Injectable controlled release depots for large molecules

Journal of Controlled Release

Volumn 190, Issue , 2014, Pages 240-253

  Schwendeman, Steven P ^a   Shah, Ronak B ^a   Bailey, Brittany A ^a   Schwendeman, Anna S ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Biodegradable; Controlled release; Depot; Peptide; PLGA; Protein

Indexed keywords

BIOCOMPATIBILITY; BIOLOGICAL MATERIALS; DRUG PRODUCTS; DRUG THERAPY; MOLECULES; PEPTIDES; PROTEINS; RESEARCH LABORATORIES; COPOLYMERS;

BIODEGRADABLE; CONTROLLED DRUG RELEASE; CONTROLLED RELEASE; DEPOT; PHARMACEUTICAL PRODUCTS; PLGA; POLY(LACTIC-CO-GLYCOLIC ACID); SYNTHETIC BIOMATERIALS;

COPOLYMERS; DRUG PRODUCTS;

GOSERELIN; LEUPRORELIN; PEPTIDE; POLYGLACTIN; POLYMER; POLYPEPTIDE; SUTURE MATERIAL; MACROGOL; OCTREOTIDE; PEGINTERFERON ALPHA2B; PEGVISOMANT; PROTEIN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; BIOMATERIAL; DELAYED RELEASE FORMULATION; DRUG CARRIER; LACTIC ACID; MACROMOLECULE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

CLINICAL EVALUATION; CONTROLLED DRUG RELEASE; CONTROLLED RELEASE FORMULATION; DRUG DELIVERY SYSTEM; DRUG MANUFACTURE; DRUG MONITORING; ENCAPSULATION; HUMAN; INJECTABLE CONTROLLED RELEASE DEPOT; MICROCLIMATE; MICROENCAPSULATION; MOLECULAR WEIGHT; MOLECULE; NANOENCAPSULATION; NEEDLE; OSMOTIC PRESSURE; PARTICLE SIZE; PH; PRIORITY JOURNAL; PROTEIN STABILITY; REVIEW; ABSORPTION; DRUG DIFFUSION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; LONG ACTING RELEASE; MISCIBILITY; NANOEMULSION; NONHUMAN; PROTEIN AGGREGATION; PROTEIN UNFOLDING; SOLID STATE; ADMINISTRATION AND DOSAGE; DELAYED RELEASE FORMULATION; DRUG FORMULATION; INJECTION; MACROMOLECULE; PHARMACOKINETICS;

BIOCOMPATIBLE MATERIALS; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG COMPOUNDING; HUMANS; INJECTIONS; LACTIC ACID; MACROMOLECULAR SUBSTANCES; PHARMACOKINETICS; POLYGLYCOLIC ACID; POLYMERS;

EID: 84906786630     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.05.057     Document Type: Review

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