Erythropoietin loaded microspheres prepared from biodegradable LPLG-PEO-LPLG triblock copolymers: Protein stabilization and in-vitro release properties

Journal of Controlled Release

Volumn 56, Issue 1-3, 1998, Pages 105-115

  Morlock, Michael ^a   Kissel, Thomas ^a   Li, You Xin ^a   Koll, Hans ^b   Winter, Gerhard ^b  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

ABA triblock copolymers; Erythropoietin; LPLG PEO LPLG; Microspheres; Protein release; Protein stabilization

Indexed keywords

BOVINE SERUM ALBUMIN; COPOLYMER; DEXTRAN 40; FLUORESCEIN ISOTHIOCYANATE; MACROGOL; MICROSPHERE; POLYGLACTIN; RECOMBINANT ERYTHROPOIETIN;

ARTICLE; BIODEGRADATION; DRUG MANUFACTURE; DRUG RELEASE; DRUG STABILITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL PERMEATION CHROMATOGRAPHY; IN VITRO STUDY; MICROENCAPSULATION; MOLECULAR WEIGHT; PARTICLE SIZE; PRIORITY JOURNAL; TECHNIQUE;

BIOCOMPATIBLE MATERIALS; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DRUG STABILITY; EMULSIONS; ERYTHROPOIETIN, RECOMBINANT; EXCIPIENTS; HUMANS; LACTIC ACID; MICROSPHERES; PHARMACEUTIC AIDS; POLYETHYLENE GLYCOLS; POLYGLYCOLIC ACID; POLYMERS;

EID: 0032484233     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(98)00070-4     Document Type: Article

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