Frappart, L.3    Wang, Z.-Q.4    Tong, W.-M.5
  • 236
    • 77956634746 scopus 로고    scopus 로고
    • Efficient generation of lens progenitor cells and lentoid bodies fromhuman embryonic stem cells in chemically defined conditions
    • Yang, C., Yang, Y., Brennan, L., Bouhassira, E. E., Kantorow, M. and Cvekl, A. (2010). Efficient generation of lens progenitor cells and lentoid bodies fromhuman embryonic stem cells in chemically defined conditions. FASEB J. 24, 3274-3283.
    • (2010) FASEB J. , vol.24 , pp. 3274-3283
    • Yang, C.1    Yang, Y.2    Brennan, L.3    Bouhassira, E.E.4    Kantorow, M.5    Cvekl, A.6
  • 237
    • 81855211038 scopus 로고    scopus 로고
    • Fibroblast growth factor regulates human neuroectoderm specification through ERK1/2-PARP-1 pathway
    • Yoo, Y. D., Huang, C. T., Zhang, X., Lavaute, T. M. and Zhang, S.-C. (2011). Fibroblast growth factor regulates human neuroectoderm specification through ERK1/2-PARP-1 pathway. Stem Cells 29, 1975-1982.
    • (2011) Stem Cells , vol.29 , pp. 1975-1982
    • Yoo, Y.D.1    Huang, C.T.2    Zhang, X.3    Lavaute, T.M.4    Zhang, S.-C.5
  • 238
    • 26944463126 scopus 로고    scopus 로고
    • Phosphatidylserine-dependent engulfment by macrophages of nuclei from erythroid precursor cells
    • Yoshida, H., Kawane, K., Koike, M., Mori, Y., Uchiyama, Y. and Nagata, S. (2005). Phosphatidylserine-dependent engulfment by macrophages of nuclei from erythroid precursor cells. Nature 437, 754-758.
    • (2005) Nature , vol.437 , pp. 754-758
    • Yoshida, H.1    Kawane, K.2    Koike, M.3    Mori, Y.4    Uchiyama, Y.5    Nagata, S.6
  • 239
    • 27744542002 scopus 로고    scopus 로고
    • Regulation of ocular lens development by Smad-interacting protein 1 involving Foxe3 activation
    • Yoshimoto, A., Saigou, Y., Higashi, Y. and Kondoh, H. (2005). Regulation of ocular lens development by Smad-interacting protein 1 involving Foxe3 activation. Development 132, 4437-4448.
    • (2005) Development , vol.132 , pp. 4437-4448
    • Yoshimoto, A.1    Saigou, Y.2    Higashi, Y.3    Kondoh, H.4
  • 241
    • 33846931622 scopus 로고    scopus 로고
    • Proteolytic mechanisms underlying mitochondrial degradation in the ocular lens
    • Zandy, A. J. and Bassnett, S. (2007). Proteolytic mechanisms underlying mitochondrial degradation in the ocular lens. Invest. Ophthalmol. Vis. Sci. 48, 293-302.
    • (2007) Invest. Ophthalmol. Vis. Sci. , vol.48 , pp. 293-302
    • Zandy, A.J.1    Bassnett, S.2
  • 242
  • 243
    • 0032532490 scopus 로고    scopus 로고
    • Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development
    • Zhang, P., Wong, C., DePinho, R. A., Harper, J. W. and Elledge, S. J. (1998). Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development. Genes Dev. 12, 3162-3167.
    • (1998) Genes Dev. , vol.12 , pp. 3162-3167
    • Zhang, P.1    Wong, C.2    DePinho, R.A.3    Harper, J.W.4    Elledge, S.J.5
  • 244
    • 0037102552 scopus 로고    scopus 로고
    • Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis
    • Zhang, X., Friedman, A., Heaney, S., Purcell, P. and Maas, R. L. (2002). Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis. Genes Dev. 16, 2097-2107.
    • (2002) Genes Dev. , vol.16 , pp. 2097-2107
    • Zhang, X.1    Friedman, A.2    Heaney, S.3    Purcell, P.4    Maas, R.L.5
  • 246
    • 77951837150 scopus 로고    scopus 로고
    • The Hippo-YAP pathway in organ size control and tumorigenesis: An updated version
    • Zhao, B., Li, L., Lei, Q. and Guan, K. L. (2010). The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version. Genes Dev. 24, 862-874.
    • (2010) Genes Dev. , vol.24 , pp. 862-874
    • Zhao, B.1    Li, L.2    Lei, Q.3    Guan, K.L.4
  • 247
    • 84861601544 scopus 로고    scopus 로고
    • Loss of Msx2 function down-regulates the FoxE3 expression and results in anterior segment dysgenesis resembling Peters anomaly
    • Zhao, J., Kawai, K.,Wang, H., Wu, D.,Wang, M., Yue, Z., Zhang, J. and Liu, Y.-H. (2012). Loss of Msx2 function down-regulates the FoxE3 expression and results in anterior segment dysgenesis resembling Peters anomaly. Am. J. Pathol. 180, 2230-2239.
    • (2012) Am. J. Pathol. , vol.180 , pp. 2230-2239
    • Zhao, J.1    Kawai, K.2    Wang, H.3    Wu, D.4    Wang, M.5    Yue, Z.6    Zhang, J.7    Liu, Y.-H.8
  • 248
    • 33746734402 scopus 로고    scopus 로고
    • A hierarchy of proliferative cells exists in mouse lens epithelium: Implications for lens maintenance
    • Zhou, M., Leiberman, J., Xu, J. and Lavker, R. M. (2006). A hierarchy of proliferative cells exists in mouse lens epithelium: implications for lens maintenance. Invest. Ophthalmol. Vis. Sci. 47, 2997-3003.
    • (2006) Invest. Ophthalmol. Vis. Sci. , vol.47 , pp. 2997-3003
    • Zhou, M.1    Leiberman, J.2    Xu, J.3    Lavker, R.M.4


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