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Volumn 318, Issue 2, 2008, Pages 276-288

Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation

Author keywords

Apoptosis; Cell cycle; Conditional knockout; FGF receptor; Lens development; Lens fiber differentiation; Redundancy

Indexed keywords

ALPHA CRYSTALLIN; BETA CRYSTALLIN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN DEPENDENT KINASE INHIBITOR 1C; FIBROBLAST GROWTH FACTOR RECEPTOR; GAMMA CRYSTALLIN; PAIRED BOX TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR C MAF; TRANSCRIPTION FACTOR PAX6; UVOMORULIN;

EID: 44349136203     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2008.03.028     Document Type: Article
Times cited : (142)

References (63)
  • 1
    • 0032574824 scopus 로고    scopus 로고
    • Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development
    • Arman E., Haffner-Krausz R., Chen Y., Heath J.K., and Lonai P. Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 5082-5087
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 5082-5087
    • Arman, E.1    Haffner-Krausz, R.2    Chen, Y.3    Heath, J.K.4    Lonai, P.5
  • 2
    • 0034312313 scopus 로고    scopus 로고
    • Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye
    • Ashery-Padan R., Marquardt T., Zhou X., and Gruss P. Pax6 activity in the lens primordium is required for lens formation and for correct placement of a single retina in the eye. Genes Dev. 14 (2000) 2701-2711
    • (2000) Genes Dev. , vol.14 , pp. 2701-2711
    • Ashery-Padan, R.1    Marquardt, T.2    Zhou, X.3    Gruss, P.4
  • 3
    • 0036672240 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation
    • Belecky-Adams T.L., Adler R., and Beebe D.C. Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation. Development 129 (2002) 3795-3802
    • (2002) Development , vol.129 , pp. 3795-3802
    • Belecky-Adams, T.L.1    Adler, R.2    Beebe, D.C.3
  • 4
    • 0034650544 scopus 로고    scopus 로고
    • A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle
    • Blixt A., Mahlapuu M., Aitola M., Pelto-Huikko M., Enerback S., and Carlsson P. A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle. Genes Dev. 14 (2000) 245-254
    • (2000) Genes Dev. , vol.14 , pp. 245-254
    • Blixt, A.1    Mahlapuu, M.2    Aitola, M.3    Pelto-Huikko, M.4    Enerback, S.5    Carlsson, P.6
  • 6
    • 0029928791 scopus 로고    scopus 로고
    • Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3
    • Colvin J.S., Bohne B.A., Harding G.W., McEwen D.G., and Ornitz D.M. Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3. Nat. Genet. 12 (1996) 390-397
    • (1996) Nat. Genet. , vol.12 , pp. 390-397
    • Colvin, J.S.1    Bohne, B.A.2    Harding, G.W.3    McEwen, D.G.4    Ornitz, D.M.5
  • 7
    • 0029741796 scopus 로고    scopus 로고
    • FGF receptor-1 (flg) expression is correlated with fibre differentiation during rat lens morphogenesis and growth
    • de Iongh R.U., Lovicu F.J., Hanneken A., Baird A., and McAvoy J.W. FGF receptor-1 (flg) expression is correlated with fibre differentiation during rat lens morphogenesis and growth. Dev. Dyn. 206 (1996) 412-426
    • (1996) Dev. Dyn. , vol.206 , pp. 412-426
    • de Iongh, R.U.1    Lovicu, F.J.2    Hanneken, A.3    Baird, A.4    McAvoy, J.W.5
  • 8
    • 0030764274 scopus 로고    scopus 로고
    • Differential expression of fibroblast growth factor receptors during rat lens morphogenesis and growth
    • de Iongh R.U., Lovicu F.J., Chamberlain C.G., and McAvoy J.W. Differential expression of fibroblast growth factor receptors during rat lens morphogenesis and growth. Invest. Ophthalmol. Vis. Sci. 38 (1997) 1688-1699
    • (1997) Invest. Ophthalmol. Vis. Sci. , vol.38 , pp. 1688-1699
    • de Iongh, R.U.1    Lovicu, F.J.2    Chamberlain, C.G.3    McAvoy, J.W.4
  • 9
    • 0029917507 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 3 is a negative regulator of bone growth
    • Deng C., Wynshaw-Boris A., Zhou F., Kuo A., and Leder P. Fibroblast growth factor receptor 3 is a negative regulator of bone growth. Cell 84 (1996) 911-921
    • (1996) Cell , vol.84 , pp. 911-921
    • Deng, C.1    Wynshaw-Boris, A.2    Zhou, F.3    Kuo, A.4    Leder, P.5
  • 10
    • 0035195501 scopus 로고    scopus 로고
    • The upstream ectoderm enhancer in Pax6 has an important role in lens induction
    • Dimanlig P.V., Faber S.C., Auerbach W., Makarenkova H.P., and Lang R.A. The upstream ectoderm enhancer in Pax6 has an important role in lens induction. Development 128 (2001) 4415-4424
    • (2001) Development , vol.128 , pp. 4415-4424
    • Dimanlig, P.V.1    Faber, S.C.2    Auerbach, W.3    Makarenkova, H.P.4    Lang, R.A.5
  • 11
    • 0242279296 scopus 로고    scopus 로고
    • Lens crystallins
    • Lovicu F.J., and Robinson M.L. (Eds), Cambridge University Press, New York, NY
    • Duncan M.K., Cvekl A., Kantorow M., and Piatigorsky J. Lens crystallins. In: Lovicu F.J., and Robinson M.L. (Eds). Development of the Ocular Lens (2004), Cambridge University Press, New York, NY 119-150
    • (2004) Development of the Ocular Lens , pp. 119-150
    • Duncan, M.K.1    Cvekl, A.2    Kantorow, M.3    Piatigorsky, J.4
  • 14
    • 0036677580 scopus 로고    scopus 로고
    • Bmp signaling is required for development of primary lens fiber cells
    • Faber S.C., Robinson M.L., Makarenkova H.P., and Lang R.A. Bmp signaling is required for development of primary lens fiber cells. Development 129 (2002) 3727-3737
    • (2002) Development , vol.129 , pp. 3727-3737
    • Faber, S.C.1    Robinson, M.L.2    Makarenkova, H.P.3    Lang, R.A.4
  • 15
    • 14844306074 scopus 로고    scopus 로고
    • Lens induction and determination
    • Lovicu F.J., and Robinson M.L. (Eds), Cambridge University Press, New York, NY
    • Fisher M., and Grainger R.M. Lens induction and determination. In: Lovicu F.J., and Robinson M.L. (Eds). Development of the Ocular Lens (2004), Cambridge University Press, New York, NY 27-47
    • (2004) Development of the Ocular Lens , pp. 27-47
    • Fisher, M.1    Grainger, R.M.2
  • 16
    • 0032430772 scopus 로고    scopus 로고
    • BMP4 is essential for lens induction in the mouse embryo
    • Furuta Y., and Hogan B.L. BMP4 is essential for lens induction in the mouse embryo. Genes Dev. 12 (1998) 3764-3775
    • (1998) Genes Dev. , vol.12 , pp. 3764-3775
    • Furuta, Y.1    Hogan, B.L.2
  • 17
    • 19544377184 scopus 로고    scopus 로고
    • Signaling through FGF receptor-2 is required for lens cell survival and for withdrawal from the cell cycle during lens fiber cell differentiation
    • Garcia C.M., Yu K., Zhao H., Ashery-Padan R., Ornitz D.M., Robinson M.L., and Beebe D.C. Signaling through FGF receptor-2 is required for lens cell survival and for withdrawal from the cell cycle during lens fiber cell differentiation. Dev. Dyn. 233 (2005) 516-527
    • (2005) Dev. Dyn. , vol.233 , pp. 516-527
    • Garcia, C.M.1    Yu, K.2    Zhao, H.3    Ashery-Padan, R.4    Ornitz, D.M.5    Robinson, M.L.6    Beebe, D.C.7
  • 19
    • 0037172981 scopus 로고    scopus 로고
    • Mutually regulated expression of Pax6 and Six3 and its implications for the Pax6 haploinsufficient lens phenotype
    • Goudreau G., Petrou P., Reneker L.W., Graw J., Loster J., and Gruss P. Mutually regulated expression of Pax6 and Six3 and its implications for the Pax6 haploinsufficient lens phenotype. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 8719-8724
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 8719-8724
    • Goudreau, G.1    Petrou, P.2    Reneker, L.W.3    Graw, J.4    Loster, J.5    Gruss, P.6
  • 20
    • 0034992107 scopus 로고    scopus 로고
    • Secreted FGFR3, but not FGFR1, inhibits lens fiber differentiation
    • Govindarajan V., and Overbeek P.A. Secreted FGFR3, but not FGFR1, inhibits lens fiber differentiation. Development 128 (2001) 1617-1627
    • (2001) Development , vol.128 , pp. 1617-1627
    • Govindarajan, V.1    Overbeek, P.A.2
  • 21
    • 0037351187 scopus 로고    scopus 로고
    • FGF signaling through FGFR1 is required for olfactory bulb morphogenesis
    • Hebert J.M., Lin M., Partanen J., Rossant J., and McConnell S.K. FGF signaling through FGFR1 is required for olfactory bulb morphogenesis. Development 130 (2003) 1101-1111
    • (2003) Development , vol.130 , pp. 1101-1111
    • Hebert, J.M.1    Lin, M.2    Partanen, J.3    Rossant, J.4    McConnell, S.K.5
  • 22
    • 0037309708 scopus 로고    scopus 로고
    • Evaluation of fibroblast growth factor signaling during lens fiber cell differentiation
    • Huang J.X., Feldmeier M., Shui Y.B., and Beebe D.C. Evaluation of fibroblast growth factor signaling during lens fiber cell differentiation. Invest. Ophthalmol. Vis. Sci. 44 (2003) 680-690
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , pp. 680-690
    • Huang, J.X.1    Feldmeier, M.2    Shui, Y.B.3    Beebe, D.C.4
  • 23
    • 34548136241 scopus 로고    scopus 로고
    • Duration of ERK1/2 phosphorylation induced by FGF or ocular media determines lens cell fate
    • Iyengar L., Wang Q., Rasko J.E., McAvoy J.W., and Lovicu F.J. Duration of ERK1/2 phosphorylation induced by FGF or ocular media determines lens cell fate. Differentiation 75 (2007) 662-668
    • (2007) Differentiation , vol.75 , pp. 662-668
    • Iyengar, L.1    Wang, Q.2    Rasko, J.E.3    McAvoy, J.W.4    Lovicu, F.J.5
  • 25
    • 0033616621 scopus 로고    scopus 로고
    • Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development
    • Kim J.I., Li T., Ho I.C., Grusby M.J., and Glimcher L.H. Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 3781-3785
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 3781-3785
    • Kim, J.I.1    Li, T.2    Ho, I.C.3    Grusby, M.J.4    Glimcher, L.H.5
  • 27
    • 21344452372 scopus 로고    scopus 로고
    • FGF19-FGFR4 signaling elaborates lens induction with the FGF8-L-Maf cascade in the chick embryo
    • Kurose H., Okamoto M., Shimizu M., Bito T., Marcelle C., Noji S., and Ohuchi H. FGF19-FGFR4 signaling elaborates lens induction with the FGF8-L-Maf cascade in the chick embryo. Dev. Growth Differ. 47 (2005) 213-223
    • (2005) Dev. Growth Differ. , vol.47 , pp. 213-223
    • Kurose, H.1    Okamoto, M.2    Shimizu, M.3    Bito, T.4    Marcelle, C.5    Noji, S.6    Ohuchi, H.7
  • 28
    • 11244306331 scopus 로고    scopus 로고
    • Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo
    • Lavine K.J., Yu K., White A.C., Zhang X., Smith C., Partanen J., and Ornitz D.M. Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo. Dev. Cell. 8 (2005) 85-95
    • (2005) Dev. Cell. , vol.8 , pp. 85-95
    • Lavine, K.J.1    Yu, K.2    White, A.C.3    Zhang, X.4    Smith, C.5    Partanen, J.6    Ornitz, D.M.7
  • 29
    • 33745129425 scopus 로고    scopus 로고
    • Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development
    • Lavine K.J., White A.C., Park C., Smith C.S., Choi K., Long F., Hui C.C., and Ornitz D.M. Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development. Genes Dev. 20 (2006) 1651-1666
    • (2006) Genes Dev. , vol.20 , pp. 1651-1666
    • Lavine, K.J.1    White, A.C.2    Park, C.3    Smith, C.S.4    Choi, K.5    Long, F.6    Hui, C.C.7    Ornitz, D.M.8
  • 30
    • 0034754894 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 2 (Fgfr2) plays an important role in eyelid and skin formation and patterning
    • Li C., Guo H., Xu X., Weinberg W., and Deng C.X. Fibroblast growth factor receptor 2 (Fgfr2) plays an important role in eyelid and skin formation and patterning. Dev. Dyn. 222 (2001) 471-483
    • (2001) Dev. Dyn. , vol.222 , pp. 471-483
    • Li, C.1    Guo, H.2    Xu, X.3    Weinberg, W.4    Deng, C.X.5
  • 31
    • 0035691974 scopus 로고    scopus 로고
    • FGF-induced lens cell proliferation and differentiation is dependent on MAPK (ERK1/2) signalling
    • Lovicu F.J., and McAvoy J.W. FGF-induced lens cell proliferation and differentiation is dependent on MAPK (ERK1/2) signalling. Development 128 (2001) 5075-5084
    • (2001) Development , vol.128 , pp. 5075-5084
    • Lovicu, F.J.1    McAvoy, J.W.2
  • 32
    • 0031595782 scopus 로고    scopus 로고
    • Overlapping effects of different members of the FGF family on lens fiber differentiation in transgenic mice
    • Lovicu F.J., and Overbeek P.A. Overlapping effects of different members of the FGF family on lens fiber differentiation in transgenic mice. Development 125 (1998) 3365-3377
    • (1998) Development , vol.125 , pp. 3365-3377
    • Lovicu, F.J.1    Overbeek, P.A.2
  • 33
    • 0024458628 scopus 로고
    • Fibroblast growth factor (FGF) induces different responses in lens epithelial cells depending on its concentration
    • McAvoy J.W., and Chamberlain C.G. Fibroblast growth factor (FGF) induces different responses in lens epithelial cells depending on its concentration. Development 107 (1989) 221-228
    • (1989) Development , vol.107 , pp. 221-228
    • McAvoy, J.W.1    Chamberlain, C.G.2
  • 34
    • 0027934570 scopus 로고
    • p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
    • Morgenbesser S.D., Williams B.O., Jacks T., and DePinho R.A. p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature 371 (1994) 72-74
    • (1994) Nature , vol.371 , pp. 72-74
    • Morgenbesser, S.D.1    Williams, B.O.2    Jacks, T.3    DePinho, R.A.4
  • 35
    • 0030010591 scopus 로고    scopus 로고
    • Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
    • Nakayama K., Ishida N., Shirane M., Inomata A., Inoue T., Shishido N., Horii I., Loh D.Y., and Nakayama K. Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 85 (1996) 707-720
    • (1996) Cell , vol.85 , pp. 707-720
    • Nakayama, K.1    Ishida, N.2    Shirane, M.3    Inomata, A.4    Inoue, T.5    Shishido, N.6    Horii, I.7    Loh, D.Y.8    Nakayama, K.9
  • 37
    • 0032521460 scopus 로고    scopus 로고
    • Sox1 directly regulates the gamma-crystallin genes and is essential for lens development in mice
    • Nishiguchi S., Wood H., Kondoh H., Lovell-Badge R., and Episkopou V. Sox1 directly regulates the gamma-crystallin genes and is essential for lens development in mice. Genes Dev. 12 (1998) 776-781
    • (1998) Genes Dev. , vol.12 , pp. 776-781
    • Nishiguchi, S.1    Wood, H.2    Kondoh, H.3    Lovell-Badge, R.4    Episkopou, V.5
  • 39
    • 33846157731 scopus 로고    scopus 로고
    • Heparan sulfate biosynthetic gene Ndst1 is required for FGF signaling in early lens development
    • Pan Y., Woodbury A., Esko J.D., Grobe K., and Zhang X. Heparan sulfate biosynthetic gene Ndst1 is required for FGF signaling in early lens development. Development 133 (2006) 4933-4944
    • (2006) Development , vol.133 , pp. 4933-4944
    • Pan, Y.1    Woodbury, A.2    Esko, J.D.3    Grobe, K.4    Zhang, X.5
  • 42
    • 0035281514 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 2-IIIb acts upstream of Shh and Fgf4 and is required for limb bud maintenance but not for the induction of Fgf8, Fgf10, Msx1, or Bmp4
    • Revest J.M., Spencer-Dene B., Kerr K., De Moerlooze L., Rosewell I., and Dickson C. Fibroblast growth factor receptor 2-IIIb acts upstream of Shh and Fgf4 and is required for limb bud maintenance but not for the induction of Fgf8, Fgf10, Msx1, or Bmp4. Dev. Biol. 231 (2001) 47-62
    • (2001) Dev. Biol. , vol.231 , pp. 47-62
    • Revest, J.M.1    Spencer-Dene, B.2    Kerr, K.3    De Moerlooze, L.4    Rosewell, I.5    Dickson, C.6
  • 43
    • 0033967140 scopus 로고    scopus 로고
    • Regulation of mouse lens fiber cell development and differentiation by the Maf gene
    • Ring B.Z., Cordes S.P., Overbeek P.A., and Barsh G.S. Regulation of mouse lens fiber cell development and differentiation by the Maf gene. Development 127 (2000) 307-317
    • (2000) Development , vol.127 , pp. 307-317
    • Ring, B.Z.1    Cordes, S.P.2    Overbeek, P.A.3    Barsh, G.S.4
  • 44
    • 33846401811 scopus 로고    scopus 로고
    • An essential role for FGF receptor signaling in lens development
    • Robinson M.L. An essential role for FGF receptor signaling in lens development. Semin. Cell. Dev. Biol. 17 (2006) 726-740
    • (2006) Semin. Cell. Dev. Biol. , vol.17 , pp. 726-740
    • Robinson, M.L.1
  • 45
    • 0029610005 scopus 로고
    • Expression of a truncated FGF receptor results in defective lens development in transgenic mice
    • Robinson M.L., MacMillan-Crow L.A., Thompson J.A., and Overbeek P.A. Expression of a truncated FGF receptor results in defective lens development in transgenic mice. Development 121 (1995) 3959-3967
    • (1995) Development , vol.121 , pp. 3959-3967
    • Robinson, M.L.1    MacMillan-Crow, L.A.2    Thompson, J.A.3    Overbeek, P.A.4
  • 48
    • 0034650727 scopus 로고    scopus 로고
    • Disruption of lens fiber cell differentiation and survival at multiple stages by region-specific expression of truncated FGF receptors
    • Stolen C.M., and Griep A.E. Disruption of lens fiber cell differentiation and survival at multiple stages by region-specific expression of truncated FGF receptors. Dev. Biol. 217 (2000) 205-220
    • (2000) Dev. Biol. , vol.217 , pp. 205-220
    • Stolen, C.M.1    Griep, A.E.2
  • 49
    • 0030731702 scopus 로고    scopus 로고
    • Overexpression of FGF-2 modulates fiber cell differentiation and survival in the mouse lens
    • Stolen C.M., Jackson M.W., and Griep A.E. Overexpression of FGF-2 modulates fiber cell differentiation and survival in the mouse lens. Development 124 (1997) 4009-4017
    • (1997) Development , vol.124 , pp. 4009-4017
    • Stolen, C.M.1    Jackson, M.W.2    Griep, A.E.3
  • 50
    • 0037227318 scopus 로고    scopus 로고
    • Fgfr1 regulates patterning of the pharyngeal region
    • Trokovic N., Trokovic R., Mai P., and Partanen J. Fgfr1 regulates patterning of the pharyngeal region. Genes Dev. 17 (2003) 141-153
    • (2003) Genes Dev. , vol.17 , pp. 141-153
    • Trokovic, N.1    Trokovic, R.2    Mai, P.3    Partanen, J.4
  • 52
    • 0033602739 scopus 로고    scopus 로고
    • bFGF suppresses serum-deprivation-induced apoptosis in a human lens epithelial cell line
    • Wang Y., He H., Zigler Jr. J.S., Iwata T., Ibaraki N., Reddy V.N., and Carper D. bFGF suppresses serum-deprivation-induced apoptosis in a human lens epithelial cell line. Exp. Cell Res. 249 (1999) 123-130
    • (1999) Exp. Cell Res. , vol.249 , pp. 123-130
    • Wang, Y.1    He, H.2    Zigler Jr., J.S.3    Iwata, T.4    Ibaraki, N.5    Reddy, V.N.6    Carper, D.7
  • 54
    • 0031700905 scopus 로고    scopus 로고
    • FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung
    • Weinstein M., Xu X., Ohyama K., and Deng C.X. FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung. Development 125 (1998) 3615-3623
    • (1998) Development , vol.125 , pp. 3615-3623
    • Weinstein, M.1    Xu, X.2    Ohyama, K.3    Deng, C.X.4
  • 55
    • 0033018615 scopus 로고    scopus 로고
    • Prox1 function is crucial for mouse lens-fibre elongation
    • Wigle J.T., Chowdhury K., Gruss P., and Oliver G. Prox1 function is crucial for mouse lens-fibre elongation. Nat. Genet. 21 (1999) 318-322
    • (1999) Nat. Genet. , vol.21 , pp. 318-322
    • Wigle, J.T.1    Chowdhury, K.2    Gruss, P.3    Oliver, G.4
  • 56
    • 0031885801 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction
    • Xu X., Weinstein M., Li C., Naski M., Cohen R.I., Ornitz D.M., Leder P., and Deng C. Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction. Development 125 (1998) 753-765
    • (1998) Development , vol.125 , pp. 753-765
    • Xu, X.1    Weinstein, M.2    Li, C.3    Naski, M.4    Cohen, R.I.5    Ornitz, D.M.6    Leder, P.7    Deng, C.8
  • 58
    • 0038782306 scopus 로고    scopus 로고
    • Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth
    • Yu K., Xu J., Liu Z., Sosic D., Shao J., Olson E.N., Towler D.A., and Ornitz D.M. Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development 130 (2003) 3063-3074
    • (2003) Development , vol.130 , pp. 3063-3074
    • Yu, K.1    Xu, J.2    Liu, Z.3    Sosic, D.4    Shao, J.5    Olson, E.N.6    Towler, D.A.7    Ornitz, D.M.8
  • 60
    • 0032532490 scopus 로고    scopus 로고
    • Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development
    • Zhang P., Wong C., DePinho R.A., Harper J.W., and Elledge S.J. Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development. Genes Dev. 12 (1998) 3162-3167
    • (1998) Genes Dev. , vol.12 , pp. 3162-3167
    • Zhang, P.1    Wong, C.2    DePinho, R.A.3    Harper, J.W.4    Elledge, S.J.5
  • 61
    • 33744937606 scopus 로고    scopus 로고
    • Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family
    • Zhang X., Ibrahimi O.A., Olsen S.K., Umemori H., Mohammadi M., and Ornitz D.M. Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. J. Biol. Chem. 281 (2006) 15694-15700
    • (2006) J. Biol. Chem. , vol.281 , pp. 15694-15700
    • Zhang, X.1    Ibrahimi, O.A.2    Olsen, S.K.3    Umemori, H.4    Mohammadi, M.5    Ornitz, D.M.6
  • 62
    • 3042570454 scopus 로고    scopus 로고
    • Insertion of a Pax6 consensus binding site into the alphaA-crystallin promoter acts as a lens epithelial cell enhancer in transgenic mice
    • Zhao H., Yang Y., Rizo C.M., Overbeek P.A., and Robinson M.L. Insertion of a Pax6 consensus binding site into the alphaA-crystallin promoter acts as a lens epithelial cell enhancer in transgenic mice. Invest. Ophthalmol. Vis. Sci. 45 (2004) 1930-1939
    • (2004) Invest. Ophthalmol. Vis. Sci. , vol.45 , pp. 1930-1939
    • Zhao, H.1    Yang, Y.2    Rizo, C.M.3    Overbeek, P.A.4    Robinson, M.L.5
  • 63
    • 30444441675 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 1 (Fgfr1) is not essential for lens fiber differentiation in mice
    • Zhao H., Yang Y., Partanen J., Ciruna B.G., Rossant J., and Robinson M.L. Fibroblast growth factor receptor 1 (Fgfr1) is not essential for lens fiber differentiation in mice. Mol. Vis. 12 (2006) 15-25
    • (2006) Mol. Vis. , vol.12 , pp. 15-25
    • Zhao, H.1    Yang, Y.2    Partanen, J.3    Ciruna, B.G.4    Rossant, J.5    Robinson, M.L.6


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