A new class of inhibitors of peptide sorption and acylation in PLGA

Journal of Controlled Release

Volumn 137, Issue 3, 2009, Pages 179-184

  Sophocleous, Andreas M ^a   Zhang, Ying ^a   Schwendeman, Steven P ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Acylation; Divalent cations; Octreotide acetate; PLGA; Sorption

Indexed keywords

CONTROLLED RELEASE; DEGRADATION REACTION; DELIVERY SYSTEMS; DIVALENT CATION; DIVALENT CATIONS; END GROUPS; FREE CONTROL; GLYCOLIC ACIDS; HEPES BUFFER; IN-VITRO; INHIBITING EFFECT; MODEL PEPTIDES; NEW CLASS; OCTREOTIDE; OCTREOTIDE ACETATE; ORGANIC CARRIERS; PLGA; PRODUCT SAFETY; PSEUDO-EQUILIBRIUM; SORPTION ISOTHERMS;

ACYLATION; AMINES; ATMOSPHERIC TEMPERATURE; CALCIUM; CALCIUM CHLORIDE; DRUG PRODUCTS; DYES; MANGANESE; MANGANESE COMPOUNDS; PEPTIDES; POSITIVE IONS; SODIUM CHLORIDE;

SORPTION;

CALCIUM; CALCIUM CHLORIDE; DIVALENT CATION; DRUG CARRIER; MAGNESIUM; MANGANESE; MANGANESE CHLORIDE; NICKEL; OCTREOTIDE; POLYGLACTIN; SODIUM; SODIUM CHLORIDE;

ACYLATION; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ENCAPSULATION; IN VITRO STUDY; INCUBATION TIME; ISOTHERM; PH MEASUREMENT; PRIORITY JOURNAL; SOLUBILITY; SOLVENT EFFECT;

ACYLATION; BINDING SITES; CATIONS, DIVALENT; DRUG CARRIERS; KINETICS; LACTIC ACID; OCTREOTIDE; POLYGLYCOLIC ACID; SALTS;

EID: 67649103532     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.03.006     Document Type: Article

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