Lens fiber cell differentiation and denucleation are disrupted through expression of the N-terminal nuclear receptor box of Ncoa6 and result in p53-dependent and p53-independent apoptosis

Molecular Biology of the Cell

Volumn 21, Issue 14, 2010, Pages 2453-2468

  Wang, Wei Lin ^a   Li, Qingtian ^b   Xu, Jianming ^b   Cvekl, Aleš ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; BIOLOGICAL MARKER; CASPASE 3; CELL NUCLEUS RECEPTOR; GAMMA CRYSTALLIN; HISTONE H2AX; PROTEIN NCOA6; PROTEIN P53; RECEPTOR PROTEIN; TRANSCRIPTION FACTOR C MAF; UNCLASSIFIED DRUG; NCOA6 PROTEIN, MOUSE; NUCLEAR RECEPTOR COACTIVATOR;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CATARACTOGENESIS; CELL COMPARTMENTALIZATION; CELL DIFFERENTIATION; CELL NUCLEUS; CELL SURVIVAL; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVATION; GENE; GENE DELETION; HOMEOSTASIS; LENS FIBER; MITOSIS; MOUSE; NCOA6 GENE; NEWBORN; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; ANIMAL; ANTIBODY SPECIFICITY; BIOLOGICAL MODEL; CATARACT; CHEMISTRY; COMPLICATION; LENS; METABOLISM; MICROPHTHALMIA; PATHOLOGY; STRUCTURE ACTIVITY RELATION;

MUS MUSCULUS;

AMINO ACID MOTIFS; ANIMALS; APOPTOSIS; CASPASE 3; CATARACT; CELL DIFFERENTIATION; ENZYME ACTIVATION; GAMMA-CRYSTALLINS; GENE DELETION; IN SITU NICK-END LABELING; LENS, CRYSTALLINE; MICE; MICE, TRANSGENIC; MICROPHTHALMOS; MODELS, BIOLOGICAL; NUCLEAR RECEPTOR COACTIVATORS; ORGAN SPECIFICITY; PROTO-ONCOGENE PROTEINS C-MAF; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR SUPPRESSOR PROTEIN P53;

EID: 77954626704     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E09-12-1031     Document Type: Article

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