메뉴 건너뛰기




Volumn 210, Issue 5, 2013, Pages 891-904

p53 integrates host defense and cell fate during bacterial pneumonia

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P53; ANTIINFECTIVE AGENT; NITRIC OXIDE; TOLL LIKE RECEPTOR;

EID: 84879577081     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20121674     Document Type: Article
Times cited : (50)

References (56)
  • 1
    • 77957850069 scopus 로고    scopus 로고
    • p53 and NF-κB: different strategies for responding to stress lead to a functional antagonism
    • Ak, P., and A.J. Levine. 2010. p53 and NF-κB: different strategies for responding to stress lead to a functional antagonism. FASEB J. 24:3643-3652. http://dx.doi.org/10.1096/fj.10-160549
    • (2010) FASEB J. , vol.24 , pp. 3643-3652
    • Ak, P.1    Levine, A.J.2
  • 2
    • 0032555132 scopus 로고    scopus 로고
    • Up-regulation of inducible nitric oxide synthase expression in cancer-prone p53 knockout mice
    • Ambs, S., M.O. Ogunfusika, W.G. Merriam, W.P. Bennett, T.R. Billiar, and C.C. Harris. 1998. Up-regulation of inducible nitric oxide synthase expression in cancer-prone p53 knockout mice. Proc. Natl. Acad. Sci. USA. 95:8823-8828. http://dx.doi.org/10.1073/pnas.95.15.8823
    • (1998) Proc. Natl. Acad. Sci. USA. , vol.95 , pp. 8823-8828
    • Ambs, S.1    Ogunfusika, M.O.2    Merriam, W.G.3    Bennett, W.P.4    Billiar, T.R.5    Harris, C.C.6
  • 3
    • 0031836105 scopus 로고    scopus 로고
    • Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis
    • Belaaouaj, A., R. McCarthy, M. Baumann, Z. Gao, T.J. Ley, S.N. Abraham, and S.D. Shapiro. 1998. Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis. Nat. Med. 4:615-618. http://dx.doi.org/10.1038/nm0598-615
    • (1998) Nat. Med. , vol.4 , pp. 615-618
    • Belaaouaj, A.1    McCarthy, R.2    Baumann, M.3    Gao, Z.4    Ley, T.J.5    Abraham, S.N.6    Shapiro, S.D.7
  • 5
    • 79952234493 scopus 로고    scopus 로고
    • p53 mediates cigarette smoke-induced apoptosis of pulmonary endothelial cells: inhibitory effects of macrophage migration inhibitor factor
    • Damico, R., T. Simms, B.S. Kim, Z. Tekeste, H. Amankwan, M. Damarla, and P.M. Hassoun. 2011. p53 mediates cigarette smoke-induced apoptosis of pulmonary endothelial cells: inhibitory effects of macrophage migration inhibitor factor. Am. J. Respir. Cell Mol. Biol. 44:323-332. http://dx.doi.org/10.1165/rcmb.2009-0379OC
    • (2011) Am. J. Respir. Cell Mol. Biol. , vol.44 , pp. 323-332
    • Damico, R.1    Simms, T.2    Kim, B.S.3    Tekeste, Z.4    Amankwan, H.5    Damarla, M.6    Hassoun, P.M.7
  • 6
    • 2942614991 scopus 로고    scopus 로고
    • Differential regulation of TNF-R1 signaling: lipid raft dependency of p42mapk/erk2 activation, but not NF-kappaB activation
    • Doan, J.E., D.A. Windmiller, and D.W. Riches. 2004. Differential regulation of TNF-R1 signaling: lipid raft dependency of p42mapk/erk2 activation, but not NF-kappaB activation. J. Immunol. 172:7654-7660.
    • (2004) J. Immunol. , vol.172 , pp. 7654-7660
    • Doan, J.E.1    Windmiller, D.A.2    Riches, D.W.3
  • 7
    • 0242662781 scopus 로고    scopus 로고
    • Alveolar macrophage apoptosis contributes to pneumococcal clearance in a resolving model of pulmonary infection
    • Dockrell, D.H., H.M. Marriott, L.R. Prince, V.C. Ridger, P.G. Ince, P.G. Hellewell, and M.K. Whyte. 2003. Alveolar macrophage apoptosis contributes to pneumococcal clearance in a resolving model of pulmonary infection. J. Immunol. 171:5380-5388.
    • (2003) J. Immunol. , vol.171 , pp. 5380-5388
    • Dockrell, D.H.1    Marriott, H.M.2    Prince, L.R.3    Ridger, V.C.4    Ince, P.G.5    Hellewell, P.G.6    Whyte, M.K.7
  • 8
    • 0032570820 scopus 로고    scopus 로고
    • Tumor necrosis factor-induced apoptosis stimulates p53 accumulation and p21WAF1 proteolysis in ME-180 cells
    • Donato, N.J., and M. Perez. 1998. Tumor necrosis factor-induced apoptosis stimulates p53 accumulation and p21WAF1 proteolysis in ME-180 cells. J. Biol. Chem. 273:5067-5072. http://dx.doi.org/10.1074/jbc.273.9.5067
    • (1998) J. Biol. Chem. , vol.273 , pp. 5067-5072
    • Donato, N.J.1    Perez, M.2
  • 11
    • 33846914830 scopus 로고    scopus 로고
    • The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages
    • Dzhagalov, I., A. St John, and Y.W. He. 2007. The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages. Blood. 109:1620-1626. http://dx.doi.org/10.1182/blood-2006-03-013771
    • (2007) Blood. , vol.109 , pp. 1620-1626
    • Dzhagalov, I.1    St John, A.2    He, Y.W.3
  • 12
    • 77955417711 scopus 로고    scopus 로고
    • Comprehensive analysis of TLR4-induced transcriptional responses in interleukin 4-primed mouse macrophages
    • El Chartouni, C., and M. Rehli. 2010. Comprehensive analysis of TLR4-induced transcriptional responses in interleukin 4-primed mouse macrophages. Immunobiology. 215:780-787. http://dx.doi.org/10.1016/j.imbio.2010.05.032
    • (2010) Immunobiology. , vol.215 , pp. 780-787
    • El Chartouni, C.1    Rehli, M.2
  • 15
    • 0036391974 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase is a regulator of chemokine production: relevance for the pathogenesis of shock and inflammation
    • Haskó, G., J.G. Mabley, Z.H. Németh, P. Pacher, E.A. Deitch, and C. Szabó. 2002. Poly(ADP-ribose) polymerase is a regulator of chemokine production: relevance for the pathogenesis of shock and inflammation. Mol. Med. 8:283-289.
    • (2002) Mol. Med. , vol.8 , pp. 283-289
    • Haskó, G.1    Mabley, J.G.2    Németh, Z.H.3    Pacher, P.4    Deitch, E.A.5    Szabó, C.6
  • 18
    • 0036143018 scopus 로고    scopus 로고
    • Phosphatidylserinedependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation
    • Huynh, M.L., V.A. Fadok, and P.M. Henson. 2002. Phosphatidylserinedependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation. J. Clin. Invest. 109:41-50.
    • (2002) J. Clin. Invest. , vol.109 , pp. 41-50
    • Huynh, M.L.1    Fadok, V.A.2    Henson, P.M.3
  • 19
    • 70350565471 scopus 로고    scopus 로고
    • p53-a Jack of all trades but master of none
    • Junttila, M.R., and G.I. Evan. 2009. p53-a Jack of all trades but master of none. Nat. Rev. Cancer. 9:821-829. http://dx.doi.org/10.1038/nrc2728
    • (2009) Nat. Rev. Cancer. , vol.9 , pp. 821-829
    • Junttila, M.R.1    Evan, G.I.2
  • 20
    • 0028505429 scopus 로고
    • TRANSFAC retrieval program: a network model database of eukaryotic transcription regulating sequences and proteins
    • Knüppel, R., P. Dietze, W. Lehnberg, K. Frech, and E. Wingender. 1994. TRANSFAC retrieval program: a network model database of eukaryotic transcription regulating sequences and proteins. J. Comput. Biol. 1:191-198. http://dx.doi.org/10.1089/cmb.1994.1.191
    • (1994) J. Comput. Biol. , vol.1 , pp. 191-198
    • Knüppel, R.1    Dietze, P.2    Lehnberg, W.3    Frech, K.4    Wingender, E.5
  • 23
    • 67649310514 scopus 로고    scopus 로고
    • Heatkilled bacteria induce genome instability in mouse small intestine, liver and spleen tissues
    • Koturbash, I., J.E. Thomas, O. Kovalchuk, and I. Kovalchuk. 2009. Heatkilled bacteria induce genome instability in mouse small intestine, liver and spleen tissues. Cell Cycle. 8:1935-1939. http://dx.doi.org/10.4161/cc.8.12.8797
    • (2009) Cell Cycle. , vol.8 , pp. 1935-1939
    • Koturbash, I.1    Thomas, J.E.2    Kovalchuk, O.3    Kovalchuk, I.4
  • 24
    • 33646757232 scopus 로고    scopus 로고
    • The complexity of p53 stabilization and activation
    • Lavin, M.F., and N. Gueven. 2006. The complexity of p53 stabilization and activation. Cell Death Differ. 13:941-950. http://dx.doi.org/10.1038/sj.cdd.4401925
    • (2006) Cell Death Differ. , vol.13 , pp. 941-950
    • Lavin, M.F.1    Gueven, N.2
  • 25
    • 34247127884 scopus 로고    scopus 로고
    • Impaired host defense in mice lacking ONZIN
    • Ledford, J.G., M. Kovarova, and B.H. Koller. 2007. Impaired host defense in mice lacking ONZIN. J. Immunol. 178:5132-5143.
    • (2007) J. Immunol. , vol.178 , pp. 5132-5143
    • Ledford, J.G.1    Kovarova, M.2    Koller, B.H.3
  • 26
    • 77953578553 scopus 로고    scopus 로고
    • A small molecule inhibitor of p53 stimulates amplification of hematopoietic stem cells but does not promote tumor development in mice
    • Leonova, K.I., J. Shneyder, M.P. Antoch, I.A. Toshkov, L.R. Novototskaya, P.G. Komarov, E.A. Komarova, and A.V. Gudkov. 2010. A small molecule inhibitor of p53 stimulates amplification of hematopoietic stem cells but does not promote tumor development in mice. Cell Cycle. 9:1434-1443. http://dx.doi.org/10.4161/cc.9.7.11508
    • (2010) Cell Cycle. , vol.9 , pp. 1434-1443
    • Leonova, K.I.1    Shneyder, J.2    Antoch, M.P.3    Toshkov, I.A.4    Novototskaya, L.R.5    Komarov, P.G.6    Komarova, E.A.7    Gudkov, A.V.8
  • 27
    • 59649113226 scopus 로고    scopus 로고
    • GADEM: a genetic algorithm guided formation of spaced dyads coupled with an EM algorithm for motif discovery
    • Li, L. 2009. GADEM: a genetic algorithm guided formation of spaced dyads coupled with an EM algorithm for motif discovery. J. Comput. Biol. 16: 317-329. http://dx.doi.org/10.1089/cmb.2008.16TT
    • (2009) J. Comput. Biol. , vol.16 , pp. 317-329
    • Li, L.1
  • 28
    • 66549115702 scopus 로고    scopus 로고
    • Targeted deletion of tumor suppressor PTEN augments neutrophil function and enhances host defense in neutropenia-associated pneumonia
    • Li, Y., Y. Jia, M. Pichavant, F. Loison, B. Sarraj, A. Kasorn, J. You, B.E. Robson, D.T. Umetsu, J.P. Mizgerd, et al. 2009. Targeted deletion of tumor suppressor PTEN augments neutrophil function and enhances host defense in neutropenia-associated pneumonia. Blood. 113:4930-4941. http://dx.doi.org/10.1182/blood-2008-06-161414
    • (2009) Blood. , vol.113 , pp. 4930-4941
    • Li, Y.1    Jia, Y.2    Pichavant, M.3    Loison, F.4    Sarraj, B.5    Kasorn, A.6    You, J.7    Robson, B.E.8    Umetsu, D.T.9    Mizgerd, J.P.10
  • 29
    • 65249084110 scopus 로고    scopus 로고
    • p53 Attenuates lipopolysaccharide-induced NF-kappaB activation and acute lung injury
    • Liu, G., Y.J. Park, Y. Tsuruta, E. Lorne, and E. Abraham. 2009. p53 Attenuates lipopolysaccharide-induced NF-kappaB activation and acute lung injury. J. Immunol. 182:5063-5071. http://dx.doi.org/10.4049/jimmunol.0803526
    • (2009) J. Immunol. , vol.182 , pp. 5063-5071
    • Liu, G.1    Park, Y.J.2    Tsuruta, Y.3    Lorne, E.4    Abraham, E.5
  • 30
    • 33750350774 scopus 로고    scopus 로고
    • Decreased alveolar macrophage apoptosis is associated with increased pulmonary inflammation in a murine model of pneumococcal pneumonia
    • Marriott, H.M., P.G. Hellewell, S.S. Cross, P.G. Ince, M.K. Whyte, and D.H. Dockrell. 2006. Decreased alveolar macrophage apoptosis is associated with increased pulmonary inflammation in a murine model of pneumococcal pneumonia. J. Immunol. 177:6480-6488.
    • (2006) J. Immunol. , vol.177 , pp. 6480-6488
    • Marriott, H.M.1    Hellewell, P.G.2    Cross, S.S.3    Ince, P.G.4    Whyte, M.K.5    Dockrell, D.H.6
  • 31
    • 60549103394 scopus 로고    scopus 로고
    • Efferocytosis impairs pulmonary macrophage and lung antibacterial function via PGE2/EP2 signaling
    • Medeiros, A.I., C.H. Serezani, S.P. Lee, and M. Peters-Golden. 2009. Efferocytosis impairs pulmonary macrophage and lung antibacterial function via PGE2/EP2 signaling. J. Exp. Med. 206:61-68. http://dx.doi.org/10.1084/jem.20082058
    • (2009) J. Exp. Med. , vol.206 , pp. 61-68
    • Medeiros, A.I.1    Serezani, C.H.2    Lee, S.P.3    Peters-Golden, M.4
  • 32
    • 70349438905 scopus 로고    scopus 로고
    • The expanding universe of p53 targets
    • Menendez, D., A. Inga, and M.A. Resnick. 2009. The expanding universe of p53 targets. Nat. Rev. Cancer. 9:724-737. http://dx.doi.org/10.1038/nrc2730
    • (2009) Nat. Rev. Cancer. , vol.9 , pp. 724-737
    • Menendez, D.1    Inga, A.2    Resnick, M.A.3
  • 33
    • 16444370187 scopus 로고    scopus 로고
    • Endogenous p53 protects vascular smooth muscle cells from apoptosis and reduces atherosclerosis in ApoE knockout mice
    • Mercer, J., N. Figg, V. Stoneman, D. Braganza, and M.R. Bennett. 2005. Endogenous p53 protects vascular smooth muscle cells from apoptosis and reduces atherosclerosis in ApoE knockout mice. Circ. Res. 96:667-674. http://dx.doi.org/10.1161/01.RES.0000161069.15577.ca
    • (2005) Circ. Res. , vol.96 , pp. 667-674
    • Mercer, J.1    Figg, N.2    Stoneman, V.3    Braganza, D.4    Bennett, M.R.5
  • 34
    • 0042190568 scopus 로고    scopus 로고
    • Macrophage-specific p53 expression plays a crucial role in atherosclerosis development and plaque remodeling
    • Merched, A.J., E. Williams, and L. Chan. 2003. Macrophage-specific p53 expression plays a crucial role in atherosclerosis development and plaque remodeling. Arterioscler. Thromb. Vasc. Biol. 23:1608-1614. http://dx.doi.org/10.1161/01.ATV.0000084825.88022.53
    • (2003) Arterioscler. Thromb. Vasc. Biol. , vol.23 , pp. 1608-1614
    • Merched, A.J.1    Williams, E.2    Chan, L.3
  • 35
    • 80054036585 scopus 로고    scopus 로고
    • Proteomic profiling of S-acylated macrophage proteins identifies a role for palmitoylation in mitochondrial targeting of phospholipid scramblase 3
    • Merrick, B.A., S. Dhungana, J.G. Williams, J.J. Aloor, S. Peddada, K.B. Tomer, and M.B. Fessler. 2011. Proteomic profiling of S-acylated macrophage proteins identifies a role for palmitoylation in mitochondrial targeting of phospholipid scramblase 3. Mol. Cell. Proteomics. 10:M110.006007.
    • (2011) Mol. Cell. Proteomics. , vol.10
    • Merrick, B.A.1    Dhungana, S.2    Williams, J.G.3    Aloor, J.J.4    Peddada, S.5    Tomer, K.B.6    Fessler, M.B.7
  • 36
    • 0034726015 scopus 로고    scopus 로고
    • Increased expression of p53 and Bax in the spinal cords of rats with experimental autoimmune encephalomyelitis
    • Moon, C., S. Kim, M. Wie, H. Kim, J. Cheong, J. Park, Y. Jee, N. Tanuma, Y. Matsumoto, and T. Shin. 2000. Increased expression of p53 and Bax in the spinal cords of rats with experimental autoimmune encephalomyelitis. Neurosci. Lett. 289:41-44. http://dx.doi.org/10.1016/S0304-3940(00)01253-2
    • (2000) Neurosci. Lett. , vol.289 , pp. 41-44
    • Moon, C.1    Kim, S.2    Wie, M.3    Kim, H.4    Cheong, J.5    Park, J.6    Jee, Y.7    Tanuma, N.8    Matsumoto, Y.9    Shin, T.10
  • 38
    • 58149200952 scopus 로고    scopus 로고
    • UniPROBE: an online database of protein binding microarray data on protein-DNA interactions
    • Newburger, D.E., and M.L. Bulyk. 2009. UniPROBE: an online database of protein binding microarray data on protein-DNA interactions. Nucleic Acids Res. 37:D77-D82. http://dx.doi.org/10.1093/nar/gkn660
    • (2009) Nucleic Acids Res. , vol.37
    • Newburger, D.E.1    Bulyk, M.L.2
  • 42
    • 0041345735 scopus 로고    scopus 로고
    • Tumor suppressor p53 and its homologue p73alpha affect cell migration
    • Sablina, A.A., P.M. Chumakov, and B.P. Kopnin. 2003. Tumor suppressor p53 and its homologue p73alpha affect cell migration. J. Biol. Chem. 278:27362-27371. http://dx.doi.org/10.1074/jbc. M300547200
    • (2003) J. Biol. Chem. , vol.278 , pp. 27362-27371
    • Sablina, A.A.1    Chumakov, P.M.2    Kopnin, B.P.3
  • 44
    • 0347125328 scopus 로고    scopus 로고
    • JASPAR: an open-access database for eukaryotic transcription factor binding profiles
    • Sandelin, A., W. Alkema, P. Engström, W.W. Wasserman, and B. Lenhard. 2004. JASPAR: an open-access database for eukaryotic transcription factor binding profiles. Nucleic Acids Res. 32:D91-D94. http://dx.doi.org/10.1093/nar/gkh012
    • (2004) Nucleic Acids Res. , vol.32
    • Sandelin, A.1    Alkema, W.2    Engström, P.3    Wasserman, W.W.4    Lenhard, B.5
  • 47
    • 70149089300 scopus 로고    scopus 로고
    • Human neutrophils kill Streptococcus pneumoniae via serine proteases
    • Standish, A.J., and J.N. Weiser. 2009. Human neutrophils kill Streptococcus pneumoniae via serine proteases. J. Immunol. 183:2602-2609. http://dx.doi.org/10.4049/jimmunol.0900688
    • (2009) J. Immunol. , vol.183 , pp. 2602-2609
    • Standish, A.J.1    Weiser, J.N.2
  • 48
    • 70949084458 scopus 로고    scopus 로고
    • Leukocyte elastase induces lung epithelial apoptosis via a PAR-1-, NF-kappaB-, and p53-dependent pathway
    • Suzuki, T., C. Yamashita, R.L. Zemans, N. Briones, A. Van Linden, and G.P. Downey. 2009. Leukocyte elastase induces lung epithelial apoptosis via a PAR-1-, NF-kappaB-, and p53-dependent pathway. Am. J. Respir. Cell Mol. Biol. 41:742-755. http://dx.doi.org/10.1165/rcmb.2008-0157OC
    • (2009) Am. J. Respir. Cell Mol. Biol. , vol.41 , pp. 742-755
    • Suzuki, T.1    Yamashita, C.2    Zemans, R.L.3    Briones, N.4    Van Linden, A.5    Downey, G.P.6
  • 50
    • 33847343549 scopus 로고    scopus 로고
    • Retinoid-related orphan receptor gamma controls immunoglobulin production and Th1/Th2 cytokine balance in the adaptive immune response to allergen
    • Tilley, S.L., M. Jaradat, C. Stapleton, D. Dixon, X. Hua, C.J. Erikson, J.G. McCaskill, K.D. Chason, G. Liao, L. Jania, et al. 2007. Retinoid-related orphan receptor gamma controls immunoglobulin production and Th1/Th2 cytokine balance in the adaptive immune response to allergen. J. Immunol. 178:3208-3218.
    • (2007) J. Immunol. , vol.178 , pp. 3208-3218
    • Tilley, S.L.1    Jaradat, M.2    Stapleton, C.3    Dixon, D.4    Hua, X.5    Erikson, C.J.6    McCaskill, J.G.7    Chason, K.D.8    Liao, G.9    Jania, L.10
  • 52
    • 21644454525 scopus 로고    scopus 로고
    • Influenza virus infection increases p53 activity: role of p53 in cell death and viral replication
    • Turpin, E., K. Luke, J. Jones, T. Tumpey, K. Konan, and S. Schultz-Cherry. 2005. Influenza virus infection increases p53 activity: role of p53 in cell death and viral replication. J. Virol. 79:8802-8811. http://dx.doi.org/10.1128/JVI.79.14.8802-8811.2005
    • (2005) J. Virol. , vol.79 , pp. 8802-8811
    • Turpin, E.1    Luke, K.2    Jones, J.3    Tumpey, T.4    Konan, K.5    Schultz-Cherry, S.6
  • 54
    • 65349103899 scopus 로고    scopus 로고
    • Blinded by the light: The growing complexity of p53
    • Vousden, K.H., and C. Prives. 2009. Blinded by the light: The growing complexity of p53. Cell. 137:413-431. http://dx.doi.org/10.1016/j.cell.2009.04.037
    • (2009) Cell. , vol.137 , pp. 413-431
    • Vousden, K.H.1    Prives, C.2
  • 56
    • 58149196248 scopus 로고    scopus 로고
    • Diesel exhaust particles induce apoptosis via p53 and Mdm2 in J774A.1 macrophage cell line
    • Yun, Y.P., J.Y. Lee, E.K. Ahn, K.H. Lee, H.K. Yoon, and Y. Lim. 2009. Diesel exhaust particles induce apoptosis via p53 and Mdm2 in J774A.1 macrophage cell line. Toxicol. In Vitro. 23:21-28. http://dx.doi.org/10.1016/j.tiv.2008.09.018
    • (2009) Toxicol. In Vitro. , vol.23 , pp. 21-28
    • Yun, Y.P.1    Lee, J.Y.2    Ahn, E.K.3    Lee, K.H.4    Yoon, H.K.5    Lim, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.