메뉴 건너뛰기




Volumn 9, Issue 4, 2013, Pages

The Histone Demethylase Jarid1b Ensures Faithful Mouse Development by Protecting Developmental Genes from Aberrant H3K4me3

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEMETHYLASE; HISTONE H3; LYSINE; POLYCOMB GROUP PROTEIN; PROTEIN JARID1B; UNCLASSIFIED DRUG; HISTONE; NUCLEAR PROTEIN; REPRESSOR PROTEIN;

EID: 84876876558     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003461     Document Type: Article
Times cited : (102)

References (68)
  • 1
    • 34249026300 scopus 로고    scopus 로고
    • High-Resolution Profiling of Histone Methylations in the Human Genome
    • Barski A, Cuddapah S, Cui K, Roh T-Y, Schones DE, et al. (2007) High-Resolution Profiling of Histone Methylations in the Human Genome. Cell 129: 823-837.
    • (2007) Cell , vol.129 , pp. 823-837
    • Barski, A.1    Cuddapah, S.2    Cui, K.3    Roh, T.-Y.4    Schones, D.E.5
  • 2
    • 2642570305 scopus 로고    scopus 로고
    • The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote
    • Schübeler D, MacAlpine DM, Scalzo D, Wirbelauer C, Kooperberg C, et al. (2004) The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote. Genes & Development 18: 1263-1271.
    • (2004) Genes & Development , vol.18 , pp. 1263-1271
    • Schübeler, D.1    MacAlpine, D.M.2    Scalzo, D.3    Wirbelauer, C.4    Kooperberg, C.5
  • 3
    • 34447098370 scopus 로고    scopus 로고
    • A chromatin landmark and transcription initiation at most promoters in human cells
    • Guenther MG, Levine SS, Boyer LA, Jaenisch R, Young RA, (2007) A chromatin landmark and transcription initiation at most promoters in human cells. Cell 130: 77-88.
    • (2007) Cell , vol.130 , pp. 77-88
    • Guenther, M.G.1    Levine, S.S.2    Boyer, L.A.3    Jaenisch, R.4    Young, R.A.5
  • 4
    • 70349335528 scopus 로고    scopus 로고
    • Mechanisms of transcriptional repression by histone lysine methylation
    • Hublitz P, Albert M, Peters AHFM, (2009) Mechanisms of transcriptional repression by histone lysine methylation. Int J Dev Biol 53: 335-354.
    • (2009) Int J Dev Biol , vol.53 , pp. 335-354
    • Hublitz, P.1    Albert, M.2    Peters, A.H.F.M.3
  • 5
    • 0028869112 scopus 로고
    • Altered Hox expression and segmental identity in Mll-mutant mice
    • Yu BD, Hess JL, Horning SE, Brown GA, Korsmeyer SJ, (1995) Altered Hox expression and segmental identity in Mll-mutant mice. Nature 378: 505-508.
    • (1995) Nature , vol.378 , pp. 505-508
    • Yu, B.D.1    Hess, J.L.2    Horning, S.E.3    Brown, G.A.4    Korsmeyer, S.J.5
  • 6
    • 33646681035 scopus 로고    scopus 로고
    • Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development
    • Glaser S, Schaft J, Lubitz S, Vintersten K, van der Hoeven F, et al. (2006) Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development. Development 133: 1423-1432.
    • (2006) Development , vol.133 , pp. 1423-1432
    • Glaser, S.1    Schaft, J.2    Lubitz, S.3    Vintersten, K.4    van der Hoeven, F.5
  • 7
    • 0032126677 scopus 로고    scopus 로고
    • Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice
    • Yagi H, Deguchi K, Aono A, Tani Y, Kishimoto T, et al. (1998) Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice. Blood 92: 108-117.
    • (1998) Blood , vol.92 , pp. 108-117
    • Yagi, H.1    Deguchi, K.2    Aono, A.3    Tani, Y.4    Kishimoto, T.5
  • 8
    • 1642281239 scopus 로고    scopus 로고
    • Definitive hematopoiesis requires the mixed-lineage leukemia gene
    • Ernst P, Fisher JK, Avery W, Wade S, Foy D, et al. (2004) Definitive hematopoiesis requires the mixed-lineage leukemia gene. Developmental Cell 6: 437-443.
    • (2004) Developmental Cell , vol.6 , pp. 437-443
    • Ernst, P.1    Fisher, J.K.2    Avery, W.3    Wade, S.4    Foy, D.5
  • 9
    • 63649125648 scopus 로고    scopus 로고
    • Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells
    • Lim DA, Huang Y-C, Swigut T, Mirick AL, Garcia-Verdugo JM, et al. (2009) Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells. Nature 458: 529-533.
    • (2009) Nature , vol.458 , pp. 529-533
    • Lim, D.A.1    Huang, Y.-C.2    Swigut, T.3    Mirick, A.L.4    Garcia-Verdugo, J.M.5
  • 10
    • 33646070846 scopus 로고    scopus 로고
    • A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells
    • Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, et al. (2006) A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells. Cell 125: 315-326.
    • (2006) Cell , vol.125 , pp. 315-326
    • Bernstein, B.E.1    Mikkelsen, T.S.2    Xie, X.3    Kamal, M.4    Huebert, D.J.5
  • 11
    • 41749108163 scopus 로고    scopus 로고
    • Stem cell regulation by polycomb repressors: postponing commitment
    • Pietersen AM, van Lohuizen M, (2008) Stem cell regulation by polycomb repressors: postponing commitment. Current Opinion in Cell Biology 20: 201-207.
    • (2008) Current Opinion in Cell Biology , vol.20 , pp. 201-207
    • Pietersen, A.M.1    van Lohuizen, M.2
  • 12
    • 78751662908 scopus 로고    scopus 로고
    • The Polycomb complex PRC2 and its mark in life
    • Margueron R, Reinberg D, (2011) The Polycomb complex PRC2 and its mark in life. Nature 469: 343-349.
    • (2011) Nature , vol.469 , pp. 343-349
    • Margueron, R.1    Reinberg, D.2
  • 13
    • 0036830642 scopus 로고    scopus 로고
    • Role of histone H3 lysine 27 methylation in Polycomb-group silencing
    • Cao R, Wang L, Wang H, Xia L, Erdjument-Bromage H, et al. (2002) Role of histone H3 lysine 27 methylation in Polycomb-group silencing. Science 298: 1039-1043.
    • (2002) Science , vol.298 , pp. 1039-1043
    • Cao, R.1    Wang, L.2    Wang, H.3    Xia, L.4    Erdjument-Bromage, H.5
  • 14
    • 29144487990 scopus 로고    scopus 로고
    • Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing
    • Cao R, Tsukada Y-I, Zhang Y, (2005) Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. Molecular Cell 20: 845-854.
    • (2005) Molecular Cell , vol.20 , pp. 845-854
    • Cao, R.1    Tsukada, Y.-I.2    Zhang, Y.3
  • 15
    • 2942574510 scopus 로고    scopus 로고
    • Hierarchical recruitment of polycomb group silencing complexes
    • Wang L, Brown JL, Cao R, Zhang Y, Kassis JA, et al. (2004) Hierarchical recruitment of polycomb group silencing complexes. Molecular Cell 14: 637-646.
    • (2004) Molecular Cell , vol.14 , pp. 637-646
    • Wang, L.1    Brown, J.L.2    Cao, R.3    Zhang, Y.4    Kassis, J.A.5
  • 16
    • 33746407708 scopus 로고    scopus 로고
    • Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing
    • Schoeftner S, Sengupta AK, Kubicek S, Mechtler K, Spahn L, et al. (2006) Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing. The EMBO Journal 25: 3110-3122.
    • (2006) The EMBO Journal , vol.25 , pp. 3110-3122
    • Schoeftner, S.1    Sengupta, A.K.2    Kubicek, S.3    Mechtler, K.4    Spahn, L.5
  • 17
    • 40849129243 scopus 로고    scopus 로고
    • PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos
    • Puschendorf M, Terranova R, Boutsma E, Mao X, Isono K-I, et al. (2008) PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos. Nat Genet 40: 411-420.
    • (2008) Nat Genet , vol.40 , pp. 411-420
    • Puschendorf, M.1    Terranova, R.2    Boutsma, E.3    Mao, X.4    Isono, K.-I.5
  • 18
    • 84857367297 scopus 로고    scopus 로고
    • RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3
    • Tavares L, Dimitrova E, Oxley D, Webster J, Poot R, et al. (2012) RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3. Cell 148: 664-678.
    • (2012) Cell , vol.148 , pp. 664-678
    • Tavares, L.1    Dimitrova, E.2    Oxley, D.3    Webster, J.4    Poot, R.5
  • 19
    • 11144332565 scopus 로고    scopus 로고
    • Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
    • Shi Y, Lan F, Matson C, Mulligan P, Whetstine JR, et al. (2004) Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 119: 941-953.
    • (2004) Cell , vol.119 , pp. 941-953
    • Shi, Y.1    Lan, F.2    Matson, C.3    Mulligan, P.4    Whetstine, J.R.5
  • 20
    • 84860215207 scopus 로고    scopus 로고
    • Molecular mechanisms and potential functions of histone demethylases
    • Kooistra SM, Helin K, (2012) Molecular mechanisms and potential functions of histone demethylases. Nat Rev Mol Cell Biol 13: 297-311.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 297-311
    • Kooistra, S.M.1    Helin, K.2
  • 21
    • 0033786540 scopus 로고    scopus 로고
    • A screen for new trithorax group genes identified little imaginal discs, the Drosophila melanogaster homologue of human retinoblastoma binding protein 2
    • Gildea JJ, Lopez R, Shearn A, (2000) A screen for new trithorax group genes identified little imaginal discs, the Drosophila melanogaster homologue of human retinoblastoma binding protein 2. Genetics 156: 645-663.
    • (2000) Genetics , vol.156 , pp. 645-663
    • Gildea, J.J.1    Lopez, R.2    Shearn, A.3
  • 22
    • 81555214034 scopus 로고    scopus 로고
    • Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans
    • Greer EL, Maures TJ, Ucar D, Hauswirth AG, Mancini E, et al. (2011) Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans. Nature 479: 365-371.
    • (2011) Nature , vol.479 , pp. 365-371
    • Greer, E.L.1    Maures, T.J.2    Ucar, D.3    Hauswirth, A.G.4    Mancini, E.5
  • 23
    • 33947245128 scopus 로고    scopus 로고
    • RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3
    • Christensen J, Agger K, Cloos PAC, Pasini D, Rose S, et al. (2007) RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3. Cell 128: 1063-1076.
    • (2007) Cell , vol.128 , pp. 1063-1076
    • Christensen, J.1    Agger, K.2    Cloos, P.A.C.3    Pasini, D.4    Rose, S.5
  • 24
    • 33847401344 scopus 로고    scopus 로고
    • The retinoblastoma binding protein RBP2 is an H3K4 demethylase
    • Klose RJ, Yan Q, Tothova Z, Yamane K, Erdjument-Bromage H, et al. (2007) The retinoblastoma binding protein RBP2 is an H3K4 demethylase. Cell 128: 889-900.
    • (2007) Cell , vol.128 , pp. 889-900
    • Klose, R.J.1    Yan, Q.2    Tothova, Z.3    Yamane, K.4    Erdjument-Bromage, H.5
  • 25
    • 79955019522 scopus 로고    scopus 로고
    • PLU-1/JARID1B/KDM5B is required for embryonic survival and contributes to cell proliferation in the mammary gland and in ER+ breast cancer cells
    • Catchpole S, Spencer-Dene B, Hall D, Santangelo S, Rosewell I, et al. (2011) PLU-1/JARID1B/KDM5B is required for embryonic survival and contributes to cell proliferation in the mammary gland and in ER+ breast cancer cells. Int J Oncol 38: 1267-1277.
    • (2011) Int J Oncol , vol.38 , pp. 1267-1277
    • Catchpole, S.1    Spencer-Dene, B.2    Hall, D.3    Santangelo, S.4    Rosewell, I.5
  • 26
    • 79953708822 scopus 로고    scopus 로고
    • Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer
    • Blair LP, Cao J, Zou MR, Sayegh J, Yan Q, (2011) Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer. Cancers 3: 1383-1404.
    • (2011) Cancers , vol.3 , pp. 1383-1404
    • Blair, L.P.1    Cao, J.2    Zou, M.R.3    Sayegh, J.4    Yan, Q.5
  • 27
    • 49349092791 scopus 로고    scopus 로고
    • The Histone Demethylase KDM5b/JARID1b Plays a Role in Cell Fate Decisions by Blocking Terminal Differentiation
    • Dey BK, Stalker L, Schnerch A, Bhatia M, Taylor-Papidimitriou J, et al. (2008) The Histone Demethylase KDM5b/JARID1b Plays a Role in Cell Fate Decisions by Blocking Terminal Differentiation. Molecular and Cellular Biology 28: 5312-5327.
    • (2008) Molecular and Cellular Biology , vol.28 , pp. 5312-5327
    • Dey, B.K.1    Stalker, L.2    Schnerch, A.3    Bhatia, M.4    Taylor-Papidimitriou, J.5
  • 28
    • 81255160602 scopus 로고    scopus 로고
    • Jarid1b targets genes regulating development and is involved in neural differentiation
    • Schmitz SU, Albert M, Malatesta M, Morey L, Johansen JV, et al. (2011) Jarid1b targets genes regulating development and is involved in neural differentiation. The EMBO Journal 30: 4586-4600.
    • (2011) The EMBO Journal , vol.30 , pp. 4586-4600
    • Schmitz, S.U.1    Albert, M.2    Malatesta, M.3    Morey, L.4    Johansen, J.V.5
  • 29
    • 0242468568 scopus 로고    scopus 로고
    • PLU-1, a transcriptional repressor and putative testis-cancer antigen, has a specific expression and localisation pattern during meiosis
    • Madsen B, Tarsounas M, Burchell JM, Hall D, Poulsom R, et al. (2003) PLU-1, a transcriptional repressor and putative testis-cancer antigen, has a specific expression and localisation pattern during meiosis. Chromosoma 112: 124-132.
    • (2003) Chromosoma , vol.112 , pp. 124-132
    • Madsen, B.1    Tarsounas, M.2    Burchell, J.M.3    Hall, D.4    Poulsom, R.5
  • 30
    • 58249115047 scopus 로고    scopus 로고
    • Interpreting Neonatal Lethal Phenotypes in Mouse Mutants: Insights Into Gene Function and Human Diseases
    • Turgeon B, Meloche S, (2009) Interpreting Neonatal Lethal Phenotypes in Mouse Mutants: Insights Into Gene Function and Human Diseases. Physiological Reviews 89: 1-26.
    • (2009) Physiological Reviews , vol.89 , pp. 1-26
    • Turgeon, B.1    Meloche, S.2
  • 31
    • 0037687290 scopus 로고    scopus 로고
    • The Na,K-ATPase alpha 2 isoform is expressed in neurons, and its absence disrupts neuronal activity in newborn mice
    • Moseley AE, Lieske SP, Wetzel RK, James PF, He S, et al. (2003) The Na,K-ATPase alpha 2 isoform is expressed in neurons, and its absence disrupts neuronal activity in newborn mice. J Biol Chem 278: 5317-5324.
    • (2003) J Biol Chem , vol.278 , pp. 5317-5324
    • Moseley, A.E.1    Lieske, S.P.2    Wetzel, R.K.3    James, P.F.4    He, S.5
  • 32
    • 0037180829 scopus 로고    scopus 로고
    • Hydrophobic surfactant proteins in lung function and disease
    • Whitsett JA, Weaver TE, (2002) Hydrophobic surfactant proteins in lung function and disease. N Engl J Med 347: 2141-2148.
    • (2002) N Engl J Med , vol.347 , pp. 2141-2148
    • Whitsett, J.A.1    Weaver, T.E.2
  • 33
    • 70349756959 scopus 로고    scopus 로고
    • Loss of Erk3 function in mice leads to intrauterine growth restriction, pulmonary immaturity, and neonatal lethality
    • Klinger S, Turgeon B, Lévesque K, Wood GA, Aagaard-Tillery KM, et al. (2009) Loss of Erk3 function in mice leads to intrauterine growth restriction, pulmonary immaturity, and neonatal lethality. Proc Natl Acad Sci USA 106: 16710-16715.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 16710-16715
    • Klinger, S.1    Turgeon, B.2    Lévesque, K.3    Wood, G.A.4    Aagaard-Tillery, K.M.5
  • 35
    • 10744221393 scopus 로고    scopus 로고
    • Inactivation of the glycine transporter 1 gene discloses vital role of glial glycine uptake in glycinergic inhibition
    • Gomeza J, Hülsmann S, Ohno K, Eulenburg V, Szöke K, et al. (2003) Inactivation of the glycine transporter 1 gene discloses vital role of glial glycine uptake in glycinergic inhibition. Neuron 40: 785-796.
    • (2003) Neuron , vol.40 , pp. 785-796
    • Gomeza, J.1    Hülsmann, S.2    Ohno, K.3    Eulenburg, V.4    Szöke, K.5
  • 36
    • 35548945282 scopus 로고    scopus 로고
    • Patterning and axon guidance of cranial motor neurons
    • Guthrie S, (2007) Patterning and axon guidance of cranial motor neurons. Nat Rev Neurosci 8: 859-871.
    • (2007) Nat Rev Neurosci , vol.8 , pp. 859-871
    • Guthrie, S.1
  • 37
    • 0035461440 scopus 로고    scopus 로고
    • Molecular genetics of cranial nerve development in mouse
    • Cordes SP, (2001) Molecular genetics of cranial nerve development in mouse. Nat Rev Neurosci 2: 611-623.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 611-623
    • Cordes, S.P.1
  • 38
    • 10644226726 scopus 로고    scopus 로고
    • Characterisation and developmental expression of mouse Plu-1, a homologue of a human nuclear protein (PLU-1) which is specifically up-regulated in breast cancer
    • Madsen B, Spencer-Dene B, Poulsom R, Hall D, Lu PJ, et al. (2002) Characterisation and developmental expression of mouse Plu-1, a homologue of a human nuclear protein (PLU-1) which is specifically up-regulated in breast cancer. Mech Dev 119 (Suppl 1): S239-S246.
    • (2002) Mech Dev , vol.119 , Issue.SUPPL. 1
    • Madsen, B.1    Spencer-Dene, B.2    Poulsom, R.3    Hall, D.4    Lu, P.J.5
  • 39
    • 0029891279 scopus 로고    scopus 로고
    • A role for mel-18, a Polycomb group-related vertebrate gene, during theanteroposterior specification of the axial skeleton
    • Akasaka T, Kanno M, Balling R, Mieza MA, Taniguchi M, et al. (1996) A role for mel-18, a Polycomb group-related vertebrate gene, during theanteroposterior specification of the axial skeleton. Development 122: 1513-1522.
    • (1996) Development , vol.122 , pp. 1513-1522
    • Akasaka, T.1    Kanno, M.2    Balling, R.3    Mieza, M.A.4    Taniguchi, M.5
  • 41
    • 0035184055 scopus 로고    scopus 로고
    • Early eye development in vertebrates
    • Chow RL, Lang RA, (2001) Early eye development in vertebrates. Annu Rev Cell Dev Biol 17: 255-296.
    • (2001) Annu Rev Cell Dev Biol , vol.17 , pp. 255-296
    • Chow, R.L.1    Lang, R.A.2
  • 42
    • 70350217448 scopus 로고    scopus 로고
    • HoxGenes and Segmentation of the Hindbrain and Axial Skeleton
    • Alexander T, Nolte C, Krumlauf R, (2009) HoxGenes and Segmentation of the Hindbrain and Axial Skeleton. Annu Rev Cell Dev Biol 25: 431-456.
    • (2009) Annu Rev Cell Dev Biol , vol.25 , pp. 431-456
    • Alexander, T.1    Nolte, C.2    Krumlauf, R.3
  • 43
    • 33947244845 scopus 로고    scopus 로고
    • PLU-1 Is an H3K4 Demethylase Involved in Transcriptional Repression and Breast Cancer Cell Proliferation
    • Yamane K, Tateishi K, Klose RJ, Fang J, Fabrizio LA, et al. (2007) PLU-1 Is an H3K4 Demethylase Involved in Transcriptional Repression and Breast Cancer Cell Proliferation. Molecular Cell 25: 801-812.
    • (2007) Molecular Cell , vol.25 , pp. 801-812
    • Yamane, K.1    Tateishi, K.2    Klose, R.J.3    Fang, J.4    Fabrizio, L.A.5
  • 44
    • 67651208830 scopus 로고    scopus 로고
    • The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis
    • doi:10.1371/journal.pgen.1000511
    • Sansom SN, Griffiths DS, Faedo A, Kleinjan D-J, Ruan Y, et al. (2009) The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. PLoS Genet 5: e1000511 doi:10.1371/journal.pgen.1000511.
    • (2009) PLoS Genet , vol.5
    • Sansom, S.N.1    Griffiths, D.S.2    Faedo, A.3    Kleinjan, D.-J.4    Ruan, Y.5
  • 45
    • 84860572048 scopus 로고    scopus 로고
    • Transcriptional regulation of rod photoreceptor homeostasis revealed by in vivo NRL targetome analysis
    • doi:10.1371/journal.pgen.1002649
    • Hao H, Kim DS, Klocke B, Johnson KR, Cui K, et al. (2012) Transcriptional regulation of rod photoreceptor homeostasis revealed by in vivo NRL targetome analysis. PLoS Genet 8: e1002649 doi:10.1371/journal.pgen.1002649.
    • (2012) PLoS Genet , vol.8
    • Hao, H.1    Kim, D.S.2    Klocke, B.3    Johnson, K.R.4    Cui, K.5
  • 46
    • 19944430270 scopus 로고    scopus 로고
    • Mutations in the JARID1C Gene, Which Is Involved in Transcriptional Regulation and Chromatin Remodeling, Cause X-Linked Mental Retardation
    • Jensen LR, Amende M, Gurok U, Moser B, Gimmel V, et al. (2005) Mutations in the JARID1C Gene, Which Is Involved in Transcriptional Regulation and Chromatin Remodeling, Cause X-Linked Mental Retardation. The American Journal of Human Genetics 76: 227-236.
    • (2005) The American Journal of Human Genetics , vol.76 , pp. 227-236
    • Jensen, L.R.1    Amende, M.2    Gurok, U.3    Moser, B.4    Gimmel, V.5
  • 48
    • 79951711112 scopus 로고    scopus 로고
    • Role for Dpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains
    • Jiang H, Shukla A, Wang X, Chen W-Y, Bernstein BE, et al. (2011) Role for Dpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains. Cell 144: 513-525.
    • (2011) Cell , vol.144 , pp. 513-525
    • Jiang, H.1    Shukla, A.2    Wang, X.3    Chen, W.-Y.4    Bernstein, B.E.5
  • 49
    • 79960271413 scopus 로고    scopus 로고
    • Can a Systems Perspective Help Us Appreciate the Biological Meaning of Small Effects?
    • El-Samad H, Madhani HD, (2011) Can a Systems Perspective Help Us Appreciate the Biological Meaning of Small Effects? Developmental Cell 21: 11-13.
    • (2011) Developmental Cell , vol.21 , pp. 11-13
    • El-Samad, H.1    Madhani, H.D.2
  • 50
    • 33646760234 scopus 로고    scopus 로고
    • Developmental malformations of the eye: the role of PAX6, SOX2 and OTX2
    • Hever AM, Williamson KA, van Heyningen V, (2006) Developmental malformations of the eye: the role of PAX6, SOX2 and OTX2. Clin Genet 69: 459-470.
    • (2006) Clin Genet , vol.69 , pp. 459-470
    • Hever, A.M.1    Williamson, K.A.2    van Heyningen, V.3
  • 51
    • 55049119613 scopus 로고    scopus 로고
    • Concise review: Pax6 transcription factor contributes to both embryonic and adult neurogenesis as a multifunctional regulator
    • Osumi N, Shinohara H, Numayama-Tsuruta K, Maekawa M, (2008) Concise review: Pax6 transcription factor contributes to both embryonic and adult neurogenesis as a multifunctional regulator. Stem Cells 26: 1663-1672.
    • (2008) Stem Cells , vol.26 , pp. 1663-1672
    • Osumi, N.1    Shinohara, H.2    Numayama-Tsuruta, K.3    Maekawa, M.4
  • 52
    • 0030581164 scopus 로고    scopus 로고
    • Influence of PAX6 gene dosage on development: overexpression causes severe eye abnormalities
    • Schedl A, Ross A, Lee M, Engelkamp D, Rashbass P, et al. (1996) Influence of PAX6 gene dosage on development: overexpression causes severe eye abnormalities. Cell 86: 71-82.
    • (1996) Cell , vol.86 , pp. 71-82
    • Schedl, A.1    Ross, A.2    Lee, M.3    Engelkamp, D.4    Rashbass, P.5
  • 53
    • 84860470958 scopus 로고    scopus 로고
    • Aberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cells
    • doi:10.1371/journal.pone.0036211
    • Wortham M, Jin G, Sun JL, Bigner DD, He Y, et al. (2012) Aberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cells. PLoS ONE 7: e36211 doi:10.1371/journal.pone.0036211.
    • (2012) PLoS ONE , vol.7
    • Wortham, M.1    Jin, G.2    Sun, J.L.3    Bigner, D.D.4    He, Y.5
  • 54
    • 84868129311 scopus 로고    scopus 로고
    • dKDM5/LID regulates H3K4me3 dynamics at the transcription-start site (TSS) of actively transcribed developmental genes
    • Lloret-Llinares M, Pérez-Lluch S, Rossell D, Morán T, Ponsa-Cobas J, et al. (2012) dKDM5/LID regulates H3K4me3 dynamics at the transcription-start site (TSS) of actively transcribed developmental genes. Nucleic Acids Res.
    • (2012) Nucleic Acids Res
    • Lloret-Llinares, M.1    Pérez-Lluch, S.2    Rossell, D.3    Morán, T.4    Ponsa-Cobas, J.5
  • 55
    • 79951855952 scopus 로고    scopus 로고
    • Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly
    • Fukuda T, Tokunaga A, Sakamoto R, Yoshida N, (2011) Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly. Molecular and Cellular Neuroscience 46: 614-624.
    • (2011) Molecular and Cellular Neuroscience , vol.46 , pp. 614-624
    • Fukuda, T.1    Tokunaga, A.2    Sakamoto, R.3    Yoshida, N.4
  • 56
    • 77955649698 scopus 로고    scopus 로고
    • An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure
    • Harris MJ, Juriloff DM, (2010) An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure. Birth Defects Research Part A: Clinical and Molecular Teratology 88: 653-669.
    • (2010) Birth Defects Research Part A: Clinical and Molecular Teratology , vol.88 , pp. 653-669
    • Harris, M.J.1    Juriloff, D.M.2
  • 57
    • 83055180178 scopus 로고    scopus 로고
    • Predicting mutation outcome from early stochastic variation in genetic interaction partners
    • Burga A, Casanueva MO, Lehner B, (2011) Predicting mutation outcome from early stochastic variation in genetic interaction partners. Nature 480: 250-253.
    • (2011) Nature , vol.480 , pp. 250-253
    • Burga, A.1    Casanueva, M.O.2    Lehner, B.3
  • 58
    • 77249114260 scopus 로고    scopus 로고
    • Variability in gene expression underlies incomplete penetrance
    • Raj A, Rifkin SA, Andersen E, van Oudenaarden A, (2010) Variability in gene expression underlies incomplete penetrance. Nature 463: 913-918.
    • (2010) Nature , vol.463 , pp. 913-918
    • Raj, A.1    Rifkin, S.A.2    Andersen, E.3    van Oudenaarden, A.4
  • 59
    • 79961172475 scopus 로고    scopus 로고
    • A Polycomb-based switch underlying quantitative epigenetic memory
    • Angel A, Song J, Dean C, Howard M, (2011) A Polycomb-based switch underlying quantitative epigenetic memory. Nature 476: 105-108.
    • (2011) Nature , vol.476 , pp. 105-108
    • Angel, A.1    Song, J.2    Dean, C.3    Howard, M.4
  • 61
    • 0029566108 scopus 로고
    • A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells
    • Schwenk F, Baron U, Rajewsky K, (1995) A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells. Nucleic Acids Res 23: 5080-5081.
    • (1995) Nucleic Acids Res , vol.23 , pp. 5080-5081
    • Schwenk, F.1    Baron, U.2    Rajewsky, K.3
  • 62
    • 79954468738 scopus 로고    scopus 로고
    • Hox and Pbx Factors Control Retinoic Acid Synthesis during Hindbrain Segmentation
    • Vitobello A, Ferretti E, Lampe X, Vilain N, Ducret S, et al. (2011) Hox and Pbx Factors Control Retinoic Acid Synthesis during Hindbrain Segmentation. Developmental Cell 20: 469-482.
    • (2011) Developmental Cell , vol.20 , pp. 469-482
    • Vitobello, A.1    Ferretti, E.2    Lampe, X.3    Vilain, N.4    Ducret, S.5
  • 63
    • 34547126890 scopus 로고    scopus 로고
    • Optimized flow cytometric analysis of central nervous system tissue reveals novel functional relationships among cells expressing CD133, CD15, and CD24
    • Panchision DM, Chen H-L, Pistollato F, Papini D, Ni H-T, et al. (2007) Optimized flow cytometric analysis of central nervous system tissue reveals novel functional relationships among cells expressing CD133, CD15, and CD24. Stem Cells 25: 1560-1570.
    • (2007) Stem Cells , vol.25 , pp. 1560-1570
    • Panchision, D.M.1    Chen, H.-L.2    Pistollato, F.3    Papini, D.4    Ni, H.-T.5
  • 65
    • 62349130698 scopus 로고    scopus 로고
    • Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
    • Langmead B, Trapnell C, Pop M, Salzberg SL, (2009) Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol 10: R25.
    • (2009) Genome Biol , vol.10
    • Langmead, B.1    Trapnell, C.2    Pop, M.3    Salzberg, S.L.4
  • 67
    • 77951770756 scopus 로고    scopus 로고
    • BEDTools: a flexible suite of utilities for comparing genomic features
    • Quinlan AR, Hall IM, (2010) BEDTools: a flexible suite of utilities for comparing genomic features. Bioinformatics 26: 841-842.
    • (2010) Bioinformatics , vol.26 , pp. 841-842
    • Quinlan, A.R.1    Hall, I.M.2
  • 68
    • 84859350055 scopus 로고    scopus 로고
    • Gene Array Analyzer: alternative usage of gene arrays to study alternative splicing events
    • Gellert P, Teranishi M, Jenniches K, De Gaspari P, John D, et al. (2012) Gene Array Analyzer: alternative usage of gene arrays to study alternative splicing events. Nucleic Acids Res 40: 2414-2425.
    • (2012) Nucleic Acids Res , vol.40 , pp. 2414-2425
    • Gellert, P.1    Teranishi, M.2    Jenniches, K.3    de Gaspari, P.4    John, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.