Inhibition of peptide acylation in PLGA microspheres with water-soluble divalent cationic salts

Pharmaceutical Research

Volumn 26, Issue 8, 2009, Pages 1986-1994

  Zhang, Ying ^a   Sophocleous, Andreas M ^a   Schwendeman, Steven P ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Acylation; Controlled release; Divalent cations; Peptide stability; Sorption

Indexed keywords

CALCIUM CHLORIDE; DIVALENT CATION; MANGANESE CHLORIDE; MICROSPHERE; OCTREOTIDE; POLYGLACTIN; SODIUM CHLORIDE;

ACYLATION; ARTICLE; DRUG IMPURITY; DRUG SOLUBILITY; DRUG STABILITY; EMULSION; ENCAPSULATION; FLAME PHOTOMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LEACHING; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SCANNING ELECTRON MICROSCOPY;

ACYLATION; CATIONS, DIVALENT; LACTIC ACID; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; PEPTIDES; POLYGLYCOLIC ACID; SOLUBILITY; SPECTRUM ANALYSIS;

EID: 67650066584     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-009-9914-2     Document Type: Article

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