Nuclear factor-κB, p53, and mitochondria: Regulation of cellular metabolism and the Warburg effect

Trends in Biochemical Sciences

Volumn 37, Issue 8, 2012, Pages 317-324

  Johnson, Renée F ^a   Perkins, Neil D ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 3; GLUCOSE TRANSPORTER 4; HEXOKINASE 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; HYPOXIA INDUCIBLE FACTOR; I KAPPA B ALPHA; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MALATE DEHYDROGENASE; METFORMIN; MITOCHONDRIAL DNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHOGLYCERATE MUTASE; PROTEIN KINASE B; PROTEIN MDM2; PROTEIN P53; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; RIBOSOME RNA; STAT3 PROTEIN; TRANSCRIPTION FACTOR NRF1; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR RELB; TRANSFER RNA; UNINDEXED DRUG;

CANCER INHIBITION; CARCINOGENESIS; CELL METABOLISM; ENERGY METABOLISM; GENE EXPRESSION REGULATION; GLYCOLYSIS; HUMAN; MITOCHONDRION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; TUMOR CELL; WARBURG EFFECT;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOLYSIS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; MITOCHONDRIA; NF-KAPPA B; OXIDATIVE PHOSPHORYLATION; PROTEIN TRANSPORT; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84864292987     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibs.2012.04.002     Document Type: Review

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