Flexible gates generate occluded intermediates in the transport cycle of LacY

Journal of Molecular Biology

Volumn 426, Issue 3, 2014, Pages 735-751

  Stelzl, Lukas S ^a   Fowler, Philip W ^a   Sansom, Mark S P ^a   Beckstein, Oliver ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b ARIZONA STATE UNIVERSITY   (United States)

Author keywords

major facilitator superfamily transporters; membrane permeation; molecular dynamics simulations; protein conformational change; protons

Indexed keywords

LACTOSE PERMEASE; PROTON;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME CONFORMATION; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN TRANSPORT; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CLUSTER ANALYSIS; COMPARATIVE STUDY; ION TRANSPORT; MEMBRANE POTENTIAL; PROTEIN CONFORMATION; WATER PERMEABILITY; X RAY CRYSTALLOGRAPHY;

CELL MEMBRANE; CRYSTALLOGRAPHY, X-RAY; MEMBRANE TRANSPORT PROTEINS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION; PROTEIN TRANSPORT; SYMPORTERS;

EID: 84892518651     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.10.024     Document Type: Article

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