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Volumn 164, Issue 6, 2007, Pages 861-867

The homocysteine hypothesis of depression

Author keywords

[No Author keywords available]

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; NEUROTRANSMITTER; PYRIDOXINE;

EID: 34250822335     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/ajp.2007.164.6.861     Document Type: Review
Times cited : (211)

References (104)
  • 1
    • 12444279964 scopus 로고    scopus 로고
    • Treatment of depression: Time to consider folic acid and vitamin B12
    • Coppen A, Bolander-Gouaille C: Treatment of depression: time to consider folic acid and vitamin B12. J Psychopharmacol 2005; 19:59-65
    • (2005) J Psychopharmacol , vol.19 , pp. 59-65
    • Coppen, A.1    Bolander-Gouaille, C.2
  • 2
    • 0037364417 scopus 로고    scopus 로고
    • Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders
    • Mattson MP, Shea TB: Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders. Trends Neurosci 2003; 26:137-146
    • (2003) Trends Neurosci , vol.26 , pp. 137-146
    • Mattson, M.P.1    Shea, T.B.2
  • 5
    • 0027382008 scopus 로고
    • Vitamin status and intake as primary determinants of homocysteinemia in an elderly population
    • Selhub J, Jacques PF, Wilson PW, Rush D, Rosenberg IH: Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA 1993; 270:2693-2698
    • (1993) JAMA , vol.270 , pp. 2693-2698
    • Selhub, J.1    Jacques, P.F.2    Wilson, P.W.3    Rush, D.4    Rosenberg, I.H.5
  • 7
    • 0031597388 scopus 로고    scopus 로고
    • Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease
    • Clarke R, Smith AD, Jobst KA, Refsum H, Sutton L, Ueland PM: Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease. Arch Neurol 1998; 55:1449-1455
    • (1998) Arch Neurol , vol.55 , pp. 1449-1455
    • Clarke, R.1    Smith, A.D.2    Jobst, K.A.3    Refsum, H.4    Sutton, L.5    Ueland, P.M.6
  • 9
    • 3242784006 scopus 로고    scopus 로고
    • Total homocysteine and cognition in a tri-ethnic cohort: The Northern Manhattan Study
    • Wright CB, Lee HS, Paik MC, Stabler SP, Allen RH, Sacco RL: Total homocysteine and cognition in a tri-ethnic cohort: the Northern Manhattan Study. Neurology 2004; 63:254-260
    • (2004) Neurology , vol.63 , pp. 254-260
    • Wright, C.B.1    Lee, H.S.2    Paik, M.C.3    Stabler, S.P.4    Allen, R.H.5    Sacco, R.L.6
  • 11
    • 0033178883 scopus 로고    scopus 로고
    • Total homocysteine and cognitive decline in a community-based sample of elderly subjects: The Rotterdam Study
    • Kalmijn S, Launer LJ, Lindemans J, Bots ML, Hofman A, Breteler MM: Total homocysteine and cognitive decline in a community-based sample of elderly subjects: the Rotterdam Study. Am J Epidemiol 1999; 150:283-289
    • (1999) Am J Epidemiol , vol.150 , pp. 283-289
    • Kalmijn, S.1    Launer, L.J.2    Lindemans, J.3    Bots, M.L.4    Hofman, A.5    Breteler, M.M.6
  • 12
    • 0031786776 scopus 로고    scopus 로고
    • Relation of plasma homocysteine to cerebral infarction and cerebral atherosclerosis
    • Yoo JH, Chung CS, Kang SS: Relation of plasma homocysteine to cerebral infarction and cerebral atherosclerosis. Stroke 1998; 29:2478-2483
    • (1998) Stroke , vol.29 , pp. 2478-2483
    • Yoo, J.H.1    Chung, C.S.2    Kang, S.S.3
  • 13
    • 0034445732 scopus 로고    scopus 로고
    • Relationship between plasma homocysteine and vitamin status in the Framingham study population: Impact of folic acid fortification
    • Selhub J, Jacques PF, Bostom AG, Wilson PW, Rosenberg IH: Relationship between plasma homocysteine and vitamin status in the Framingham study population: impact of folic acid fortification. Public Health Rev 2000; 28:117-145
    • (2000) Public Health Rev , vol.28 , pp. 117-145
    • Selhub, J.1    Jacques, P.F.2    Bostom, A.G.3    Wilson, P.W.4    Rosenberg, I.H.5
  • 14
    • 0037406436 scopus 로고    scopus 로고
    • Homocysteine, renal function, and risk of cardiovascular disease
    • Clarke R, Lewington, S, Landray M: Homocysteine, renal function, and risk of cardiovascular disease. Kidney Int Suppl 2003; 84:S131-S133
    • (2003) Kidney Int Suppl , vol.84
    • Clarke, R.1    Lewington, S.2    Landray, M.3
  • 16
    • 2442470422 scopus 로고    scopus 로고
    • Age-associated changes in the metabolism of vitamin B(12) and folic acid: Prevalence, aetiopathogenesis and pathophysiological consequences] (German)
    • Wolters M, Strohle A, Hahn A: [Age-associated changes in the metabolism of vitamin B(12) and folic acid: prevalence, aetiopathogenesis and pathophysiological consequences] (German). Z Gerontol Geriatr 2004; 37:109-135
    • (2004) Z Gerontol Geriatr , vol.37 , pp. 109-135
    • Wolters, M.1    Strohle, A.2    Hahn, A.3
  • 17
    • 0034933207 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and inflammatory bowel disease: Prevalence and predictors in a cross-sectional study
    • Romagnuolo J, Fedorak RN, Dias VC, Bamforth F, Teltscher M: Hyperhomocysteinemia and inflammatory bowel disease: prevalence and predictors in a cross-sectional study. Am J Gastroenterol 2001; 96:2143-2149
    • (2001) Am J Gastroenterol , vol.96 , pp. 2143-2149
    • Romagnuolo, J.1    Fedorak, R.N.2    Dias, V.C.3    Bamforth, F.4    Teltscher, M.5
  • 19
    • 0037354622 scopus 로고    scopus 로고
    • Antihypertensive treatment and homocysteine concentrations
    • Westphal S, Rading A, Luley C, Dierkes J: Antihypertensive treatment and homocysteine concentrations. Metabolism 2003; 52:261-263
    • (2003) Metabolism , vol.52 , pp. 261-263
    • Westphal, S.1    Rading, A.2    Luley, C.3    Dierkes, J.4
  • 20
    • 0014545138 scopus 로고
    • Vascular pathology of homocysteinemia: Implications for the pathogenesis of arteriosclerosis
    • McCully KS: Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis. Am J Pathol 1969; 56:111-128
    • (1969) Am J Pathol , vol.56 , pp. 111-128
    • McCully, K.S.1
  • 21
    • 0016743933 scopus 로고
    • Homocysteine theory of arteriosclerosis
    • McCully KS, Wilson RB: Homocysteine theory of arteriosclerosis. Atherosclerosis 1975; 22:215-227
    • (1975) Atherosclerosis , vol.22 , pp. 215-227
    • McCully, K.S.1    Wilson, R.B.2
  • 22
    • 76549221821 scopus 로고
    • Homocystinuria: Studies of 20 families with 38 affected members
    • Schimke RN, McKusick VA, Huang T, Pollack AD: Homocystinuria: studies of 20 families with 38 affected members. JAMA 1965; 193:711-719
    • (1965) JAMA , vol.193 , pp. 711-719
    • Schimke, R.N.1    McKusick, V.A.2    Huang, T.3    Pollack, A.D.4
  • 24
    • 0023243363 scopus 로고
    • Psychiatric manifestations of homocystinuria due to cystathionine beta-synthase deficiency: Prevalence, natural history, and relationship to neurologic impairment and vitamin B6-responsiveness
    • Abbott MH, Folstein SE, Abbey H, Pyeritz RE: Psychiatric manifestations of homocystinuria due to cystathionine beta-synthase deficiency: prevalence, natural history, and relationship to neurologic impairment and vitamin B6-responsiveness. Am J Med Genet 1987; 26:959-969
    • (1987) Am J Med Genet , vol.26 , pp. 959-969
    • Abbott, M.H.1    Folstein, S.E.2    Abbey, H.3    Pyeritz, R.E.4
  • 25
    • 0030880665 scopus 로고    scopus 로고
    • A common polymorphism in the methylenetetrahydrofolate reductase gene, homocysteine, and ischemic cerebrovascular disease
    • Markus HS, Ali N, Swaminathan R, Sankaralingam A, Molloy J, Powell J: A common polymorphism in the methylenetetrahydrofolate reductase gene, homocysteine, and ischemic cerebrovascular disease. Stroke 1997; 28:1739-1743
    • (1997) Stroke , vol.28 , pp. 1739-1743
    • Markus, H.S.1    Ali, N.2    Swaminathan, R.3    Sankaralingam, A.4    Molloy, J.5    Powell, J.6
  • 26
    • 0344196959 scopus 로고    scopus 로고
    • Association between factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: A meta-analysis of published studies
    • Kim RJ, Becker RC: Association between factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: a meta-analysis of published studies. Am Heart J 2003; 146: 948-957
    • (2003) Am Heart J , vol.146 , pp. 948-957
    • Kim, R.J.1    Becker, R.C.2
  • 28
    • 0037967343 scopus 로고    scopus 로고
    • MTHFR gene polymorphism as a risk factor for silent brain infarcts and white matter lesions in the Japanese general population: The NILS-LSA Study
    • Kohara K, Fujisawa M, Ando F, Tabara Y, Niino N, Miki T, Shimokata H, NILS-LSA Study: MTHFR gene polymorphism as a risk factor for silent brain infarcts and white matter lesions in the Japanese general population: the NILS-LSA Study. Stroke 2003; 34:1130-1135
    • (2003) Stroke , vol.34 , pp. 1130-1135
    • Kohara, K.1    Fujisawa, M.2    Ando, F.3    Tabara, Y.4    Niino, N.5    Miki, T.6    Shimokata, H.7
  • 29
    • 1342302878 scopus 로고    scopus 로고
    • Distribution of total serum homocysteine and its association with parental history and cardiovascular risk factors at ages 12-16 years: The Third National Health and Nutrition Examination Survey
    • Gillum RF: Distribution of total serum homocysteine and its association with parental history and cardiovascular risk factors at ages 12-16 years: the Third National Health and Nutrition Examination Survey. Ann Epidemiol 2004; 14:229-233
    • (2004) Ann Epidemiol , vol.14 , pp. 229-233
    • Gillum, R.F.1
  • 30
    • 0035055560 scopus 로고    scopus 로고
    • Homozygous thermolabile variant of the methylenetetrahydrofolate reductase gene: A potential risk factor for hyperhomocysteinaemia, CVD, and stroke in childhood
    • Prengler M, Sturt N, Krywawych S, Surtees R, Liesner R, Kirkham F: Homozygous thermolabile variant of the methylenetetrahydrofolate reductase gene: a potential risk factor for hyperhomocysteinaemia, CVD, and stroke in childhood. Dev Med Child Neurol 2001; 43:220-225
    • (2001) Dev Med Child Neurol , vol.43 , pp. 220-225
    • Prengler, M.1    Sturt, N.2    Krywawych, S.3    Surtees, R.4    Liesner, R.5    Kirkham, F.6
  • 31
    • 0042919553 scopus 로고    scopus 로고
    • Multicenter Case-Control Study in China: Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a Multicenter Case-Control Study in China
    • Li Z, Sun L, Zhang H, Liao Y, Wang D, Zhao B, Zhu Z, Zhao J, Ma A, Han Y, Wang Y, Shi Y, Ye J, Hui R, Multicenter Case-Control Study in China: Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a Multicenter Case-Control Study in China. Stroke 2003; 34:2085-2090
    • (2003) Stroke , vol.34 , pp. 2085-2090
    • Li, Z.1    Sun, L.2    Zhang, H.3    Liao, Y.4    Wang, D.5    Zhao, B.6    Zhu, Z.7    Zhao, J.8    Ma, A.9    Han, Y.10    Wang, Y.11    Shi, Y.12    Ye, J.13    Hui, R.14
  • 32
    • 0344872775 scopus 로고    scopus 로고
    • Homozygous C677T mutation in the MTHFR gene as an independent risk factor for multiple small-artery occlusions
    • Choi BO, Kim NK, Kim SH, Kang MS, Lee S, Ahn JY, Kim OJ, Kim S, Oh D: Homozygous C677T mutation in the MTHFR gene as an independent risk factor for multiple small-artery occlusions. Thromb Res 2003; 111:39-44
    • (2003) Thromb Res , vol.111 , pp. 39-44
    • Choi, B.O.1    Kim, N.K.2    Kim, S.H.3    Kang, M.S.4    Lee, S.5    Ahn, J.Y.6    Kim, O.J.7    Kim, S.8    Oh, D.9
  • 33
    • 17144452539 scopus 로고    scopus 로고
    • MTHFR C677T polymorphism and its relation to ischemic stroke in the Black Sea Turkish population
    • Ucar F, Sonmez M, Ovali E, Ozmenoglu M, Karti SS, Yilmaz M, Pakdemir A: MTHFR C677T polymorphism and its relation to ischemic stroke in the Black Sea Turkish population. Am J Hematol 2004; 76:40-43
    • (2004) Am J Hematol , vol.76 , pp. 40-43
    • Ucar, F.1    Sonmez, M.2    Ovali, E.3    Ozmenoglu, M.4    Karti, S.S.5    Yilmaz, M.6    Pakdemir, A.7
  • 34
    • 0348012911 scopus 로고    scopus 로고
    • Evaluation of the modifying effects of unfavourable genotypes on classical clinical risk factors for ischaemic stroke
    • Szolnoki Z, Somogyvari F, Kondacs A, Szabo M, Fodor L, Bene J, Melegh B: Evaluation of the modifying effects of unfavourable genotypes on classical clinical risk factors for ischaemic stroke. J Neurol Neurosurg Psychiatry 2003; 74:1615-1620
    • (2003) J Neurol Neurosurg Psychiatry , vol.74 , pp. 1615-1620
    • Szolnoki, Z.1    Somogyvari, F.2    Kondacs, A.3    Szabo, M.4    Fodor, L.5    Bene, J.6    Melegh, B.7
  • 35
    • 33646235631 scopus 로고    scopus 로고
    • Neural tube defects and maternal biomarkers of folate, homocysteine, and glutathione metabolism. Birth Defects Res A Clin Mol
    • Zhao W, Mosley BS, Cleves MA, Melnyk S, James J, Hobbs CA: Neural tube defects and maternal biomarkers of folate, homocysteine, and glutathione metabolism. Birth Defects Res A Clin Mol Teratol 2006; 76:230-236
    • (2006) Teratol , vol.76 , pp. 230-236
    • Zhao, W.1    Mosley, B.S.2    Cleves, M.A.3    Melnyk, S.4    James, J.5    Hobbs, C.A.6
  • 36
    • 33646050916 scopus 로고    scopus 로고
    • Folic acid: A public-health challenge
    • Eichholzer M, Tonz O, Zimmermann R: Folic acid: a public-health challenge. Lancet 2006; 367:1352-1361
    • (2006) Lancet , vol.367 , pp. 1352-1361
    • Eichholzer, M.1    Tonz, O.2    Zimmermann, R.3
  • 38
    • 0024350346 scopus 로고
    • Plasma homocysteine, a risk factor for premature vascular disease: Plasma levels in healthy persons; during pathologic conditions and drug therapy] (Norwegian)
    • Ueland PM, Refsum H: [Plasma homocysteine, a risk factor for premature vascular disease: plasma levels in healthy persons; during pathologic conditions and drug therapy] (Norwegian). Nord Med 1989; 104:293-298
    • (1989) Nord Med , vol.104 , pp. 293-298
    • Ueland, P.M.1    Refsum, H.2
  • 39
    • 0037164375 scopus 로고    scopus 로고
    • Homocysteine and cardiovascular disease: Evidence on causality from a meta-analysis
    • Wald DS, Law M, Morris JK: Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ 2002; 325:1202
    • (2002) BMJ , vol.325 , pp. 1202
    • Wald, D.S.1    Law, M.2    Morris, J.K.3
  • 42
    • 0034056466 scopus 로고    scopus 로고
    • Association between high homocyst(e)ine and ischemic stroke due to large- and small-artery disease but not other etiologic subtypes of ischemic stroke
    • Eikelboom JW, Hankey GJ, Anand SS, Lofthouse E, Staples N, Baker RI: Association between high homocyst(e)ine and ischemic stroke due to large- and small-artery disease but not other etiologic subtypes of ischemic stroke. Stroke 2000; 31:1069-1075
    • (2000) Stroke , vol.31 , pp. 1069-1075
    • Eikelboom, J.W.1    Hankey, G.J.2    Anand, S.S.3    Lofthouse, E.4    Staples, N.5    Baker, R.I.6
  • 50
    • 1342309318 scopus 로고    scopus 로고
    • Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: The Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial
    • Toole JF, Malinow MR, Chambless LE, Spence JD, Pettigrew LC, Howard VJ, Sides EG, Wang CH, Stampfer M: Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial. JAMA 2004; 291:565-575
    • (2004) JAMA , vol.291 , pp. 565-575
    • Toole, J.F.1    Malinow, M.R.2    Chambless, L.E.3    Spence, J.D.4    Pettigrew, L.C.5    Howard, V.J.6    Sides, E.G.7    Wang, C.H.8    Stampfer, M.9
  • 51
    • 22144473356 scopus 로고    scopus 로고
    • Effect of lowering of homocysteine levels on inflammatory markers: A randomized controlled trial
    • Durga J, van Tits LJ, Schouten EG, Kok FJ, Verhoef P: Effect of lowering of homocysteine levels on inflammatory markers: a randomized controlled trial. Arch Intern Med 2005; 165:1388-1394
    • (2005) Arch Intern Med , vol.165 , pp. 1388-1394
    • Durga, J.1    van Tits, L.J.2    Schouten, E.G.3    Kok, F.J.4    Verhoef, P.5
  • 52
    • 33748349409 scopus 로고    scopus 로고
    • Significance of hyperhomocysteinemia
    • Herrmann W: Significance of hyperhomocysteinemia. Clin Lab 2006; 52:367-374
    • (2006) Clin Lab , vol.52 , pp. 367-374
    • Herrmann, W.1
  • 55
    • 33846211794 scopus 로고    scopus 로고
    • Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: A randomised, double blind, controlled trial
    • Durga J, van Boxtel MP, Schouten EG, Kok FJ, Jolles J, Katan MB, Verhoef P: Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial. Lancet 2007; 369:208-216
    • (2007) Lancet , vol.369 , pp. 208-216
    • Durga, J.1    van Boxtel, M.P.2    Schouten, E.G.3    Kok, F.J.4    Jolles, J.5    Katan, M.B.6    Verhoef, P.7
  • 56
    • 0033858407 scopus 로고    scopus 로고
    • Enhancement of the antidepressant action of fluoxetine by folic acid: A randomised, placebo controlled trial
    • Coppen A, Bailey J: Enhancement of the antidepressant action of fluoxetine by folic acid: a randomised, placebo controlled trial. J Affect Disord 2000; 60:121-130
    • (2000) J Affect Disord , vol.60 , pp. 121-130
    • Coppen, A.1    Bailey, J.2
  • 58
    • 0141609186 scopus 로고    scopus 로고
    • Poststroke depression: Prevalence, diagnosis, treatment, and disease progression
    • Robinson RG: Poststroke depression: prevalence, diagnosis, treatment, and disease progression. Biol Psychiatry 2003; 54:376-387
    • (2003) Biol Psychiatry , vol.54 , pp. 376-387
    • Robinson, R.G.1
  • 60
    • 0344824680 scopus 로고    scopus 로고
    • A reappraisal of post-stroke depression, intra- and interhemispheric lesion location using meta-analysis
    • Narushima K, Kosier JT, Robinson RG: A reappraisal of post-stroke depression, intra- and interhemispheric lesion location using meta-analysis. J Neuropsychiatry Clin Neurosci 2003; 15:422-430
    • (2003) J Neuropsychiatry Clin Neurosci , vol.15 , pp. 422-430
    • Narushima, K.1    Kosier, J.T.2    Robinson, R.G.3
  • 62
    • 0035652251 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and related factors in 600 hospitalized elderly subjects
    • Ventura P, Panini R, Verlato C, Scarpetta G, Salvioli G: Hyperhomocysteinemia and related factors in 600 hospitalized elderly subjects. Metabolism 2001; 50:1466-1471
    • (2001) Metabolism , vol.50 , pp. 1466-1471
    • Ventura, P.1    Panini, R.2    Verlato, C.3    Scarpetta, G.4    Salvioli, G.5
  • 63
    • 0027435361 scopus 로고
    • Incidence of silent cerebral infarction in patients with major depression
    • Fujikawa T, Yamawaki S, Touhouda Y: Incidence of silent cerebral infarction in patients with major depression. Stroke 1993; 24:1631-1634
    • (1993) Stroke , vol.24 , pp. 1631-1634
    • Fujikawa, T.1    Yamawaki, S.2    Touhouda, Y.3
  • 64
    • 0029894385 scopus 로고    scopus 로고
    • A magnetic resonance imaging study of white matter lesions in depression and Alzheimer's disease
    • O'Brien J, Desmond P, Ames D, Schweitzer I, Harrigan S, Tress B: A magnetic resonance imaging study of white matter lesions in depression and Alzheimer's disease. Br J Psychiatry 1996; 168:477-485
    • (1996) Br J Psychiatry , vol.168 , pp. 477-485
    • O'Brien, J.1    Desmond, P.2    Ames, D.3    Schweitzer, I.4    Harrigan, S.5    Tress, B.6
  • 67
    • 0141927311 scopus 로고    scopus 로고
    • T2-weighted image hyperintensities in major depression: Focus on the basal ganglia
    • Agid R, Levin T, Gomori JM, Lerer B, Bonne O: T2-weighted image hyperintensities in major depression: focus on the basal ganglia. Int J Neuropsychopharmacol 2003; 6:215-224
    • (2003) Int J Neuropsychopharmacol , vol.6 , pp. 215-224
    • Agid, R.1    Levin, T.2    Gomori, J.M.3    Lerer, B.4    Bonne, O.5
  • 70
    • 0037241552 scopus 로고    scopus 로고
    • Neuropathological evidence for ischemia in the white matter of the dorsolateral prefrontal cortex in late-life depression
    • Thomas AJ, Perry R, Kalaria RN, Oakley A, McMeekin W, O'Brien JT: Neuropathological evidence for ischemia in the white matter of the dorsolateral prefrontal cortex in late-life depression. Int J Geriatr Psychiatry 2003; 18:7-13
    • (2003) Int J Geriatr Psychiatry , vol.18 , pp. 7-13
    • Thomas, A.J.1    Perry, R.2    Kalaria, R.N.3    Oakley, A.4    McMeekin, W.5    O'Brien, J.T.6
  • 73
    • 0036166047 scopus 로고    scopus 로고
    • Cognitive dysfunction in recovered depressive patients with silent cerebral infarction
    • Yamashita H, Fujikawa T, Yanai I, Morinobu S, Yamawaki S: Cognitive dysfunction in recovered depressive patients with silent cerebral infarction. Neuropsychobiology 2002; 45:12-18
    • (2002) Neuropsychobiology , vol.45 , pp. 12-18
    • Yamashita, H.1    Fujikawa, T.2    Yanai, I.3    Morinobu, S.4    Yamawaki, S.5
  • 74
    • 33645675536 scopus 로고    scopus 로고
    • Focal or generalized vascular brain damage and vulnerability to depression after stroke: A 1-year prospective follow-up study
    • Aben I, Lodder J, Honig A, Lousberg R, Boreas A, Verhey F: Focal or generalized vascular brain damage and vulnerability to depression after stroke: a 1-year prospective follow-up study. Int Psychogeriatr 2006; 18:19-35
    • (2006) Int Psychogeriatr , vol.18 , pp. 19-35
    • Aben, I.1    Lodder, J.2    Honig, A.3    Lousberg, R.4    Boreas, A.5    Verhey, F.6
  • 77
    • 2942706198 scopus 로고    scopus 로고
    • White matter hyperintensities and their associations with suicidally in psychiatrically hospitalized children and adolescents
    • Ehrlich S, Noam GG, Lyoo IK, Kwon BJ, Clark MA, Renshaw PF: White matter hyperintensities and their associations with suicidally in psychiatrically hospitalized children and adolescents. J Am Acad Child Adolesc Psychiatry 2004; 43:770-776
    • (2004) J Am Acad Child Adolesc Psychiatry , vol.43 , pp. 770-776
    • Ehrlich, S.1    Noam, G.G.2    Lyoo, I.K.3    Kwon, B.J.4    Clark, M.A.5    Renshaw, P.F.6
  • 79
    • 0034822658 scopus 로고    scopus 로고
    • Depressive disorder, dysthymia, and risk of stroke: Thirteen-year follow-up from the Baltimore epidemiologic catchment area study
    • Larson SL, Owens PL, Ford D, Eaton W: Depressive disorder, dysthymia, and risk of stroke: thirteen-year follow-up from the Baltimore epidemiologic catchment area study. Stroke 2001; 32:1979-1983
    • (2001) Stroke , vol.32 , pp. 1979-1983
    • Larson, S.L.1    Owens, P.L.2    Ford, D.3    Eaton, W.4
  • 80
    • 0026177007 scopus 로고    scopus 로고
    • Tang HZ: [The changes of monoamine metabolites in CSF of patients with cerebral stroke], Zhonghua Shen Jing Jing Shen Ke Za Zhi 1991; 24:130-132, 186 (Chinese)
    • Tang HZ: [The changes of monoamine metabolites in CSF of patients with cerebral stroke], Zhonghua Shen Jing Jing Shen Ke Za Zhi 1991; 24:130-132, 186 (Chinese)
  • 83
    • 0028189416 scopus 로고
    • S-adenosyl-l-methionine (SAMe) as antidepressant: Meta-analysis of clinical studies
    • Bressa GM: S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies. Acta Neurol Scand Suppl 1994; 154:7-14
    • (1994) Acta Neurol Scand Suppl , vol.154 , pp. 7-14
    • Bressa, G.M.1
  • 84
    • 0028320572 scopus 로고
    • S-adenosylmethionine levels in psychiatric and neurological disorders: A review
    • Bottiglieri T, Hyland K: S-adenosylmethionine levels in psychiatric and neurological disorders: a review. Acta Neurol Scand Suppl 1994; 154:19-26
    • (1994) Acta Neurol Scand Suppl , vol.154 , pp. 19-26
    • Bottiglieri, T.1    Hyland, K.2
  • 85
    • 0023688477 scopus 로고
    • S-adenosylmethionine treatment of depression: A controlled clinical trial
    • Bell KM, Plon L, Bunney WE Jr, Potkin SG: S-adenosylmethionine treatment of depression: a controlled clinical trial. Am J Psychiatry 1988; 145:1110-1114
    • (1988) Am J Psychiatry , vol.145 , pp. 1110-1114
    • Bell, K.M.1    Plon, L.2    Bunney Jr, W.E.3    Potkin, S.G.4
  • 86
    • 3242663365 scopus 로고    scopus 로고
    • Folate for depressive disorders: Systematic review and meta-analysis of randomized controlled trials
    • Taylor MJ, Carney SM, Goodwin GM, Geddes JR: Folate for depressive disorders: systematic review and meta-analysis of randomized controlled trials. J Psychopharmacol 2004; 18:251-256
    • (2004) J Psychopharmacol , vol.18 , pp. 251-256
    • Taylor, M.J.1    Carney, S.M.2    Goodwin, G.M.3    Geddes, J.R.4
  • 91
    • 0037426415 scopus 로고    scopus 로고
    • Effect of L-dopa on plasma homocysteine in PD patients: Relationship to B-vitamin status
    • Miller JW, Selhub J, Nadeau MR, Thomas CA, Feldman RG, Wolf PA: Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status. Neurology 2003; 60:1125-1129
    • (2003) Neurology , vol.60 , pp. 1125-1129
    • Miller, J.W.1    Selhub, J.2    Nadeau, M.R.3    Thomas, C.A.4    Feldman, R.G.5    Wolf, P.A.6
  • 92
    • 0035987204 scopus 로고    scopus 로고
    • Catechol-O-methyltransferase (COMT)-mediated methylation metabolism of endogenous bioactive catechols and modulation by endobiotics and xenobiotics: Importance in pathophysiology and pathogenesis
    • Zhu BT: Catechol-O-methyltransferase (COMT)-mediated methylation metabolism of endogenous bioactive catechols and modulation by endobiotics and xenobiotics: importance in pathophysiology and pathogenesis. Curr Drug Metab 2002; 3:321-349
    • (2002) Curr Drug Metab , vol.3 , pp. 321-349
    • Zhu, B.T.1
  • 93
    • 0020320008 scopus 로고
    • Kinetic studies on the O-methylation of dopamine by human brain membrane-bound catechol O-methyltransferase
    • Rivett AJ, Roth JA: Kinetic studies on the O-methylation of dopamine by human brain membrane-bound catechol O-methyltransferase. Biochemistry 1982; 21:1740-1742
    • (1982) Biochemistry , vol.21 , pp. 1740-1742
    • Rivett, A.J.1    Roth, J.A.2
  • 94
    • 1842778936 scopus 로고    scopus 로고
    • Elevated S-adenosylhomocysteine in Alzheimer brain: Influence on methyltransferases and cognitive function
    • Kennedy BP, Bottiglieri T, Arning E, Ziegler MG, Hansen LA, Masliah E: Elevated S-adenosylhomocysteine in Alzheimer brain: influence on methyltransferases and cognitive function. J Neural Transm 2004; 111:547-567
    • (2004) J Neural Transm , vol.111 , pp. 547-567
    • Kennedy, B.P.1    Bottiglieri, T.2    Arning, E.3    Ziegler, M.G.4    Hansen, L.A.5    Masliah, E.6
  • 96
    • 0021086715 scopus 로고
    • Folic acid, S-adenosylmethionine and affective disorder
    • Reynolds EH, Stramentinoli G: Folic acid, S-adenosylmethionine and affective disorder. Psychol Med 1983; 13:705-710
    • (1983) Psychol Med , vol.13 , pp. 705-710
    • Reynolds, E.H.1    Stramentinoli, G.2
  • 101
    • 0038314480 scopus 로고    scopus 로고
    • Folate, vitamin B12, homocysteine, and the MTHFR 677C→T polymorphism in anxiety and depression: The Hordaland Homocysteine Study
    • Bjelland I, Tell GS, Vollset SE, Refsum H, Ueland PM: Folate, vitamin B12, homocysteine, and the MTHFR 677C→T polymorphism in anxiety and depression: the Hordaland Homocysteine Study. Arch Gen Psychiatry 2003; 60:618-626
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 618-626
    • Bjelland, I.1    Tell, G.S.2    Vollset, S.E.3    Refsum, H.4    Ueland, P.M.5
  • 103
    • 0033625099 scopus 로고    scopus 로고
    • Vitamin B(12) deficiency and depression in physically disabled older women: Epidemiologic evidence from the Women's Health and Aging Study
    • Penninx BW, Guralnik JM, Ferrucci L, Fried LP, Allen RH, Stabler SP: Vitamin B(12) deficiency and depression in physically disabled older women: epidemiologic evidence from the Women's Health and Aging Study. Am J Psychiatry 2000; 157:715-721
    • (2000) Am J Psychiatry , vol.157 , pp. 715-721
    • Penninx, B.W.1    Guralnik, J.M.2    Ferrucci, L.3    Fried, L.P.4    Allen, R.H.5    Stabler, S.P.6


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