-
1
-
-
0028174061
-
Function and activation of NF-kappa B in the immune system
-
10.1146/annurev.iy.12.040194.001041 8011280 1:CAS:528:DyaK2cXivFKjurY%3D
-
Baeuerle PA, Henkel T. Function and activation of NF-kappa B in the immune system. Annu Rev Immunol. 1994;12:141-79. doi: 10.1146/annurev.iy.12. 040194.001041.
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 141-179
-
-
Baeuerle, P.A.1
Henkel, T.2
-
2
-
-
26944462054
-
The yins of T cell activation
-
10.1126/stke.2652005re1 15632417
-
Liu JO. The yins of T cell activation. Sci STKE. 2005;2005(265):re1. doi: 10.1126/stke.2652005re1.
-
(2005)
Sci STKE
, vol.2005
, Issue.265
, pp. 1
-
-
Liu, J.O.1
-
3
-
-
67650724069
-
Regulation and function of NF-kappaB transcription factors in the immune system
-
10.1146/annurev.immunol.021908.132641 19302050 1:CAS:528: DC%2BD1MXlsFSlt7o%3D
-
Vallabhapurapu S, Karin M. Regulation and function of NF-kappaB transcription factors in the immune system. Annu Rev Immunol. 2009;27:693-733. doi: 10.1146/annurev.immunol.021908.132641.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 693-733
-
-
Vallabhapurapu, S.1
Karin, M.2
-
4
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-[kappa]B activity
-
10.1146/annurev.immunol.18.1.621 10837071 1:CAS:528:DC%2BD3cXjs1Gmtro%3D
-
Karin M, Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu Rev Immunol. 2000;18:621-63. doi: 10.1146/annurev.immunol.18.1.621.
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
5
-
-
39049183044
-
Regulation and function of IKK and IKK-related kinases
-
10.1126/stke.3572006re13 17047224
-
Hacker H, Karin M. Regulation and function of IKK and IKK-related kinases. Sci STKE. 2006;2006(357):re13. doi: 10.1126/stke.3572006re13.
-
(2006)
Sci STKE
, vol.2006
, Issue.357
, pp. 13
-
-
Hacker, H.1
Karin, M.2
-
6
-
-
83855162723
-
Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-kappaB family DNA binding
-
10.1038/ni.2151 22101729
-
Siggers T, Chang AB, Teixeira A, Wong D, Williams KJ, Ahmed B, et al. Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-kappaB family DNA binding. Nat Immunol. 2011;13(1):95-102. doi: 10.1038/ni.2151.
-
(2011)
Nat Immunol
, vol.13
, Issue.1
, pp. 95-102
-
-
Siggers, T.1
Chang, A.B.2
Teixeira, A.3
Wong, D.4
Williams, K.J.5
Ahmed, B.6
-
7
-
-
80051988785
-
Hierarchies of NF-kappaB target-gene regulation
-
10.1038/ni.2070 21772277 1:CAS:528:DC%2BC3MXptV2ju7w%3D
-
Smale ST. Hierarchies of NF-kappaB target-gene regulation. Nat Immunol. 2011;12(8):689-94. doi: 10.1038/ni.2070.
-
(2011)
Nat Immunol
, vol.12
, Issue.8
, pp. 689-694
-
-
Smale, S.T.1
-
8
-
-
0033553532
-
Substrate targeting in the ubiquitin system
-
10338206 1:CAS:528:DyaK1MXjt1Oru7w%3D
-
Laney JD, Hochstrasser M. Substrate targeting in the ubiquitin system. Cell. 1999;97(4):427-30.
-
(1999)
Cell
, vol.97
, Issue.4
, pp. 427-430
-
-
Laney, J.D.1
Hochstrasser, M.2
-
9
-
-
0034691673
-
SCF(beta-TRCP) and phosphorylation dependent ubiquitination of i kappa B alpha catalyzed by Ubc3 and Ubc4
-
10.1038/sj.onc.1203647 10918611 1:CAS:528:DC%2BD3cXlslyhtrw%3D
-
Strack P, Caligiuri M, Pelletier M, Boisclair M, Theodoras A, Beer-Romero P, et al. SCF(beta-TRCP) and phosphorylation dependent ubiquitination of I kappa B alpha catalyzed by Ubc3 and Ubc4. Oncogene. 2000;19(31):3529-36. doi: 10.1038/sj.onc.1203647.
-
(2000)
Oncogene
, vol.19
, Issue.31
, pp. 3529-3536
-
-
Strack, P.1
Caligiuri, M.2
Pelletier, M.3
Boisclair, M.4
Theodoras, A.5
Beer-Romero, P.6
-
10
-
-
17944401842
-
Identification of the receptor component of the IkappaBalpha-ubiquitin ligase
-
10.1038/25159 9859996 1:CAS:528:DyaK1cXotVWnt78%3D
-
Yaron A, Hatzubai A, Davis M, Lavon I, Amit S, Manning AM, et al. Identification of the receptor component of the IkappaBalpha-ubiquitin ligase. Nature. 1998;396(6711):590-4. doi: 10.1038/25159.
-
(1998)
Nature
, vol.396
, Issue.6711
, pp. 590-594
-
-
Yaron, A.1
Hatzubai, A.2
Davis, M.3
Lavon, I.4
Amit, S.5
Manning, A.M.6
-
11
-
-
0029992609
-
Suppression of TNF-alpha-induced apoptosis by NF-kappaB
-
8864120
-
Van Antwerp DJ, Martin SJ, Kafri T, Green DR, Verma IM. Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science. 1996;274(5288):787-9.
-
(1996)
Science
, vol.274
, Issue.5288
, pp. 787-789
-
-
Van Antwerp, D.J.1
Martin, S.J.2
Kafri, T.3
Green, D.R.4
Verma, I.M.5
-
12
-
-
0029858387
-
TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
-
8864119 1:CAS:528:DyaK28XmsFOhu7Y%3D
-
Wang CY, Mayo MW, Baldwin AS Jr. TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. Science. 1996;274(5288):784-7.
-
(1996)
Science
, vol.274
, Issue.5288
, pp. 784-787
-
-
Wang, C.Y.1
Mayo, M.W.2
Baldwin Jr., A.S.3
-
13
-
-
79955620198
-
Constructing and decoding unconventional ubiquitin chains
-
10.1038/nsmb.2066 21540891 1:CAS:528:DC%2BC3MXlsFKnur0%3D
-
Behrends C, Harper JW. Constructing and decoding unconventional ubiquitin chains. Nat Struct Mol Biol. 2011;18(5):520-8. doi: 10.1038/nsmb.2066.
-
(2011)
Nat Struct Mol Biol
, vol.18
, Issue.5
, pp. 520-528
-
-
Behrends, C.1
Harper, J.W.2
-
14
-
-
62549155321
-
Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation
-
10.1016/j.cell.2009.03.007 19303852 1:CAS:528:DC%2BD1MXltFSnt78%3D
-
Rahighi S, Ikeda F, Kawasaki M, Akutsu M, Suzuki N, Kato R, et al. Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation. Cell. 2009;136(6):1098-109. doi: 10.1016/j.cell.2009.03. 007.
-
(2009)
Cell
, vol.136
, Issue.6
, pp. 1098-1109
-
-
Rahighi, S.1
Ikeda, F.2
Kawasaki, M.3
Akutsu, M.4
Suzuki, N.5
Kato, R.6
-
15
-
-
59649103156
-
Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation
-
10.1038/ncb1821 19136968 1:CAS:528:DC%2BD1MXht1Oqt7k%3D
-
Tokunaga F, Sakata S, Saeki Y, Satomi Y, Kirisako T, Kamei K, et al. Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation. Nat Cell Biol. 2009;11(2):123-32. doi: 10.1038/ncb1821.
-
(2009)
Nat Cell Biol
, vol.11
, Issue.2
, pp. 123-132
-
-
Tokunaga, F.1
Sakata, S.2
Saeki, Y.3
Satomi, Y.4
Kirisako, T.5
Kamei, K.6
-
16
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
12887920 1:CAS:528:DC%2BD3sXlvFCgu7Y%3D
-
Micheau O, Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell. 2003;114(2):181-90.
-
(2003)
Cell
, vol.114
, Issue.2
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
17
-
-
0029858348
-
RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis
-
8947041 1:CAS:528:DyaK28XnsFKrtLg%3D
-
Ting AT, Pimentel-Muinos FX, Seed B. RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis. EMBO J. 1996;15(22):6189-96.
-
(1996)
EMBO J
, vol.15
, Issue.22
, pp. 6189-6196
-
-
Ting, A.T.1
Pimentel-Muinos, F.X.2
Seed, B.3
-
18
-
-
0032033132
-
The death domain kinase RIP mediates the TNF-induced NF-kappaB signal
-
9529147 1:CAS:528:DyaK1cXitFGgsLk%3D
-
Kelliher MA, Grimm S, Ishida Y, Kuo F, Stanger BZ, Leder P. The death domain kinase RIP mediates the TNF-induced NF-kappaB signal. Immunity. 1998;8(3):297-303.
-
(1998)
Immunity
, vol.8
, Issue.3
, pp. 297-303
-
-
Kelliher, M.A.1
Grimm, S.2
Ishida, Y.3
Kuo, F.4
Stanger, B.Z.5
Leder, P.6
-
19
-
-
4043136609
-
The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2
-
10.1074/jbc.M404206200 15175328 1:CAS:528:DC%2BD2cXmtFOisb4%3D
-
Lee TH, Shank J, Cusson N, Kelliher MA. The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2. J Biol Chem. 2004;279(32):33185-91. doi: 10.1074/jbc.M404206200.
-
(2004)
J Biol Chem
, vol.279
, Issue.32
, pp. 33185-33191
-
-
Lee, T.H.1
Shank, J.2
Cusson, N.3
Kelliher, M.A.4
-
20
-
-
0031463025
-
Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice
-
9390694 1:CAS:528:DyaK2sXnvVWnu7s%3D
-
Yeh WC, Shahinian A, Speiser D, Kraunus J, Billia F, Wakeham A, et al. Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice. Immunity. 1997;7(5):715-25.
-
(1997)
Immunity
, vol.7
, Issue.5
, pp. 715-725
-
-
Yeh, W.C.1
Shahinian, A.2
Speiser, D.3
Kraunus, J.4
Billia, F.5
Wakeham, A.6
-
21
-
-
3943054838
-
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling
-
10.1038/nature02794 15258597 1:CAS:528:DC%2BD2cXmt1Gisb8%3D
-
Wertz IE, O'Rourke KM, Zhou H, Eby M, Aravind L, Seshagiri S, et al. De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling. Nature. 2004;430(7000):694-9. doi: 10.1038/nature02794.
-
(2004)
Nature
, vol.430
, Issue.7000
, pp. 694-699
-
-
Wertz, I.E.1
O'Rourke, K.M.2
Zhou, H.3
Eby, M.4
Aravind, L.5
Seshagiri, S.6
-
22
-
-
0036337748
-
A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells
-
12167698 1:CAS:528:DC%2BD38Xmt1entrw%3D
-
He KL, Ting AT. A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells. Mol Cell Biol. 2002;22(17):6034-45.
-
(2002)
Mol Cell Biol
, vol.22
, Issue.17
, pp. 6034-6045
-
-
He, K.L.1
Ting, A.T.2
-
23
-
-
33744951304
-
Ubiquitination of RIP is required for tumor necrosis factor alpha-induced NF-kappaB activation
-
10.1074/jbc.M600620200 16543241 1:CAS:528:DC%2BD28Xkt1ymtLc%3D
-
Li H, Kobayashi M, Blonska M, You Y, Lin X. Ubiquitination of RIP is required for tumor necrosis factor alpha-induced NF-kappaB activation. J Biol Chem. 2006;281(19):13636-43. doi: 10.1074/jbc.M600620200.
-
(2006)
J Biol Chem
, vol.281
, Issue.19
, pp. 13636-13643
-
-
Li, H.1
Kobayashi, M.2
Blonska, M.3
You, Y.4
Lin, X.5
-
24
-
-
33646034316
-
Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
-
10.1016/j.molcel.2006.03.026 16603398 1:CAS:528:DC%2BD28Xkt1Gmtb8%3D
-
Ea CK, Deng L, Xia ZP, Pineda G, Chen ZJ. Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO. Mol Cell. 2006;22(2):245-57. doi: 10.1016/j.molcel.2006.03.026.
-
(2006)
Mol Cell
, vol.22
, Issue.2
, pp. 245-257
-
-
Ea, C.K.1
Deng, L.2
Xia, Z.P.3
Pineda, G.4
Chen, Z.J.5
-
25
-
-
33645703930
-
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]
-
10.1038/ncb1384 16547522 1:CAS:528:DC%2BD28Xjt12qs7o%3D
-
Wu CJ, Conze DB, Li T, Srinivasula SM, Ashwell JD. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]. Nat Cell Biol. 2006;8(4):398-406. doi: 10.1038/ncb1384.
-
(2006)
Nat Cell Biol
, vol.8
, Issue.4
, pp. 398-406
-
-
Wu, C.J.1
Conze, D.B.2
Li, T.3
Srinivasula, S.M.4
Ashwell, J.D.5
-
26
-
-
4344712350
-
TAB 2 and TAB 3 activate the NF-kappaB pathway through binding to polyubiquitin chains
-
10.1016/j.molcel.2004.08.008 15327770 1:CAS:528:DC%2BD2cXns1ynurY%3D
-
Kanayama A, Seth RB, Sun L, Ea CK, Hong M, Shaito A, et al. TAB 2 and TAB 3 activate the NF-kappaB pathway through binding to polyubiquitin chains. Mol Cell. 2004;15(4):535-48. doi: 10.1016/j.molcel.2004.08.008.
-
(2004)
Mol Cell
, vol.15
, Issue.4
, pp. 535-548
-
-
Kanayama, A.1
Seth, R.B.2
Sun, L.3
Ea, C.K.4
Hong, M.5
Shaito, A.6
-
27
-
-
49549117842
-
Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies
-
10.1016/j.cell.2008.07.039 18724939 1:CAS:528:DC%2BD1cXhtVGqtrbK
-
Newton K, Matsumoto ML, Wertz IE, Kirkpatrick DS, Lill JR, Tan J, et al. Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies. Cell. 2008;134(4):668-78. doi: 10.1016/j.cell.2008.07.039.
-
(2008)
Cell
, vol.134
, Issue.4
, pp. 668-678
-
-
Newton, K.1
Matsumoto, M.L.2
Wertz, I.E.3
Kirkpatrick, D.S.4
Lill, J.R.5
Tan, J.6
-
28
-
-
40749139505
-
Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase
-
10.1128/MCB.02380-06 18180283 1:CAS:528:DC%2BD1cXivVajtb8%3D
-
Windheim M, Stafford M, Peggie M, Cohen P. Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase. Mol Cell Biol. 2008;28(5):1783-91. doi: 10.1128/MCB.02380-06.
-
(2008)
Mol Cell Biol
, vol.28
, Issue.5
, pp. 1783-1791
-
-
Windheim, M.1
Stafford, M.2
Peggie, M.3
Cohen, P.4
-
29
-
-
36249008032
-
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation
-
10.1038/sj.emboj.7601897 17948050 1:CAS:528:DC%2BD2sXht12gtbbK
-
Oeckinghaus A, Wegener E, Welteke V, Ferch U, Arslan SC, Ruland J, et al. Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation. EMBO J. 2007;26(22):4634-45. doi: 10.1038/sj.emboj.7601897.
-
(2007)
EMBO J
, vol.26
, Issue.22
, pp. 4634-4645
-
-
Oeckinghaus, A.1
Wegener, E.2
Welteke, V.3
Ferch, U.4
Arslan, S.C.5
Ruland, J.6
-
30
-
-
42949098959
-
NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation
-
10.1073/pnas.0712313105 18287044 1:CAS:528:DC%2BD1cXjtVSitrw%3D
-
Wu CJ, Ashwell JD. NEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activation. Proc Natl Acad Sci USA. 2008;105(8):3023-8. doi: 10.1073/pnas.0712313105.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.8
, pp. 3023-3028
-
-
Wu, C.J.1
Ashwell, J.D.2
-
31
-
-
0041967294
-
Essential role for IKKgamma/NEMO in TCR-induced IL-2 expression in Jurkat T cells
-
10.1002/eji.200323650 12884855 1:CAS:528:DC%2BD3sXlslWlsb8%3D
-
He KL, Ting AT. Essential role for IKKgamma/NEMO in TCR-induced IL-2 expression in Jurkat T cells. Eur J Immunol. 2003;33(7):1917-24. doi: 10.1002/eji.200323650.
-
(2003)
Eur J Immunol
, vol.33
, Issue.7
, pp. 1917-1924
-
-
He, K.L.1
Ting, A.T.2
-
32
-
-
77949332322
-
The RING domain of TRAF2 plays an essential role in the inhibition of TNFalpha-induced cell death but not in the activation of NF-kappaB
-
10.1016/j.jmb.2010.01.008 20064526 1:CAS:528:DC%2BC3cXhs1ymu7Y%3D
-
Zhang L, Blackwell K, Shi Z, Habelhah H. The RING domain of TRAF2 plays an essential role in the inhibition of TNFalpha-induced cell death but not in the activation of NF-kappaB. J Mol Biol. 2010;396(3):528-39. doi: 10.1016/j.jmb.2010.01.008.
-
(2010)
J Mol Biol
, vol.396
, Issue.3
, pp. 528-539
-
-
Zhang, L.1
Blackwell, K.2
Shi, Z.3
Habelhah, H.4
-
33
-
-
71149105333
-
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction
-
10.1016/j.molcel.2009.10.013 20005846 1:CAS:528:DC%2BC3cXht1Cjsr4%3D
-
Haas TL, Emmerich CH, Gerlach B, Schmukle AC, Cordier SM, Rieser E, et al. Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction. Mol Cell. 2009;36(5):831-44. doi: 10.1016/j.molcel.2009.10.013.
-
(2009)
Mol Cell
, vol.36
, Issue.5
, pp. 831-844
-
-
Haas, T.L.1
Emmerich, C.H.2
Gerlach, B.3
Schmukle, A.C.4
Cordier, S.M.5
Rieser, E.6
-
34
-
-
44949240664
-
CIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination
-
10.1016/j.molcel.2008.05.014 18570872 1:CAS:528:DC%2BD1cXnvFWnt74%3D
-
Bertrand MJ, Milutinovic S, Dickson KM, Ho WC, Boudreault A, Durkin J, et al. cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol Cell. 2008;30(6):689-700. doi: 10.1016/j.molcel.2008.05.014.
-
(2008)
Mol Cell
, vol.30
, Issue.6
, pp. 689-700
-
-
Bertrand, M.J.1
Milutinovic, S.2
Dickson, K.M.3
Ho, W.C.4
Boudreault, A.5
Durkin, J.6
-
35
-
-
2442559290
-
Receptor interacting protein is ubiquitinated by cellular inhibitor of apoptosis proteins (c-IAP1 and c-IAP2) in vitro
-
10.1016/j.febslet.2004.04.021 15147886 1:CAS:528:DC%2BD2cXktVOksrw%3D
-
Park SM, Yoon JB, Lee TH. Receptor interacting protein is ubiquitinated by cellular inhibitor of apoptosis proteins (c-IAP1 and c-IAP2) in vitro. FEBS Lett. 2004;566(1-3):151-6. doi: 10.1016/j.febslet.2004.04.021.
-
(2004)
FEBS Lett
, vol.566
, Issue.1-3
, pp. 151-156
-
-
Park, S.M.1
Yoon, J.B.2
Lee, T.H.3
-
36
-
-
72149117664
-
TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}B and to prevent tnf-induced apoptosis
-
10.1074/jbc.M109.072256 19815541 1:CAS:528:DC%2BD1MXhsFCqu7%2FI
-
Vince JE, Pantaki D, Feltham R, Mace PD, Cordier SM, Schmukle AC, et al. TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}B and to prevent tnf-induced apoptosis. J Biol Chem. 2009;284(51):35906-15. doi: 10.1074/jbc.M109.072256.
-
(2009)
J Biol Chem
, vol.284
, Issue.51
, pp. 35906-35915
-
-
Vince, J.E.1
Pantaki, D.2
Feltham, R.3
MacE, P.D.4
Cordier, S.M.5
Schmukle, A.C.6
-
37
-
-
77953923379
-
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
-
10.1038/nature09128 20577214 1:CAS:528:DC%2BC3cXnvFSgs7s%3D
-
Alvarez SE, Harikumar KB, Hait NC, Allegood J, Strub GM, Kim EY, et al. Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Nature. 2010;465(7301):1084-8. doi: 10.1038/nature09128.
-
(2010)
Nature
, vol.465
, Issue.7301
, pp. 1084-1088
-
-
Alvarez, S.E.1
Harikumar, K.B.2
Hait, N.C.3
Allegood, J.4
Strub, G.M.5
Kim, E.Y.6
-
38
-
-
29444453188
-
The anti-death machinery in IKK/NF-kappaB signaling
-
10.1007/s10875-005-8217-6 16380818 1:CAS:528:DC%2BD2MXhtlGhsb%2FL
-
Luo JL, Kamata H, Karin M. The anti-death machinery in IKK/NF-kappaB signaling. J Clin Immunol. 2005;25(6):541-50. doi: 10.1007/s10875-005-8217-6.
-
(2005)
J Clin Immunol
, vol.25
, Issue.6
, pp. 541-550
-
-
Luo, J.L.1
Kamata, H.2
Karin, M.3
-
39
-
-
0034743199
-
NF-kappaB signals induce the expression of c-FLIP
-
10.1128/MCB.21.16.5299-5305.2001 11463813 1:CAS:528:DC%2BD3MXlslOjt7o%3D
-
Micheau O, Lens S, Gaide O, Alevizopoulos K, Tschopp J. NF-kappaB signals induce the expression of c-FLIP. Mol Cell Biol. 2001;21(16):5299-305. doi: 10.1128/MCB.21.16.5299-5305.2001.
-
(2001)
Mol Cell Biol
, vol.21
, Issue.16
, pp. 5299-5305
-
-
Micheau, O.1
Lens, S.2
Gaide, O.3
Alevizopoulos, K.4
Tschopp, J.5
-
40
-
-
0029054725
-
RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death
-
7538908 1:CAS:528:DyaK2MXlvVGgtbc%3D
-
Stanger BZ, Leder P, Lee TH, Kim E, Seed B. RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. Cell. 1995;81(4):513-23.
-
(1995)
Cell
, vol.81
, Issue.4
, pp. 513-523
-
-
Stanger, B.Z.1
Leder, P.2
Lee, T.H.3
Kim, E.4
Seed, B.5
-
41
-
-
0036645407
-
The death domain kinase RIP protects thymocytes from tumor necrosis factor receptor type 2-induced cell death
-
12093867 1:CAS:528:DC%2BD38Xlt1WhtL0%3D
-
Cusson N, Oikemus S, Kilpatrick ED, Cunningham L, Kelliher M. The death domain kinase RIP protects thymocytes from tumor necrosis factor receptor type 2-induced cell death. J Exp Med. 2002;196(1):15-26.
-
(2002)
J Exp Med
, vol.196
, Issue.1
, pp. 15-26
-
-
Cusson, N.1
Oikemus, S.2
Kilpatrick, E.D.3
Cunningham, L.4
Kelliher, M.5
-
42
-
-
0033965946
-
A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes
-
10.1002/1521-4141(200002)30:2<652: AID-IMMU652>3.0.CO;2-L 10671223 1:CAS:528:DC%2BD3cXhtF2qtrY%3D
-
Chan FK, Lenardo MJ. A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes. Eur J Immunol. 2000;30(2):652-60. doi: 10.1002/1521-4141(200002)30:2<652::AID-IMMU652>3.0.CO;2-L.
-
(2000)
Eur J Immunol
, vol.30
, Issue.2
, pp. 652-660
-
-
Chan, F.K.1
Lenardo, M.J.2
-
43
-
-
0033452005
-
Regulated commitment of TNF receptor signaling: A molecular switch for death or activation
-
10626900 1:CAS:528:DC%2BD3cXkt1Shtw%3D%3D
-
Pimentel-Muinos FX, Seed B. Regulated commitment of TNF receptor signaling: a molecular switch for death or activation. Immunity. 1999;11(6):783-93.
-
(1999)
Immunity
, vol.11
, Issue.6
, pp. 783-793
-
-
Pimentel-Muinos, F.X.1
Seed, B.2
-
44
-
-
0032553419
-
Nuclear factor kB-independent cytoprotective pathways originating at tumor necrosis factor receptor-associated factor 2
-
9813034 1:CAS:528:DyaK1cXns1egu7g%3D
-
Natoli G, Costanzo A, Guido F, Moretti F, Bernardo A, Burgio VL, et al. Nuclear factor kB-independent cytoprotective pathways originating at tumor necrosis factor receptor-associated factor 2. J Biol Chem. 1998;273(47):31262- 72.
-
(1998)
J Biol Chem
, vol.273
, Issue.47
, pp. 31262-31272
-
-
Natoli, G.1
Costanzo, A.2
Guido, F.3
Moretti, F.4
Bernardo, A.5
Burgio, V.L.6
-
45
-
-
0005231498
-
Stimulus-dependent synergism of the antiapoptotic tumor necrosis factor receptor-associated factor 2 (TRAF2) and nuclear factor kappaB pathways
-
9763618 1:CAS:528:DyaK1cXmsFals7o%3D
-
Lee SY, Kaufman DR, Mora AL, Santana A, Boothby M, Choi Y. Stimulus-dependent synergism of the antiapoptotic tumor necrosis factor receptor-associated factor 2 (TRAF2) and nuclear factor kappaB pathways. J Exp Med. 1998;188(7):1381-4.
-
(1998)
J Exp Med
, vol.188
, Issue.7
, pp. 1381-1384
-
-
Lee, S.Y.1
Kaufman, D.R.2
Mora, A.L.3
Santana, A.4
Boothby, M.5
Choi, Y.6
-
46
-
-
0032508414
-
NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
-
9733516 1:CAS:528:DyaK1cXmtVWhurk%3D
-
Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science. 1998;281(5383):1680-3.
-
(1998)
Science
, vol.281
, Issue.5383
, pp. 1680-1683
-
-
Wang, C.Y.1
Mayo, M.W.2
Korneluk, R.G.3
Goeddel, D.V.4
Baldwin Jr., A.S.5
-
47
-
-
0033662341
-
Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development
-
10894163 1:CAS:528:DC%2BD3cXkslagtbo%3D
-
Yeh WC, Itie A, Elia AJ, Ng M, Shu HB, Wakeham A, et al. Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development. Immunity. 2000;12(6):633-42.
-
(2000)
Immunity
, vol.12
, Issue.6
, pp. 633-642
-
-
Yeh, W.C.1
Itie, A.2
Elia, A.J.3
Ng, M.4
Shu, H.B.5
Wakeham, A.6
-
48
-
-
0026699666
-
Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements
-
1381359 1:CAS:528:DyaK38XkvVCmurw%3D
-
Krikos A, Laherty CD, Dixit VM. Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements. J Biol Chem. 1992;267(25):17971-6.
-
(1992)
J Biol Chem
, vol.267
, Issue.25
, pp. 17971-17976
-
-
Krikos, A.1
Laherty, C.D.2
Dixit, V.M.3
-
49
-
-
0034730713
-
Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice
-
11009421 1:CAS:528:DC%2BD3cXmvF2qtbY%3D
-
Lee EG, Boone DL, Chai S, Libby SL, Chien M, Lodolce JP, et al. Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice. Science. 2000;289(5488):2350-4.
-
(2000)
Science
, vol.289
, Issue.5488
, pp. 2350-2354
-
-
Lee, E.G.1
Boone, D.L.2
Chai, S.3
Libby, S.L.4
Chien, M.5
Lodolce, J.P.6
-
50
-
-
0027282044
-
Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
-
8358789 1:CAS:528:DyaK3sXmsVans7g%3D
-
Boise LH, Gonzalez-Garcia M, Postema CE, Ding L, Lindsten T, Turka LA, et al. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell. 1993;74(4):597-608.
-
(1993)
Cell
, vol.74
, Issue.4
, pp. 597-608
-
-
Boise, L.H.1
Gonzalez-Garcia, M.2
Postema, C.E.3
Ding, L.4
Lindsten, T.5
Turka, L.A.6
-
51
-
-
0033621956
-
The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L)
-
10733571
-
Chen C, Edelstein LC, Gelinas C. The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L). Mol Cell Biol. 2000;20(8):2687-95.
-
(2000)
Mol Cell Biol
, vol.20
, Issue.8
, pp. 2687-2695
-
-
Chen, C.1
Edelstein, L.C.2
Gelinas, C.3
-
52
-
-
0028922885
-
Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice
-
7878471 1:CAS:528:DyaK2MXktlCltLk%3D
-
Motoyama N, Wang F, Roth KA, Sawa H, Nakayama K, Negishi I, et al. Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice. Science. 1995;267(5203):1506-10.
-
(1995)
Science
, vol.267
, Issue.5203
, pp. 1506-1510
-
-
Motoyama, N.1
Wang, F.2
Roth, K.A.3
Sawa, H.4
Nakayama, K.5
Negishi, I.6
-
53
-
-
0031693206
-
Apoptotic, non-apoptotic, and anti-apoptotic pathways of tumor necrosis factor signalling
-
9776301 1:CAS:528:DyaK1cXmsVyrurc%3D
-
Natoli G, Costanzo A, Guido F, Moretti F, Levrero M. Apoptotic, non-apoptotic, and anti-apoptotic pathways of tumor necrosis factor signalling. Biochem Pharmacol. 1998;56(8):915-20.
-
(1998)
Biochem Pharmacol
, vol.56
, Issue.8
, pp. 915-920
-
-
Natoli, G.1
Costanzo, A.2
Guido, F.3
Moretti, F.4
Levrero, M.5
-
54
-
-
0037149542
-
TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2
-
10.1038/416345a 11907583
-
Li X, Yang Y, Ashwell JD. TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2. Nature. 2002;416(6878):345-7. doi: 10.1038/416345a.
-
(2002)
Nature
, vol.416
, Issue.6878
, pp. 345-347
-
-
Li, X.1
Yang, Y.2
Ashwell, J.D.3
-
55
-
-
0036629347
-
Apoptotic crosstalk of TNF receptors: TNF-R2-induces depletion of TRAF2 and IAP proteins and accelerates TNF-R1-dependent activation of caspase-8
-
12077366 1:CAS:528:DC%2BD38XlsFCrtLc%3D
-
Fotin-Mleczek M, Henkler F, Samel D, Reichwein M, Hausser A, Parmryd I, et al. Apoptotic crosstalk of TNF receptors: TNF-R2-induces depletion of TRAF2 and IAP proteins and accelerates TNF-R1-dependent activation of caspase-8. J Cell Sci. 2002;115(Pt 13):2757-70.
-
(2002)
J Cell Sci
, vol.115
, Issue.PART 13
, pp. 2757-2770
-
-
Fotin-Mleczek, M.1
Henkler, F.2
Samel, D.3
Reichwein, M.4
Hausser, A.5
Parmryd, I.6
-
56
-
-
33847251527
-
Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling
-
10.1016/j.cub.2007.01.027 17306544
-
O'Donnell MA, Legarda D, Skountzos P, Yeh WC, Ting AT. Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling. Curr Biol. 2007;17(5):418-24. doi: 10.1016/j.cub.2007.01.027.
-
(2007)
Curr Biol
, vol.17
, Issue.5
, pp. 418-424
-
-
O'Donnell, M.A.1
Legarda, D.2
Skountzos, P.3
Yeh, W.C.4
Ting, A.T.5
-
57
-
-
43049152912
-
TNF-alpha induces two distinct caspase-8 activation pathways
-
10.1016/j.cell.2008.03.036 18485876 1:CAS:528:DC%2BD1cXmsVOru78%3D
-
Wang L, Du F, Wang X. TNF-alpha induces two distinct caspase-8 activation pathways. Cell. 2008;133(4):693-703. doi: 10.1016/j.cell.2008.03.036.
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 693-703
-
-
Wang, L.1
Du, F.2
Wang, X.3
-
58
-
-
69049092633
-
NEMO/IKKgamma regulates an early NF-kappaB-independent cell-death checkpoint during TNF signaling
-
10.1038/cdd.2009.41 19373245 1:CAS:528:DC%2BD1MXhtVamur%2FP
-
Legarda-Addison D, Hase H, O'Donnell MA, Ting AT. NEMO/IKKgamma regulates an early NF-kappaB-independent cell-death checkpoint during TNF signaling. Cell Death Differ. 2009;16(9):1279-88. doi: 10.1038/cdd.2009.41.
-
(2009)
Cell Death Differ
, vol.16
, Issue.9
, pp. 1279-1288
-
-
Legarda-Addison, D.1
Hase, H.2
O'Donnell, M.A.3
Ting, A.T.4
-
59
-
-
56249132503
-
Antigen-mediated T cell expansion regulated by parallel pathways of death
-
10.1073/pnas.0808043105 18981423
-
Ch'en IL, Beisner DR, Degterev A, Lynch C, Yuan J, Hoffmann A, et al. Antigen-mediated T cell expansion regulated by parallel pathways of death. Proc Natl Acad Sci USA. 2008;105(45):17463-8. doi: 10.1073/pnas.0808043105.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.45
, pp. 17463-17468
-
-
Ch'En, I.L.1
Beisner, D.R.2
Degterev, A.3
Lynch, C.4
Yuan, J.5
Hoffmann, A.6
-
61
-
-
80053087284
-
Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity
-
10.1073/pnas.1102779108 21876153 1:CAS:528:DC%2BC3MXht1Gqt7zJ
-
Lu JV, Weist BM, van Raam BJ, Marro BS, Nguyen LV, Srinivas P, et al. Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity. Proc Natl Acad Sci USA. 2011;108(37):15312-7. doi: 10.1073/pnas.1102779108.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.37
, pp. 15312-15317
-
-
Lu, J.V.1
Weist, B.M.2
Van Raam, B.J.3
Marro, B.S.4
Nguyen, L.V.5
Srinivas, P.6
-
62
-
-
79952811804
-
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
-
10.1038/nature09857
-
Kaiser WJ, Upton JW, Long AB, Livingston-Rosanoff D, Daley-Bauer LP, Hakem R, et al. RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature. 2011;. doi: 10.1038/nature09857.
-
(2011)
Nature
-
-
Kaiser, W.J.1
Upton, J.W.2
Long, A.B.3
Livingston-Rosanoff, D.4
Daley-Bauer, L.P.5
Hakem, R.6
-
63
-
-
3543097542
-
RIP links TLR4 to Akt and is essential for cell survival in response to LPS stimulation
-
10.1084/jem.20040446 15280422 1:CAS:528:DC%2BD2cXmsVCkurk%3D
-
Vivarelli MS, McDonald D, Miller M, Cusson N, Kelliher M, Geha RS. RIP links TLR4 to Akt and is essential for cell survival in response to LPS stimulation. J Exp Med. 2004;200(3):399-404. doi: 10.1084/jem.20040446.
-
(2004)
J Exp Med
, vol.200
, Issue.3
, pp. 399-404
-
-
Vivarelli, M.S.1
McDonald, D.2
Miller, M.3
Cusson, N.4
Kelliher, M.5
Geha, R.S.6
-
64
-
-
29644433629
-
NF-kappaB protects macrophages from lipopolysaccharide-induced cell death: The role of caspase 8 and receptor-interacting protein
-
10.1074/jbc.M510849200 16246838 1:CAS:528:DC%2BD2MXhtlajsrjM
-
Ma Y, Temkin V, Liu H, Pope RM. NF-kappaB protects macrophages from lipopolysaccharide-induced cell death: the role of caspase 8 and receptor-interacting protein. J Biol Chem. 2005;280(51):41827-34. doi: 10.1074/jbc.M510849200.
-
(2005)
J Biol Chem
, vol.280
, Issue.51
, pp. 41827-41834
-
-
Ma, Y.1
Temkin, V.2
Liu, H.3
Pope, R.M.4
-
65
-
-
5944233768
-
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
-
10.1038/82732 11101870 1:CAS:528:DC%2BD3cXoslyru74%3D
-
Holler N, Zaru R, Micheau O, Thome M, Attinger A, Valitutti S, et al. Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol. 2000;1(6):489-95. doi: 10.1038/82732.
-
(2000)
Nat Immunol
, vol.1
, Issue.6
, pp. 489-495
-
-
Holler, N.1
Zaru, R.2
Micheau, O.3
Thome, M.4
Attinger, A.5
Valitutti, S.6
-
66
-
-
0347065342
-
A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses
-
10.1074/jbc.M305633200 14532286 1:CAS:528:DC%2BD3sXpslOgsrY%3D
-
Chan FK, Shisler J, Bixby JG, Felices M, Zheng L, Appel M, et al. A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses. J Biol Chem. 2003;278(51):51613-21. doi: 10.1074/jbc.M305633200.
-
(2003)
J Biol Chem
, vol.278
, Issue.51
, pp. 51613-51621
-
-
Chan, F.K.1
Shisler, J.2
Bixby, J.G.3
Felices, M.4
Zheng, L.5
Appel, M.6
-
67
-
-
77950366886
-
Decoding cell death signals in inflammation and immunity
-
10.1016/j.cell.2010.02.015 20303871 1:CAS:528:DC%2BC3cXlsVSgurc%3D
-
Zitvogel L, Kepp O, Kroemer G. Decoding cell death signals in inflammation and immunity. Cell. 2010;140(6):798-804. doi: 10.1016/j.cell.2010. 02.015.
-
(2010)
Cell
, vol.140
, Issue.6
, pp. 798-804
-
-
Zitvogel, L.1
Kepp, O.2
Kroemer, G.3
-
68
-
-
67349124914
-
Immunogenic and tolerogenic cell death
-
10.1038/nri2545 19365408 1:CAS:528:DC%2BD1MXksVyit7Y%3D
-
Green DR, Ferguson T, Zitvogel L, Kroemer G. Immunogenic and tolerogenic cell death. Nat Rev Immunol. 2009;9(5):353-63. doi: 10.1038/nri2545.
-
(2009)
Nat Rev Immunol
, vol.9
, Issue.5
, pp. 353-363
-
-
Green, D.R.1
Ferguson, T.2
Zitvogel, L.3
Kroemer, G.4
-
69
-
-
0033861807
-
Induction of necrotic-like cell death by tumor necrosis factor alpha and caspase inhibitors: Novel mechanism for killing virus-infected cells
-
10906200 1:CAS:528:DC%2BD3cXlt1Grs7Y%3D
-
Li M, Beg AA. Induction of necrotic-like cell death by tumor necrosis factor alpha and caspase inhibitors: novel mechanism for killing virus-infected cells. J Virol. 2000;74(16):7470-7.
-
(2000)
J Virol
, vol.74
, Issue.16
, pp. 7470-7477
-
-
Li, M.1
Beg, A.A.2
-
70
-
-
33646234026
-
Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1
-
10.1128/MCB.26.9.3505-3513.2006 16611992 1:CAS:528:DC%2BD28XksVKksLo%3D
-
Zheng L, Bidere N, Staudt D, Cubre A, Orenstein J, Chan FK, et al. Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1. Mol Cell Biol. 2006;26(9):3505-13. doi: 10.1128/MCB.26.9.3505-3513.2006.
-
(2006)
Mol Cell Biol
, vol.26
, Issue.9
, pp. 3505-3513
-
-
Zheng, L.1
Bidere, N.2
Staudt, D.3
Cubre, A.4
Orenstein, J.5
Chan, F.K.6
-
71
-
-
0032482169
-
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor
-
9565639 1:CAS:528:DyaK1cXivVGjur8%3D
-
Vercammen D, Beyaert R, Denecker G, Goossens V, Van Loo G, Declercq W, et al. Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. J Exp Med. 1998;187(9):1477-85.
-
(1998)
J Exp Med
, vol.187
, Issue.9
, pp. 1477-1485
-
-
Vercammen, D.1
Beyaert, R.2
Denecker, G.3
Goossens, V.4
Van Loo, G.5
Declercq, W.6
-
72
-
-
0031052956
-
Vaccinia virus serpin B13R (SPI-2) inhibits interleukin-1beta-converting enzyme and protects virus-infected cells from TNF- and Fas-mediated apoptosis, but does not prevent IL-1beta-induced fever
-
9049422 1:CAS:528:DyaK2sXhsVaisr4%3D
-
Kettle S, Alcami A, Khanna A, Ehret R, Jassoy C, Smith GL. Vaccinia virus serpin B13R (SPI-2) inhibits interleukin-1beta-converting enzyme and protects virus-infected cells from TNF- and Fas-mediated apoptosis, but does not prevent IL-1beta-induced fever. J Gen Virol. 1997;78(Pt 3):677-85.
-
(1997)
J Gen Virol
, vol.78
, Issue.PART 3
, pp. 677-685
-
-
Kettle, S.1
Alcami, A.2
Khanna, A.3
Ehret, R.4
Jassoy, C.5
Smith, G.L.6
-
73
-
-
0029813306
-
Protection against apoptosis by the vaccinia virus SPI-2 (B13R) gene product
-
8709286 1:CAS:528:DyaK28XkvFGgu74%3D
-
Dobbelstein M, Shenk T. Protection against apoptosis by the vaccinia virus SPI-2 (B13R) gene product. J Virol. 1996;70(9):6479-85.
-
(1996)
J Virol
, vol.70
, Issue.9
, pp. 6479-6485
-
-
Dobbelstein, M.1
Shenk, T.2
-
74
-
-
80455176839
-
Non-canonical inflammasome activation targets caspase-11
-
10.1038/nature10558 22002608 1:CAS:528:DC%2BC3MXhtlWksr7E
-
Kayagaki N, Warming S, Lamkanfi M, Vande Walle L, Louie S, Dong J, et al. Non-canonical inflammasome activation targets caspase-11. Nature. 2011;479(7371):117-21. doi: 10.1038/nature10558.
-
(2011)
Nature
, vol.479
, Issue.7371
, pp. 117-121
-
-
Kayagaki, N.1
Warming, S.2
Lamkanfi, M.3
Vande Walle, L.4
Louie, S.5
Dong, J.6
-
75
-
-
0026728952
-
Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme
-
1339309 1:CAS:528:DyaK38Xks1yiu7Y%3D
-
Ray CA, Black RA, Kronheim SR, Greenstreet TA, Sleath PR, Salvesen GS, et al. Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme. Cell. 1992;69(4):597-604.
-
(1992)
Cell
, vol.69
, Issue.4
, pp. 597-604
-
-
Ray, C.A.1
Black, R.A.2
Kronheim, S.R.3
Greenstreet, T.A.4
Sleath, P.R.5
Salvesen, G.S.6
-
76
-
-
67249158956
-
Identification of a dendritic cell receptor that couples sensing of necrosis to immunity
-
10.1038/nature07750 19219027 1:CAS:528:DC%2BD1MXhvFKjtLs%3D
-
Sancho D, Joffre OP, Keller AM, Rogers NC, Martinez D, Hernanz-Falcon P, et al. Identification of a dendritic cell receptor that couples sensing of necrosis to immunity. Nature. 2009;458(7240):899-903. doi: 10.1038/nature07750.
-
(2009)
Nature
, vol.458
, Issue.7240
, pp. 899-903
-
-
Sancho, D.1
Joffre, O.P.2
Keller, A.M.3
Rogers, N.C.4
Martinez, D.5
Hernanz-Falcon, P.6
-
77
-
-
52549125928
-
Mincle is an ITAM-coupled activating receptor that senses damaged cells
-
10.1038/ni.1651 18776906 1:CAS:528:DC%2BD1cXhtFeit7jP
-
Yamasaki S, Ishikawa E, Sakuma M, Hara H, Ogata K, Saito T. Mincle is an ITAM-coupled activating receptor that senses damaged cells. Nat Immunol. 2008;9(10):1179-88. doi: 10.1038/ni.1651.
-
(2008)
Nat Immunol
, vol.9
, Issue.10
, pp. 1179-1188
-
-
Yamasaki, S.1
Ishikawa, E.2
Sakuma, M.3
Hara, H.4
Ogata, K.5
Saito, T.6
-
78
-
-
54049145131
-
The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement
-
10.1182/blood-2008-05-155176 18669894 1:CAS:528:DC%2BD1cXht1OmurzP
-
Caminschi I, Proietto AI, Ahmet F, Kitsoulis S, Shin Teh J, Lo JC, et al. The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement. Blood. 2008;112(8):3264-73. doi: 10.1182/blood-2008-05- 155176.
-
(2008)
Blood
, vol.112
, Issue.8
, pp. 3264-3273
-
-
Caminschi, I.1
Proietto, A.I.2
Ahmet, F.3
Kitsoulis, S.4
Shin Teh, J.5
Lo, J.C.6
-
79
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha
-
10.1016/j.cell.2009.05.021 19524512 1:CAS:528:DC%2BD1MXps1eiu70%3D
-
He S, Wang L, Miao L, Wang T, Du F, Zhao L, et al. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell. 2009;137(6):1100-11. doi: 10.1016/j.cell.2009.05.021.
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1100-1111
-
-
He, S.1
Wang, L.2
Miao, L.3
Wang, T.4
Du, F.5
Zhao, L.6
-
80
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
10.1126/science.1172308 19498109 1:CAS:528:DC%2BD1MXos1Sqt7Y%3D
-
Zhang DW, Shao J, Lin J, Zhang N, Lu BJ, Lin SC, et al. RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science. 2009;325(5938):332-6. doi: 10.1126/science.1172308.
-
(2009)
Science
, vol.325
, Issue.5938
, pp. 332-336
-
-
Zhang, D.W.1
Shao, J.2
Lin, J.3
Zhang, N.4
Lu, B.J.5
Lin, S.C.6
-
81
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
10.1016/j.cell.2009.05.037 19524513 1:CAS:528:DC%2BD1MXps1eiu7o%3D
-
Cho YS, Challa S, Moquin D, Genga R, Ray TD, Guildford M, et al. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell. 2009;137(6):1112-23. doi: 10.1016/j.cell.2009.05.037.
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1112-1123
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
Genga, R.4
Ray, T.D.5
Guildford, M.6
-
82
-
-
67650638892
-
RIP kinases at the crossroads of cell death and survival
-
10.1016/j.cell.2009.07.006 19632174 1:CAS:528:DC%2BD1MXhtVSgtrzK
-
Declercq W, Vanden Berghe T, Vandenabeele P. RIP kinases at the crossroads of cell death and survival. Cell. 2009;138(2):229-32. doi: 10.1016/j.cell.2009.07.006.
-
(2009)
Cell
, vol.138
, Issue.2
, pp. 229-232
-
-
Declercq, W.1
Vanden Berghe, T.2
Vandenabeele, P.3
-
83
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
-
10.1038/nature09852 21368763 1:CAS:528:DC%2BC3MXis1Crsrs%3D
-
Oberst A, Dillon CP, Weinlich R, McCormick LL, Fitzgerald P, Pop C, et al. Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature. 2011;471(7338):363-7. doi: 10.1038/nature09852.
-
(2011)
Nature
, vol.471
, Issue.7338
, pp. 363-367
-
-
Oberst, A.1
Dillon, C.P.2
Weinlich, R.3
McCormick, L.L.4
Fitzgerald, P.5
Pop, C.6
-
84
-
-
79952780505
-
Functional complementation between FADD and RIP1 in embryos and lymphocytes
-
10.1038/nature09878 21368761 1:CAS:528:DC%2BC3MXis1Crsrg%3D
-
Zhang H, Zhou X, McQuade T, Li J, Chan FK, Zhang J. Functional complementation between FADD and RIP1 in embryos and lymphocytes. Nature. 2011;471(7338):373-6. doi: 10.1038/nature09878.
-
(2011)
Nature
, vol.471
, Issue.7338
, pp. 373-376
-
-
Zhang, H.1
Zhou, X.2
McQuade, T.3
Li, J.4
Chan, F.K.5
Zhang, J.6
-
85
-
-
80052845560
-
Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis
-
10.1038/nature10400 21921917
-
Gunther C, Martini E, Wittkopf N, Amann K, Weigmann B, Neumann H, et al. Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis. Nature. 2011;477(7364):335-9. doi: 10.1038/nature10400.
-
(2011)
Nature
, vol.477
, Issue.7364
, pp. 335-339
-
-
Gunther, C.1
Martini, E.2
Wittkopf, N.3
Amann, K.4
Weigmann, B.5
Neumann, H.6
-
86
-
-
80052850704
-
FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
-
10.1038/nature10273 21804564 1:CAS:528:DC%2BC3MXhtFersLrF
-
Welz PS, Wullaert A, Vlantis K, Kondylis V, Fernandez-Majada V, Ermolaeva M, et al. FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation. Nature. 2011;477(7364):330-4. doi: 10.1038/nature10273.
-
(2011)
Nature
, vol.477
, Issue.7364
, pp. 330-334
-
-
Welz, P.S.1
Wullaert, A.2
Vlantis, K.3
Kondylis, V.4
Fernandez-Majada, V.5
Ermolaeva, M.6
-
87
-
-
80755132824
-
The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation
-
10.1016/j.immuni.2011.08.014 22000287 1:CAS:528:DC%2BC3MXhtlyjs7zF
-
Bonnet MC, Preukschat D, Welz PS, van Loo G, Ermolaeva MA, Bloch W, et al. The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation. Immunity. 2011;35(4):572-82. doi: 10.1016/j.immuni.2011.08.014.
-
(2011)
Immunity
, vol.35
, Issue.4
, pp. 572-582
-
-
Bonnet, M.C.1
Preukschat, D.2
Welz, P.S.3
Van Loo, G.4
Ermolaeva, M.A.5
Bloch, W.6
-
88
-
-
57649181391
-
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
-
10.1016/j.cell.2008.10.044 19109899 1:CAS:528:DC%2BD1MXisFyitg%3D%3D
-
Hitomi J, Christofferson DE, Ng A, Yao J, Degterev A, Xavier RJ, et al. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell. 2008;135(7):1311-23. doi: 10.1016/j.cell.2008.10.044.
-
(2008)
Cell
, vol.135
, Issue.7
, pp. 1311-1323
-
-
Hitomi, J.1
Christofferson, D.E.2
Ng, A.3
Yao, J.4
Degterev, A.5
Xavier, R.J.6
-
89
-
-
46249124976
-
Deubiquitylation and regulation of the immune response
-
10.1038/nri2337 18535581 1:CAS:528:DC%2BD1cXns1ehs7o%3D
-
Sun SC. Deubiquitylation and regulation of the immune response. Nat Rev Immunol. 2008;8(7):501-11. doi: 10.1038/nri2337.
-
(2008)
Nat Rev Immunol
, vol.8
, Issue.7
, pp. 501-511
-
-
Sun, S.C.1
-
90
-
-
77449150629
-
CYLD: A tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes
-
10.1038/cdd.2009.43 1:CAS:528:DC%2BD1MXjslymsb0%3D
-
Sun SC. CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes. Cell Death Differ. 2009;17(1):25-34. doi: 10.1038/cdd.2009.43.
-
(2009)
Cell Death Differ
, vol.17
, Issue.1
, pp. 25-34
-
-
Sun, S.C.1
-
91
-
-
35548974703
-
Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD
-
10.1016/j.devcel.2007.09.007 17981138 1:CAS:528:DC%2BD2sXhtlWitrfE
-
Wright A, Reiley WW, Chang M, Jin W, Lee AJ, Zhang M, et al. Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD. Dev Cell. 2007;13(5):705-16. doi: 10.1016/j.devcel.2007.09.007.
-
(2007)
Dev Cell
, vol.13
, Issue.5
, pp. 705-716
-
-
Wright, A.1
Reiley, W.W.2
Chang, M.3
Jin, W.4
Lee, A.J.5
Zhang, M.6
-
92
-
-
60649110012
-
TNFalpha-induced macrophage death via caspase-dependent and independent pathways
-
10.1007/s10495-009-0311-4 19152111 1:CAS:528:DC%2BD1MXitVOrtb8%3D
-
Tran TM, Temkin V, Shi B, Pagliari L, Daniel S, Ferran C, et al. TNFalpha-induced macrophage death via caspase-dependent and independent pathways. Apoptosis. 2009;14(3):320-32. doi: 10.1007/s10495-009-0311-4.
-
(2009)
Apoptosis
, vol.14
, Issue.3
, pp. 320-332
-
-
Tran, T.M.1
Temkin, V.2
Shi, B.3
Pagliari, L.4
Daniel, S.5
Ferran, C.6
-
93
-
-
17144404884
-
Functional dichotomy of A20 in apoptotic and necrotic cell death
-
10.1042/BJ20041443 15527421 1:CAS:528:DC%2BD2MXisFWgtr0%3D
-
Storz P, Doppler H, Ferran C, Grey ST, Toker A. Functional dichotomy of A20 in apoptotic and necrotic cell death. Biochem J. 2005;387(Pt 1):47-55. doi: 10.1042/BJ20041443.
-
(2005)
Biochem J
, vol.387
, Issue.PART 1
, pp. 47-55
-
-
Storz, P.1
Doppler, H.2
Ferran, C.3
Grey, S.T.4
Toker, A.5
-
94
-
-
5444223519
-
The ubiquitin-modifying enzyme A20 is required for termination of toll-like receptor responses
-
10.1038/ni1110 15334086 1:CAS:528:DC%2BD2cXnvFCgsro%3D
-
Boone DL, Turer EE, Lee EG, Ahmad RC, Wheeler MT, Tsui C, et al. The ubiquitin-modifying enzyme A20 is required for termination of toll-like receptor responses. Nat Immunol. 2004;5(10):1052-60. doi: 10.1038/ni1110.
-
(2004)
Nat Immunol
, vol.5
, Issue.10
, pp. 1052-1060
-
-
Boone, D.L.1
Turer, E.E.2
Lee, E.G.3
Ahmad, R.C.4
Wheeler, M.T.5
Tsui, C.6
-
95
-
-
84856160569
-
CASPASE 8 inhibits programmed necrosis by processing CYLD
-
10.1038/ncb2362 22037414
-
O'Donnell MA, Perez-Jimenez E, Oberst A, Ng A, Massoumi R, Xavier R et al. CASPASE 8 inhibits programmed necrosis by processing CYLD. Nat Cell Biol. 2011;13:1437-42. doi: 10.1038/ncb2362
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1437-1442
-
-
O'Donnell, M.A.1
Perez-Jimenez, E.2
Oberst, A.3
Ng, A.4
Massoumi, R.5
Xavier, R.6
-
96
-
-
79955592698
-
T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1
-
10.1038/emboj.2011.85 21448133 1:CAS:528:DC%2BC3MXjvFOnt78%3D
-
Staal J, Driege Y, Bekaert T, Demeyer A, Muyllaert D, Van Damme P, et al. T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1. EMBO J. 2011;30(9):1742-52. doi: 10.1038/emboj.2011.85.
-
(2011)
EMBO J
, vol.30
, Issue.9
, pp. 1742-1752
-
-
Staal, J.1
Driege, Y.2
Bekaert, T.3
Demeyer, A.4
Muyllaert, D.5
Van Damme, P.6
-
97
-
-
48349125069
-
The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation
-
10.1016/j.molcel.2008.06.008 18691973 1:CAS:528:DC%2BD1cXhtVSrsrnI
-
Kawadler H, Gantz MA, Riley JL, Yang X. The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation. Mol Cell. 2008;31(3):415-21. doi: 10.1016/j.molcel.2008.06.008.
-
(2008)
Mol Cell
, vol.31
, Issue.3
, pp. 415-421
-
-
Kawadler, H.1
Gantz, M.A.2
Riley, J.L.3
Yang, X.4
-
98
-
-
77955109451
-
A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response
-
10.1038/ncb2006 20010814 1:CAS:528:DC%2BD1MXhsFynur3N
-
Ashida H, Kim M, Schmidt-Supprian M, Ma A, Ogawa M, Sasakawa C. A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory response. Nat Cell Biol. 2010;12(1):66-73. doi: 10.1038/ncb2006.
-
(2010)
Nat Cell Biol
, vol.12
, Issue.1
, pp. 66-73
-
-
Ashida, H.1
Kim, M.2
Schmidt-Supprian, M.3
Ma, A.4
Ogawa, M.5
Sasakawa, C.6
-
99
-
-
60649096938
-
Shigella targets the mitochondrial checkpoint of programmed necrosis
-
10.1016/j.chom.2009.01.002 19218080 1:CAS:528:DC%2BD1MXivFehsr8%3D
-
Galluzzi L, Kroemer G. Shigella targets the mitochondrial checkpoint of programmed necrosis. Cell Host Microbe. 2009;5(2):107-9. doi: 10.1016/j.chom.2009.01.002.
-
(2009)
Cell Host Microbe
, vol.5
, Issue.2
, pp. 107-109
-
-
Galluzzi, L.1
Kroemer, G.2
-
100
-
-
84855764312
-
Cysteine methylation disrupts ubiquitin-chain sensing in NF-kappaB activation
-
10.1038/nature10690 22158122
-
Zhang L, Ding X, Cui J, Xu H, Chen J, Gong YN, et al. Cysteine methylation disrupts ubiquitin-chain sensing in NF-kappaB activation. Nature. 2011;481(7380):204-8. doi: 10.1038/nature10690.
-
(2011)
Nature
, vol.481
, Issue.7380
, pp. 204-208
-
-
Zhang, L.1
Ding, X.2
Cui, J.3
Xu, H.4
Chen, J.5
Gong, Y.N.6
-
101
-
-
80053927315
-
The prevalence of TNFalpha-induced necrosis over apoptosis is determined by TAK1-RIP1 interplay
-
10.1371/journal.pone.0026069
-
Arslan SC, Scheidereit C. The prevalence of TNFalpha-induced necrosis over apoptosis is determined by TAK1-RIP1 interplay. PLoS ONE. 2008;6(10):e26069. doi: 10.1371/journal.pone.0026069.
-
(2008)
PLoS ONE
, vol.6
, Issue.10
, pp. 26069
-
-
Arslan, S.C.1
Scheidereit, C.2
-
102
-
-
79952623655
-
CIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production
-
10.1038/cdd.2010.138 21052097
-
Vanlangenakker N, Vanden Berge N, Berghe T, Bogaert P, Laukens B, Zoberl K, Deshayes K, et al. cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production. Cell Death Differ. 2010;18(4):656-65. doi: 10.1038/cdd.2010.138.
-
(2010)
Cell Death Differ
, vol.18
, Issue.4
, pp. 656-665
-
-
Vanlangenakker, N.1
Vanden Berge, N.2
Berghe, T.3
Bogaert, P.4
Laukens, B.5
Zoberl, K.6
Deshayes, K.7
|