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Volumn 13, Issue 7, 2014, Pages 1179-1190

Biodegradable poly(D,L-lactic-co-glycolic acid)-based micro/nanoparticles for sustained release of protein drugs - A review

Author keywords

Microparticles; Nanoparticles; Poly(D, L lactic co glycolic acid); Protein instability; Protein peptides; Sustained release

Indexed keywords

ANDOSTATIN LAR; BOVINE SERUM ALBUMIN; BUSERELIN ACETATE; DICHLOROMETHANE; DIDODECYLDIMETHYLAMMONIUM BROMIDE; DODECYL SULFATE SODIUM; HUMAN GROWTH HORMONE; HYDROXYPROPYLMETHYLCELLULOSE PHTHALATE; INSULIN; LEUPRORELIN; MINOCYCLINE; NANOPARTICLE; OCTREOTIDE; PEPTIDES AND PROTEINS; POLYESTER; POLYGLACTIN; POLYLACTIDE; POLYVINYL ALCOHOL; RECOMBINANT ERYTHROPOIETIN; RISPERIDONE; TRIPTORELIN; UNCLASSIFIED DRUG;

EID: 84905239233     PISSN: 15965996     EISSN: 15969827     Source Type: Journal    
DOI: 10.4314/tjpr.v13i7.24     Document Type: Review
Times cited : (69)

References (78)
  • 2
    • 0035914233 scopus 로고    scopus 로고
    • Non-aqueous encapsulation of excipient-stabilized spray-freeze dried BSA into poly(lactide-co-glycolide) microspheres results in release of native protein
    • Karen GC, Ann MS, Juan CA, Patricia DJ, Henry RC, Carlos JB, Kai G. Non-aqueous encapsulation of excipient-stabilized spray-freeze dried BSA into poly(lactide-co-glycolide) microspheres results in release of native protein. J. Control. Release 2001; 76: 199-208.
    • (2001) J. Control. Release , vol.76 , pp. 199-208
    • Karen, G.C.1    Ann, M.S.2    Juan, C.A.3    Patricia, D.J.4    Henry, R.C.5    Carlos, J.B.6    Kai, G.7
  • 3
    • 0031837756 scopus 로고    scopus 로고
    • Bovine serum albumin loaded poly(lactide-co-glycolide) microspheres: The influence of polymer purity on particle characteristics
    • Bittner B, Ronneberger B, Zange R, Volland C, Anderson JM, Kissel T. Bovine serum albumin loaded poly(lactide-co-glycolide) microspheres: the influence of polymer purity on particle characteristics. J. Microencapsul. 1998; 15: 495-514.
    • (1998) J. Microencapsul. , vol.15 , pp. 495-514
    • Bittner, B.1    Ronneberger, B.2    Zange, R.3    Volland, C.4    Anderson, J.M.5    Kissel, T.6
  • 4
    • 0031850896 scopus 로고    scopus 로고
    • Improving stability&release kinetics of microencapsulated tetanus toxoid by coencapsulation of additives
    • Johansen P, Men Y, Audran R, Corradin G, Merkle HP, Gander B. Improving stability&release kinetics of microencapsulated tetanus toxoid by coencapsulation of additives. Pharm. Res. 1998; 15: 1103-1110.
    • (1998) Pharm. Res. , vol.15 , pp. 1103-1110
    • Johansen, P.1    Men, Y.2    Audran, R.3    Corradin, G.4    Merkle, H.P.5    Gander, B.6
  • 5
    • 0030061447 scopus 로고    scopus 로고
    • Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid /polyglycolic acid copolymers
    • Athanasiou KA, Niederauer GG, Agrawal CM. Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid /polyglycolic acid copolymers. Biomaterials 1996; 17: 93-102.
    • (1996) Biomaterials , vol.17 , pp. 93-102
    • Athanasiou, K.A.1    Niederauer, G.G.2    Agrawal, C.M.3
  • 6
    • 0030033719 scopus 로고    scopus 로고
    • Mechanisms of polymer degradation and erosion
    • Göpferich A. Mechanisms of polymer degradation and erosion. Biomaterials 1996; 17: 103-114.
    • (1996) Biomaterials , vol.17 , pp. 103-114
    • Göpferich, A.1
  • 7
    • 0018737940 scopus 로고
    • Biodegradable polymers for use in surgery. Polyglycolic/poly(lactic acid) homo-and copolymers
    • Gilding DK, Reed AM. Biodegradable polymers for use in surgery. Polyglycolic/poly(lactic acid) homo-and copolymers: 1. Polymer 1979; 20: 1459-1464.
    • (1979) Polymer , vol.20 , pp. 1459-1464
    • Gilding, D.K.1    Reed, A.M.2
  • 8
    • 0031752709 scopus 로고    scopus 로고
    • Protein delivery from poly(lactic-coglycolic acid)biodegradable microspheres: Release kinetics and stability issues
    • Crotts G, Tae GP. Protein delivery from poly(lactic-coglycolic acid)biodegradable microspheres: release kinetics and stability issues. J. Microencapsul. 1998; 15: 699-713.
    • (1998) J. Microencapsul. , vol.15 , pp. 699-713
    • Crotts, G.1    Tae, G.P.2
  • 9
    • 33846641249 scopus 로고    scopus 로고
    • Stabilization of protein encapsulated in poly(lactide-co-glycolide) microspheres by novel viscous S/W/O/W method
    • Eun SL, Min JK, Hyeok L, Jung JK. Stabilization of protein encapsulated in poly(lactide-co-glycolide) microspheres by novel viscous S/W/O/W method. Int. J. Pharm. 2007; 331: 27-37.
    • (2007) Int. J. Pharm. , vol.331 , pp. 27-37
    • Eun, S.L.1    Min, J.K.2    Hyeok, L.3    Jung, J.K.4
  • 10
    • 0032078351 scopus 로고    scopus 로고
    • Protein encapsulation and release from poly(lactide-co-glycolide) microspheres: Effect of the protein and polymer properties and of the coencapsulation of surfactants
    • Dolores B, Mari{dotless}a JA. Protein encapsulation and release from poly(lactide-co-glycolide) microspheres: effect of the protein and polymer properties and of the coencapsulation of surfactants. Eur. J. Pharm. Biopharm. 1998; 45: 285-294.
    • (1998) Eur. J. Pharm. Biopharm. , vol.45 , pp. 285-294
    • Dolores, B.1    Maria, J.A.2
  • 11
    • 33745919229 scopus 로고    scopus 로고
    • BSA degradation under acidic conditions: A model of protein instability during release from PLGA delivery systems
    • Tia E, Jichao K, Steven PS, John FC. BSA degradation under acidic conditions: a model of protein instability during release from PLGA delivery systems. J. Pharm. Sci. 2006; 95: 1626-1639.
    • (2006) J. Pharm. Sci. , vol.95 , pp. 1626-1639
    • Tia, E.1    Jichao, K.2    Steven, P.S.3    John, F.C.4
  • 12
    • 0036027563 scopus 로고    scopus 로고
    • Comparison of the effects of Mg(OH)2 and sucrose on the stability of bovine serum albumin encapsulated in injectable poly(D, L-lactide-co-glycolide) implants
    • Jichao K, Steven PS. Comparison of the effects of Mg(OH)2 and sucrose on the stability of bovine serum albumin encapsulated in injectable poly(D, L-lactide-co-glycolide) implants. Biomaterials. 2002; 23: 239-245
    • (2002) Biomaterials. , vol.23 , pp. 239-245
    • Jichao, K.1    Steven, P.S.2
  • 14
    • 0023943907 scopus 로고
    • Controlled-release of leuprolide acetate from polylactic acid or copoly(lactic/glycolic) acid microcapsules: Influence of molecular weight and copolymer ratio of polymer
    • Ogawa Y, Yamamoto M, Takada S, Okada H, Shimamoto T. Controlled-release of leuprolide acetate from polylactic acid or copoly(lactic/glycolic) acid microcapsules: influence of molecular weight and copolymer ratio of polymer. Chem. Pharm. Bull. 1988; 36: 1502-1507.
    • (1988) Chem. Pharm. Bull. , vol.36 , pp. 1502-1507
    • Ogawa, Y.1    Yamamoto, M.2    Takada, S.3    Okada, H.4    Shimamoto, T.5
  • 15
    • 20144367507 scopus 로고    scopus 로고
    • Poly(D, L-lactide-coglycolide) protein-loaded nanoparticles prepared by the double emulsion method-processing and formulation issues for enhanced entrapment efficiency
    • Bilati U, Allemann E, Doelker E. Poly(D, L-lactide-coglycolide) protein-loaded nanoparticles prepared by the double emulsion method-processing and formulation issues for enhanced entrapment efficiency. J. Microencapsul. 2005; 22: 205-214.
    • (2005) J. Microencapsul. , vol.22 , pp. 205-214
    • Bilati, U.1    Allemann, E.2    Doelker, E.3
  • 16
    • 0031575558 scopus 로고    scopus 로고
    • Stability and release of bovine serum albumin encapsulated within poly(D, L-lactide-coglycolide) microparticles
    • Crotts G, Tae GP. Stability and release of bovine serum albumin encapsulated within poly(D, L-lactide-coglycolide) microparticles. J. Control. Release. 1997; 44: 123-134.
    • (1997) J. Control. Release. , vol.44 , pp. 123-134
    • Crotts, G.1    Tae, G.P.2
  • 17
    • 0025272779 scopus 로고
    • Microencapsulation using poly (L-lactic acid) III: Effect of polymer molecular weight on the microcapsule properties
    • Jalil R, Nixon JR. Microencapsulation using poly (L-lactic acid) III: Effect of polymer molecular weight on the microcapsule properties. J. Microencapsul. 1990; 7: 41-52.
    • (1990) J. Microencapsul. , vol.7 , pp. 41-52
    • Jalil, R.1    Nixon, J.R.2
  • 18
    • 0028319146 scopus 로고
    • Degradation of poly(D, L-lactic acid) microspheres: Effect of molecular weight
    • Park TG. Degradation of poly(D, L-lactic acid) microspheres: effect of molecular weight. J. Control. Release 1994; 30: 161-173.
    • (1994) J. Control. Release , vol.30 , pp. 161-173
    • Park, T.G.1
  • 19
    • 0032976670 scopus 로고    scopus 로고
    • Hydrolytic degradation characteristics of aliphatic polyesters derived from lactic and glycolic acids
    • Li S. Hydrolytic degradation characteristics of aliphatic polyesters derived from lactic and glycolic acids. J. Biomed. Mater. Res. 1999; 48: 342-353.
    • (1999) J. Biomed. Mater. Res. , vol.48 , pp. 342-353
    • Li, S.1
  • 20
    • 0035845758 scopus 로고    scopus 로고
    • Hydrophilic poly(DL-lactide-co-glycolide) microspheres for the delivery of DNA to humanderived macrophages and dendritic cells
    • Walter E, Dreher D, Kok M, Thiele L, Kiama SG, Gehr P, Merkle HP. Hydrophilic poly(DL-lactide-co-glycolide) microspheres for the delivery of DNA to humanderived macrophages and dendritic cells. J. Control. Release 2001; 76: 149-168.
    • (2001) J. Control. Release , vol.76 , pp. 149-168
    • Walter, E.1    Dreher, D.2    Kok, M.3    Thiele, L.4    Kiama, S.G.5    Gehr, P.6    Merkle, H.P.7
  • 21
    • 29244460647 scopus 로고    scopus 로고
    • Influence of the poly(lactide-coglycolide) type on the leuprolide release from in situ forming microparticle systems
    • Luan X, Bodmeier R. Influence of the poly(lactide-coglycolide) type on the leuprolide release from in situ forming microparticle systems. J. Control. Release 2006; 110: 266-272.
    • (2006) J. Control. Release , vol.110 , pp. 266-272
    • Luan, X.1    Bodmeier, R.2
  • 22
    • 0022039832 scopus 로고
    • Biodegradation of and tissue reaction to 50:50 poly(d, l-lactide-co-glycolide) microcapsules
    • Visscher GE, Robison RL, Mauling HV, et al. Biodegradation of and tissue reaction to 50:50 poly(d, l-lactide-co-glycolide) microcapsules. J. Biomed. Mater. Res. 1985; 19: 349-365.
    • (1985) J. Biomed. Mater. Res. , vol.19 , pp. 349-365
    • Visscher, G.E.1    Robison, R.L.2    Mauling, H.V.3
  • 24
    • 0024137697 scopus 로고
    • Thermal characterization of polylactides
    • Jamshidi K, Hyon SH, Ikada Y. Thermal characterization of polylactides. Polymer 1988; 29: 2229-2234.
    • (1988) Polymer , vol.29 , pp. 2229-2234
    • Jamshidi, K.1    Hyon, S.H.2    Ikada, Y.3
  • 25
    • 0037426719 scopus 로고    scopus 로고
    • A novel controlled release formulation for the anticancer drug paclitaxel (Taxol (R): PLGA nanoparticles containing vitamin E TPGS
    • Mu L, Feng SS. A novel controlled release formulation for the anticancer drug paclitaxel (Taxol (R): PLGA nanoparticles containing vitamin E TPGS. J. Control. Release 2003; 86:33-48.
    • (2003) J. Control. Release , vol.86 , pp. 33-48
    • Mu, L.1    Feng, S.S.2
  • 26
    • 33748062679 scopus 로고    scopus 로고
    • Controlled release of gentamicin from calcium phosphate-Poly(lactic acid-co-glycolic acid) composite bone cement
    • Schnieders J, Gbureck U, Thull R, Kissel T. Controlled release of gentamicin from calcium phosphate-Poly(lactic acid-co-glycolic acid) composite bone cement. Biomaterials 2006; 27: 4239-4249.
    • (2006) Biomaterials , vol.27 , pp. 4239-4249
    • Schnieders, J.1    Gbureck, U.2    Thull, R.3    Kissel, T.4
  • 27
    • 0033968809 scopus 로고    scopus 로고
    • Gentamicin encapsulation in PLA/PLGA microspheres in view of treating Brucella infections
    • Prior S, Gamazo C, Irache JM., Merkle HP, Gander B. Gentamicin encapsulation in PLA/PLGA microspheres in view of treating Brucella infections. Int. J. Pharm. 2000; 196: 115-125.
    • (2000) Int. J. Pharm. , vol.196 , pp. 115-125
    • Prior, S.1    Gamazo, C.2    Irache, J.M.3    Merkle, H.P.4    Gander, B.5
  • 28
    • 21244502566 scopus 로고    scopus 로고
    • Gentamicinloaded microspheres for treatment of experimental Brucella abortus infection in mice
    • Prior S, Gander B, Irache JM, Gamazo C. Gentamicinloaded microspheres for treatment of experimental Brucella abortus infection in mice. J Antimicrob Chemother 2005; 55: 1032-1036.
    • (2005) J Antimicrob Chemother , vol.55 , pp. 1032-1036
    • Prior, S.1    Gander, B.2    Irache, J.M.3    Gamazo, C.4
  • 30
    • 0343907187 scopus 로고    scopus 로고
    • One-and three-month release injectable microspheres of the LH-RH superagonist leuprorelin acetate
    • Okada H. One-and three-month release injectable microspheres of the LH-RH superagonist leuprorelin acetate. Adv. Drug Deliv. Rev. 1997; 28: 43-70.
    • (1997) Adv. Drug Deliv. Rev. , vol.28 , pp. 43-70
    • Okada, H.1
  • 31
    • 19344374176 scopus 로고    scopus 로고
    • Impurity formation studies with peptide-loaded polymeric microspheres: Part I. In vivo evaluation
    • Murty SB, Thanoo BC, Wei Q, DeLuca PP. Impurity formation studies with peptide-loaded polymeric microspheres: Part I. In vivo evaluation. Int. J. Pharm. 2005; 297: 50-61.
    • (2005) Int. J. Pharm. , vol.297 , pp. 50-61
    • Murty, S.B.1    Thanoo, B.C.2    Wei, Q.3    DeLuca, P.P.4
  • 32
    • 0037133127 scopus 로고    scopus 로고
    • Assessment of protein release kinetics, stability and protein polymer interaction of lysozyme encapsulated poly(D, L-lactide-co-glycolide) microspheres
    • Jiang G, Byung HW, Feirong K, Jagdish S, Patrick PD. Assessment of protein release kinetics, stability and protein polymer interaction of lysozyme encapsulated poly(D, L-lactide-co-glycolide) microspheres. J. Control. Release 2002; 79: 137-145.
    • (2002) J. Control. Release , vol.79 , pp. 137-145
    • Jiang, G.1    Byung, H.W.2    Feirong, K.3    Jagdish, S.4    Patrick, P.D.5
  • 33
    • 6344276550 scopus 로고    scopus 로고
    • Poly(lactide-co-glycolide) microparticles as systems for controlled release of proteins-Preparation and characterization
    • Aleksandra P, Katerina G, Kristina M, Marija G, Maja S, Emilija IJ, Maja C. Poly(lactide-co-glycolide) microparticles as systems for controlled release of proteins-Preparation and characterization. Acta Pharm. 2004; 54: 215-229.
    • (2004) Acta Pharm. , vol.54 , pp. 215-229
    • Aleksandra, P.1    Katerina, G.2    Kristina, M.3    Marija, G.4    Maja, S.5    Emilija, I.J.6    Maja, C.7
  • 34
    • 59849119650 scopus 로고    scopus 로고
    • Insulin loaded PLGA microspheres:Effect of zinc salts on encapsulation, release, and stability
    • Chandrasekar M, Jagdish S. Insulin loaded PLGA microspheres:Effect of zinc salts on encapsulation, release, and stability. J. Pharm. Sci. 2009; 98: 529-542.
    • (2009) J. Pharm. Sci. , vol.98 , pp. 529-542
    • Chandrasekar, M.1    Jagdish, S.2
  • 36
    • 77955575347 scopus 로고    scopus 로고
    • Synthesis and organocatalytic ring-opening polymerization of cyclic esters derived from L-malic acid
    • Pounder RJ, Dove AP. Synthesis and organocatalytic ring-opening polymerization of cyclic esters derived from L-malic acid. Biomacromolecules 2010; 11: 1930-1939.
    • (2010) Biomacromolecules , vol.11 , pp. 1930-1939
    • Pounder, R.J.1    Dove, A.P.2
  • 37
    • 0032966859 scopus 로고    scopus 로고
    • Synthesis and properties of malic acid-containing functional polymers
    • Yamaoka T, Hotta Y, Kobayashi K, Kimura Y. Synthesis and properties of malic acid-containing functional polymers. Int. J. Biol. Macromol. 1999; 25: 265-271.
    • (1999) Int. J. Biol. Macromol. , vol.25 , pp. 265-271
    • Yamaoka, T.1    Hotta, Y.2    Kobayashi, K.3    Kimura, Y.4
  • 39
    • 34948881276 scopus 로고    scopus 로고
    • In vitro hydrolytic degradation of hydroxyl-functionalized poly(α-hydroxy acid)s
    • Leemhuis M, Kruijtzer JAW, Nostrum CF, Hennink WE. In vitro hydrolytic degradation of hydroxyl-functionalized poly(α-hydroxy acid)s. Biomacromolecules 2007; 8: 2943-2949.
    • (2007) Biomacromolecules , vol.8 , pp. 2943-2949
    • Leemhuis, M.1    Kruijtzer, J.A.W.2    Nostrum, C.F.3    Hennink, W.E.4
  • 40
    • 0026633220 scopus 로고
    • Preparation of poly(DL-lactide/glycolide) nanoparticles of controlled particle size distribution:Application of experimental designs
    • Julienne MC, Alonso MJ, Gomez Amoza JL, Benoit JP. Preparation of poly(DL-lactide/glycolide) nanoparticles of controlled particle size distribution:application of experimental designs. Drug Dev. Ind. Pharm. 1992; 18: 1063-1077.
    • (1992) Drug Dev. Ind. Pharm. , vol.18 , pp. 1063-1077
    • Julienne, M.C.1    Alonso, M.J.2    Gomez Amoza, J.L.3    Benoit, J.P.4
  • 41
    • 0024457576 scopus 로고
    • Nanocapsule formation by interfacial polymer deposition following solvent displacement
    • Fessi H, Puisieux F, Devissaguet JP, Ammoury N, Benita S. Nanocapsule formation by interfacial polymer deposition following solvent displacement. Int. J. Pharm. 1989; 55: R1-R4.
    • (1989) Int. J. Pharm. , vol.55
    • Fessi, H.1    Puisieux, F.2    Devissaguet, J.P.3    Ammoury, N.4    Benita, S.5
  • 42
    • 0030575715 scopus 로고    scopus 로고
    • Influence of stabilizing agents and preparative variables on the formation of poly(d, l-lactic acid) nanoparticles by an emulsification-diffusion technique
    • Quintanar-Guerrero D, Fessi H, All'emann E, et al. Influence of stabilizing agents and preparative variables on the formation of poly(d, l-lactic acid) nanoparticles by an emulsification-diffusion technique. Int. J. Pharm. 1996; 143: 133-141.
    • (1996) Int. J. Pharm. , vol.143 , pp. 133-141
    • Quintanar-Guerrero, D.1    Fessi, H.2    All'emann, E.3
  • 43
    • 0027133051 scopus 로고
    • In vitro extended-release properties of drug-loaded poly(DLlactic acid) nanoparticles produced by a salting-out procedure
    • Allemann E, Leroux JC, Gurny R, Doelker E. In vitro extended-release properties of drug-loaded poly(DLlactic acid) nanoparticles produced by a salting-out procedure. Pharm. Res. 1993; 10: 1732-1737.
    • (1993) Pharm. Res. , vol.10 , pp. 1732-1737
    • Allemann, E.1    Leroux, J.C.2    Gurny, R.3    Doelker, E.4
  • 44
    • 0034601237 scopus 로고    scopus 로고
    • Sulfobutylated poly(vinyl alcohol)-graft-poly(lactide-co-glycolide)s facilitate the preparation of small negatively charged biodegradable nanospheres
    • Jung T, Breitenbach A, Kissel T. Sulfobutylated poly(vinyl alcohol)-graft-poly(lactide-co-glycolide)s facilitate the preparation of small negatively charged biodegradable nanospheres. J. Control. Release 2000; 67: 157-169.
    • (2000) J. Control. Release , vol.67 , pp. 157-169
    • Jung, T.1    Breitenbach, A.2    Kissel, T.3
  • 45
    • 34447623755 scopus 로고    scopus 로고
    • Preparation, characterisation and maintenance of drug efficacy of doxorubicin-loaded human serum albumin (HSA) nanoparticles
    • Dreis S, Rothweiler F, Michaelis M, Cinatl J, Kreuter J, Langer K. Preparation, characterisation and maintenance of drug efficacy of doxorubicin-loaded human serum albumin (HSA) nanoparticles. Int. J. Pharm. 2007; 341: 207-214.
    • (2007) Int. J. Pharm. , vol.341 , pp. 207-214
    • Dreis, S.1    Rothweiler, F.2    Michaelis, M.3    Cinatl, J.4    Kreuter, J.5    Langer, K.6
  • 46
    • 0037028031 scopus 로고    scopus 로고
    • Effects of material hydrophobicity on physical properties of polymeric microspheres formed by double emulsion process
    • Ruan G, Feng SS, Li QT. Effects of material hydrophobicity on physical properties of polymeric microspheres formed by double emulsion process. J. Control. Release 2002; 84: 151-160.
    • (2002) J. Control. Release , vol.84 , pp. 151-160
    • Ruan, G.1    Feng, S.S.2    Li, Q.T.3
  • 47
    • 32244438967 scopus 로고    scopus 로고
    • Design of estradiol loaded PLGA nanoparticle formulations:A potential oral delivery system for hormone theraphy
    • Hariharan S, Bhardwaj V, Bala I, Sitterberg J, Bakowsky U, Kumar M. Design of estradiol loaded PLGA nanoparticle formulations:A potential oral delivery system for hormone theraphy. Pharm. Res. 2006; 23: 184-195.
    • (2006) Pharm. Res. , vol.23 , pp. 184-195
    • Hariharan, S.1    Bhardwaj, V.2    Bala, I.3    Sitterberg, J.4    Bakowsky, U.5    Kumar, M.6
  • 48
    • 33947301446 scopus 로고    scopus 로고
    • Size control of poly(d, l-lactide-co-glycolide) and poly(d, l-lactide-coglycolide)-magnetite nanoparticles synthesized by emulsion evaporation technique
    • Astete CE, Kumar CSSR, Sabliov CM. Size control of poly(d, l-lactide-co-glycolide) and poly(d, l-lactide-coglycolide)-magnetite nanoparticles synthesized by emulsion evaporation technique. Colloids Surf. A Physicochem. Eng. Asp. 2007; 299: 209-216.
    • (2007) Colloids Surf. A Physicochem. Eng. Asp. , vol.299 , pp. 209-216
    • Astete, C.E.1    Kumar, C.S.S.R.2    Sabliov, C.M.3
  • 49
    • 43249104222 scopus 로고    scopus 로고
    • PLGA nanoparticles for oral delivery of hydrophobic drugs:Influence of organic solvent on nanoparticle formation and release behavior in vitro and in vivo using estradiol as a model drug
    • Sahana DK, Mittal G, Bhardwaj V, Kuamr M. PLGA nanoparticles for oral delivery of hydrophobic drugs:Influence of organic solvent on nanoparticle formation and release behavior in vitro and in vivo using estradiol as a model drug. J. Pharm. Sci. 2008; 97: 1530-1542.
    • (2008) J. Pharm. Sci. , vol.97 , pp. 1530-1542
    • Sahana, D.K.1    Mittal, G.2    Bhardwaj, V.3    Kuamr, M.4
  • 50
    • 33846410672 scopus 로고    scopus 로고
    • Folate-decorated poly(lactide-co-glycolide)-vitamin E TPGS nanoparticles for targeted drug delivery
    • Zhang ZP, Lee SH, Feng SS. Folate-decorated poly(lactide-co-glycolide)-vitamin E TPGS nanoparticles for targeted drug delivery. Biomaterials; 2007; 28: 1889-1899.
    • (2007) Biomaterials , vol.28 , pp. 1889-1899
    • Zhang, Z.P.1    Lee, S.H.2    Feng, S.S.3
  • 51
    • 0035255916 scopus 로고    scopus 로고
    • Morphology, drug distribution, and in vitro release profiles of biodegradable polymeric microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method
    • Yang YY, Chung TS, Ng NP. Morphology, drug distribution, and in vitro release profiles of biodegradable polymeric microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method. Biomaterials 2001; 22: 231-241.
    • (2001) Biomaterials , vol.22 , pp. 231-241
    • Yang, Y.Y.1    Chung, T.S.2    Ng, N.P.3
  • 52
    • 0028935777 scopus 로고
    • Biodegradable microcapsules prepared by a W/O/W technique: Effects of shear force to make a primary W/O emulsion on their morphology and protein release
    • Sah HK, Toddywala R, Chien YW. Biodegradable microcapsules prepared by a W/O/W technique: effects of shear force to make a primary W/O emulsion on their morphology and protein release. J. Microencapsul. 1995; 12: 59-69.
    • (1995) J. Microencapsul. , vol.12 , pp. 59-69
    • Sah, H.K.1    Toddywala, R.2    Chien, Y.W.3
  • 53
    • 0034601882 scopus 로고    scopus 로고
    • Effect of preparation temperature on the characteristics and release profiles of PLGA microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method
    • Yang YY, Chia HH, Chung TS. Effect of preparation temperature on the characteristics and release profiles of PLGA microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method. J. Control. Release 2000; 69: 81-96.
    • (2000) J. Control. Release , vol.69 , pp. 81-96
    • Yang, Y.Y.1    Chia, H.H.2    Chung, T.S.3
  • 55
    • 0034601661 scopus 로고    scopus 로고
    • The effect of a water/organic solvent interface on the structural stability of lysozyme
    • Weert MVD, Hoechstetter J, Hennink WE, Crommelin DJ. The effect of a water/organic solvent interface on the structural stability of lysozyme. J. Control. Release 2000; 68: 351-359.
    • (2000) J. Control. Release , vol.68 , pp. 351-359
    • Weert, M.V.D.1    Hoechstetter, J.2    Hennink, W.E.3    Crommelin, D.J.4
  • 56
    • 0037436016 scopus 로고    scopus 로고
    • Poly(ethylene glycol) as stabilizer and emulsifying agent: A novel stabilization approach preventing aggregation and inactivation of proteins upon encapsulation in bioerodible polyester microspheres
    • Castellanos IJ, Crespo R, Griebenow K. Poly(ethylene glycol) as stabilizer and emulsifying agent: a novel stabilization approach preventing aggregation and inactivation of proteins upon encapsulation in bioerodible polyester microspheres. J. Control. Release 2003; 88: 135-145.
    • (2003) J. Control. Release , vol.88 , pp. 135-145
    • Castellanos, I.J.1    Crespo, R.2    Griebenow, K.3
  • 57
    • 0742289637 scopus 로고    scopus 로고
    • Stabilization and encapsulation of human immunoglobulin G into biodegradable microspheres
    • Wang J, Chua KM, Wang CH. Stabilization and encapsulation of human immunoglobulin G into biodegradable microspheres. J. Colloid. Interface Sci. 2004; 271: 92-101.
    • (2004) J. Colloid. Interface Sci. , vol.271 , pp. 92-101
    • Wang, J.1    Chua, K.M.2    Wang, C.H.3
  • 58
    • 4143125874 scopus 로고    scopus 로고
    • Poly(lactide-co-glycolide) nanoparticles containing coumarin-6 for suppository delivery: In vitro release profile and in vivo tissue distribution
    • Eley JG, Pujari VD, McLane J. Poly(lactide-co-glycolide) nanoparticles containing coumarin-6 for suppository delivery: in vitro release profile and in vivo tissue distribution. Drug Dlivery 2004; 11: 255-261.
    • (2004) Drug Dlivery , vol.11 , pp. 255-261
    • Eley, J.G.1    Pujari, V.D.2    McLane, J.3
  • 59
    • 38349154138 scopus 로고    scopus 로고
    • Nano/micro technologies for delivering macromolecular therapeutics using poly(D, L-lactideco-glycolide) and its derivatives
    • Raghavendra CM, Ramesh BV, Rangaswamy V, Pradip P, Tejraj MA. Nano/micro technologies for delivering macromolecular therapeutics using poly(D, L-lactideco-glycolide) and its derivatives. J. Control. Release 2008; 125: 193-209.
    • (2008) J. Control. Release , vol.125 , pp. 193-209
    • Raghavendra, C.M.1    Ramesh, B.V.2    Rangaswamy, V.3    Pradip, P.4    Tejraj, M.A.5
  • 60
  • 61
    • 0029859532 scopus 로고    scopus 로고
    • Stable formulations of recombinant human growth hormone and interferon-gamma for microencapsulation in biodegradable microspheres
    • Cleland JL, Jones AJ. Stable formulations of recombinant human growth hormone and interferon-gamma for microencapsulation in biodegradable microspheres. Pharm. Res. 1996; 13: 1464-1475.
    • (1996) Pharm. Res. , vol.13 , pp. 1464-1475
    • Cleland, J.L.1    Jones, A.J.2
  • 62
    • 0031398790 scopus 로고    scopus 로고
    • Microencapsulation of rh-erythropoietin, using biodegradable poly(D, Llactide-co-glycolide): Protein stability and the effects of stabilizing excipients
    • Morlock MK, Winter HG, Kissel T. Microencapsulation of rh-erythropoietin, using biodegradable poly(D, Llactide-co-glycolide): protein stability and the effects of stabilizing excipients. Eur. J. Pharm. Biopharm. 1997; 43: 29-36.
    • (1997) Eur. J. Pharm. Biopharm. , vol.43 , pp. 29-36
    • Morlock, M.K.1    Winter, H.G.2    Kissel, T.3
  • 63
    • 0035858370 scopus 로고    scopus 로고
    • Development of poly(D, Llactide-co-glycolide) microsphere formulations containing recombinant human vascular endothelial growth factor to promote local angiogenesis
    • Cleland JL, Duenas ET, Park A, Daugherty A, Kahn J, Kowalski J, Cuthbertson A. Development of poly(D, Llactide-co-glycolide) microsphere formulations containing recombinant human vascular endothelial growth factor to promote local angiogenesis. J. Control. Release 2001; 72: 13-24.
    • (2001) J. Control. Release , vol.72 , pp. 13-24
    • Cleland, J.L.1    Duenas, E.T.2    Park, A.3    Daugherty, A.4    Kahn, J.5    Kowalski, J.6    Cuthbertson, A.7
  • 64
    • 0035850257 scopus 로고    scopus 로고
    • Pegylation enhances protein stability during encapsulation in PLGA microspheres
    • Manish D, Tae Gwan P. Pegylation enhances protein stability during encapsulation in PLGA microspheres. J. Control. Release 2001; 73: 233-244.
    • (2001) J. Control. Release , vol.73 , pp. 233-244
    • Manish, D.1    Tae Gwan, P.2
  • 65
    • 80051784753 scopus 로고    scopus 로고
    • Stabilization and encapsulation of recombinant human erythropoietin into PLGA microspheres using human serum albumin as a stabilizer
    • Jintian H, Meiyan F, Xianglian Z, Shufen M, Yang J, Ying W, Hongxia Z. Stabilization and encapsulation of recombinant human erythropoietin into PLGA microspheres using human serum albumin as a stabilizer. Int. J. Pharm. 2011; 416: 69-76.
    • (2011) Int. J. Pharm. , vol.416 , pp. 69-76
    • Jintian, H.1    Meiyan, F.2    Xianglian, Z.3    Shufen, M.4    Yang, J.5    Ying, W.6    Hongxia, Z.7
  • 66
    • 65949087875 scopus 로고    scopus 로고
    • A novel approach to prepare insulin-loaded poly(lactic-coglycolic acid) microcapsules and the protein stability study
    • Emami J, Hamishehkar H, Najafabadi AR, Gilani K, Minaiyan M, Mahdavi H, Nokhodchi A. A novel approach to prepare insulin-loaded poly(lactic-coglycolic acid) microcapsules and the protein stability study. J. Pharm. Sci. 2009; 98: 1712-1731.
    • (2009) J. Pharm. Sci. , vol.98 , pp. 1712-1731
    • Emami, J.1    Hamishehkar, H.2    Najafabadi, A.R.3    Gilani, K.4    Minaiyan, M.5    Mahdavi, H.6    Nokhodchi, A.7
  • 67
    • 0033986610 scopus 로고    scopus 로고
    • Stabilisation of proteins encapsulated in injectable poly(lactide-coglycolide) polymers
    • Zhu G, Hallery SR, Schwendemem SP. Stabilisation of proteins encapsulated in injectable poly(lactide-coglycolide) polymers. Nat. Biotech. 2000; 18: 52-57.
    • (2000) Nat. Biotech. , vol.18 , pp. 52-57
    • Zhu, G.1    Hallery, S.R.2    Schwendemem, S.P.3
  • 68
    • 77955439513 scopus 로고    scopus 로고
    • Controlled release of bioactive recombinant human growth hormone from PLGA microparticles
    • Rafi M, Surinder MS, Vibhu K, Anish CK, Amulya KP. Controlled release of bioactive recombinant human growth hormone from PLGA microparticles. J. Microencapsul. 2010; 27: 552-560.
    • (2010) J. Microencapsul. , vol.27 , pp. 552-560
    • Rafi, M.1    Surinder, M.S.2    Vibhu, K.3    Anish, C.K.4    Amulya, K.P.5
  • 69
    • 2142768756 scopus 로고    scopus 로고
    • Importance of single or blended polymer types for controlled in vitro release and plasma levels of a somatostatin analogue entrapped in PLA/PLGA microspheres
    • Blanco-Prieto MJ, Campanero MA, Besseghir K, Heimgatner F, Gander B. Importance of single or blended polymer types for controlled in vitro release and plasma levels of a somatostatin analogue entrapped in PLA/PLGA microspheres. J. Control. Release 2004; 96: 437-448.
    • (2004) J. Control. Release , vol.96 , pp. 437-448
    • Blanco-Prieto, M.J.1    Campanero, M.A.2    Besseghir, K.3    Heimgatner, F.4    Gander, B.5
  • 70
    • 0034601108 scopus 로고    scopus 로고
    • Sustained release of recombinant human insulin-like growth factor-I for treatment of diabetes
    • 2000
    • Lam XM, Duenas ET, Daugherty AL, Levin N, Cleland JL. 2000. Sustained release of recombinant human insulin-like growth factor-I for treatment of diabetes. J. Control. Release 2000; 67: 281-292.
    • (2000) J. Control. Release , vol.67 , pp. 281-292
    • Lam, X.M.1    Duenas, E.T.2    Daugherty, A.L.3    Levin, N.4    Cleland, J.L.5
  • 71
    • 0032484233 scopus 로고    scopus 로고
    • Erythropoietin loaded microspheres prepared from biodegradable LPLG-PEO-LPLG triblock copolymers: Protein stabilization and in-vitro release properties
    • Morlock M, Kissel T, Li YX, Koll H, Winter G. Erythropoietin loaded microspheres prepared from biodegradable LPLG-PEO-LPLG triblock copolymers: protein stabilization and in-vitro release properties. J. Control. Release 1998; 56: 105-115.
    • (1998) J. Control. Release , vol.56 , pp. 105-115
    • Morlock, M.1    Kissel, T.2    Li, Y.X.3    Koll, H.4    Winter, G.5
  • 72
    • 0033781504 scopus 로고    scopus 로고
    • The stability of insulin in biodegradable microparticles based on blends of lactide polymers and polyethylene glycol
    • Yeh MK. The stability of insulin in biodegradable microparticles based on blends of lactide polymers and polyethylene glycol. J. Microencapsul. 2000; 17: 743-756.
    • (2000) J. Microencapsul. , vol.17 , pp. 743-756
    • Yeh, M.K.1
  • 73
    • 67650101251 scopus 로고    scopus 로고
    • Preparation and characterization of protein loaded microspheres based on a hydroxylated aliphatic polyester, poly(lactic-co-hydroxymethyl glycolic acid)
    • Ghassemi AH, van Steenbergen MJ, Talsma H, van Nostrum CF, Jiskoot W, Crommelin DJA, Hennink WE. Preparation and characterization of protein loaded microspheres based on a hydroxylated aliphatic polyester, poly(lactic-co-hydroxymethyl glycolic acid). J. Control. Release 2009; 138: 57-63.
    • (2009) J. Control. Release , vol.138 , pp. 57-63
    • Ghassemi, A.H.1    van Steenbergen, M.J.2    Talsma, H.3    van Nostrum, C.F.4    Jiskoot, W.5    Crommelin, D.J.A.6    Hennink, W.E.7
  • 74
    • 0036105205 scopus 로고    scopus 로고
    • Development of oral insulin: Progress and current status
    • Still J. Development of oral insulin: progress and current status. Diabetes Metab. Res. Rev. 2002; 18: S29-S37.
    • (2002) Diabetes Metab. Res. Rev. , vol.18
    • Still, J.1
  • 75
    • 36248965689 scopus 로고    scopus 로고
    • Current challenges in non-invasive insulin delivery systems: A comparative review
    • Khafagy ES, Morishita M, Onuki Y, Takayama K. Current challenges in non-invasive insulin delivery systems: a comparative review. Adv. Drug Deliv. Rev. 2007; 59: 1521-1546.
    • (2007) Adv. Drug Deliv. Rev. , vol.59 , pp. 1521-1546
    • Khafagy, E.S.1    Morishita, M.2    Onuki, Y.3    Takayama, K.4
  • 78
    • 84871615592 scopus 로고    scopus 로고
    • Antacid co-encapsulated polyester nanoparticles for peroral delivery of insulin: Development, pharmacokinetics, biodistribution and pharmacodynamics
    • Sharma G, van der Walle CF, Ravi Kumar MNV. Antacid co-encapsulated polyester nanoparticles for peroral delivery of insulin: Development, pharmacokinetics, biodistribution and pharmacodynamics. Int. J. Pharm. 2013; 440: 99-110.
    • (2013) Int. J. Pharm. , vol.440 , pp. 99-110
    • Sharma, G.1    van der Walle, C.F.2    Ravi Kumar, M.N.V.3


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