-
1
-
-
0042332033
-
The "fuzzy logic" of the death-inducing signaling complex in lymphocytes
-
Walsh C.M., Luhrs K.A., Arechiga A.F. The "fuzzy logic" of the death-inducing signaling complex in lymphocytes. J Clin Immunol 2003, 23(5):333-353.
-
(2003)
J Clin Immunol
, vol.23
, Issue.5
, pp. 333-353
-
-
Walsh, C.M.1
Luhrs, K.A.2
Arechiga, A.F.3
-
2
-
-
84856759660
-
Many stimuli pull the necrotic trigger, an overview
-
Vanlangenakker N., Vanden Berghe T., Vandenabeele P. Many stimuli pull the necrotic trigger, an overview. Cell Death Differ 2012, 19(1):75-86.
-
(2012)
Cell Death Differ
, vol.19
, Issue.1
, pp. 75-86
-
-
Vanlangenakker, N.1
Vanden Berghe, T.2
Vandenabeele, P.3
-
3
-
-
33644840693
-
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
-
Degterev A., Huang Z., Boyce M., Li Y., Jagtap P., Mizushima N., et al. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 2005, 1(2):112-119.
-
(2005)
Nat Chem Biol
, vol.1
, Issue.2
, pp. 112-119
-
-
Degterev, A.1
Huang, Z.2
Boyce, M.3
Li, Y.4
Jagtap, P.5
Mizushima, N.6
-
4
-
-
77953543312
-
T cell intrinsic roles of autophagy in promoting adaptive immunity
-
Walsh C.M., Bell B.D. T cell intrinsic roles of autophagy in promoting adaptive immunity. Curr Opin Immunol 2010, 22(3):321-325.
-
(2010)
Curr Opin Immunol
, vol.22
, Issue.3
, pp. 321-325
-
-
Walsh, C.M.1
Bell, B.D.2
-
5
-
-
84896541259
-
True grit: programmed necrosis in antiviral host defense, inflammation, and immunogenicity
-
Mocarski E.S., Kaiser W.J., Livingston-Rosanoff D., Upton J.W., Daley-Bauer L.P. True grit: programmed necrosis in antiviral host defense, inflammation, and immunogenicity. J Immunol 2014, 192(5):2019-2026.
-
(2014)
J Immunol
, vol.192
, Issue.5
, pp. 2019-2026
-
-
Mocarski, E.S.1
Kaiser, W.J.2
Livingston-Rosanoff, D.3
Upton, J.W.4
Daley-Bauer, L.P.5
-
7
-
-
79952811804
-
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
-
Kaiser W.J., Upton J.W., Long A.B., Livingston-Rosanoff D., Daley-Bauer L.P., Hakem R., et al. RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 2011, 471(7338):368-372.
-
(2011)
Nature
, vol.471
, Issue.7338
, pp. 368-372
-
-
Kaiser, W.J.1
Upton, J.W.2
Long, A.B.3
Livingston-Rosanoff, D.4
Daley-Bauer, L.P.5
Hakem, R.6
-
8
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
Micheau O., Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 2003, 114(2):181-190.
-
(2003)
Cell
, vol.114
, Issue.2
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
9
-
-
79953240109
-
Linear ubiquitination prevents inflammation and regulates immune signalling
-
Gerlach B., Cordier S.M., Schmukle A.C., Emmerich C.H., Rieser E., Haas T.L., et al. Linear ubiquitination prevents inflammation and regulates immune signalling. Nature 2011, 471(7340):591.
-
(2011)
Nature
, vol.471
, Issue.7340
, pp. 591
-
-
Gerlach, B.1
Cordier, S.M.2
Schmukle, A.C.3
Emmerich, C.H.4
Rieser, E.5
Haas, T.L.6
-
10
-
-
44949240664
-
CIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination
-
Bertrand M.J., Milutinovic S., Dickson K.M., Ho W.C., Boudreault A., Durkin J., et al. cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol Cell 2008, 30(6):689-700.
-
(2008)
Mol Cell
, vol.30
, Issue.6
, pp. 689-700
-
-
Bertrand, M.J.1
Milutinovic, S.2
Dickson, K.M.3
Ho, W.C.4
Boudreault, A.5
Durkin, J.6
-
11
-
-
84867877809
-
NFκB and ubiquitination: partners in disarming RIPK1-mediated cell death
-
O'Donnell M.A., Ting A.T. NFκB and ubiquitination: partners in disarming RIPK1-mediated cell death. Immunol Res 2012, 54(1-3):214-226.
-
(2012)
Immunol Res
, vol.54
, Issue.1-3
, pp. 214-226
-
-
O'Donnell, M.A.1
Ting, A.T.2
-
12
-
-
0029992609
-
Suppression of TNF-alpha-induced apoptosis by NF-kappaB
-
Van Antwerp D.J., Martin S.J., Kafri T., Green D.R., Verma I.M. Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science 1996, 274(5288):787-789.
-
(1996)
Science
, vol.274
, Issue.5288
, pp. 787-789
-
-
Van Antwerp, D.J.1
Martin, S.J.2
Kafri, T.3
Green, D.R.4
Verma, I.M.5
-
13
-
-
54049155149
-
C-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor α (TNFα)-induced NF-κB activation
-
Varfolomeev E., Goncharov T., Fedorova A.V., Dynek J.N., Zobel K., Deshayes K., et al. c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor α (TNFα)-induced NF-κB activation. J Biol Chem 2008, 283(36):24295-24299.
-
(2008)
J Biol Chem
, vol.283
, Issue.36
, pp. 24295-24299
-
-
Varfolomeev, E.1
Goncharov, T.2
Fedorova, A.V.3
Dynek, J.N.4
Zobel, K.5
Deshayes, K.6
-
14
-
-
50149121101
-
Both cIAP1 and cIAP2 regulate TNFα-mediated NF-κB activation
-
Mahoney D.J., Cheung H.H., Mrad R.L., Plenchette S., Simard C., Enwere E., et al. Both cIAP1 and cIAP2 regulate TNFα-mediated NF-κB activation. Proc Natl Acad Sci U S A 2008, 105(33):11778-11783.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.33
, pp. 11778-11783
-
-
Mahoney, D.J.1
Cheung, H.H.2
Mrad, R.L.3
Plenchette, S.4
Simard, C.5
Enwere, E.6
-
15
-
-
36048999753
-
IAP antagonists induce autoubiquitination of c-IAPs, NF-κB activation, and TNFα-dependent apoptosis
-
Varfolomeev E., Blankenship J.W., Wayson S.M., Fedorova A.V., Kayagaki N., Garg P., et al. IAP antagonists induce autoubiquitination of c-IAPs, NF-κB activation, and TNFα-dependent apoptosis. Cell 2007, 131(4):669-681.
-
(2007)
Cell
, vol.131
, Issue.4
, pp. 669-681
-
-
Varfolomeev, E.1
Blankenship, J.W.2
Wayson, S.M.3
Fedorova, A.V.4
Kayagaki, N.5
Garg, P.6
-
16
-
-
36148954336
-
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
-
Vince J.E., Wong W.W., Khan N., Feltham R., Chau D., Ahmed A.U., et al. IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. Cell 2007, 131(4):682-693.
-
(2007)
Cell
, vol.131
, Issue.4
, pp. 682-693
-
-
Vince, J.E.1
Wong, W.W.2
Khan, N.3
Feltham, R.4
Chau, D.5
Ahmed, A.U.6
-
17
-
-
56349164239
-
Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK
-
Zarnegar B.J., Wang Y., Mahoney D.J., Dempsey P.W., Cheung H.H., He J., et al. Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK. Nat Immunol 2008, 9(12):1371-1378.
-
(2008)
Nat Immunol
, vol.9
, Issue.12
, pp. 1371-1378
-
-
Zarnegar, B.J.1
Wang, Y.2
Mahoney, D.J.3
Dempsey, P.W.4
Cheung, H.H.5
He, J.6
-
18
-
-
84884823502
-
CYLD deubiquitinates RIP1 in the TNFα-induced necrosome to facilitate kinase activation and programmed necrosis
-
Moquin D.M., McQuade T., Chan F.K.-M. CYLD deubiquitinates RIP1 in the TNFα-induced necrosome to facilitate kinase activation and programmed necrosis. PLoS ONE 2013, 8(10):e76841.
-
(2013)
PLoS ONE
, vol.8
, Issue.10
, pp. e76841
-
-
Moquin, D.M.1
McQuade, T.2
Chan, F.K.-M.3
-
19
-
-
57649181391
-
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
-
Hitomi J., Christofferson D.E., Ng A., Yao J., Degterev A., Xavier R.J., et al. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 2008, 135(7):1311-1323.
-
(2008)
Cell
, vol.135
, Issue.7
, pp. 1311-1323
-
-
Hitomi, J.1
Christofferson, D.E.2
Ng, A.3
Yao, J.4
Degterev, A.5
Xavier, R.J.6
-
20
-
-
43049152912
-
TNF-α induces two distinct caspase-8 activation pathways
-
Wang L., Du F., Wang X. TNF-α induces two distinct caspase-8 activation pathways. Cell 2008, 133(4):693-703.
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 693-703
-
-
Wang, L.1
Du, F.2
Wang, X.3
-
21
-
-
0042466637
-
Interdimer processing mechanism of procaspase-8 activation
-
Chang D.W., Xing Z., Capacio V.L., Peter M.E., Yang X. Interdimer processing mechanism of procaspase-8 activation. EMBO J 2003, 22(16):4132-4142.
-
(2003)
EMBO J
, vol.22
, Issue.16
, pp. 4132-4142
-
-
Chang, D.W.1
Xing, Z.2
Capacio, V.L.3
Peter, M.E.4
Yang, X.5
-
22
-
-
0033214236
-
Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
-
Lin Y., Devin A., Rodriguez Y., Liu Z.G. Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Develop 1999, 13(19):2514-2526.
-
(1999)
Genes Develop
, vol.13
, Issue.19
, pp. 2514-2526
-
-
Lin, Y.1
Devin, A.2
Rodriguez, Y.3
Liu, Z.G.4
-
23
-
-
33846922252
-
Caspase-8 prevents sustained activation of NF-kappaB in monocytes undergoing macrophagic differentiation
-
Rébé C., Cathelin S., Launay S., Filomenko R., Prévotat L., L'Ollivier C., et al. Caspase-8 prevents sustained activation of NF-kappaB in monocytes undergoing macrophagic differentiation. Blood 2007, 109(4):1442-1450.
-
(2007)
Blood
, vol.109
, Issue.4
, pp. 1442-1450
-
-
Rébé, C.1
Cathelin, S.2
Launay, S.3
Filomenko, R.4
Prévotat, L.5
L'Ollivier, C.6
-
24
-
-
34548437549
-
Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain
-
Feng S., Yang Y., Mei Y., Ma L., Zhu D.E., Hoti N., et al. Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain. Cell Signall 2007, 19(10):2056-2067.
-
(2007)
Cell Signall
, vol.19
, Issue.10
, pp. 2056-2067
-
-
Feng, S.1
Yang, Y.2
Mei, Y.3
Ma, L.4
Zhu, D.E.5
Hoti, N.6
-
25
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIPL complex inhibits RIPK3-dependent necrosis
-
Oberst A., Dillon C.P., Weinlich R., McCormick L.L., Fitzgerald P., Pop C., et al. Catalytic activity of the caspase-8-FLIPL complex inhibits RIPK3-dependent necrosis. Nature 2011, 471(7338):363-367.
-
(2011)
Nature
, vol.471
, Issue.7338
, pp. 363-367
-
-
Oberst, A.1
Dillon, C.P.2
Weinlich, R.3
McCormick, L.L.4
Fitzgerald, P.5
Pop, C.6
-
26
-
-
84856160569
-
Caspase 8 inhibits programmed necrosis by processing CYLD
-
O'Donnell M.A., Perez-Jimenez E., Oberst A., Ng A., Massoumi R., Xavier R., et al. Caspase 8 inhibits programmed necrosis by processing CYLD. Nat Cell Biol 2011, 13(12):1437.
-
(2011)
Nat Cell Biol
, vol.13
, Issue.12
, pp. 1437
-
-
O'Donnell, M.A.1
Perez-Jimenez, E.2
Oberst, A.3
Ng, A.4
Massoumi, R.5
Xavier, R.6
-
27
-
-
79960895769
-
The ripoptosome: death decision in the cytosol
-
Bertrand M.J., Vandenabeele P. The ripoptosome: death decision in the cytosol. Mol Cell 2011, 43(3):323-325.
-
(2011)
Mol Cell
, vol.43
, Issue.3
, pp. 323-325
-
-
Bertrand, M.J.1
Vandenabeele, P.2
-
28
-
-
84865296205
-
Programmed necrosis and autophagy in immune function
-
Lu J.V., Walsh C.M. Programmed necrosis and autophagy in immune function. Immunol Rev 2012, 249(1):205-217.
-
(2012)
Immunol Rev
, vol.249
, Issue.1
, pp. 205-217
-
-
Lu, J.V.1
Walsh, C.M.2
-
29
-
-
67650638892
-
RIP kinases at the crossroads of cell death and survival
-
Declercq W., Vanden Berghe T., Vandenabeele P. RIP kinases at the crossroads of cell death and survival. Cell 2009, 138(2):229-232.
-
(2009)
Cell
, vol.138
, Issue.2
, pp. 229-232
-
-
Declercq, W.1
Vanden Berghe, T.2
Vandenabeele, P.3
-
30
-
-
0037088632
-
Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3
-
Sun X., Yin J., Starovasnik M.A., Fairbrother W.J., Dixit V.M. Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3. J Biol Chem 2002, 277(11):9505-9511.
-
(2002)
J Biol Chem
, vol.277
, Issue.11
, pp. 9505-9511
-
-
Sun, X.1
Yin, J.2
Starovasnik, M.A.3
Fairbrother, W.J.4
Dixit, V.M.5
-
31
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho Y.S., Challa S., Moquin D., Genga R., Ray T.D., Guildford M., et al. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 2009, 137(6):1112-1123.
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1112-1123
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
Genga, R.4
Ray, T.D.5
Guildford, M.6
-
32
-
-
84893325471
-
Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
-
Cai Z., Jitkaew S., Zhao J., Chiang H.C., Choksi S., Liu J., et al. Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Nat Cell Biol 2013, 16(1):55-65.
-
(2013)
Nat Cell Biol
, vol.16
, Issue.1
, pp. 55-65
-
-
Cai, Z.1
Jitkaew, S.2
Zhao, J.3
Chiang, H.C.4
Choksi, S.5
Liu, J.6
-
33
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-α
-
He S., Wang L., Miao L., Wang T., Du F., Zhao L., et al. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-α. Cell 2009, 137(6):1100-1111.
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1100-1111
-
-
He, S.1
Wang, L.2
Miao, L.3
Wang, T.4
Du, F.5
Zhao, L.6
-
34
-
-
84878755914
-
Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling
-
Chen W., Zhou Z., Li L., Zhong C.Q., Zheng X., Wu X., et al. Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling. J Biol Chem 2013, 288(23):16247-16261.
-
(2013)
J Biol Chem
, vol.288
, Issue.23
, pp. 16247-16261
-
-
Chen, W.1
Zhou, Z.2
Li, L.3
Zhong, C.Q.4
Zheng, X.5
Wu, X.6
-
35
-
-
5944233768
-
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
-
Holler N., Zaru R., Micheau O., Thome M., Attinger A., Valitutti S., et al. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 2000, 1(6):489-495.
-
(2000)
Nat Immunol
, vol.1
, Issue.6
, pp. 489-495
-
-
Holler, N.1
Zaru, R.2
Micheau, O.3
Thome, M.4
Attinger, A.5
Valitutti, S.6
-
36
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches tnf-induced cell death from apoptosis to necrosis, in Science
-
Zhang D.W., Shao J., Lin J., Zhang N., Lu B.J., Lin S.C., et al. RIP3, an energy metabolism regulator that switches tnf-induced cell death from apoptosis to necrosis, in Science. Am Assoc Adv Sci 2009, 332-336.
-
(2009)
Am Assoc Adv Sci
, pp. 332-336
-
-
Zhang, D.W.1
Shao, J.2
Lin, J.3
Zhang, N.4
Lu, B.J.5
Lin, S.C.6
-
37
-
-
84869092484
-
TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation
-
Jouan-Lanhouet S., Arshad M.I., Piquet-Pellorce C., Martin-Chouly C., Le Moigne-Muller G., Van Herreweghe F., et al. TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation. Cell Death Differ 2012, 19(12):2003-2014.
-
(2012)
Cell Death Differ
, vol.19
, Issue.12
, pp. 2003-2014
-
-
Jouan-Lanhouet, S.1
Arshad, M.I.2
Piquet-Pellorce, C.3
Martin-Chouly, C.4
Le Moigne-Muller, G.5
Van Herreweghe, F.6
-
38
-
-
0034638827
-
Necrotic death pathway in Fas receptor signaling
-
Matsumura H., Simizu Y., Ohsawa Y., Kawahara A., Uchiyama Y., Nagata S. Necrotic death pathway in Fas receptor signaling. J Cell Biol 2000, 151(6):1247-1256.
-
(2000)
J Cell Biol
, vol.151
, Issue.6
, pp. 1247-1256
-
-
Matsumura, H.1
Simizu, Y.2
Ohsawa, Y.3
Kawahara, A.4
Uchiyama, Y.5
Nagata, S.6
-
39
-
-
0029054725
-
RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death
-
Stanger B. RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. Cell 1995, 81(4):513-523.
-
(1995)
Cell
, vol.81
, Issue.4
, pp. 513-523
-
-
Stanger, B.1
-
40
-
-
84903791583
-
The B-RafV600E inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury
-
Li J.X., Feng J.M., Wang Y., Li X.H., Chen X.X., Su Y., et al. The B-RafV600E inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury. Cell Death Dis 2014, 5(6):e1278.
-
(2014)
Cell Death Dis
, vol.5
, Issue.6
, pp. e1278
-
-
Li, J.X.1
Feng, J.M.2
Wang, Y.3
Li, X.H.4
Chen, X.X.5
Su, Y.6
-
41
-
-
0032695108
-
Natural adjuvants: endogenous activators of dendritic cells
-
Gallucci S., Lolkema M., Matzinger P. Natural adjuvants: endogenous activators of dendritic cells. Nat Med 1999, 5(11):1249-1255.
-
(1999)
Nat Med
, vol.5
, Issue.11
, pp. 1249-1255
-
-
Gallucci, S.1
Lolkema, M.2
Matzinger, P.3
-
42
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
-
Alexopoulou L., Holt A.C., Medzhitov R., Flavell R.A. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 2001, 413(6857):732-738.
-
(2001)
Nature
, vol.413
, Issue.6857
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
43
-
-
0034002247
-
Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide
-
Lien E., Means T.K., Heine H., Yoshimura A., Kusumoto S., Fukase K., et al. Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide. J Clin Invest 2000, 105(4):497-504.
-
(2000)
J Clin Invest
, vol.105
, Issue.4
, pp. 497-504
-
-
Lien, E.1
Means, T.K.2
Heine, H.3
Yoshimura, A.4
Kusumoto, S.5
Fukase, K.6
-
44
-
-
5444262511
-
Toll-like receptor control of the adaptive immune responses
-
Iwasaki A., Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol 2004, 5(10):987.
-
(2004)
Nat Immunol
, vol.5
, Issue.10
, pp. 987
-
-
Iwasaki, A.1
Medzhitov, R.2
-
45
-
-
78751560494
-
Pathogen recognition by the innate immune system
-
Kumar H., Kawai T., Akira S. Pathogen recognition by the innate immune system. Int Rev Immunol 2011, 30(1):16-34.
-
(2011)
Int Rev Immunol
, vol.30
, Issue.1
, pp. 16-34
-
-
Kumar, H.1
Kawai, T.2
Akira, S.3
-
46
-
-
2442642691
-
RIP1 is an essential mediator of Toll-like receptor 3--induced NF-kappaB activation
-
Meylan E., Burns K., Hofmann K., Blancheteau V., Martinon F., Kelliher M., et al. RIP1 is an essential mediator of Toll-like receptor 3--induced NF-kappaB activation. Nat Immunol 2004, 5(5):503-507.
-
(2004)
Nat Immunol
, vol.5
, Issue.5
, pp. 503-507
-
-
Meylan, E.1
Burns, K.2
Hofmann, K.3
Blancheteau, V.4
Martinon, F.5
Kelliher, M.6
-
47
-
-
27744561393
-
Rip1 mediates the Trif-dependent toll-like receptor 3-and 4-induced NF-kappaB activation but does not contribute to interferon regulatory factor 3 activation
-
Cusson-Hermance N., Khurana S., Lee T.H., Fitzgerald K.A., Kelliher M.A. Rip1 mediates the Trif-dependent toll-like receptor 3-and 4-induced NF-kappaB activation but does not contribute to interferon regulatory factor 3 activation. J Biol Chem 2005, 280(44):36560-36566.
-
(2005)
J Biol Chem
, vol.280
, Issue.44
, pp. 36560-36566
-
-
Cusson-Hermance, N.1
Khurana, S.2
Lee, T.H.3
Fitzgerald, K.A.4
Kelliher, M.A.5
-
48
-
-
84055181328
-
Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway
-
He S., Liang Y., Shao F., Wang X. Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway. Proc Natl Acad Sci 2011, 108(50):20054-20059.
-
(2011)
Proc Natl Acad Sci
, vol.108
, Issue.50
, pp. 20054-20059
-
-
He, S.1
Liang, Y.2
Shao, F.3
Wang, X.4
-
49
-
-
17144413785
-
Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif
-
Kaiser W.J., Offermann M.K. Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif. J Immunol 2005, 174(8):4942-4952.
-
(2005)
J Immunol
, vol.174
, Issue.8
, pp. 4942-4952
-
-
Kaiser, W.J.1
Offermann, M.K.2
-
50
-
-
29644433629
-
NF-κB protects macrophages from lipopolysaccharide-induced cell death
-
Ma Y., Temkin V., Liu H., Pope R.M. NF-κB protects macrophages from lipopolysaccharide-induced cell death. J Biol Chem 2005, 280(51):41827-41834.
-
(2005)
J Biol Chem
, vol.280
, Issue.51
, pp. 41827-41834
-
-
Ma, Y.1
Temkin, V.2
Liu, H.3
Pope, R.M.4
-
52
-
-
78649901091
-
Alternative cell death mechanisms in development and beyond
-
Yuan J., Kroemer G. Alternative cell death mechanisms in development and beyond. Genes Dev 2010, 24(23):2592-2602.
-
(2010)
Genes Dev
, vol.24
, Issue.23
, pp. 2592-2602
-
-
Yuan, J.1
Kroemer, G.2
-
53
-
-
84864324029
-
GRIM-19-mediated translocation of STAT3 to mitochondria is necessary for TNF-induced necroptosis
-
Shulga N., Pastorino J.G. GRIM-19-mediated translocation of STAT3 to mitochondria is necessary for TNF-induced necroptosis. J Cell Sci 2012, 125(Pt 12):2995-3003.
-
(2012)
J Cell Sci
, vol.125
, pp. 2995-3003
-
-
Shulga, N.1
Pastorino, J.G.2
-
54
-
-
79960921946
-
The ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs
-
Tenev T., Bianchi K., Darding M., Broemer M., Langlais C., Wallberg F., et al. The ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs. Mol Cell 2011, 43(3):432-448.
-
(2011)
Mol Cell
, vol.43
, Issue.3
, pp. 432-448
-
-
Tenev, T.1
Bianchi, K.2
Darding, M.3
Broemer, M.4
Langlais, C.5
Wallberg, F.6
-
55
-
-
79960922705
-
CIAPs block ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms
-
Feoktistova M., Geserick P., Kellert B., Dimitrova D.P., Langlais C., Hupe M., et al. cIAPs block ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms. Mol Cell 2011, 43(3):449-463.
-
(2011)
Mol Cell
, vol.43
, Issue.3
, pp. 449-463
-
-
Feoktistova, M.1
Geserick, P.2
Kellert, B.3
Dimitrova, D.P.4
Langlais, C.5
Hupe, M.6
-
56
-
-
0037291890
-
Insights into the regulatory mechanism for caspase-8 activation
-
Donepudi M., Mac Sweeney A., Briand C., Grütter M.G. Insights into the regulatory mechanism for caspase-8 activation. Mol Cell 2003, 11(2):543-549.
-
(2003)
Mol Cell
, vol.11
, Issue.2
, pp. 543-549
-
-
Donepudi, M.1
Mac Sweeney, A.2
Briand, C.3
Grütter, M.G.4
-
57
-
-
0031282499
-
Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells
-
Vercammen D., Vandenabeele P., Beyaert R., Declercq W., Fiers W. Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells. Cytokine 1997, 9(11):801-808.
-
(1997)
Cytokine
, vol.9
, Issue.11
, pp. 801-808
-
-
Vercammen, D.1
Vandenabeele, P.2
Beyaert, R.3
Declercq, W.4
Fiers, W.5
-
58
-
-
50049125047
-
Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses
-
Ermolaeva M.A., Michallet M.C., Papadopoulou N., Utermöhlen O., Kranidioti K., Kollias G., et al. Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses. Nat Immunol 2008, 9(9):1037-1046.
-
(2008)
Nat Immunol
, vol.9
, Issue.9
, pp. 1037-1046
-
-
Ermolaeva, M.A.1
Michallet, M.C.2
Papadopoulou, N.3
Utermöhlen, O.4
Kranidioti, K.5
Kollias, G.6
-
59
-
-
0037815277
-
Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis
-
Harper N., Hughes M., MacFarlane M., Cohen G.M. Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis. J Biol Chem 2003, 278(28):25534-25541.
-
(2003)
J Biol Chem
, vol.278
, Issue.28
, pp. 25534-25541
-
-
Harper, N.1
Hughes, M.2
MacFarlane, M.3
Cohen, G.M.4
-
60
-
-
0029858348
-
RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis
-
Ting A.T., Pimentel-Muinos F.X., Seed B. RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis. EMBO J 1996, 15(22):6189-6196.
-
(1996)
EMBO J
, vol.15
, Issue.22
, pp. 6189-6196
-
-
Ting, A.T.1
Pimentel-Muinos, F.X.2
Seed, B.3
-
61
-
-
0029949257
-
TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex
-
Hsu H., Huang J., Shu H.B., Baichwal V., Goeddel D.V., et al. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 1996, 4(4):387-396.
-
(1996)
Immunity
, vol.4
, Issue.4
, pp. 387-396
-
-
Hsu, H.1
Huang, J.2
Shu, H.B.3
Baichwal, V.4
Goeddel, D.V.5
-
62
-
-
33646034316
-
Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
-
Ea C.K., Deng L., Xia Z.P., Pineda G., Chen Z.J. Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO. Mol Cell 2006, 22(2):245-257.
-
(2006)
Mol Cell
, vol.22
, Issue.2
, pp. 245-257
-
-
Ea, C.K.1
Deng, L.2
Xia, Z.P.3
Pineda, G.4
Chen, Z.J.5
-
63
-
-
0028883850
-
Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
-
Kischkel F.C., Hellbardt S., Behrmann I., Germer M., Pawlita M., Krammer P.H., et al. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J 1995, 14(22):5579-5588.
-
(1995)
EMBO J
, vol.14
, Issue.22
, pp. 5579-5588
-
-
Kischkel, F.C.1
Hellbardt, S.2
Behrmann, I.3
Germer, M.4
Pawlita, M.5
Krammer, P.H.6
-
64
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha
-
He S., Wang L., Miao L., Wang T., Du F., Zhao L., et al. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell 2009, 137(6):1100-1111.
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1100-1111
-
-
He, S.1
Wang, L.2
Miao, L.3
Wang, T.4
Du, F.5
Zhao, L.6
-
65
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
Zhang D.W., Shao J., Lin J., Zhang N., Lu B.J., Lin S.C., et al. RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 2009, 325(5938):332-336.
-
(2009)
Science
, vol.325
, Issue.5938
, pp. 332-336
-
-
Zhang, D.W.1
Shao, J.2
Lin, J.3
Zhang, N.4
Lu, B.J.5
Lin, S.C.6
-
66
-
-
42249102086
-
Identification of RIP1 kinase as a specific cellular target of necrostatins
-
Degterev A., Hitomi J., Germscheid M., Ch'en I.L., Korkina O., Teng X., et al. Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol 2008, 4(5):313-321.
-
(2008)
Nat Chem Biol
, vol.4
, Issue.5
, pp. 313-321
-
-
Degterev, A.1
Hitomi, J.2
Germscheid, M.3
Ch'en, I.L.4
Korkina, O.5
Teng, X.6
-
67
-
-
80053087284
-
Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity
-
Lu J.V., Weist B.M., van Raam B.J., Marro B.S., Nguyen L.V., Srinivas P., et al. Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity. Proc Natl Acad Sci U S A 2011, 108(37):15312-15317.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.37
, pp. 15312-15317
-
-
Lu, J.V.1
Weist, B.M.2
van Raam, B.J.3
Marro, B.S.4
Nguyen, L.V.5
Srinivas, P.6
-
68
-
-
84862907788
-
Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
-
Sun L., Wang H., Wang Z., He S., Chen S., Liao D., et al. Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 2012, 148(1-2):213-227.
-
(2012)
Cell
, vol.148
, Issue.1-2
, pp. 213-227
-
-
Sun, L.1
Wang, H.2
Wang, Z.3
He, S.4
Chen, S.5
Liao, D.6
-
69
-
-
84884308522
-
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism
-
Murphy J.M., Czabotar P.E., Hildebrand J.M., Lucet I.S., Zhang J.G., Alvarez-Diaz S., et al. The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism. Immunity 2013, 39(3):443-453.
-
(2013)
Immunity
, vol.39
, Issue.3
, pp. 443-453
-
-
Murphy, J.M.1
Czabotar, P.E.2
Hildebrand, J.M.3
Lucet, I.S.4
Zhang, J.G.5
Alvarez-Diaz, S.6
-
70
-
-
84881184694
-
Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis
-
Wu J., Huang Z., Ren J., Zhang Z., He P., Li Y., et al. Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis. Cell Res 2013, 23(8):994-1006.
-
(2013)
Cell Res
, vol.23
, Issue.8
, pp. 994-1006
-
-
Wu, J.1
Huang, Z.2
Ren, J.3
Zhang, Z.4
He, P.5
Li, Y.6
-
71
-
-
84897088275
-
Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis
-
Newton K., Dugger D.L., Wickliffe K.E., Kapoor N., Cristina de-Almagro M., Vucic D., et al. Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis. Science 2014, 343(6177):1357-1360.
-
(2014)
Science
, vol.343
, Issue.6177
, pp. 1357-1360
-
-
Newton, K.1
Dugger, D.L.2
Wickliffe, K.E.3
Kapoor, N.4
Cristina de-Almagro, M.5
Vucic, D.6
-
72
-
-
0026713818
-
Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation
-
Schulze-Osthoff K., Bakker A.C., Vanhaesebroeck B., Beyaert R., Jacob W.A., Fiers W. Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation. J Biol Chem 1992, 267(8):5317-5323.
-
(1992)
J Biol Chem
, vol.267
, Issue.8
, pp. 5317-5323
-
-
Schulze-Osthoff, K.1
Bakker, A.C.2
Vanhaesebroeck, B.3
Beyaert, R.4
Jacob, W.A.5
Fiers, W.6
-
73
-
-
84862909353
-
The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways
-
Wang Z., Jiang H., Chen S., Du F., Wang X. The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell 2012, 148(1-2):228-243.
-
(2012)
Cell
, vol.148
, Issue.1-2
, pp. 228-243
-
-
Wang, Z.1
Jiang, H.2
Chen, S.3
Du, F.4
Wang, X.5
-
74
-
-
56249132503
-
Antigen-mediated T cell expansion regulated by parallel pathways of death
-
Ch'en I.L., Beisner D.R., Degterev A., Lynch C., Yuan J., Hoffmann A., et al. Antigen-mediated T cell expansion regulated by parallel pathways of death. Proc Natl Acad Sci U S A 2008, 105(45):17463-17468.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.45
, pp. 17463-17468
-
-
Ch'en, I.L.1
Beisner, D.R.2
Degterev, A.3
Lynch, C.4
Yuan, J.5
Hoffmann, A.6
-
75
-
-
55949083821
-
FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells
-
Bell B.D., Leverrier S., Weist B.M., Newton R.H., Arechiga A.F., Luhrs K.A., et al. FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells. Proc Natl Acad Sci U S A 2008, 105(43):16677-16682.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.43
, pp. 16677-16682
-
-
Bell, B.D.1
Leverrier, S.2
Weist, B.M.3
Newton, R.H.4
Arechiga, A.F.5
Luhrs, K.A.6
-
76
-
-
79955484750
-
Mechanisms of necroptosis in T cells
-
Ch'en I.L., Tsau J.S., Molkentin J.D., Komatsu M., Hedrick S.M. Mechanisms of necroptosis in T cells. J Exp Med 2011, 208(4):633-641.
-
(2011)
J Exp Med
, vol.208
, Issue.4
, pp. 633-641
-
-
Ch'en, I.L.1
Tsau, J.S.2
Molkentin, J.D.3
Komatsu, M.4
Hedrick, S.M.5
-
77
-
-
0037380628
-
Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity
-
Salmena L., Lemmers B., Hakem A., Matysiak-Zablocki E., Murakami K., Au P.Y., et al. Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity. Genes Dev 2003, 17(7):883-895.
-
(2003)
Genes Dev
, vol.17
, Issue.7
, pp. 883-895
-
-
Salmena, L.1
Lemmers, B.2
Hakem, A.3
Matysiak-Zablocki, E.4
Murakami, K.5
Au, P.Y.6
-
78
-
-
77955609495
-
Fas-associated death domain (FADD) is a negative regulator of T-cell receptor-mediated necroptosis
-
Osborn S.L., Diehl G., Han S.J., Xue L., Kurd N., Hsieh K., et al. Fas-associated death domain (FADD) is a negative regulator of T-cell receptor-mediated necroptosis. Proc Natl Acad Sci U S A 2010, 107(29):13034-13039.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.29
, pp. 13034-13039
-
-
Osborn, S.L.1
Diehl, G.2
Han, S.J.3
Xue, L.4
Kurd, N.5
Hsieh, K.6
-
79
-
-
0032472916
-
A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes
-
Newton K., Harris A.W., Bath M.L., Smith K.G., Strasser A. A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes. EMBO J 1998, 17(3):706-718.
-
(1998)
EMBO J
, vol.17
, Issue.3
, pp. 706-718
-
-
Newton, K.1
Harris, A.W.2
Bath, M.L.3
Smith, K.G.4
Strasser, A.5
-
80
-
-
0032055344
-
A role for FADD in T cell activation and development
-
Walsh C.M., Wen B.G., Chinnaiyan A.M., O'Rourke K., Dixit V.M., Hedrick S.M. A role for FADD in T cell activation and development. Immunity 1998, 8(4):439-449.
-
(1998)
Immunity
, vol.8
, Issue.4
, pp. 439-449
-
-
Walsh, C.M.1
Wen, B.G.2
Chinnaiyan, A.M.3
O'Rourke, K.4
Dixit, V.M.5
Hedrick, S.M.6
-
81
-
-
84872310440
-
Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase
-
Degterev A., Maki J.L., Yuan J. Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase. Cell Death Differ 2013, 20(2):366.
-
(2013)
Cell Death Differ
, vol.20
, Issue.2
, pp. 366
-
-
Degterev, A.1
Maki, J.L.2
Yuan, J.3
-
82
-
-
79952780505
-
Functional complementation between FADD and RIP1 in embryos and lymphocytes
-
Zhang H., Zhou X., McQuade T., Li J., Chan F.K., Zhang J. Functional complementation between FADD and RIP1 in embryos and lymphocytes. Nature 2011, 471(7338):373-376.
-
(2011)
Nature
, vol.471
, Issue.7338
, pp. 373-376
-
-
Zhang, H.1
Zhou, X.2
McQuade, T.3
Li, J.4
Chan, F.K.5
Zhang, J.6
-
83
-
-
84861712290
-
Survival function of the FADD-CASPASE-8-cFLIP(L) complex
-
Dillon C.P., Oberst A., Weinlich R., Janke L.J., Kang T.B., Ben-Moshe T., et al. Survival function of the FADD-CASPASE-8-cFLIP(L) complex. Cell Rep 2012, 1(5):401-407.
-
(2012)
Cell Rep
, vol.1
, Issue.5
, pp. 401-407
-
-
Dillon, C.P.1
Oberst, A.2
Weinlich, R.3
Janke, L.J.4
Kang, T.B.5
Ben-Moshe, T.6
-
84
-
-
0038205938
-
The requirements for fas-associated death domain signaling in mature T cell activation and survival
-
Beisner D.R., Chu I.H., Arechiga A.F., Hedrick S.M., Walsh C.M. The requirements for fas-associated death domain signaling in mature T cell activation and survival. J Immunol 2003, 171(1):247-256.
-
(2003)
J Immunol
, vol.171
, Issue.1
, pp. 247-256
-
-
Beisner, D.R.1
Chu, I.H.2
Arechiga, A.F.3
Hedrick, S.M.4
Walsh, C.M.5
-
85
-
-
84856231635
-
Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways
-
Mocarski E.S., Upton J.W., Kaiser W.J. Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways. Nat Rev Immunol 2012, 12(2):79-88.
-
(2012)
Nat Rev Immunol
, vol.12
, Issue.2
, pp. 79-88
-
-
Mocarski, E.S.1
Upton, J.W.2
Kaiser, W.J.3
-
86
-
-
80155206809
-
Caspase-8 inactivation in T cells increases necroptosis and suppresses autoimmunity in Bim-/- mice
-
Bohgaki T., Mozo J., Salmena L., Matysiak-Zablocki E., Bohgaki M., Sanchez O., et al. Caspase-8 inactivation in T cells increases necroptosis and suppresses autoimmunity in Bim-/- mice. J Cell Biol 2011, 195(2):277-291.
-
(2011)
J Cell Biol
, vol.195
, Issue.2
, pp. 277-291
-
-
Bohgaki, T.1
Mozo, J.2
Salmena, L.3
Matysiak-Zablocki, E.4
Bohgaki, M.5
Sanchez, O.6
-
87
-
-
0033607506
-
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
-
Bouillet P., Metcalf D., Huang D.C., Tarlinton D.M., Kay T.W., Köntgen F., et al. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 1999, 286(5445):1735-1738.
-
(1999)
Science
, vol.286
, Issue.5445
, pp. 1735-1738
-
-
Bouillet, P.1
Metcalf, D.2
Huang, D.C.3
Tarlinton, D.M.4
Kay, T.W.5
Köntgen, F.6
-
88
-
-
14944348965
-
The role of BH3-only proteins in the immune system
-
Strasser A. The role of BH3-only proteins in the immune system. Nat Rev Immunol 2005, 5(3):189-200.
-
(2005)
Nat Rev Immunol
, vol.5
, Issue.3
, pp. 189-200
-
-
Strasser, A.1
-
89
-
-
77952241062
-
Proapoptotic signalling through Toll-like receptor-3 involves TRIF-dependent activation of caspase-8 and is under the control of inhibitor of apoptosis proteins in melanoma cells
-
Weber A., Kirejczyk Z., Besch R., Potthoff S., Leverkus M., Häcker G. Proapoptotic signalling through Toll-like receptor-3 involves TRIF-dependent activation of caspase-8 and is under the control of inhibitor of apoptosis proteins in melanoma cells. Cell Death Differ 2010, 17(6):942-951.
-
(2010)
Cell Death Differ
, vol.17
, Issue.6
, pp. 942-951
-
-
Weber, A.1
Kirejczyk, Z.2
Besch, R.3
Potthoff, S.4
Leverkus, M.5
Häcker, G.6
-
90
-
-
34548687694
-
NALP inflammasomes: a central role in innate immunity
-
Martinon F., Gaide O., Pétrilli V., Mayor A., Tschopp J. NALP inflammasomes: a central role in innate immunity. Semin Immunopathol 2007, 29(3):213-229.
-
(2007)
Semin Immunopathol
, vol.29
, Issue.3
, pp. 213-229
-
-
Martinon, F.1
Gaide, O.2
Pétrilli, V.3
Mayor, A.4
Tschopp, J.5
-
91
-
-
29644433629
-
NF-kappaB protects macrophages from lipopolysaccharide-induced cell death: the role of caspase 8 and receptor-interacting protein
-
Ma Y., Temkin V., Liu H., Pope R.M. NF-kappaB protects macrophages from lipopolysaccharide-induced cell death: the role of caspase 8 and receptor-interacting protein. J Biol Chem 2005, 280(51):41827-41834.
-
(2005)
J Biol Chem
, vol.280
, Issue.51
, pp. 41827-41834
-
-
Ma, Y.1
Temkin, V.2
Liu, H.3
Pope, R.M.4
-
92
-
-
0036715377
-
Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA
-
Kalai M., Van Loo G., VandenBerghe T., Meeus A., Burm W., Saelens X., et al. Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA. Cell Death Differ 2002, 9(9):981-994.
-
(2002)
Cell Death Differ
, vol.9
, Issue.9
, pp. 981-994
-
-
Kalai, M.1
Van Loo, G.2
VandenBerghe, T.3
Meeus, A.4
Burm, W.5
Saelens, X.6
-
93
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
-
Yamamoto M., Sato S., Hemmi H., Hoshino K., Kaisho T., Sanjo H., et al. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 2003, 301(5633):640-643.
-
(2003)
Science
, vol.301
, Issue.5633
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
Sanjo, H.6
-
94
-
-
77953568668
-
Fas (CD95) induces rapid TLR4/IRAK4-dependent release of pro-inflammatory HMGB1 from macrophages
-
Wang F., Lu Z., Hawkes M., Yang H., Kain K.C., Liles W.C. Fas (CD95) induces rapid TLR4/IRAK4-dependent release of pro-inflammatory HMGB1 from macrophages. J Inflamm (Lond) 2010, 7:30.
-
(2010)
J Inflamm (Lond)
, vol.7
, pp. 30
-
-
Wang, F.1
Lu, Z.2
Hawkes, M.3
Yang, H.4
Kain, K.C.5
Liles, W.C.6
-
95
-
-
79952770123
-
RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein
-
Rajput A., Kovalenko A., Bogdanov K., Yang S.H., Kang T.B., Kim J.C., et al. RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein. Immunity 2011, 34(3):340-351.
-
(2011)
Immunity
, vol.34
, Issue.3
, pp. 340-351
-
-
Rajput, A.1
Kovalenko, A.2
Bogdanov, K.3
Yang, S.H.4
Kang, T.B.5
Kim, J.C.6
-
96
-
-
84858420051
-
DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA
-
Upton J.W., Kaiser W.J., Mocarski E.S. DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA. Cell Host Microbe 2012, 11(3):290-297.
-
(2012)
Cell Host Microbe
, vol.11
, Issue.3
, pp. 290-297
-
-
Upton, J.W.1
Kaiser, W.J.2
Mocarski, E.S.3
-
97
-
-
48349125069
-
The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation
-
Kawadler H., Gantz M.A., Riley J.L., Yang X. The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation. Mol Cell 2008, 31(3):415-421.
-
(2008)
Mol Cell
, vol.31
, Issue.3
, pp. 415-421
-
-
Kawadler, H.1
Gantz, M.A.2
Riley, J.L.3
Yang, X.4
-
98
-
-
34547111577
-
Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation
-
Misra R.S., Russell J.Q., Koenig A., Hinshaw-Makepeace J.A., Wen R., Wang D., et al. Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation. J Biol Chem 2007, 282(27):19365-19374.
-
(2007)
J Biol Chem
, vol.282
, Issue.27
, pp. 19365-19374
-
-
Misra, R.S.1
Russell, J.Q.2
Koenig, A.3
Hinshaw-Makepeace, J.A.4
Wen, R.5
Wang, D.6
-
99
-
-
38449096218
-
A Fas-associated death domain protein/caspase-8-signaling axis promotes S-phase entry and maintains S6 kinase activity in T cells responding to IL-2
-
Arechiga A.F., Bell B.D., Leverrier S., Weist B.M., Porter M., Wu Z., et al. A Fas-associated death domain protein/caspase-8-signaling axis promotes S-phase entry and maintains S6 kinase activity in T cells responding to IL-2. J Immunol 2007, 179(8):5291-5300.
-
(2007)
J Immunol
, vol.179
, Issue.8
, pp. 5291-5300
-
-
Arechiga, A.F.1
Bell, B.D.2
Leverrier, S.3
Weist, B.M.4
Porter, M.5
Wu, Z.6
-
100
-
-
84864389175
-
Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition
-
Bray K., Mathew R., Lau A., Kamphorst J.J., Fan J., Chen J., et al. Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition. PLoS ONE 2012, 7(7):e41831.
-
(2012)
PLoS ONE
, vol.7
, Issue.7
, pp. e41831
-
-
Bray, K.1
Mathew, R.2
Lau, A.3
Kamphorst, J.J.4
Fan, J.5
Chen, J.6
-
101
-
-
84872348186
-
Macroautophagy in T lymphocyte development and function
-
He M.X., McLeod I.X., Jia W., He Y.W. Macroautophagy in T lymphocyte development and function. Front Immunol 2012, 3:22.
-
(2012)
Front Immunol
, vol.3
, pp. 22
-
-
He, M.X.1
McLeod, I.X.2
Jia, W.3
He, Y.W.4
-
103
-
-
61649098378
-
Coordinate regulation of autophagy and apoptosis in T cells by death effectors: FADD or foundation
-
Bell B.D., Walsh C.M. Coordinate regulation of autophagy and apoptosis in T cells by death effectors: FADD or foundation. Autophagy 2009, 5(2):238-240.
-
(2009)
Autophagy
, vol.5
, Issue.2
, pp. 238-240
-
-
Bell, B.D.1
Walsh, C.M.2
-
104
-
-
84856160569
-
Caspase 8 inhibits programmed necrosis by processing CYLD
-
O'Donnell M.A., Perez-Jimenez E., Oberst A., Ng A., Massoumi R., Xavier R., et al. Caspase 8 inhibits programmed necrosis by processing CYLD. Nat Cell Biol 2011, 13(12):1437-1442.
-
(2011)
Nat Cell Biol
, vol.13
, Issue.12
, pp. 1437-1442
-
-
O'Donnell, M.A.1
Perez-Jimenez, E.2
Oberst, A.3
Ng, A.4
Massoumi, R.5
Xavier, R.6
-
105
-
-
0032143986
-
Targeted disruption of the mouse caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally
-
Varfolomeev E.E., Schuchmann M., Luria V., Chiannilkulchai N., Beckmann J.S., Mett I.L., et al. Targeted disruption of the mouse caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity 1998, 9(2):267-276.
-
(1998)
Immunity
, vol.9
, Issue.2
, pp. 267-276
-
-
Varfolomeev, E.E.1
Schuchmann, M.2
Luria, V.3
Chiannilkulchai, N.4
Beckmann, J.S.5
Mett, I.L.6
-
106
-
-
0032546387
-
Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1
-
Zhang J., Cado D., Chen A., Kabra N.H., Winoto A., et al. Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature 1998, 392(6673):296-300.
-
(1998)
Nature
, vol.392
, Issue.6673
, pp. 296-300
-
-
Zhang, J.1
Cado, D.2
Chen, A.3
Kabra, N.H.4
Winoto, A.5
-
107
-
-
7144263731
-
FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis
-
Yeh W.C., de la Pompa J.L., McCurrach M.E., Shu H.B., Elia A.J., Shahinian A., et al. FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science 1998, 279(5358):1954-1958.
-
(1998)
Science
, vol.279
, Issue.5358
, pp. 1954-1958
-
-
Yeh, W.C.1
de la Pompa, J.L.2
McCurrach, M.E.3
Shu, H.B.4
Elia, A.J.5
Shahinian, A.6
|