Effect of preparation temperature on the characteristics and release profiles of PLGA microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method

Journal of Controlled Release

Volumn 69, Issue 1, 2000, Pages 81-96

  Yang, Yi Yan ^a   Chia, Hui Hui ^b   Chung, Tai Shung ^a,b  

^a INSTITUTE OF MATERIALS RESEARCH AND ENGINEERING   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

In vitro release profiles; Microspheres; Morphology; Poly(DL lactic co glycolic acid); Preparation temperature; Solvent removal

Indexed keywords

BOVINE SERUM ALBUMIN; MICROSPHERE; POLYGLACTIN;

ARTICLE; ATOMIC FORCE MICROSCOPY; DENSITY; DRUG RELEASE; ENCAPSULATION; EVAPORATION; PARTICLE SIZE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SOLUBILITY; TEMPERATURE;

ALGORITHMS; CHEMISTRY, PHYSICAL; DRUG CARRIERS; DRUG COMPOUNDING; EXCIPIENTS; LACTIC ACID; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; PARTICLE SIZE; POLYGLYCOLIC ACID; POLYMERS; PROTEINS; SERUM ALBUMIN, BOVINE; SOLVENTS; TEMPERATURE;

EID: 0034601882     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(00)00291-1     Document Type: Article

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