Morphology, drug distribution, and in vitro release profiles of biodegradable polymeric microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method

Biomaterials

Volumn 22, Issue 3, 2001, Pages 231-241

  Yang, Yi Yan ^a   Chung, Tai Shung ^a,b   Ping Ng, Ngee ^b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b Department of Chemical and Environmental Engineering ^*  (Singapore)

Author keywords

Drug distribution; In vitro release profiles; Microsphere morphology; Poly(DL lactic co glycolic acid) 65:35; Polycaprolactone

Indexed keywords

BIODEGRADATION; CONTROLLED DRUG DELIVERY; EVAPORATION; MICROSCOPIC EXAMINATION; MORPHOLOGY; POLYESTERS; PROTEINS; SKIN; SOLVENT EXTRACTION;

DRUG DISTRIBUTION; POLYCAPROLACTONE; POLYMERIC MICROSPHERES;

BIOMATERIALS;

BOVINE SERUM ALBUMIN; EMULSIFYING AGENT; MICROSPHERE; OIL; POLYCAPROLACTONE; POLYESTER; POLYGLACTIN; POLYMER; POLYVINYL ALCOHOL; SOLVENT; WATER;

ARTICLE; BIODEGRADATION; CONCENTRATION (PARAMETERS); CONFOCAL LASER MICROSCOPY; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG RELEASE; EMULSION; EVAPORATION; EXTRACTION; FISH; MOLECULAR WEIGHT; MORPHOLOGY; PARTICLE SIZE; PRECIPITATION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; TROPICS;

BIODEGRADATION, ENVIRONMENTAL; DRUG DELIVERY SYSTEMS; EMULSIONS; KINETICS; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; MOLECULAR WEIGHT; PARTICLE SIZE; SERUM ALBUMIN, BOVINE; SOLVENTS;

BOVINAE; PISCES; POTATO VIRUS A;

EID: 0035255916     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(00)00178-2     Document Type: Article

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