Sumoylation differentially regulates Sp1 to control cell differentiation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 15, 2014, Pages 5574-5579

  Gong, Lili ^a,b   Ji, Wei Ke ^a   Hu, Xiao Hui ^a,c   Hu, Wen Feng ^a,c   Tang, Xiang Cheng ^a,b   Huang, Zhao Xia ^c   Li, Ling ^c   Liu, Mugen ^d   Xiang, Shi Hua ^e   Wu, Erxi ^f   Woodward, Zachary ^a   Liu, Yi Zhi ^b   Nguyen, Quan Dong ^a   Li, David Wan Cheng ^a,b,c  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

^c HUNAN NORMAL UNIVERSITY   (China)

^d BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^e UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^f NORTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

Crystallin Gene Expression; Eye Development; Transcription Regulation

Indexed keywords

BETA CRYSTALLIN; HISTONE ACETYLTRANSFERASE; SUMO 1 PROTEIN; SUMO 2 PROTEIN; SUMO 3 PROTEIN; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3;

ADULT; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL DIFFERENTIATION; CELLULAR DISTRIBUTION; CHROMATIN IMMUNOPRECIPITATION; DNA BINDING; IMMUNOHISTOCHEMISTRY; LENS EPITHELIUM; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN STABILITY; PROTEIN TARGETING; SUMOYLATION; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

CRYSTALLIN GENE EXPRESSION; EYE DEVELOPMENT; TRANSCRIPTION REGULATION;

ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; DNA PRIMERS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; EPITHELIAL CELLS; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LENS, CRYSTALLINE; MICE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SMALL UBIQUITIN-RELATED MODIFIER PROTEINS; SP1 TRANSCRIPTION FACTOR; SUMOYLATION;

EID: 84898774840     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1315034111     Document Type: Article

References (20)

1. Geiss-Friedlander R, Melchior F (2007) Concepts in sumoylation: A decade on. Nat Rev Mol Cell Biol 8(12):947-956
2. Lapenta V, et al. (1997) SMT3A, a human homologue of the S. cerevisiae SMT3 gene, maps to chromosome 21qter and defines a novel gene family. Genomics 40(2): 362-366
3. Kamitani T, Kito K, Nguyen HP, Fukuda-Kamitani T, Yeh ET (1998) Characterization of a second member of the sentrin family of ubiquitin-like proteins. J Biol Chem 273(18): 11349-11353
4. Vertegaal AC, et al. (2006) Distinct and overlapping sets of SUMO-1 and SUMO-2 target proteins revealed by quantitative proteomics. Mol Cell Proteomics 5(12): 2298-2310
5. Alkuraya FS, et al. (2006) SUMO1 haploinsufficiency leads to cleft lip and palate. Science 313(5794):1751
6. Zhang FP, et al. (2008) Sumo-1 function is dispensable in normal mouse development. Mol Cell Biol 28(17):5381-5390
7. Kim KI, Baek SH, Chung CH (2002) Versatile protein tag, SUMO: Its enzymology and biological function. J Cell Physiol 191(3):257-268
8. Jones MC, et al. (2006) Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone. Proc Natl Acad Sci USA 103(44): 16272-16277
9. Deyrieux AF, Rosas-Acosta G, Ozbun MA, Wilson VG (2007) Sumoylation dynamics during keratinocyte differentiation. J Cell Sci 120(Pt 1):125-136
10. La Salle S, Sun F, Zhang XD, Matunis MJ, Handel MA (2008) Developmental control of sumoylation pathway proteins in mouse male germ cells. Dev Biol 321(1):227-237
11. Onishi A, et al. (2009) Pias3-dependent SUMOylation directs rod photoreceptor development. Neuron 61(2):234-246
12. Yan Q, et al. (2010) Sumoylation activates the transcriptional activity of Pax-6, an important transcription factor for eye and brain development. Proc Natl Acad Sci USA 107(49):21034-21039
13. Chamberlain CG, McAvoy JW (1989) Induction of lens fibre differentiation by acidic and basic fibroblast growth factor (FGF). Growth Factors 1(2):125-134
14. McAvoy JW, Chamberlain CG (1989) Fibroblast growth factor (FGF) induces different responses in lens epithelial cells depending on its concentration. Development 107(2): 221-228
15. Suske G (1999) The Sp-family of transcription factors. Gene 238(2):291-300
16. Wang YT, et al. (2008) Sumoylation of specificity protein 1 augments its degradation by changing the localization and increasing the specificity protein 1 proteolytic process. J Mol Biol 380(5):869-885
17. Xu X, Vatsyayan J, Gao C, Bakkenist CJ, Hu J (2010) Sumoylation of eIF4E activates mRNA translation. EMBO Rep 11(4):299-304
18. Billon N, et al. (1999) Cooperation of Sp1 and p300 in the induction of the CDK inhibitor p21WAF1/CIP1 during NGF-mediated neuronal differentiation. Oncogene 18(18):2872-2882
19. Dennig J, Beato M, Suske G (1996) An inhibitor domain in Sp3 regulates its glutaminerich activation domains. EMBO J 15(20):5659-5667
20. Briggs MR, Kadonaga JT, Bell SP, Tjian R (1986) Purification and biochemical characterization of the promoter-specific transcription factor, Sp1. Science 234(4772):47-52.