Involvement of pelvic inflammation-related mismatch repair abnormalities and microsatellite instability in the malignant transformation of ovarian endometriosis

Human Pathology

Volumn 43, Issue 11, 2012, Pages 1964-1972

  Fuseya, Chiho ^a   Horiuchi, Akiko ^a   Hayashi, Akiko ^a   Suzuki, Akihisa ^a   Miyamoto, Tsutomu ^a   Hayashi, Takuma ^b   Shiozawa, Tanri ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

CRP; Endometriosis; Malignant transformation; MMR expression; MSI

Indexed keywords

C REACTIVE PROTEIN; MISMATCH REPAIR PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN MLH1; PROTEIN MSH2;

ARTICLE; BLOOD SAMPLING; CANCER PATIENT; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE ASSOCIATION; ENDOMETRIOSIS; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENE MUTATION; GENETIC ANALYSIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; NUCLEOTIDE SEQUENCE; OVARY ADENOCARCINOMA; OVARY CARCINOMA; OVARY DISEASE; OVARY ENDOMETRIOSIS; PELVIC INFLAMMATORY DISEASE; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RISK FACTOR; TISSUE SECTION; TUMOR LOCALIZATION; TUMOR VOLUME;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BRAIN NEOPLASMS; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; CYSTADENOCARCINOMA, SEROUS; DISEASE PROGRESSION; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; ENDOMETRIOSIS; FEMALE; HUMANS; MICROSATELLITE INSTABILITY; NEOPLASM PROTEINS; NEOPLASTIC SYNDROMES, HEREDITARY; NUCLEAR PROTEINS; OVARIAN NEOPLASMS; PELVIC INFLAMMATORY DISEASE; POINT MUTATION; PTEN PHOSPHOHYDROLASE;

EID: 84867861575     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2012.02.005     Document Type: Article

References (35)

1. D.L. Olive, S.R. Lindheim, and E.A. Pritts Endometriosis and infertility: what do we do for each stage? Curr Womens Health Rep 3 2003 389 394
2. J.A. Sampson Endometrial carcinoma of the ovary, arising in endometrial tissue in that organ Arch Surg 10 1925 1 72
3. S. Ogawa, T. Kaku, and S. Amada Ovarian endometriosis associated with ovarian carcinoma: a clinicopathological and immunohistochemical study Gynecol Oncol 77 2000 298 304
4. L.A. Brinton, E.J. Lamb, and K.S. Moghissi Ovarian cancer risk associated with varying causes of infertility Fertil Steril 82 2004 405 414
5. C. Borgfeldt, and E. Andolf Cancer risk after hospital discharge diagnosis of benign ovarian cysts and endometriosis Acta Obstet Gynecol Scand 83 2004 395 400
6. H. Kobayashi, K. Sumimoto, and N. Moniwa Risk of developing ovarian cancer among women with ovarian endometrioma: a cohort study in Shizuoka, Japan Int J Gynecol Cancer 17 2007 37 43
7. A. Melin, P. Sparén, I. Persson, and A. Bergqvist Endometriosis and the risk of cancer with special emphasis on ovarian cancer Hum Reprod 21 2006 1237 1242
8. L.A. Brinton, G. Gridley, I. Persson, J. Baron, and A. Bergqvist Cancer risk after a hospital discharge diagnosis of endometriosis Am J Obstet Gynecol 176 1997 572 579
9. J. Eisermann, M.J. Gast, J. Pineda, R.R. Odem, and J.L. Collins Tumor necrosis factor in peritoneal fluid of women undergoing laparoscopic surgery Fertil Steril 50 1988 573 579
10. L.L. Espey Current status of the hypothesis that mammalian ovulation is comparable to an inflammatory reaction Biol Reprod 50 1994 233 238
11. J.S. Fleming, C.R. Beaugié, I. Haviv, G. Chenevix-Trench, and O.L. Tan Incessant ovulation, inflammation and epithelial ovarian carcinogenesis: revisiting old hypotheses Mol Cell Endocrinol 247 2006 4 21
12. F.Z. Bischoff, M. Heard, and J.L. Simpson Somatic DNA alterations in endometriosis: high frequency of chromosome 17 and p53 loss in late-stage endometriosis J Reprod Immunol 55 2002 49 64
13. R. Sáinz de la Cuesta, M. Izquierdo, M. Cañamero, J.J. Granizo, and F. Manzarbeitia Increased prevalence of p53 overexpression from typical endometriosis to atypical endometriosis and ovarian cancer associated with endometriosis Eur J Obstet Gynecol Reprod Biol 113 2004 87 93
14. K. Obata, S.J. Morland, and R.H. Watson Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors Cancer Res 58 1998 2095 2097
15. M. Martini, M. Ciccarone, and G. Garganese Possible involvement of hMLH1, p16(INK4a) and PTEN in the malignant transformation of endometriosis Int J Cancer 102 2002 398 406
16. J. Otsuka, T. Okuda, and A. Sekizawa K-ras mutation may promote carcinogenesis of endometriosis leading to ovarian clear cell carcinoma Med Electron Microsc 37 2004 188 192
17. S. Amemiya, A. Sekizawa, J. Otsuka, T. Tachikawa, H. Saito, and T. Okai Malignant transformation of endometriosis and genetic alterations of K-ras and microsatellite instability Int J Gynaecol Obstet 86 2004 371 376
18. N. Kato, S. Sasou, and T. Motoyama Expression of hepatocyte nuclear factor-1beta (HNF-1beta) in clear cell tumors and endometriosis of the ovary Mod Pathol 19 2006 83 89
19. K.C. Wiegand, S.P. Shah, and O.M. Al-Agha ARID1A mutations in endometriosis-associated ovarian carcinomas N Engl J Med 363 2010 1532 1543
20. S.F. Lax Molecular genetic pathways in various types of endometrial carcinoma: from a phenotypical to a molecular-based classification Virchows Arch 444 2004 213 223
21. T. Kanaya, S. Kyo, Y. Maida, M. Yanaka, M. Nakamura, and M. Inoue Frequent hypermethylation of MLH1 promoter in normal endometrium of patients with endometrial cancers Oncogene 22 2003 2352 2360
22. R.E. Scully, R.H. Young, and P.B. Clement Tumors of the ovary and maldeveloped gonads, fallopian tube, and broad ligament Atlas of tumor pathology, 3rd Series, Fascicle 23 1998 Armed Forces Institute of Pathology Washington, DC 51 168
23. T. Miyamoto, T. Shiozawa, and H. Kashima Estrogen up-regulates mismatch repair activity in normal and malignant endometrial glandular cells Endocrinology 147 2006 4863 4870
24. P. Plevová, E. Sedláková, and J. Zapletalová Expression of the hMLH1 and hMSH2 proteins in normal tissues: relationship to cancer predisposition in hereditary non-polyposis colon cancer Virchows Arch 446 2005 112 119
25. T.T. Nieminen, A. Gylling, and W.M. Abdel-Rahman Molecular analysis of endometrial tumorigenesis: importance of complex hyperplasia regardless of atypia Clin Cancer Res 15 2009 5772 5783
26. M.A. Murphy, and N. Wentzensen Frequency of mismatch repair deficiency in ovarian cancer: a systematic review Int J Cancer 129 2010 1914 1922
27. R. Ali-Fehmi, I. Khalifeh, and S. Bandyopadhyay Patterns of loss of heterozygosity at 10q23.3 and microsatellite instability in endometriosis, atypical endometriosis, and ovarian carcinoma arising in association with endometriosis Int J Gynecol Pathol 25 2006 223 229
28. A. Duval, and R. Hamelin Mutations at coding repeat sequences in mismatch repair-deficient human cancers: toward a new concept of target genes for instability Cancer Res 62 2002 2447 2454
29. M. Kawaguchi, K. Banno, and M. Yanokura Analysis of candidate target genes for mononucleotide repeat mutation in microsatellite instability-high (MSI-H) endometrial cancer Int J Oncol 35 2009 977 982
30. N. Sato, H. Tsunoda, and M. Nishida Loss of heterozygosity on 10q23.3 and mutation of the tumor suppressor gene PTEN in benign endometrial cyst of the ovary: possible sequence progression from benign endometrial cyst to endometrioid carcinoma and clear cell carcinoma of the ovary Cancer Res 60 2000 7052 7056
31. D.M. Dinulescu, T.A. Ince, B.J. Quade, S.A. Shafer, D. Crowley, and T. Jacks Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer Nat Med 11 2005 63 70
32. D.A. Papanicolaou, R.L. Wilder, S.C. Manolagas, and G.P. Chrousos The pathophysiologic roles of interleukin-6 in human disease Ann Intern Med 128 1998 127 137
33. L.B. Meira, J.M. Bugni, and S.L. Green DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice J Clin Invest 118 2008 2516 2525
34. R.B. Ness, and C. Cottreau Possible role of ovarian epithelial inflammation in ovarian cancer J Natl Cancer Inst 91 1999 1459 1467
35. M.A. McSorley, A.J. Alberg, and D.S. Allen C-reactive protein concentrations and subsequent ovarian cancer risk Obstet Gynecol 109 2007 933 941