-
2
-
-
30044433660
-
Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice
-
Trivedi MH, Rush AJ, Wisniewski SR, et al. Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice. Am J Psychiatry. 2006;163:28-40.
-
(2006)
Am J Psychiatry.
, vol.163
, pp. 28-40
-
-
Trivedi, M.H.1
Rush, A.J.2
Wisniewski, S.R.3
-
3
-
-
0037187646
-
Neurobiology of depression
-
Nestler EJ, Barrot M, DiLeone RJ, Eisch AJ, Gold SJ, Monteggia LM. Neurobiology of depression. Neuron. 2002;34:13-25.
-
(2002)
Neuron.
, vol.34
, pp. 13-25
-
-
Nestler, E.J.1
Barrot, M.2
DiLeone, R.J.3
Eisch, A.J.4
Gold, S.J.5
Monteggia, L.M.6
-
4
-
-
0033810465
-
Genetic epidemiology of major depression: review and meta-analysis
-
Sullivan PF, Neale MC, Kendler KS. Genetic epidemiology of major depression: review and meta-analysis. Am J Psychiatry. 2000;157:1552-1562.
-
(2000)
Am J Psychiatry.
, vol.157
, pp. 1552-1562
-
-
Sullivan, P.F.1
Neale, M.C.2
Kendler, K.S.3
-
6
-
-
84879892380
-
A mega-analysis of genomewide association studies for major depressive disorder
-
Ripke S, Wray NR, Lewis CM, et al. A mega-analysis of genomewide association studies for major depressive disorder. Mol Psychiatry. 2013;18:497-511.
-
(2013)
Mol Psychiatry.
, vol.18
, pp. 497-511
-
-
Ripke, S.1
Wray, N.R.2
Lewis, C.M.3
-
7
-
-
33845516667
-
Resolving the paradox of common, harmful, heritable mental disorders: which evolutionary genetic models work best?
-
discussion 405-452
-
Keller MC, Miller G. Resolving the paradox of common, harmful, heritable mental disorders: which evolutionary genetic models work best? Behav Brain Sci. 2006;29:385-404;discussion 405-452.
-
(2006)
Behav Brain Sci.
, vol.29
, pp. 385-404
-
-
Keller, M.C.1
Miller, G.2
-
8
-
-
70450224887
-
The role of genetic variation in the causation of mental illness: an evolution-informed framework
-
Uher R. The role of genetic variation in the causation of mental illness: an evolution-informed framework. Mol Psychiatry. 2009;14:1072- 1082.
-
(2009)
Mol Psychiatry.
, vol.14
, pp. 1072- 1082
-
-
Uher, R.1
-
10
-
-
83855163995
-
Uncovering the role of 5-hydroxymethylcytosine in the epigenome
-
Branco MR, Ficz G, Reik W. Uncovering the role of 5-hydroxymethylcytosine in the epigenome. Nat Rev Genet. 2011;13:7-13.
-
(2011)
Nat Rev Genet.
, vol.13
, pp. 7-13
-
-
Branco, M.R.1
Ficz, G.2
Reik, W.3
-
12
-
-
84871964302
-
Fecundity of patients with schizophrenia, autism, bipolar disorder, depression, anorexia nervosa, or substance abuse vs their unaffected siblings
-
Power RA, Kyaga S, Uher R, et al. Fecundity of patients with schizophrenia, autism, bipolar disorder, depression, anorexia nervosa, or substance abuse vs their unaffected siblings. JAMA Psychiatry. 2013;70:22-30.
-
(2013)
JAMA Psychiatry.
, vol.70
, pp. 22-30
-
-
Power, R.A.1
Kyaga, S.2
Uher, R.3
-
13
-
-
84898854769
-
The role of DNA methylation in stress-related psychiatric disorders
-
Klengel T, Pape J, Binder EB, Mehta D. The role of DNA methylation in stress-related psychiatric disorders. Neuropharmacology. 2014;80:115-132.
-
(2014)
Neuropharmacology.
, vol.80
, pp. 115-132
-
-
Klengel, T.1
Pape, J.2
Binder, E.B.3
Mehta, D.4
-
15
-
-
84983711696
-
Studies on the chemical nature of the substance inducing transformation of pneumococcal types: induction of transformation by a desoxyribonucleic acid fraction isolated from pneumococcus type III
-
Avery OT, Macleod CM, McCarty M. Studies on the chemical nature of the substance inducing transformation of pneumococcal types: induction of transformation by a desoxyribonucleic acid fraction isolated from pneumococcus type III. J Exp Med. 1944;79:137-158.
-
(1944)
J Exp Med.
, vol.79
, pp. 137-158
-
-
Avery, O.T.1
Macleod, C.M.2
McCarty, M.3
-
16
-
-
84956944553
-
Studies on the chemical nature of the substance inducing transformation of pneumococcal types: II. Effect of desoxyribonuclease on the biological activity of the transforming substance.
-
McCarty M, Avery OT. Studies on the chemical nature of the substance inducing transformation of pneumococcal types: II. Effect of desoxyribonuclease on the biological activity of the transforming substance. J Exp Med. 1946;83:89-96.
-
(1946)
J Exp Med.
, vol.83
, pp. 89-96
-
-
McCarty, M.1
Avery, O.T.2
-
18
-
-
80053304450
-
High density DNA methylation array with single CpG site resolution
-
Bibikova M, Barnes B, Tsan C, et al. High density DNA methylation array with single CpG site resolution. Genomics. 2011;98:288-295.
-
(2011)
Genomics.
, vol.98
, pp. 288-295
-
-
Bibikova, M.1
Barnes, B.2
Tsan, C.3
-
19
-
-
77954725166
-
Genes learn from stress: How infantile trauma programs us for depression
-
Murgatroyd C, Wu Y, Bockmuhl Y, Spengler D. Genes learn from stress: How infantile trauma programs us for depression. Epigenetics. 2010;5:194-199.
-
(2010)
Epigenetics.
, vol.5
, pp. 194-199
-
-
Murgatroyd, C.1
Wu, Y.2
Bockmuhl, Y.3
Spengler, D.4
-
20
-
-
0037372003
-
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
-
Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet. 2003;33(suppl):245-254.
-
(2003)
Nat Genet.
, vol.33
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
21
-
-
34250188803
-
Genomic patterns of DNA methylation: targets and function of an epigenetic mark
-
Weber M, Schubeler D. Genomic patterns of DNA methylation: targets and function of an epigenetic mark. Curr Opin Cell Biol. 2007;19:273- 280.
-
(2007)
Curr Opin Cell Biol.
, vol.19
, pp. 273- 280
-
-
Weber, M.1
Schubeler, D.2
-
23
-
-
84892763878
-
Reversing DNA methylation: mechanisms, genomics, and biological functions
-
Wu H, Zhang Y. Reversing DNA methylation: mechanisms, genomics, and biological functions. Cell. 2014;156:45-68.
-
(2014)
Cell.
, vol.156
, pp. 45-68
-
-
Wu, H.1
Zhang, Y.2
-
24
-
-
84892690160
-
Transcription factor occupancy can mediate active turnover of DNA methylation at regulatory regions
-
Feldmann A, Ivanek R, Murr R, Gaidatzis D, Burger L, Schubeler D. Transcription factor occupancy can mediate active turnover of DNA methylation at regulatory regions. PLoS Genet. 2013;9:e1003994.
-
(2013)
PLoS Genet.
, vol.9
-
-
Feldmann, A.1
Ivanek, R.2
Murr, R.3
Gaidatzis, D.4
Burger, L.5
Schubeler, D.6
-
25
-
-
13244276460
-
Epigenetic mechanisms in memory formation
-
Levenson JM, Sweatt JD. Epigenetic mechanisms in memory formation. Nat Rev Neurosci. 2005;6:108-118.
-
(2005)
Nat Rev Neurosci.
, vol.6
, pp. 108-118
-
-
Levenson, J.M.1
Sweatt, J.D.2
-
26
-
-
84884564612
-
Exploring epigenetic regulation of fear memory and biomarkers associated with post-traumatic stress disorder
-
Maddox SA, Schafe GE, Ressler KJ. Exploring epigenetic regulation of fear memory and biomarkers associated with post-traumatic stress disorder. Front Psychiatry. 2013;4:62.
-
(2013)
Front Psychiatry.
, vol.4
, pp. 62
-
-
Maddox, S.A.1
Schafe, G.E.2
Ressler, K.J.3
-
27
-
-
33847614418
-
Covalent modification of DNA regulates memory formation
-
Miller CA, Sweatt JD. Covalent modification of DNA regulates memory formation. Neuron. 2007;53:857-869.
-
(2007)
Neuron.
, vol.53
, pp. 857-869
-
-
Miller, C.A.1
Sweatt, J.D.2
-
28
-
-
84901291138
-
The genome in three dimensions: a new frontier in human brain research
-
Mitchell AC, Bharadwaj R, Whittle C, et al. The genome in three dimensions: a new frontier in human brain research. Biol Psychiatry. 2013;75:961-969.
-
(2013)
Biol Psychiatry.
, vol.75
, pp. 961-969
-
-
Mitchell, A.C.1
Bharadwaj, R.2
Whittle, C.3
-
29
-
-
34548319329
-
Molecular studies of major depressive disorder: the epigenetic perspective
-
Mill J, Petronis A. Molecular studies of major depressive disorder: the epigenetic perspective. Mol Psychiatry. 2007;12:799-814.
-
(2007)
Mol Psychiatry.
, vol.12
, pp. 799-814
-
-
Mill, J.1
Petronis, A.2
-
30
-
-
84868134636
-
The signature of maternal rearing in the methylome in rhesus macaque prefrontal cortex and T cells
-
Provencal N, Suderman MJ, Guillemin C, et al. The signature of maternal rearing in the methylome in rhesus macaque prefrontal cortex and T cells. J Neurosci. 2012;32:15626-15642.
-
(2012)
J Neurosci.
, vol.32
, pp. 15626-15642
-
-
Provencal, N.1
Suderman, M.J.2
Guillemin, C.3
-
31
-
-
84871717397
-
Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions
-
Klengel T, Mehta D, Anacker C, et al. Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions. Nat Neurosci. 2013;16:33-41.
-
(2013)
Nat Neurosci.
, vol.16
, pp. 33-41
-
-
Klengel, T.1
Mehta, D.2
Anacker, C.3
-
32
-
-
84872236734
-
Conserved epigenetic sensitivity to early life experience in the rat and human hippocampus
-
Suderman M, McGowan PO, Sasaki A, et al. Conserved epigenetic sensitivity to early life experience in the rat and human hippocampus. Proc Natl Acad Sci U S A. 2012;109(suppl 2):17266-17272.
-
(2012)
Proc Natl Acad Sci U S A.
, vol.109
, pp. 17266-17272
-
-
Suderman, M.1
McGowan, P.O.2
Sasaki, A.3
-
33
-
-
83755180447
-
Increased methylation of glucocorticoid receptor gene (NR3C1) in adults with a history of childhood maltreatment: a link with the severity and type of trauma
-
Perroud N, Paoloni-Giacobino A, Prada P, et al. Increased methylation of glucocorticoid receptor gene (NR3C1) in adults with a history of childhood maltreatment: a link with the severity and type of trauma. Transl Psychiatry. 2011;1:e59.
-
(2011)
Transl Psychiatry.
, vol.1
-
-
Perroud, N.1
Paoloni-Giacobino, A.2
Prada, P.3
-
34
-
-
84855300158
-
Genome-wide epigenetic regulation by early-life trauma
-
Labonte B, Suderman M, Maussion G, et al. Genome-wide epigenetic regulation by early-life trauma. Arch Gen Psychiatry. 2012;69:722-731.
-
(2012)
Arch Gen Psychiatry.
, vol.69
, pp. 722-731
-
-
Labonte, B.1
Suderman, M.2
Maussion, G.3
-
35
-
-
60749105468
-
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
-
McGowan PO, Sasaki A, D'Alessio AC, et al. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci. 2009;12:342-348.
-
(2009)
Nat Neurosci.
, vol.12
, pp. 342-348
-
-
McGowan, P.O.1
Sasaki, A.2
D'Alessio, A.C.3
-
36
-
-
84880538825
-
Genetic and epigenetic associations of MAOA and NR3C1 with depression and childhood adversities
-
Melas PA, Wei Y, Wong CC, et al. Genetic and epigenetic associations of MAOA and NR3C1 with depression and childhood adversities. Int J Neuropsychopharmacol. 2013;16:1513-1528.
-
(2013)
Int J Neuropsychopharmacol.
, vol.16
, pp. 1513-1528
-
-
Melas, P.A.1
Wei, Y.2
Wong, C.C.3
-
37
-
-
0034351371
-
5'-heterogeneity of glucocorticoid receptor messenger RNA is tissue specific: differential regulation of variant transcripts by early-life events
-
McCormick JA, Lyons V, Jacobson MD, et al. 5'-heterogeneity of glucocorticoid receptor messenger RNA is tissue specific: differential regulation of variant transcripts by early-life events. Mol Endocrinol. 2000;14:506- 517.
-
(2000)
Mol Endocrinol.
, vol.14
, pp. 506- 517
-
-
McCormick, J.A.1
Lyons, V.2
Jacobson, M.D.3
-
39
-
-
40949142290
-
Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults
-
Binder EB, Bradley RG, Liu W, et al. Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. JAMA. 2008;299:1291-1305.
-
(2008)
JAMA.
, vol.299
, pp. 1291-1305
-
-
Binder, E.B.1
Bradley, R.G.2
Liu, W.3
-
40
-
-
84856277610
-
Childhood adversity and epigenetic modulation of the leukocyte glucocorticoid receptor: preliminary findings in healthy adults
-
Tyrka AR, Price LH, Marsit C, Walters OC, Carpenter LL. Childhood adversity and epigenetic modulation of the leukocyte glucocorticoid receptor: preliminary findings in healthy adults. PLoS One. 2012;7:e30148.
-
(2012)
PLoS One.
, vol.7
-
-
Tyrka, A.R.1
Price, L.H.2
Marsit, C.3
Walters, O.C.4
Carpenter, L.L.5
-
41
-
-
77950689477
-
Differential expression of glucocorticoid receptor transcripts in major depressive disorder is not epigenetically programmed
-
Alt SR, Turner JD, Klok MD, et al. Differential expression of glucocorticoid receptor transcripts in major depressive disorder is not epigenetically programmed. Psychoneuroendocrinology. 2010;35:544-556.
-
(2010)
Psychoneuroendocrinology.
, vol.35
, pp. 544-556
-
-
Alt, S.R.1
Turner, J.D.2
Klok, M.D.3
-
42
-
-
84866975209
-
Environmental stress affects DNA methylation of a CpG rich promoter region of serotonin transporter gene in a nurse cohort
-
Alasaari JS, Lagus M, Ollila HM, et al. Environmental stress affects DNA methylation of a CpG rich promoter region of serotonin transporter gene in a nurse cohort. PLoS One. 2012;7:e45813.
-
(2012)
PLoS One.
, vol.7
-
-
Alasaari, J.S.1
Lagus, M.2
Ollila, H.M.3
-
43
-
-
84873918555
-
Association of SLC6A4 methylation with early adversity, characteristics and outcomes in depression
-
Kang HJ, Kim JM, Stewart R, et al. Association of SLC6A4 methylation with early adversity, characteristics and outcomes in depression. Prog Neuropsychopharmacol Biol Psychiatry. 2013;44:23-28.
-
(2013)
Prog Neuropsychopharmacol Biol Psychiatry.
, vol.44
, pp. 23-28
-
-
Kang, H.J.1
Kim, J.M.2
Stewart, R.3
-
44
-
-
84880571578
-
Association between promoter methylation of serotonin transporter gene and depressive symptoms: a monozygotic twin study
-
Zhao J, Goldberg J, Bremner JD, Vaccarino V. Association between promoter methylation of serotonin transporter gene and depressive symptoms: a monozygotic twin study. Psychosom Med. 2013;75:523-529.
-
(2013)
Psychosom Med.
, vol.75
, pp. 523-529
-
-
Zhao, J.1
Goldberg, J.2
Bremner, J.D.3
Vaccarino, V.4
-
45
-
-
84880134687
-
A longitudinal study of SLC6A4 DNA promoter methylation and poststroke depression
-
Kim JM, Stewart R, Kang HJ, et al. A longitudinal study of SLC6A4 DNA promoter methylation and poststroke depression. J Psychiatr Res. 2013;47:1222-1227.
-
(2013)
J Psychiatr Res.
, vol.47
, pp. 1222-1227
-
-
Kim, J.M.1
Stewart, R.2
Kang, H.J.3
-
46
-
-
77957970301
-
Epigenetic modifications and human disease
-
Portela A, Esteller M. Epigenetic modifications and human disease. Nat Biotechnol. 2010;28:1057-1068.
-
(2010)
Nat Biotechnol.
, vol.28
, pp. 1057-1068
-
-
Portela, A.1
Esteller, M.2
-
47
-
-
80455176999
-
CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing
-
Shukla S, Kavak E, Gregory M, et al. CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing. Nature. 2011;479:74-79.
-
(2011)
Nature.
, vol.479
, pp. 74-79
-
-
Shukla, S.1
Kavak, E.2
Gregory, M.3
-
48
-
-
84877850278
-
Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder
-
Mehta D, Klengel T, Conneely KN, et al. Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder. Proc Natl Acad Sci U S A. 2013;110:8302-8307.
-
(2013)
Proc Natl Acad Sci U S A.
, vol.110
, pp. 8302-8307
-
-
Mehta, D.1
Klengel, T.2
Conneely, K.N.3
-
49
-
-
0034927081
-
Neurotrophins: roles in neuronal development and function
-
Huang EJ, Reichardt LF. Neurotrophins: roles in neuronal development and function. Annu Rev Neurosci. 2001;24:677-736.
-
(2001)
Annu Rev Neurosci.
, vol.24
, pp. 677-736
-
-
Huang, E.J.1
Reichardt, L.F.2
-
50
-
-
84879132439
-
BDNF and CREB1 genetic variants interact to affect antidepressant treatment outcomes in geriatric depression
-
Murphy GM Jr, Sarginson JE, Ryan HS, O'Hara R, Schatzberg AF, Lazzeroni LC. BDNF and CREB1 genetic variants interact to affect antidepressant treatment outcomes in geriatric depression. Pharmacogenet Genomics. 2013;23:301-313.
-
(2013)
Pharmacogenet Genomics.
, vol.23
, pp. 301-313
-
-
Murphy Jr., G.M.1
Sarginson, J.E.2
Ryan, H.S.3
O'Hara, R.4
Schatzberg, A.F.5
Lazzeroni, L.C.6
-
51
-
-
84886686112
-
Gene expression: biomarker of antidepressant therapy?
-
Menke A. Gene expression: biomarker of antidepressant therapy? Int Rev Psychiatry. 2013;25:579-591.
-
(2013)
Int Rev Psychiatry.
, vol.25
, pp. 579-591
-
-
Menke, A.1
-
52
-
-
84885476091
-
BDNF promoter methylation and suicidal behavior in depressive patients
-
Kang HJ, Kim JM, Lee JY, et al. BDNF promoter methylation and suicidal behavior in depressive patients. J Affect Disord. 2013;151:679-685.
-
(2013)
J Affect Disord.
, vol.151
, pp. 679-685
-
-
Kang, H.J.1
Kim, J.M.2
Lee, J.Y.3
-
53
-
-
77649194621
-
Increased BDNF promoter methylation in the Wernicke area of suicide subjects
-
Keller S, Sarchiapone M, Zarrilli F, et al. Increased BDNF promoter methylation in the Wernicke area of suicide subjects. Arch Gen Psychiatry. 2010;67:258-267.
-
(2010)
Arch Gen Psychiatry.
, vol.67
, pp. 258-267
-
-
Keller, S.1
Sarchiapone, M.2
Zarrilli, F.3
-
54
-
-
80052287594
-
DNA methylation profiles of the brain-derived neurotrophic factor (BDNF) gene as a potent diagnostic biomarker in major depression
-
Fuchikami M, Morinobu S, Segawa M, et al. DNA methylation profiles of the brain-derived neurotrophic factor (BDNF) gene as a potent diagnostic biomarker in major depression. PLoS One. 2011;6:e23881.
-
(2011)
PLoS One.
, vol.6
-
-
Fuchikami, M.1
Morinobu, S.2
Segawa, M.3
-
55
-
-
84880869360
-
Response to psychotherapy in borderline personality disorder and methylation status of the BDNF gene
-
Perroud N, Salzmann A, Prada P, et al. Response to psychotherapy in borderline personality disorder and methylation status of the BDNF gene. Transl Psychiatry. 2013;3:e207.
-
(2013)
Transl Psychiatry.
, vol.3
-
-
Perroud, N.1
Salzmann, A.2
Prada, P.3
-
56
-
-
68349091505
-
The early life environment and the epigenome
-
Szyf M. The early life environment and the epigenome. Biochim Biophys Acta. 2009;1790:878-885.
-
(2009)
Biochim Biophys Acta.
, vol.1790
, pp. 878-885
-
-
Szyf, M.1
-
57
-
-
75749138038
-
Valproate and amitriptyline exert common and divergent influences on global and gene promoter- specific chromatin modifications in rat primary astrocytes
-
Perisic T, Zimmermann N, Kirmeier T, et al. Valproate and amitriptyline exert common and divergent influences on global and gene promoter- specific chromatin modifications in rat primary astrocytes. Neuropsychopharmacology. 2010;35:792-805.
-
(2010)
Neuropsychopharmacology.
, vol.35
, pp. 792-805
-
-
Perisic, T.1
Zimmermann, N.2
Kirmeier, T.3
-
58
-
-
84867792647
-
Antidepressants inhibit DNA methyltransferase 1 through reducing G9a levels
-
Zimmermann N, Zschocke J, Perisic T, Yu S, Holsboer F, Rein T. Antidepressants inhibit DNA methyltransferase 1 through reducing G9a levels. Biochem J. 2012;448:93-102.
-
(2012)
Biochem J.
, vol.448
, pp. 93-102
-
-
Zimmermann, N.1
Zschocke, J.2
Perisic, T.3
Yu, S.4
Holsboer, F.5
Rein, T.6
-
59
-
-
0033541022
-
Impaired methionine synthesis and hypomethylation in rats exposed to valproate during gestation
-
Alonso-Aperte E, Ubeda N, Achon M, Perez-Miguelsanz J, Varela- Moreiras G. Impaired methionine synthesis and hypomethylation in rats exposed to valproate during gestation. Neurology. 1999;52:750-756.
-
(1999)
Neurology.
, vol.52
, pp. 750-756
-
-
Alonso-Aperte, E.1
Ubeda, N.2
Achon, M.3
Perez-Miguelsanz, J.4
Varela-Moreiras, G.5
-
60
-
-
0042346416
-
Valproate induces replication-independent active DNA demethylation
-
Detich N, Bovenzi V, Szyf M. Valproate induces replication-independent active DNA demethylation. J Biol Chem. 2003;278:27586-27592.
-
(2003)
J Biol Chem.
, vol.278
, pp. 27586-27592
-
-
Detich, N.1
Bovenzi, V.2
Szyf, M.3
-
61
-
-
51649127761
-
Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation
-
Dong E, Nelson M, Grayson DR, Costa E, Guidotti A. Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation. Proc Natl Acad Sci U S A. 2008;105:13614-13619.
-
(2008)
Proc Natl Acad Sci U S A.
, vol.105
, pp. 13614-13619
-
-
Dong, E.1
Nelson, M.2
Grayson, D.R.3
Costa, E.4
Guidotti, A.5
-
62
-
-
80054848287
-
Serum levels of brainderived neurotrophic factor in major depressive disorder: state-trait issues, clinical features and pharmacological treatment
-
Molendijk ML, Bus BA, Spinhoven P, et al. Serum levels of brainderived neurotrophic factor in major depressive disorder: state-trait issues, clinical features and pharmacological treatment. Mol Psychiatry. 2011;16:1088-1095.
-
(2011)
Mol Psychiatry.
, vol.16
, pp. 1088-1095
-
-
Molendijk, M.L.1
Bus, B.A.2
Spinhoven, P.3
-
63
-
-
79952901686
-
The early non-increase of serum BDNF predicts failure of antidepressant treatment in patients with major depression: a pilot study
-
Tadic A, Wagner S, Schlicht KF, et al. The early non-increase of serum BDNF predicts failure of antidepressant treatment in patients with major depression: a pilot study. Prog Neuropsychopharmacol Biol Psychiatry. 2011;35:415-420.
-
(2011)
Prog Neuropsychopharmacol Biol Psychiatry.
, vol.35
, pp. 415-420
-
-
Tadic, A.1
Wagner, S.2
Schlicht, K.F.3
-
64
-
-
84894558937
-
Methylation of the promoter of brain-derived neurotrophic factor exon IV and antidepressant response in major depression
-
Tadic A, Muller-Engling L, Schlicht KF, et al. Methylation of the promoter of brain-derived neurotrophic factor exon IV and antidepressant response in major depression. Mol Psychiatry. 2013;19:281-283.
-
(2013)
Mol Psychiatry.
, vol.19
, pp. 281-283
-
-
Tadic, A.1
Muller-Engling, L.2
Schlicht, K.F.3
-
65
-
-
84884211454
-
Epigenetic regulation of BDNF expression according to antidepressant response
-
Lopez JP, Mamdani F, Labonte B, et al. Epigenetic regulation of BDNF expression according to antidepressant response. Mol Psychiatry. 2013;18:398-399.
-
(2013)
Mol Psychiatry.
, vol.18
, pp. 398-399
-
-
Lopez, J.P.1
Mamdani, F.2
Labonte, B.3
-
66
-
-
84885344455
-
Epigenetic biomarkers as predictors and correlates of symptom improvement following psychotherapy in combat veterans with PTSD
-
Yehuda R, Daskalakis NP, Desarnaud F, et al. Epigenetic biomarkers as predictors and correlates of symptom improvement following psychotherapy in combat veterans with PTSD. Front Psychiatry. 2013;4:118.
-
(2013)
Front Psychiatry.
, vol.4
, pp. 118
-
-
Yehuda, R.1
Daskalakis, N.P.2
Desarnaud, F.3
-
67
-
-
70449413781
-
Status of glucocorticoid alterations in post-traumatic stress disorder
-
Yehuda R. Status of glucocorticoid alterations in post-traumatic stress disorder. Ann N Y Acad Sci. 2009;1179:56-69.
-
(2009)
Ann N Y Acad Sci.
, vol.1179
, pp. 56-69
-
-
Yehuda, R.1
-
68
-
-
84927566175
-
Serotonin transporter gene hypomethylation predicts impaired antidepressant treatment response
-
Domschke K, Tidow N, Schwarte K, et al. Serotonin transporter gene hypomethylation predicts impaired antidepressant treatment response. Int J Neuropsychopharmacol. 2014;17:1167-1176.
-
(2014)
Int J Neuropsychopharmacol.
, vol.17
, pp. 1167-1176
-
-
Domschke, K.1
Tidow, N.2
Schwarte, K.3
-
69
-
-
77951779878
-
Genome-wide pharmacogenetics of antidepressant response in the GENDEP project
-
Uher R, Perroud N, Ng MY, et al. Genome-wide pharmacogenetics of antidepressant response in the GENDEP project. Am J Psychiatry. 2010;167:555-564.
-
(2010)
Am J Psychiatry.
, vol.167
, pp. 555-564
-
-
Uher, R.1
Perroud, N.2
Ng, M.Y.3
-
70
-
-
67849116132
-
Genetic predictors of response to antidepressants in the GENDEP project
-
Uher R, Huezo-Diaz P, Perroud N, et al. Genetic predictors of response to antidepressants in the GENDEP project. Pharmacogenomics J. 2009;9:225-233.
-
(2009)
Pharmacogenomics J.
, vol.9
, pp. 225-233
-
-
Uher, R.1
Huezo-Diaz, P.2
Perroud, N.3
-
71
-
-
84893517465
-
DNA methylation in interleukin-11 predicts clinical response to antidepressants in GENDEP
-
Powell TR, Smith RG, Hackinger S, et al. DNA methylation in interleukin-11 predicts clinical response to antidepressants in GENDEP. Transl Psychiatry. 2013;3:e300.
-
(2013)
Transl Psychiatry.
, vol.3
-
-
Powell, T.R.1
Smith, R.G.2
Hackinger, S.3
-
72
-
-
0347123629
-
Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases
-
Waterland RA, Jirtle RL. Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases. Nutrition. 2004;20:63-68.
-
(2004)
Nutrition.
, vol.20
, pp. 63-68
-
-
Waterland, R.A.1
Jirtle, R.L.2
-
74
-
-
62449271516
-
The role of L-methylfolate in depressive disorders
-
Farah A. The role of L-methylfolate in depressive disorders. CNS Spectr. 2009;14:2-7.
-
(2009)
CNS Spectr.
, vol.14
, pp. 2-7
-
-
Farah, A.1
-
75
-
-
0033858407
-
Enhancement of the antidepressant action of fluoxetine by folic acid: a randomised, placebo controlled trial
-
Coppen A, Bailey J. Enhancement of the antidepressant action of fluoxetine by folic acid: a randomised, placebo controlled trial. J Affect Disord. 2000;60:121-130.
-
(2000)
J Affect Disord.
, vol.60
, pp. 121-130
-
-
Coppen, A.1
Bailey, J.2
-
76
-
-
0025113543
-
Enhancement of recovery from psychiatric illness by methylfolate
-
Godfrey PS, Toone BK, Carney MW, et al. Enhancement of recovery from psychiatric illness by methylfolate. Lancet. 1990;336:392-395.
-
(1990)
Lancet.
, vol.336
, pp. 392-395
-
-
Godfrey, P.S.1
Toone, B.K.2
Carney, M.W.3
-
77
-
-
0031816123
-
Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women
-
Jacob RA, Gretz DM, Taylor PC, et al. Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women. J Nutr. 1998;128:1204-1212.
-
(1998)
J Nutr.
, vol.128
, pp. 1204-1212
-
-
Jacob, R.A.1
Gretz, D.M.2
Taylor, P.C.3
-
78
-
-
0033805888
-
Genomic DNA methylation decreases in response to moderate folate depletion in elderly women
-
Rampersaud GC, Kauwell GP, Hutson AD, Cerda JJ, Bailey LB. Genomic DNA methylation decreases in response to moderate folate depletion in elderly women. Am J Clin Nutr. 2000;72:998-1003.
-
(2000)
Am J Clin Nutr.
, vol.72
, pp. 998-1003
-
-
Rampersaud, G.C.1
Kauwell, G.P.2
Hutson, A.D.3
Cerda, J.J.4
Bailey, L.B.5
-
79
-
-
35448977229
-
Homocysteine regulates expression of Herp by DNA methylation involving the AARE and CREB binding sites
-
Lenz B, Bleich S, Beutler S, et al. Homocysteine regulates expression of Herp by DNA methylation involving the AARE and CREB binding sites. Exp Cell Res. 2006;312:4049-4055.
-
(2006)
Exp Cell Res.
, vol.312
, pp. 4049-4055
-
-
Lenz, B.1
Bleich, S.2
Beutler, S.3
-
80
-
-
76249099066
-
Acute homocysteine administration impairs memory consolidation on inhibitory avoidance task and decreases hippocampal brain-derived neurotrophic factor immunocontent: prevention by folic acid treatment
-
Matte C, Pereira LO, Dos Santos TM, et al. Acute homocysteine administration impairs memory consolidation on inhibitory avoidance task and decreases hippocampal brain-derived neurotrophic factor immunocontent: prevention by folic acid treatment. Neuroscience. 2009;163:1039- 1045.
-
(2009)
Neuroscience.
, vol.163
, pp. 1039- 1045
-
-
Matte, C.1
Pereira, L.O.2
Dos Santos, T.M.3
-
81
-
-
78751567821
-
Dietary methyl donors, methyl metabolizing enzymes, and epigenetic regulators: diet-gene interactions and promoter CpG island hypermethylation in colorectal cancer
-
de Vogel S, Wouters KA, Gottschalk RW, et al. Dietary methyl donors, methyl metabolizing enzymes, and epigenetic regulators: diet-gene interactions and promoter CpG island hypermethylation in colorectal cancer. Cancer Causes Control. 2011;22:1-12.
-
(2011)
Cancer Causes Control.
, vol.22
, pp. 1-12
-
-
de Vogel, S.1
Wouters, K.A.2
Gottschalk, R.W.3
-
82
-
-
34250822335
-
The homocysteine hypothesis of depression
-
Folstein M, Liu T, Peter I, et al. The homocysteine hypothesis of depression. Am J Psychiatry. 2007;164:861-867.
-
(2007)
Am J Psychiatry.
, vol.164
, pp. 861-867
-
-
Folstein, M.1
Liu, T.2
Peter, I.3
-
83
-
-
35248842731
-
Depressive symptoms may explain elevated plasma levels of homocysteine in females with eating disorders
-
Frieling H, Romer KD, Beyer S, et al. Depressive symptoms may explain elevated plasma levels of homocysteine in females with eating disorders. J Psychiatr Res. 2008;42:83-86.
-
(2008)
J Psychiatr Res.
, vol.42
, pp. 83-86
-
-
Frieling, H.1
Romer, K.D.2
Beyer, S.3
-
85
-
-
84884828422
-
Recommendations for the design and analysis of epigenome-wide association studies
-
Michels KB, Binder AM, Dedeurwaerder S, et al. Recommendations for the design and analysis of epigenome-wide association studies. Nat Methods. 2013;10:949-955.
-
(2013)
Nat Methods.
, vol.10
, pp. 949-955
-
-
Michels, K.B.1
Binder, A.M.2
Dedeurwaerder, S.3
-
86
-
-
85027954125
-
DNA methylation profiling in the clinic: applications and challenges
-
Heyn H, Esteller M. DNA methylation profiling in the clinic: applications and challenges. Nat Rev Genet. 2012;13:679-692.
-
(2012)
Nat Rev Genet.
, vol.13
, pp. 679-692
-
-
Heyn, H.1
Esteller, M.2
-
87
-
-
0034626988
-
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
-
Esteller M, Garcia-Foncillas J, Andion E, et al. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med. 2000;343:1350-1354.
-
(2000)
N Engl J Med.
, vol.343
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
-
90
-
-
82455206314
-
Evaluation of the Infinium Methylation 450K technology
-
Dedeurwaerder S, Defrance M, Calonne E, Denis H, Sotiriou C, Fuks F. Evaluation of the Infinium Methylation 450K technology. Epigenomics. 2011;3:771-784.
-
(2011)
Epigenomics.
, vol.3
, pp. 771-784
-
-
Dedeurwaerder, S.1
Defrance, M.2
Calonne, E.3
Denis, H.4
Sotiriou, C.5
Fuks, F.6
-
91
-
-
84882884517
-
Charting a dynamic DNA methylation landscape of the human genome
-
Ziller MJ, Gu H, Muller F, et al. Charting a dynamic DNA methylation landscape of the human genome. Nature. 2013;500:477-481.
-
(2013)
Nature.
, vol.500
, pp. 477-481
-
-
Ziller, M.J.1
Gu, H.2
Muller, F.3
-
92
-
-
84871768667
-
Genome-wide DNA methylation scan in major depressive disorder
-
Sabunciyan S, Aryee MJ, Irizarry RA, et al. Genome-wide DNA methylation scan in major depressive disorder. PLoS One. 2012;7:e34451.
-
(2012)
PLoS One.
, vol.7
-
-
Sabunciyan, S.1
Aryee, M.J.2
Irizarry, R.A.3
-
93
-
-
79960310830
-
Epigenetic and inflammatory marker profiles associated with depression in a community-based epidemiologic sample
-
Uddin M, Koenen KC, Aiello AE, Wildman DE, de los Santos R, Galea S. Epigenetic and inflammatory marker profiles associated with depression in a community-based epidemiologic sample. Psychol Med. 2011;41:997- 1007.
-
(2011)
Psychol Med.
, vol.41
, pp. 997- 1007
-
-
Uddin, M.1
Koenen, K.C.2
Aiello, A.E.3
Wildman, D.E.4
de los Santos, R.5
Galea, S.6
-
94
-
-
84879439091
-
Genome-wide methylation changes in the brains of suicide completers
-
Labonte B, Suderman M, Maussion G, et al. Genome-wide methylation changes in the brains of suicide completers. Am J Psychiatry. 2013;170:511-520.
-
(2013)
Am J Psychiatry.
, vol.170
, pp. 511-520
-
-
Labonte, B.1
Suderman, M.2
Maussion, G.3
-
95
-
-
84884651887
-
High-throughput genetic and gene expression analysis of the RNAPII-CTD reveals unexpected connections to SRB10/CDK8
-
Aristizabal MJ, Negri GL, Benschop JJ, Holstege FC, Krogan NJ, Kobor MS. High-throughput genetic and gene expression analysis of the RNAPII-CTD reveals unexpected connections to SRB10/CDK8. PLoS Genet. 2013;9:e1003758.
-
(2013)
PLoS Genet.
, vol.9
-
-
Aristizabal, M.J.1
Negri, G.L.2
Benschop, J.J.3
Holstege, F.C.4
Krogan, N.J.5
Kobor, M.S.6
-
96
-
-
84875700729
-
A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression
-
Guintivano J, Aryee MJ, Kaminsky ZA. A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression. Epigenetics. 2013;8:290- 302.
-
(2013)
Epigenetics.
, vol.8
, pp. 290- 302
-
-
Guintivano, J.1
Aryee, M.J.2
Kaminsky, Z.A.3
-
97
-
-
84860637797
-
DNA methylation arrays as surrogate measures of cell mixture distribution
-
Houseman EA, Accomando WP, Koestler DC, et al. DNA methylation arrays as surrogate measures of cell mixture distribution. BMC Bioinformatics. 2012;13:86.
-
(2012)
BMC Bioinformatics.
, vol.13
, pp. 86
-
-
Houseman, E.A.1
Accomando, W.P.2
Koestler, D.C.3
-
98
-
-
84873348443
-
Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies
-
GENDEP Investigators, MARS Investigators, STAR*D Investigators. Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. Am J Psychiatry. 2013;170:207-217.
-
(2013)
Am J Psychiatry.
, vol.170
, pp. 207-217
-
-
-
99
-
-
84892888839
-
Myelodysplastic syndromes: 2014 update on diagnosis, risk-stratification, and management
-
Garcia-Manero G. Myelodysplastic syndromes: 2014 update on diagnosis, risk-stratification, and management. Am J Hematol. 2014;89:97-108.
-
(2014)
Am J Hematol.
, vol.89
, pp. 97-108
-
-
Garcia-Manero, G.1
-
100
-
-
80055006970
-
Antidepressant-like effect induced by systemic and intra-hippocampal administration of DNA methylation inhibitors
-
Sales AJ, Biojone C, Terceti MS, Guimaraes FS, Gomes MV, Joca SR. Antidepressant-like effect induced by systemic and intra-hippocampal administration of DNA methylation inhibitors. Br J Pharmacol. 2011;164:1711- 1721.
-
(2011)
Br J Pharmacol.
, vol.164
, pp. 1711- 1721
-
-
Sales, A.J.1
Biojone, C.2
Terceti, M.S.3
Guimaraes, F.S.4
Gomes, M.V.5
Joca, S.R.6
-
101
-
-
84856181467
-
Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics
-
Heim C, Binder EB. Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics. Exp Neurol. 2012;233:102-111.
-
(2012)
Exp Neurol.
, vol.233
, pp. 102-111
-
-
Heim, C.1
Binder, E.B.2
|