메뉴 건너뛰기




Volumn 73, Issue 2-3, 2001, Pages 121-136

On the importance and mechanisms of burst release in matrix-controlled drug delivery systems

Author keywords

Burst release; Controlled release; Drug delivery; Modeling; Review

Indexed keywords

POLYMER;

EID: 0035850221     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00248-6     Document Type: Review
Times cited : (1520)

References (61)
  • 16
    • 0031473467 scopus 로고    scopus 로고
    • Finite element analysis of diffusional drug release from complex matrix system. I. Complex geometries and composite structured
    • (1997) J. Control. Release , vol.49 , pp. 277-288
    • Zhou, Y.1    Wu, X.Y.2
  • 18
    • 0033152277 scopus 로고    scopus 로고
    • Mechanisms of solute and drug transport in relaxing, swellable, hydrophilic glassy polymers
    • (1999) Polymer , vol.40 , pp. 3383-3398
    • Brazel, C.S.1    Peppas, N.A.2
  • 19
    • 0021469397 scopus 로고
    • Effect of non-uniform initial drug concentration distribution on the kinetics of drug release from glassy hydrogel matrices
    • (1984) Polymer , vol.25 , pp. 973-978
    • Lee, P.I.1
  • 25
    • 0027113248 scopus 로고
    • Poly(L-lactic acid)/pluronic blends: Characterization of phase separation behavior, degradation, and morphology and use as protein-releasing matrices
    • (1992) Macromolecules , vol.25 , pp. 116-122
    • Park, T.G.1    Cohen, S.2    Langer, R.3
  • 26
    • 0025053154 scopus 로고
    • Biodegradable poly(lactic acid) and poly(lactide-co-glycolide) microcapsules: Problems associated with preparative techniques and release properties
    • (1990) J. Microencapsulation , vol.7 , pp. 297-325
    • Jalil, R.1    Nixon, J.R.2
  • 32
    • 0025232145 scopus 로고
    • A thermo-sensitive hydrogel: Poly(ethylene oxide-dimethyl siloxane-ethylene oxide)/poly(N-isopropylacrylamide) interpenetrating polymer networks. II. On-off regulation of solute release from thermo-sensitive hydrogel
    • (1990) Polym. J. , vol.22 , pp. 250-265
    • Mukae, K.1    Bae, Y.H.2    Okano, T.3    Kim, S.W.4
  • 51
    • 73049134701 scopus 로고
    • Rate of release of medicaments from ointment bases containing drugs in suspension
    • (1961) J. Pharm. Sci. , vol.50 , pp. 874-875
    • Higuchi, T.1
  • 54
    • 0343891065 scopus 로고
    • The swelling interface number as a criterion for prediction of diffusional solute release mechanisms in swellable polymers
    • (1983) J. Polym. Sci. , vol.21 , pp. 983-997
    • Peppas, N.A.1    Franson, N.M.2
  • 55
    • 0023943923 scopus 로고
    • Solute and penetrant diffusion in swellable polymers. VIII. Influence of the swelling interface number on solute concentration profiles and release
    • (1988) J. Control. Release , vol.7 , pp. 61-68
    • Klier, J.1    Peppas, N.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.