Valproate and amitriptyline exert common and divergent influences on global and gene promoter-specific chromatin modifications in rat primary astrocytes

Neuropsychopharmacology

Volumn 35, Issue 3, 2010, Pages 792-805

  Perisic, Tatjana ^a   Zimmermann, Nicole ^a   Kirmeier, Thomas ^a   Asmus, Maria ^a   Tuorto, Francesca ^b,c   Uhr, Manfred ^a   Holsboer, Florian ^a   Rein, Theo ^a   Zschocke, Jürgen ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

Author keywords

Antidepressant; DNA methylation; Glia; GLT 1; Histone acetylation; Mood stabilizer

Indexed keywords

AMITRIPTYLINE; BISULFITE; CARBAMAZEPINE; CITALOPRAM; CYTOSINE; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 1; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; HISTONE DEACETYLASE; HISTONE H3; HISTONE H4; LAMOTRIGINE; VALPROIC ACID; VENLAFAXINE; VESICULAR GLUTAMATE TRANSPORTER 1;

ACETYLATION; ANIMAL CELL; ARTICLE; ASTROCYTE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CPG ISLAND; DEMETHYLATION; DNA METHYLATION; DNA MODIFICATION; ENZYME ACTIVITY; EPIGENETICS; GENE SEQUENCE; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT; WESTERN BLOTTING;

AMITRIPTYLINE; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CELLS, CULTURED; CHROMATIN; DNA METHYLATION; PROMOTER REGIONS, GENETIC; RATS; RATS, SPRAGUE-DAWLEY; VALPROIC ACID;

EID: 75749138038     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2009.188     Document Type: Article

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