Understanding transporter specificity and the discrete appearance of channel-like gating domains in transporters

Frontiers in Pharmacology

Volumn 5 AUG, Issue , 2014, Pages

  Diallinas, George ^a  

^a UNIVERSITY OF ATHENS   (Greece)

Author keywords

Aspergillus nidulans; Atypical kinetics; Crystal structure; Drug transporters; Endocytosis turnover; Genetic; Model systems

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALLOPURINOL; AMINO ACID TRANSPORTER; ANTIDEPRESSANT AGENT; ANTIFUNGAL AGENT; ANTINEOPLASTIC AGENT; ANTIPROTOZOAL AGENT; CARRIER PROTEIN; CATECHOLAMINE TRANSPORTER; DIURETIC AGENT; DOPAMINE TRANSPORTER; G PROTEIN COUPLED RECEPTOR; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; MULTIDRUG RESISTANCE PROTEIN; PURINE TRANSPORTER; SEROTONIN TRANSPORTER; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; UNCLASSIFIED DRUG; CARDIAC GLYCOSIDE; GLUCOSE TRANSPORTER; MULTIDRUG RESISTANCE PROTEIN 1; PEPTIDE TRANSPORTER 1; PERMEASE; PROTON PUMP INHIBITOR; SODIUM GLUCOSE COTRANSPORTER 1; SODIUM GLUCOSE COTRANSPORTER 2; SODIUM GLUCOSE COTRANSPORTER 3; URACIL PERMEASE;

AMINO ACID SEQUENCE; BINDING AFFINITY; BINDING SITE; BIOCHEMISTRY; CELL MEMBRANE; CHANNEL GATING; COMPUTER MODEL; CYTOPLASM; DRUG PENETRATION; DRUG RESEARCH; DRUG TARGETING; DRUG TRANSPORT; EMERICELLA NIDULANS; ENZYME SPECIFICITY; GENETIC ANALYSIS; HUMAN; MOLECULAR INTERACTION; NONHUMAN; PHYLOGENY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN INTERACTION; PROTEIN METABOLISM; PROTEIN STRUCTURE; PROTEIN TRANSPORT; REVIEW; SEQUENCE HOMOLOGY; STRUCTURAL HOMOLOGY; STRUCTURE ACTIVITY RELATION; TRANSPORT KINETICS; ASCOMYCETES; CELL COMMUNICATION; CHEMICAL STRUCTURE; CONFORMATIONAL TRANSITION; DRUG MECHANISM; DRUG STRUCTURE; DRUG UPTAKE; ENZYME INHIBITION; ENZYME SUBSTRATE; GOUT; LEISHMANIASIS; MICHAELIS MENTEN KINETICS; NEUROTRANSMISSION; NUTRITION; SIGNAL TRANSDUCTION; SOLUTE; TRYPANOSOMIASIS;

EID: 84906512759     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2014.00207     Document Type: Review

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