Prox1 function is crucial for mouse lens-fibre elongation

Nature Genetics

Volumn 21, Issue 3, 1999, Pages 318-322

  Wigle, Jeffrey T ^a   Chowdhury, Kamal ^b   Gruss, Peter ^b   Oliver, Guillermo ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; EMBRYO; GENE CONTROL; GENE EXPRESSION REGULATION; GENE LOCATION; GROWTH REGULATION; HOMEOBOX; LENS; MOUSE; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL;

ANIMALS; BETA-GALACTOSIDASE; BROMODEOXYURIDINE; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CELL DIVISION; CRYSTALLINS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; EMBRYONIC INDUCTION; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; IMMUNOHISTOCHEMISTRY; LENS, CRYSTALLINE; MICE; MICE, MUTANT STRAINS; MICROTUBULE-ASSOCIATED PROTEINS; MUTATION; SACCHAROMYCES CEREVISIAE PROTEINS; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA; MAMMALIA; RODENTIA;

EID: 0033018615     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/6844     Document Type: Article

References (12)

1. Oliver, G. et al. Prox1, a prospero-related homeobox gene expressed during mouse development. Mech. Dev. 44, 3-16 (1993).
2. KiP2 indicates a role in Beckwith-Wiedemann syndrome. Nature 387, 151-158 (1997).
3. KIP2 in the control of tissue growth and development. Genes Dev. 12, 3162-3167 (1998).
4. Nishiguchi, S., Wood, H., Kondoh, H., Lovell-Badge, R. & Episkopou, V. Sox1 directly regulates the γ-crystallin genes and is essential for lens development in mice. Genes Dev. 12, 776-781 (1998).
5. Goring, D.R., Breitman, M.L. & Tsui, L.C. Temporal regulation of six crystallin transcripts during mouse lens development. Exp. Eye Res. 54, 785-795 (1992).
6. Cartier, M., Breitman, M.L. & Tsui, L.C. A frameshift mutation in the γ-E crystallin gene of the Elo mouse. Nature Genet. 2, 42-45 (1992).
7. Sandilands, A. et al. Vimentin and CP49/filensin form distinct networks in the lens which are independently modulated during lens fibre cell differentiation, J. Cell Sci. 108, 1397-1406 (1995).
8. Takeichi, M. The cadherins: cell-cell adhesion molecules controlling animal morphogenesis. Development 102, 639-655 (1988).
9. Lang, R.A. Apoptosis in mammalian eye development: lens morphogenesis, vascular regression and immune privilege. Cell Death Differ. 4, 12-20 (1997).
10. Bober, E., Franz, T., Arnold, H.H., Gruss, P. & Tremblay, P. Pax3 is required for the development of limb muscles: a possible role for the migration of dermomyotomal muscle progenitor cells. Development 120, 603-612 (1994).
11. Kessel, M. & Gruss, P. Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid. Cell 67, 89-104 (1991).
12. Gavrieli, Y., Sherman, Y. & Ben-Sasson, S.A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation J. Cell Biol. 119, 493-501 (1992).