Modelling, substrate docking and mutational analysis identify residues essential for function and specificity of the major fungal purine transporter AzgA

Molecular Microbiology

Volumn 93, Issue 1, 2014, Pages 129-145

  Krypotou, Emilia ^a   Lambrinidis, George ^a   Evangelidis, Thomas ^a   Mikros, Emmanuel ^a   Diallinas, George ^a  

^a UNIVERSITY OF ATHENS   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; AZGA PROTEIN; FUNGAL PROTEIN; GUANINE; HYPOXANTHINE; UNCLASSIFIED DRUG; AMINO ACID; HYDROGEN; NUCLEOBASE TRANSPORTER; PURINE; PURINE DERIVATIVE;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; EMERICELLA NIDULANS; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR PHYLOGENY; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PHYLOGENETIC TREE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; RESIDUE ANALYSIS; SEQUENCE ALIGNMENT; SOLVATION; ASPERGILLUS NIDULANS; BINDING SITE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; METABOLISM; PHYLOGENY; PHYSIOLOGY; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE;

AMINO ACIDS; ASPERGILLUS NIDULANS; BINDING SITES; DNA MUTATIONAL ANALYSIS; FUNGAL PROTEINS; HYDROGEN; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; NUCLEOBASE TRANSPORT PROTEINS; PHYLOGENY; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PURINES; SUBSTRATE SPECIFICITY;

EID: 84903380425     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/mmi.12646     Document Type: Article

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