Loss of p53 in stromal fibroblasts promotes epithelial cell invasion through redox-mediated ICAM1 signal

Free Radical Biology and Medicine

Volumn 58, Issue , 2013, Pages 1-13

  Trachootham, Dunyaporn ^a,b   Chen, Gang ^b   Zhang, Wan ^b,c   Lu, Weiqin ^b   Zhang, Hui ^b,d   Liu, Jinsong ^b   Huang, Peng ^b  

^a THAMMASAT UNIVERSITY   (Thailand)

^b UNIVERSITY OF TEXAS   (United States)

^c NANCHANG UNIVERSITY   (China)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Endothelial NO synthase; Fibroblast; Free radicals; ICAM1; Invasion; p53; Reactive nitrogen species

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; PROTEIN P53; REACTIVE NITROGEN SPECIES; SMALL INTERFERING RNA;

ARTICLE; CELL INVASION; CYTOKINE RELEASE; DNA DAMAGE; EPITHELIUM CELL; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STROMA; TUMOR MICROENVIRONMENT;

CELL TRANSFORMATION, NEOPLASTIC; DNA DAMAGE; EPITHELIAL CELLS; FEMALE; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; NEOPLASM INVASIVENESS; NITRIC OXIDE SYNTHASE TYPE III; OVARY; OXIDATION-REDUCTION; REACTIVE NITROGEN SPECIES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STROMAL CELLS; TUMOR MICROENVIRONMENT; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84875977517     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.01.011     Document Type: Article

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