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Volumn 50, Issue 11, 2011, Pages 1848-1856

The role of local hydration and hydrogen-bonding dynamics in ion and solute release from ion-coupled secondary transporters

Author keywords

[No Author keywords available]

Indexed keywords

BINDING AND RELEASE; CONFORMATIONAL DYNAMICS; CRYSTALLOGRAPHIC STUDIES; DEGENERATE STATE; DYNAMICAL EQUILIBRIUM; EQUILIBRIUM MOLECULAR DYNAMICS; EXTRACELLULAR; HYDROGEN BONDINGS; MOLECULAR DYNAMICS SIMULATIONS; POTENTIAL OF MEAN FORCE; RECENT PROGRESS; SODIUM BINDING; SODIUM IONS; STRUCTURAL ORGANIZATION; TRANSPORT CYCLE;

EID: 79952811744     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101454f     Document Type: Article
Times cited : (47)

References (46)
  • 1
    • 66249098083 scopus 로고    scopus 로고
    • Unlocking the molecular secrets of sodium-coupled transporters
    • Krishnamurthy, H., Piscitelli, C. L., and Gouaux, E. (2009) Unlocking the molecular secrets of sodium-coupled transporters Nature 459, 347-355
    • (2009) Nature , vol.459 , pp. 347-355
    • Krishnamurthy, H.1    Piscitelli, C.L.2    Gouaux, E.3
  • 5
    • 34247233255 scopus 로고    scopus 로고
    • Serotonin transporters-Structure and function
    • Rudnick, G. (2006) Serotonin transporters-Structure and function J. Membr. Biol. 213, 101-110
    • (2006) J. Membr. Biol. , vol.213 , pp. 101-110
    • Rudnick, G.1
  • 12
    • 78650297251 scopus 로고    scopus 로고
    • The structural basis of secondary active transport mechanisms
    • Forrest, L. R., Kramer, R., and Ziegler, C. (2011) The structural basis of secondary active transport mechanisms Biochim. Biophys. Acta 1807, 167-188
    • (2011) Biochim. Biophys. Acta , vol.1807 , pp. 167-188
    • Forrest, L.R.1    Kramer, R.2    Ziegler, C.3
  • 13
    • 0014029736 scopus 로고
    • Simple allosteric model for membrane pumps
    • Jardetzk, O. (1966) Simple allosteric model for membrane pumps Nature 211, 969
    • (1966) Nature , vol.211 , pp. 969
    • Jardetzk, O.1
  • 14
    • 7244254186 scopus 로고    scopus 로고
    • Structure of a glutamate transporter homologue from Pyrococcus horikoshii
    • DOI 10.1038/nature03018
    • Yernool, D., Boudker, O., Jin, Y., and Gouaux, E. (2004) Structure of a glutamate transporter homologue from Pyrococcus horikoshii Nature 431, 811-818 (Pubitemid 39434071)
    • (2004) Nature , vol.431 , Issue.7010 , pp. 811-818
    • Yernool, D.1    Boudker, O.2    Jin, Y.3    Gouaux, E.4
  • 15
    • 41449093586 scopus 로고    scopus 로고
    • Substrate binding and formation of an occluded state in the leucine transporter
    • Celik, L., Schiott, B., and Tajkhorshid, E. (2008) Substrate binding and formation of an occluded state in the leucine transporter Biophys. J. 94, 1600-1612
    • (2008) Biophys. J. , vol.94 , pp. 1600-1612
    • Celik, L.1    Schiott, B.2    Tajkhorshid, E.3
  • 16
    • 40649098564 scopus 로고    scopus 로고
    • + binding sites with two different mechanisms
    • + binding sites with two different mechanisms J. Mol. Biol. 377, 804-818
    • (2008) J. Mol. Biol. , vol.377 , pp. 804-818
    • Noskov, S.Y.1    Roux, B.2
  • 18
    • 79952792900 scopus 로고    scopus 로고
    • Zhao, C. F., Lei, S., and Noskov, S. Y. (2010) unpublished results
    • Zhao, C. F., Lei, S., and Noskov, S. Y. (2010) unpublished results.
  • 20
    • 72249106725 scopus 로고    scopus 로고
    • Ion-releasing state of a secondary membrane transporter
    • Li, J. and Tajkhorshid, E. (2009) Ion-releasing state of a secondary membrane transporter Biophys. J. 97, L29-L31
    • (2009) Biophys. J. , vol.97
    • Li, J.1    Tajkhorshid, E.2
  • 22
    • 79952784546 scopus 로고    scopus 로고
    • personal communication
    • Shi, L. (2010) personal communication.
    • (2010)
    • Shi, L.1
  • 23
    • 44949086583 scopus 로고    scopus 로고
    • + and Substrate is Triggered by Substrate in a Second Binding Site
    • DOI 10.1016/j.molcel.2008.05.008, PII S1097276508003596
    • + and substrate is triggered by substrate in a second binding site Mol. Cell 30, 667-677 (Pubitemid 351815131)
    • (2008) Molecular Cell , vol.30 , Issue.6 , pp. 667-677
    • Shi, L.1    Quick, M.2    Zhao, Y.3    Weinstein, H.4    Javitch, J.A.5
  • 24
    • 77953307336 scopus 로고    scopus 로고
    • Evaluations of the absolute and relative free energies for antidepressant binding to the amino acid membrane transporter leut with free energy simulations
    • Zhao, C. F., Caplan, D. A., and Noskov, S. Y. (2010) Evaluations of the absolute and relative free energies for antidepressant binding to the amino acid membrane transporter leut with free energy simulations J. Chem. Theory Comput. 6, 1900-1914
    • (2010) J. Chem. Theory Comput. , vol.6 , pp. 1900-1914
    • Zhao, C.F.1    Caplan, D.A.2    Noskov, S.Y.3
  • 25
    • 58149311441 scopus 로고    scopus 로고
    • Molecular mechanism of substrate specificity in the bacterial neutral amino acid transporter LeuT
    • Noskov, S. Y. (2008) Molecular mechanism of substrate specificity in the bacterial neutral amino acid transporter LeuT Proteins: Struct., Funct., Bioinf. 73, 851-863
    • (2008) Proteins: Struct., Funct., Bioinf. , vol.73 , pp. 851-863
    • Noskov, S.Y.1
  • 32
    • 33750606030 scopus 로고    scopus 로고
    • Molecular dynamics - potential of mean force calculations as a tool for understanding ion permeation and selectivity in narrow channels
    • DOI 10.1016/j.bpc.2006.04.015, PII S0301462206001311
    • Allen, T. W., Andersen, O. S., and Roux, B. (2006) Molecular dynamics-Potential of mean force calculations as a tool for understanding ion permeation and selectivity in narrow channels Biophys. Chem. 124, 251-267 (Pubitemid 44692362)
    • (2006) Biophysical Chemistry , vol.124 , Issue.3 , pp. 251-267
    • Allen, T.W.1    Andersen, O.S.2    Roux, B.3
  • 33
    • 0029633155 scopus 로고
    • The calculation of the potential of mean force using computer simulations
    • Roux, B. (1995) The calculation of the potential of mean force using computer simulations Comput. Phys. Commun. 91, 275-282
    • (1995) Comput. Phys. Commun. , vol.91 , pp. 275-282
    • Roux, B.1
  • 34
    • 84986519238 scopus 로고
    • The weighted histogram analysis method for free-energy calculations on biomolecules. 1. The method
    • Kumar, S., Bouzida, D., Swendsen, R. H., Kollman, P. A., and Rosenberg, J. M. (1992) The weighted histogram analysis method for free-energy calculations on biomolecules. 1. The method J. Comput. Chem. 13, 1011-1021
    • (1992) J. Comput. Chem. , vol.13 , pp. 1011-1021
    • Kumar, S.1    Bouzida, D.2    Swendsen, R.H.3    Kollman, P.A.4    Rosenberg, J.M.5
  • 36
    • 77949634796 scopus 로고    scopus 로고
    • Normal mode analysis of biomolecular structures: Functional mechanisms of membrane proteins
    • Bahar, I., Lezon, T. R., Bakan, A., and Shrivastava, I. H. (2010) Normal mode analysis of biomolecular structures: Functional mechanisms of membrane proteins Chem. Rev. 110, 1463-1497
    • (2010) Chem. Rev. , vol.110 , pp. 1463-1497
    • Bahar, I.1    Lezon, T.R.2    Bakan, A.3    Shrivastava, I.H.4
  • 37
    • 58149233796 scopus 로고    scopus 로고
    • A competitive inhibitor traps LeuT in an open-to-out conformation
    • Singh, S. K., Piscitelli, C. L., Yamashita, A., and Gouaux, E. (2008) A competitive inhibitor traps LeuT in an open-to-out conformation Science 322, 1655-1661
    • (2008) Science , vol.322 , pp. 1655-1661
    • Singh, S.K.1    Piscitelli, C.L.2    Yamashita, A.3    Gouaux, E.4
  • 38
    • 41949124711 scopus 로고    scopus 로고
    • +/proline transporter PutP of Escherichia coli in ligand binding and transport
    • +/proline transporter PutP of Escherichia coli in ligand binding and transport J. Biol. Chem. 283, 4921-4929
    • (2008) J. Biol. Chem. , vol.283 , pp. 4921-4929
    • Hilger, D.1    Bohm, M.2    Hackmann, A.3    Jung, H.4
  • 40
    • 33846625994 scopus 로고    scopus 로고
    • Importance of hydration and dynamics on the selectivity of the KcsA and NaK channels
    • DOI 10.1085/jgp.200609633
    • Noskov, S. Y. and Roux, B. (2007) Importance of hydration and dynamics on the selectivity of the KcsA and NaK channels J. Gen. Physiol. 129, 135-143 (Pubitemid 46184871)
    • (2007) Journal of General Physiology , vol.129 , Issue.2 , pp. 135-143
    • Noskov, S.Yu.1    Roux, B.2
  • 41
    • 17044400911 scopus 로고    scopus 로고
    • A gate in the selectivity filter of potassium channels
    • Berneche, S. and Roux, B. I. (2005) A gate in the selectivity filter of potassium channels Structure 13, 591-600
    • (2005) Structure , vol.13 , pp. 591-600
    • Berneche, S.1    Roux, B.I.2
  • 43
    • 79955780433 scopus 로고    scopus 로고
    • Opposite movement of the external gate of a glutamate transporter homologue upon binding co-transported sodium compared to substrate
    • (2011), (in press).
    • Focke, P., Moenne-Loccoz, P., and Larsson, H. P. (2011) Opposite movement of the external gate of a glutamate transporter homologue upon binding co-transported sodium compared to substrate, J. Neurosci. (in press).
    • J. Neurosci.
    • Focke, P.1    Moenne-Loccoz, P.2    Larsson, H.P.3
  • 44
    • 35649001607 scopus 로고
    • A quantitative description of membrane current and its application to conduction and excitation in nerve
    • Hodgkin, A. L. and Huxley, A. F. (1952) A quantitative description of membrane current and its application to conduction and excitation in nerve J. Physiol. (London) 117, 500-544
    • (1952) J. Physiol. (London) , vol.117 , pp. 500-544
    • Hodgkin, A.L.1    Huxley, A.F.2
  • 45
    • 0026512861 scopus 로고
    • The patch clamp technique
    • Neher, E. and Sakmann, B. (1992) The patch clamp technique Sci. Am. 266, 44-51
    • (1992) Sci. Am. , vol.266 , pp. 44-51
    • Neher, E.1    Sakmann, B.2


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