HP55-coated capsule containing PLGA/RS nanoparticles for oral delivery of insulin

International Journal of Pharmaceutics

Volumn 425, Issue 1-2, 2012, Pages 1-8

  Wu, Zhi Min ^a   Zhou, Liying ^b   Guo, Xin Dong ^a   Jiang, Wei ^a   Ling, Li ^a   Qian, Yu ^a   Luo, Kathy Qian ^c   Zhang, Li Juan ^a  

^a SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

^b HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

^c Nanyang Technological University   (Singapore)

Author keywords

Enteric capsule; Hypoglycemic effect; Insulin; Nanoparticles; Oral delivery

Indexed keywords

EUDRAGIT RS; HYDROCORTISONE ACETATE PLUS HYDROXYPROPYLMETHYLCELLULOSE PLUS NEOMYCIN PLUS POLYMYXIN B; INSULIN; NANOPARTICLE; POLYGLACTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG CAPSULE; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG RELEASE; EMULSION; EVAPORATION; GLUCOSE BLOOD LEVEL; HYPOGLYCEMIA; INTESTINE; MALE; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PH MEASUREMENT; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RAT; SOLVENT EFFECT; TIME TO MAXIMUM PLASMA CONCENTRATION; ZETA POTENTIAL;

ACRYLIC RESINS; ADMINISTRATION, ORAL; ANIMALS; BLOOD GLUCOSE; CAPSULES; DIABETES MELLITUS, EXPERIMENTAL; DRUG CARRIERS; DRUG STABILITY; FREEZE DRYING; HYDROGEN-ION CONCENTRATION; HYPOGLYCEMIC AGENTS; INSULIN; LACTIC ACID; MALE; METHYLCELLULOSE; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PARTICLE SIZE; POLYGLYCOLIC ACID; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84862777724     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.12.055     Document Type: Article

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