Effect of polymer porosity on aqueous self-healing encapsulation of proteins in PLGA microspheres

Macromolecular Bioscience

Volumn 13, Issue 12, 2013, Pages 1700-1710

  Reinhold, Samuel E ^a   Schwendeman, Steven P ^b  

^a Upsher Smith Laboratories Inc   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

biodegradable polymers; healing; microencapsulation; porosity; proteins

Indexed keywords

ENCAPSULATION OF PROTEINS; EXTERNAL SOLUTIONS; HEALING; PHYSIOLOGICAL CONDITION; PLGA MICROSPHERES; POLY(LACTIC-CO-GLYCOLIC ACID); POLYMER GLASS TRANSITION; RELEASE KINETICS;

BIODEGRADABLE POLYMERS; BIOLOGICAL MATERIALS; COPOLYMERS; ENZYMES; MICROENCAPSULATION; MICROSPHERES; POROSITY; PROTEINS;

LOADING;

BOVINE SERUM ALBUMIN; COUMARIN; EXCIPIENT; LYSOZYME; MAGNESIUM CARBONATE; MICROSPHERE; POLYGLACTIN; POLYMER;

ARTICLE; DRUG RELEASE; EMULSION; ENZYME ACTIVITY; ENZYME RELEASE; ENZYME STABILITY; MICROENCAPSULATION; PHASE SEPARATION; POROSITY; PROTEIN AGGREGATION; PROTEIN CONTENT; PROTEIN STABILITY; SCANNING ELECTRON MICROSCOPY; VISCOSITY;

BIODEGRADABLE POLYMERS; HEALING; MICROENCAPSULATION; POROSITY; PROTEINS;

ANIMALS; BIOCOMPATIBLE MATERIALS; CATTLE; COUMARINS; DRUG COMPOUNDING; ENZYME ASSAYS; KINETICS; LACTIC ACID; MAGNESIUM; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; MOLECULAR WEIGHT; MURAMIDASE; PARTICLE SIZE; POLYGLYCOLIC ACID; POROSITY; SERUM ALBUMIN, BOVINE; WATER;

EID: 84890447930     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.201300323     Document Type: Article

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