Pore closing and opening in biodegradable polymers and their effect on the controlled release of proteins

Molecular Pharmaceutics

Volumn 4, Issue 1, 2007, Pages 104-118

  Kang, Jichao ^a,b   Schwendeman, Steven P ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b Neose Technologies Inc   (United States)

Author keywords

Biodegradable microspheres; Controlled release; Pore connectivity; Pore state; Protein delivery

Indexed keywords

DEXTRAN; DRUG VEHICLE; MICROSPHERE; POLY(LACTIC ACID CO GLYCOLIC ACID)GLUCOSE; POLYGLACTIN; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; BIODEGRADATION; CHANNEL GATING; CONFOCAL MICROSCOPY; DRUG DELIVERY SYSTEM; PRIORITY JOURNAL; PROTEIN SECRETION; SCANNING ELECTRON MICROSCOPY;

ANIMALS; CATTLE; DEXTRANS; LACTIC ACID; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; POLYGLYCOLIC ACID; POLYMERS; POROSITY; SERUM ALBUMIN, BOVINE; SOLUBILITY; TEMPERATURE;

EID: 33847185185     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp060041n     Document Type: Article

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