-
1
-
-
79952179441
-
Immune pathomechanism of drug hypersensitivity reactions
-
Pichler W.J., Naisbitt D.J., Park B.K. Immune pathomechanism of drug hypersensitivity reactions. JAllergy Clin Immunol 2011, 127(Suppl 3):S74-S81.
-
(2011)
JAllergy Clin Immunol
, vol.127
, Issue.SUPPL 3
-
-
Pichler, W.J.1
Naisbitt, D.J.2
Park, B.K.3
-
2
-
-
0003702992
-
-
Blackwell, Oxford (United Kingdom), P.G. Gell, R.R. Coombs (Eds.)
-
Clinical aspects of immunology 1963, Blackwell, Oxford (United Kingdom). P.G. Gell, R.R. Coombs (Eds.).
-
(1963)
Clinical aspects of immunology
-
-
-
3
-
-
0142087834
-
Delayed drug hypersensitivity reactions
-
Pichler W.J. Delayed drug hypersensitivity reactions. Ann Intern Med 2003, 139(8):683-693.
-
(2003)
Ann Intern Med
, vol.139
, Issue.8
, pp. 683-693
-
-
Pichler, W.J.1
-
4
-
-
84873304792
-
Human leukocyte antigen (HLA)-B*57:01-restricted activation of drug-specific T cells provides the immunological basis for flucloxacillin-induced liver injury
-
Monshi M.M., Faulkner L., Gibson A., et al. Human leukocyte antigen (HLA)-B*57:01-restricted activation of drug-specific T cells provides the immunological B*57(2):727-739.
-
(2013)
Hepatology
, vol.57
, Issue.2
, pp. 727-739
-
-
Monshi, M.M.1
Faulkner, L.2
Gibson, A.3
-
5
-
-
33749242789
-
Involvement of drug-specific T cells in acute drug-induced interstitial nephritis
-
Spanou Z., Keller M., Britschgi M., et al. Involvement of drug-specific T cells in acute drug-induced interstitial nephritis. JAm Soc Nephrol 2006, 17(10):2919-2927.
-
(2006)
JAm Soc Nephrol
, vol.17
, Issue.10
, pp. 2919-2927
-
-
Spanou, Z.1
Keller, M.2
Britschgi, M.3
-
6
-
-
84880763009
-
Idiosyncratic adverse drug reactions: current concepts
-
Uetrecht J., Naisbitt D.J. Idiosyncratic adverse drug reactions: current concepts. Pharmacol Rev 2013, 65(2):779-808.
-
(2013)
Pharmacol Rev
, vol.65
, Issue.2
, pp. 779-808
-
-
Uetrecht, J.1
Naisbitt, D.J.2
-
7
-
-
84875277121
-
Human leukocyte antigen-associated drug hypersensitivity
-
Illing P.T., Vivian J.P., Purcell A.W., et al. Human leukocyte antigen-associated drug hypersensitivity. Curr Opin Immunol 2013, 25(1):81-89.
-
(2013)
Curr Opin Immunol
, vol.25
, Issue.1
, pp. 81-89
-
-
Illing, P.T.1
Vivian, J.P.2
Purcell, A.W.3
-
8
-
-
84887317009
-
Consequences of drug binding to immune receptors: immune stimulation following pharmacological interaction with immune receptors (T-cell receptor for antigen or human leukocyte antigen) with altered peptide-human leukocyte antigen or peptide
-
Pichler W.J. Consequences of drug binding to immune receptors: immune stimulation following pharmacological interaction with immune receptors (T-cell receptor for antigen or human leukocyte antigen) with altered peptide-human leukocyte antigen or peptide. Dermatologica Sinica 2013, 31(4):181-190.
-
(2013)
Dermatologica Sinica
, vol.31
, Issue.4
, pp. 181-190
-
-
Pichler, W.J.1
-
9
-
-
0029595333
-
Structure activity relationships in skin sensitization using the murine local lymph node assay
-
Ashby J., Basketter D.A., Paton D., et al. Structure activity relationships in skin sensitization using the murine local lymph node assay. Toxicology 1995, 103(3):177-194.
-
(1995)
Toxicology
, vol.103
, Issue.3
, pp. 177-194
-
-
Ashby, J.1
Basketter, D.A.2
Paton, D.3
-
10
-
-
84973718396
-
Studies on the sensitization of animals with simple chemical compounds
-
Landsteiner K., Jacobs J. Studies on the sensitization of animals with simple chemical compounds. JExp Med 1935, 61:643-656.
-
(1935)
JExp Med
, vol.61
, pp. 643-656
-
-
Landsteiner, K.1
Jacobs, J.2
-
11
-
-
78651328041
-
T-cell recognition of chemicals, protein allergens and drugs: towards the development of invitro assays
-
Martin S.F., Esser P.R., Schmucker S., et al. T-cell recognition of chemicals, protein allergens and drugs: towards the development of invitro assays. Cell Mol Life Sci 2010, 67(24):4171-4184.
-
(2010)
Cell Mol Life Sci
, vol.67
, Issue.24
, pp. 4171-4184
-
-
Martin, S.F.1
Esser, P.R.2
Schmucker, S.3
-
12
-
-
71049153638
-
Investigation of peptide reactivity of pro-hapten skin sensitizers using a peroxidase-peroxide oxidation system
-
Gerberick G.F., Troutman J.A., Foertsch L.M., et al. Investigation of peptide reactivity of pro-hapten skin sensitizers using a peroxidase-peroxide oxidation system. Toxicol Sci 2009, 112(1):164-174.
-
(2009)
Toxicol Sci
, vol.112
, Issue.1
, pp. 164-174
-
-
Gerberick, G.F.1
Troutman, J.A.2
Foertsch, L.M.3
-
13
-
-
45549085219
-
Chemical reactivity measurement and the predictive identification of skin sensitisers. The report and recommendations of ECVAM Workshop 64
-
Gerberick F., Aleksic M., Basketter D., et al. Chemical reactivity measurement and the predictive identification of skin sensitisers. The report and recommendations of ECVAM Workshop 64. Altern Lab Anim 2008, 36(2):215-242.
-
(2008)
Altern Lab Anim
, vol.36
, Issue.2
, pp. 215-242
-
-
Gerberick, F.1
Aleksic, M.2
Basketter, D.3
-
14
-
-
84871646577
-
Overview of penicillin allergy
-
Chang C., Mahmood M.M., Teuber S.S., et al. Overview of penicillin allergy. Clin Rev Allergy Immunol 2012, 43(1-2):84-97.
-
(2012)
Clin Rev Allergy Immunol
, vol.43
, Issue.1-2
, pp. 84-97
-
-
Chang, C.1
Mahmood, M.M.2
Teuber, S.S.3
-
15
-
-
0014422093
-
Hypersensitivity to the penicillins
-
Pullen H., Wright N., Murdock J.M. Hypersensitivity to the penicillins. Lancet 1968, 1(7551):1090.
-
(1968)
Lancet
, vol.1
, Issue.7551
, pp. 1090
-
-
Pullen, H.1
Wright, N.2
Murdock, J.M.3
-
16
-
-
0000973752
-
Penicillin allergy: the formation of the penicilloyl determinant
-
Batchelor F.R., Dewdney J.M., Gazzard D. Penicillin allergy: the formation of the penicilloyl determinant. Nature 1965, 206:362-364.
-
(1965)
Nature
, vol.206
, pp. 362-364
-
-
Batchelor, F.R.1
Dewdney, J.M.2
Gazzard, D.3
-
17
-
-
0003190104
-
Studies on the mechanism of the formation of the penicillin antigen. III. The N-(D-alpha-benzylpenicilloyl) group as an antigenic determinant responsible for hypersensitivity to penicillin G
-
Levine B.B., Ovary Z. Studies on the mechanism of the formation of the penicillin antigen. III. The N-(D-alpha-benzylpenicilloyl) group as an antigenic determinant responsible for hypersensitivity to penicillin G. JExp Med 1961, 114:875-904.
-
(1961)
JExp Med
, vol.114
, pp. 875-904
-
-
Levine, B.B.1
Ovary, Z.2
-
18
-
-
2142733653
-
Studies on the mechanism of the formation of the penicillin antigen. I.Delayed allergic cross-reactions among penicillin G and its degradation products
-
Levine B.B. Studies on the mechanism of the formation of the penicillin antigen. I.Delayed allergic cross-reactions among penicillin G and its degradation products. JExp Med 1960, 112:1131-1156.
-
(1960)
JExp Med
, vol.112
, pp. 1131-1156
-
-
Levine, B.B.1
-
19
-
-
84861535807
-
Characterization of the antigen specificity of T-cell clones from piperacillin-hypersensitive patients with cystic fibrosis
-
El-Ghaiesh S., Monshi M.M., Whitaker P., et al. Characterization of the antigen specificity of T-cell clones from piperacillin-hypersensitive patients with cystic fibrosis. JPharmacol Exp Ther 2012, 341(3):597-610.
-
(2012)
JPharmacol Exp Ther
, vol.341
, Issue.3
, pp. 597-610
-
-
El-Ghaiesh, S.1
Monshi, M.M.2
Whitaker, P.3
-
20
-
-
79960427633
-
Mass spectrometric characterization of circulating and functional antigens derived from piperacillin in patients with cystic fibrosis
-
Whitaker P., Meng X., Lavergne S.N., et al. Mass spectrometric characterization of circulating and functional antigens derived from piperacillin in patients with cystic fibrosis. JImmunol 2011, 187(1):200-211.
-
(2011)
JImmunol
, vol.187
, Issue.1
, pp. 200-211
-
-
Whitaker, P.1
Meng, X.2
Lavergne, S.N.3
-
21
-
-
80052152347
-
Direct evidence for the formation of diastereoisomeric benzylpenicilloyl haptens from benzylpenicillin and benzylpenicillenic acid in patients
-
Meng X., Jenkins R.E., Berry N., et al. Direct evidence for the formation of diastereoisomeric benzylpenicilloyl haptens from benzylpenicillin and benzylpenicillenic acid in patients. JPharmacol Exp Ther 2011, 338:841-849.
-
(2011)
JPharmacol Exp Ther
, vol.338
, pp. 841-849
-
-
Meng, X.1
Jenkins, R.E.2
Berry, N.3
-
22
-
-
75149137515
-
Metabolic and chemical origins of cross-reactive immunological reactions to arylamine benzenesulfonamides: T-cell responses to hydroxylamine and nitroso derivatives
-
Castrejon J.L., Lavergne S.N., El-Sheikh A., et al. Metabolic and chemical origins of cross-reactive immunological reactions to arylamine benzenesulfonamides: T-cell responses to hydroxylamine and nitroso derivatives. Chem Res Toxicol 2010, 23(1):184-192.
-
(2010)
Chem Res Toxicol
, vol.23
, Issue.1
, pp. 184-192
-
-
Castrejon, J.L.1
Lavergne, S.N.2
El-Sheikh, A.3
-
23
-
-
67649992761
-
Multiple adduction reactions of nitroso sulfamethoxazole with cysteinyl residues of peptides and proteins: implications for hapten formation
-
Callan H.E., Jenkins R.E., Maggs J.L., et al. Multiple adduction reactions of nitroso sulfamethoxazole with cysteinyl residues of peptides and proteins: implications for hapten formation. Chem Res Toxicol 2009, 22(5):937-948.
-
(2009)
Chem Res Toxicol
, vol.22
, Issue.5
, pp. 937-948
-
-
Callan, H.E.1
Jenkins, R.E.2
Maggs, J.L.3
-
24
-
-
34247552226
-
Sulfamethoxazole and its metabolite nitroso sulfamethoxazole stimulate dendritic cell costimulatory signaling
-
Sanderson J.P., Naisbitt D.J., Farrell J., et al. Sulfamethoxazole and its metabolite nitroso sulfamethoxazole stimulate dendritic cell costimulatory signaling. JImmunol 2007, 178(9):5533-5542.
-
(2007)
JImmunol
, vol.178
, Issue.9
, pp. 5533-5542
-
-
Sanderson, J.P.1
Naisbitt, D.J.2
Farrell, J.3
-
25
-
-
0036765861
-
Covalent binding of the nitroso metabolite of sulfamethoxazole leads to toxicity and major histocompatibility complex-restricted antigen presentation
-
Naisbitt D.J., Farrell J., Gordon S.F., et al. Covalent binding of the nitroso metabolite of sulfamethoxazole leads to toxicity and major histocompatibility complex-restricted antigen presentation. Mol Pharmacol 2002, 62(3):628-637.
-
(2002)
Mol Pharmacol
, vol.62
, Issue.3
, pp. 628-637
-
-
Naisbitt, D.J.1
Farrell, J.2
Gordon, S.F.3
-
26
-
-
67349218444
-
Role of protein haptenation in triggering maturation events in the dendritic cell surrogate cell line THP-1
-
Megherbi R., Kiorpelidou E., Foster B., et al. Role of protein haptenation in triggering maturation events in the dendritic cell surrogate cell line THP-1. Toxicol Appl Pharmacol 2009, 238(2):120-132.
-
(2009)
Toxicol Appl Pharmacol
, vol.238
, Issue.2
, pp. 120-132
-
-
Megherbi, R.1
Kiorpelidou, E.2
Foster, B.3
-
27
-
-
73349087840
-
The cutaneous biochemical redox barrier: a component of the innate immune defenses against sensitization by highly reactive environmental xenobiotics
-
Pickard C., Louafi F., McGuire C., et al. The cutaneous B*576-7584.
-
(2009)
JImmunol
, vol.183
, Issue.11
, pp. 7576-7584
-
-
Pickard, C.1
Louafi, F.2
McGuire, C.3
-
28
-
-
33847046015
-
Investigation of mechanisms underlying the T-cell response to the hapten 2,4-dinitrochlorobenzene
-
Pickard C., Smith A.M., Cooper H., et al. Investigation of mechanisms underlying the T-cell response to the hapten 2,4-dinitrochlorobenzene. JInvest Dermatol 2007, 127(3):630-637.
-
(2007)
JInvest Dermatol
, vol.127
, Issue.3
, pp. 630-637
-
-
Pickard, C.1
Smith, A.M.2
Cooper, H.3
-
29
-
-
70350113458
-
Characterisation of flucloxacillin and 5-hydroxymethyl flucloxacillin haptenated HSA invitro and invivo
-
Jenkins R.E., Meng X., Elliott V.L., et al. Characterisation of flucloxacillin and 5-hydroxymethyl flucloxacillin haptenated HSA invitro and invivo. Proteomics Clin Appl 2009, 3(6):720-729.
-
(2009)
Proteomics Clin Appl
, vol.3
, Issue.6
, pp. 720-729
-
-
Jenkins, R.E.1
Meng, X.2
Elliott, V.L.3
-
30
-
-
0027258555
-
Selective generation of CD8+ T-cell clones from the peripheral blood of patients with cutaneous reactions to beta-lactam antibiotics
-
Hertl M., Geisel J., Boecker C., et al. Selective generation of CD8+ T-cell clones from the peripheral blood of patients with cutaneous reactions to beta-lactam antibiotics. Br J Dermatol 1993, 128:619-626.
-
(1993)
Br J Dermatol
, vol.128
, pp. 619-626
-
-
Hertl, M.1
Geisel, J.2
Boecker, C.3
-
31
-
-
0035999867
-
Determination of interleukin-5 secretion from drug-specific activated exvivo peripheral blood mononuclear cells as a test system for the invitro detection of drug sensitization
-
Sachs B., Erdmann S., Malte Baron J., et al. Determination of interleukin-5 secretion from drug-specific activated exvivo peripheral blood mononuclear cells as a test system for the invitro detection of drug sensitization. Clin Exp Allergy 2002, 32(5):736-744.
-
(2002)
Clin Exp Allergy
, vol.32
, Issue.5
, pp. 736-744
-
-
Sachs, B.1
Erdmann, S.2
Malte Baron, J.3
-
32
-
-
62449098612
-
Detection and quantification of drug-specific T cells in penicillin allergy
-
Rozieres A., Hennino A., Rodet K., et al. Detection and quantification of drug-specific T cells in penicillin allergy. Allergy 2009, 64(4):534-542.
-
(2009)
Allergy
, vol.64
, Issue.4
, pp. 534-542
-
-
Rozieres, A.1
Hennino, A.2
Rodet, K.3
-
33
-
-
31944435105
-
Long-lasting reactivity and high frequency of drug-specific T cells after severe systemic drug hypersensitivity reactions
-
Beeler A., Engler O., Gerber B.O., et al. Long-lasting reactivity and high frequency of drug-specific T cells after severe systemic drug hypersensitivity reactions. JAllergy Clin Immunol 2006, 117(2):455-462.
-
(2006)
JAllergy Clin Immunol
, vol.117
, Issue.2
, pp. 455-462
-
-
Beeler, A.1
Engler, O.2
Gerber, B.O.3
-
34
-
-
0033565618
-
Highly Th2-skewed cytokine profile of beta-lactam-specific T cells from nonatopic subjects with adverse drug reactions
-
Brugnolo F., Annunziato F., Sampognaro S., et al. Highly Th2-skewed cytokine profile of beta-lactam-specific T cells from nonatopic subjects with adverse drug reactions. JImmunol 1999, 163(2):1053-1059.
-
(1999)
JImmunol
, vol.163
, Issue.2
, pp. 1053-1059
-
-
Brugnolo, F.1
Annunziato, F.2
Sampognaro, S.3
-
35
-
-
0030210948
-
Cross-reactivity of T cell lines and clones to beta-lactam antibiotics
-
Mauri-Hellweg D., Zanni M., Frei E., et al. Cross-reactivity of T cell lines and clones to B*57(3):1071-1079.
-
(1996)
JImmunol
, vol.157
, Issue.3
, pp. 1071-1079
-
-
Mauri-Hellweg, D.1
Zanni, M.2
Frei, E.3
-
36
-
-
0029068773
-
Heterogeneous T cell responses to beta-lactam-modified self-structures are observed in penicillin-allergic individuals
-
Brander C., Mauri-Hellweg D., Bettens F., et al. Heterogeneous T cell responses to beta-lactam-modified self-structures are observed in penicillin-allergic individuals. JImmunol 1995, 155(5):2670-2678.
-
(1995)
JImmunol
, vol.155
, Issue.5
, pp. 2670-2678
-
-
Brander, C.1
Mauri-Hellweg, D.2
Bettens, F.3
-
37
-
-
84880265732
-
Identification and frequency of circulating CD4(+) T lymphocytes specific to benzylpenicillin in healthy donors
-
Nhim C., Delluc S., Halgand F., et al. Identification and frequency of circulating CD4(+) T lymphocytes specific to benzylpenicillin in healthy donors. Allergy 2013, 68(7):899-905.
-
(2013)
Allergy
, vol.68
, Issue.7
, pp. 899-905
-
-
Nhim, C.1
Delluc, S.2
Halgand, F.3
-
38
-
-
0030029973
-
Tcell recognition of penicillin G: structural features determining antigenic specificity
-
Padovan E., Mauri-Hellweg D., Pichler W.J., et al. Tcell recognition of penicillin G: structural features determining antigenic specificity. Eur J Immunol 1996, 26:42-48.
-
(1996)
Eur J Immunol
, vol.26
, pp. 42-48
-
-
Padovan, E.1
Mauri-Hellweg, D.2
Pichler, W.J.3
-
39
-
-
0036840668
-
Haptenation of sulfonamide reactive metabolites to cellular proteins
-
Manchanda T., Hess D., Dale L., et al. Haptenation of sulfonamide reactive metabolites to cellular proteins. Mol Pharmacol 2002, 62(5):1011-1026.
-
(2002)
Mol Pharmacol
, vol.62
, Issue.5
, pp. 1011-1026
-
-
Manchanda, T.1
Hess, D.2
Dale, L.3
-
40
-
-
0034980953
-
Antigenicity and immunogenicity of sulphamethoxazole: demonstration of metabolism-dependent haptenation and T-cell proliferation invivo
-
Naisbitt D.J., Gordon S.F., Pirmohamed M., et al. Antigenicity and immunogenicity of sulphamethoxazole: demonstration of metabolism-dependent haptenation and T-cell proliferation invivo. Br J Pharmacol 2001, 133(2):295-305.
-
(2001)
Br J Pharmacol
, vol.133
, Issue.2
, pp. 295-305
-
-
Naisbitt, D.J.1
Gordon, S.F.2
Pirmohamed, M.3
-
41
-
-
0038340979
-
Characterization of sulfamethoxazole and sulfamethoxazole metabolite-specific T-cell responses in animals and humans
-
Farrell J., Naisbitt D.J., Drummond N.S., et al. Characterization of sulfamethoxazole and sulfamethoxazole metabolite-specific T-cell responses in animals and humans. JPharmacol Exp Ther 2003, 306(1):229-237.
-
(2003)
JPharmacol Exp Ther
, vol.306
, Issue.1
, pp. 229-237
-
-
Farrell, J.1
Naisbitt, D.J.2
Drummond, N.S.3
-
42
-
-
84860188978
-
The development of invitro culture methods to characterize primary T cell responses to drugs
-
Faulkner L., Martinsson K., Castelazo A.S., et al. The development of invitro culture methods to characterize primary T cell responses to drugs. Toxicol Sci 2012, 127:150-158.
-
(2012)
Toxicol Sci
, vol.127
, pp. 150-158
-
-
Faulkner, L.1
Martinsson, K.2
Castelazo, A.S.3
-
43
-
-
1542285424
-
Achemically inert drug can stimulate Tcells invitro by their T cell receptor in non-sensitised individuals
-
Engler O.B., Strasser I., Naisbitt D.J., et al. Achemically inert drug can stimulate Tcells invitro by their T cell receptor in non-sensitised individuals. Toxicology 2004, 197(1):47-56.
-
(2004)
Toxicology
, vol.197
, Issue.1
, pp. 47-56
-
-
Engler, O.B.1
Strasser, I.2
Naisbitt, D.J.3
-
44
-
-
75849160138
-
Stimulation of human T cells with sulfonamides and sulfonamide metabolites
-
Castrejon J.L., Berry N., El-Ghaiesh S., et al. Stimulation of human T cells with sulfonamides and sulfonamide metabolites. JAllergy Clin Immunol 2010, 125(2):411-418.e4.
-
(2010)
JAllergy Clin Immunol
, vol.125
, Issue.2
-
-
Castrejon, J.L.1
Berry, N.2
El-Ghaiesh, S.3
-
45
-
-
0034660184
-
Recognition of sulfamethoxazole and its reactive metabolites by drug-specific CD4+ T cells from allergic individuals
-
Schnyder B., Burkhart C., Schnyder-Frutig K., et al. Recognition of sulfamethoxazole and its reactive metabolites by drug-specific CD4+ T cells from allergic individuals. JImmunol 2000, 164(12):6647-6654.
-
(2000)
JImmunol
, vol.164
, Issue.12
, pp. 6647-6654
-
-
Schnyder, B.1
Burkhart, C.2
Schnyder-Frutig, K.3
-
46
-
-
7944234979
-
Toxic epidermal necrolysis: effector cells are drug-specific cytotoxic T cells
-
Nassif A., Bensussan A., Boumsell L., et al. Toxic epidermal necrolysis: effector cells are drug-specific cytotoxic T cells. JAllergy Clin Immunol 2004, 114(5):1209-1215.
-
(2004)
JAllergy Clin Immunol
, vol.114
, Issue.5
, pp. 1209-1215
-
-
Nassif, A.1
Bensussan, A.2
Boumsell, L.3
-
47
-
-
79952117348
-
Drug antigenicity, immunogenicity, and costimulatory signaling: evidence for formation of a functional antigen through immune cell metabolism
-
Elsheikh A., Lavergne S.N., Castrejon J.L., et al. Drug antigenicity, immunogenicity, and costimulatory signaling: evidence for formation of a functional antigen through immune cell metabolism. JImmunol 2010, 185(11):6448-6460.
-
(2010)
JImmunol
, vol.185
, Issue.11
, pp. 6448-6460
-
-
Elsheikh, A.1
Lavergne, S.N.2
Castrejon, J.L.3
-
48
-
-
79957834898
-
Enhanced antigenicity leads to altered immunogenicity in sulfamethoxazole-hypersensitive patients with cystic fibrosis
-
Elsheikh A., Castrejon L., Lavergne S.N., et al. Enhanced antigenicity leads to altered immunogenicity in sulfamethoxazole-hypersensitive patients with cystic fibrosis. JAllergy Clin Immunol 2011, 127(6):1543-1551.e3.
-
(2011)
JAllergy Clin Immunol
, vol.127
, Issue.6
-
-
Elsheikh, A.1
Castrejon, L.2
Lavergne, S.N.3
-
49
-
-
77953760907
-
Drug metabolite-specific lymphocyte responses in sulfamethoxazole allergic patients with cystic fibrosis
-
Lavergne S.N., Whitaker P., Peckham D., et al. Drug metabolite-specific lymphocyte responses in sulfamethoxazole allergic patients with cystic fibrosis. Chem Res Toxicol 2010, 23(6):1009-1011.
-
(2010)
Chem Res Toxicol
, vol.23
, Issue.6
, pp. 1009-1011
-
-
Lavergne, S.N.1
Whitaker, P.2
Peckham, D.3
-
50
-
-
84867557298
-
Human leukocyte antigens (HLA) associated drug hypersensitivity: consequences of drug binding to HLA
-
Yun J., Adam J., Yerly D., et al. Human leukocyte antigens (HLA) associated drug hypersensitivity: consequences of drug binding to HLA. Allergy 2012, 67:1338-1346.
-
(2012)
Allergy
, vol.67
, pp. 1338-1346
-
-
Yun, J.1
Adam, J.2
Yerly, D.3
-
51
-
-
0029060517
-
Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin, and carbamazepine
-
Mauri-Hellweg D., Bettens F., Mauri D., et al. Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin, and carbamazepine. JImmunol 1995, 155(1):462-472.
-
(1995)
JImmunol
, vol.155
, Issue.1
, pp. 462-472
-
-
Mauri-Hellweg, D.1
Bettens, F.2
Mauri, D.3
-
52
-
-
0035112838
-
Influence of reduced glutathione on the proliferative response of sulfamethoxazole-specific and sulfamethoxazole-metabolite-specific human CD4+ T-cells
-
Burkhart C., von Greyerz S., Depta J.P., et al. Influence of reduced glutathione on the proliferative response of sulfamethoxazole-specific and sulfamethoxazole-metabolite-specific human CD4+ T-cells. Br J Pharmacol 2001, 132(3):623-630.
-
(2001)
Br J Pharmacol
, vol.132
, Issue.3
, pp. 623-630
-
-
Burkhart, C.1
von Greyerz, S.2
Depta, J.P.3
-
53
-
-
0032532378
-
HLA-restricted, processing- and metabolism-independent pathway of drug recognition by human alpha beta Tlymphocytes
-
Zanni M.P., von Greyerz S., Schnyder B., et al. HLA-restricted, processing- and metabolism-independent pathway of drug recognition by human alpha beta Tlymphocytes. JClin Invest 1998, 102(8):1591-1598.
-
(1998)
JClin Invest
, vol.102
, Issue.8
, pp. 1591-1598
-
-
Zanni, M.P.1
von Greyerz, S.2
Schnyder, B.3
-
54
-
-
0030822702
-
Direct, MHC-dependent presentation of the drug sulfamethoxazole to human alphabeta T cell clones
-
Schnyder B., Mauri-Hellweg D., Zanni M., et al. Direct, MHC-dependent presentation of the drug sulfamethoxazole to human alphabeta T cell clones. JClin Invest 1997, 100(1):136-141.
-
(1997)
JClin Invest
, vol.100
, Issue.1
, pp. 136-141
-
-
Schnyder, B.1
Mauri-Hellweg, D.2
Zanni, M.3
-
55
-
-
84877792047
-
HLA haplotype determines hapten or p-i T cell reactivity to flucloxacillin
-
Wuillemin N., Adam J., Fontana S., et al. HLA haplotype determines hapten or p-i T cell reactivity to flucloxacillin. JImmunol 2013, 190(10):4956-4964.
-
(2013)
JImmunol
, vol.190
, Issue.10
, pp. 4956-4964
-
-
Wuillemin, N.1
Adam, J.2
Fontana, S.3
-
57
-
-
38949196447
-
HLA-B*5701 screening for hypersensitivity to abacavir
-
Mallal S., Phillips E., Carosi G., et al. HLA-B*5701 screening for hypersensitivity to aB*579.
-
(2008)
NEngl J Med
, vol.358
, Issue.6
, pp. 568-579
-
-
Mallal, S.1
Phillips, E.2
Carosi, G.3
-
58
-
-
84862979660
-
Immune self-reactivity triggered by drug-modified HLA-peptide repertoire
-
Illing P.T., Vivian J.P., Dudek N.L., et al. Immune self-reactivity triggered by drug-modified HLA-peptide repertoire. Nature 2012, 486(7404):554-558.
-
(2012)
Nature
, vol.486
, Issue.7404
, pp. 554-558
-
-
Illing, P.T.1
Vivian, J.P.2
Dudek, N.L.3
-
59
-
-
84862532297
-
Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire
-
Ostrov D.A., Grant B.J., Pompeu Y.A., et al. Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire. Proc Natl Acad Sci USA 2012, 109(25):9959-9964.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.25
, pp. 9959-9964
-
-
Ostrov, D.A.1
Grant, B.J.2
Pompeu, Y.A.3
-
60
-
-
84863721147
-
AB*57: 01: an autoimmune model for HLA-associated drug hypersensitivity
-
Norcross M.A., Luo S., Lu L., et al. AB*57: 01: an autoimmune model for HLA-associated drug hypersensitivity. AIDS 2012, 26(11):F21-F29.
-
(2012)
AIDS
, vol.26
, Issue.11
-
-
Norcross, M.A.1
Luo, S.2
Lu, L.3
-
61
-
-
44649104544
-
Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity
-
Chessman D., Kostenko L., Lethborg T., et al. Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity. Immunity 2008, 28(6):822-832.
-
(2008)
Immunity
, vol.28
, Issue.6
, pp. 822-832
-
-
Chessman, D.1
Kostenko, L.2
Lethborg, T.3
-
62
-
-
0031050054
-
The lymphocyte transformation test for the diagnosis of drug allergy: sensitivity and specificity
-
Nyfeler B., Pichler W.J. The lymphocyte transformation test for the diagnosis of drug allergy: sensitivity and specificity. Clin Exp Allergy 1997, 27:175-181.
-
(1997)
Clin Exp Allergy
, vol.27
, pp. 175-181
-
-
Nyfeler, B.1
Pichler, W.J.2
-
63
-
-
3442876477
-
The lymphocyte transformation test in the diagnosis of drug hypersensitivity
-
Pichler W.J., Tilch J. The lymphocyte transformation test in the diagnosis of drug hypersensitivity. Allergy 2004, 59(8):809-820.
-
(2004)
Allergy
, vol.59
, Issue.8
, pp. 809-820
-
-
Pichler, W.J.1
Tilch, J.2
-
64
-
-
34047103842
-
Generation and characterization of antigen-specific CD4+, CD8+, and CD4+CD8+ T-cell clones from patients with carbamazepine hypersensitivity
-
Wu Y., Farrell J., Pirmohamed M., et al. Generation and characterization of antigen-specific CD4+, CD8+, and CD4+CD8+ T-cell clones from patients with carbamazepine hypersensitivity. JAllergy Clin Immunol 2007, 119(4):973-981.
-
(2007)
JAllergy Clin Immunol
, vol.119
, Issue.4
, pp. 973-981
-
-
Wu, Y.1
Farrell, J.2
Pirmohamed, M.3
-
65
-
-
33745672091
-
Activation of T cells by carbamazepine and carbamazepine metabolites
-
Wu Y., Sanderson J.P., Farrell J., et al. Activation of T cells by carbamazepine and carbamazepine metabolites. JAllergy Clin Immunol 2006, 118(1):233-241.
-
(2006)
JAllergy Clin Immunol
, vol.118
, Issue.1
, pp. 233-241
-
-
Wu, Y.1
Sanderson, J.P.2
Farrell, J.3
-
66
-
-
0344951264
-
Hypersensitivity reactions to carbamazepine: characterization of the specificity, phenotype, and cytokine profile of drug-specific T cell clones
-
Naisbitt D.J., Britschgi M., Wong G., et al. Hypersensitivity reactions to carbamazepine: characterization of the specificity, phenotype, and cytokine profile of drug-specific T cell clones. Mol Pharmacol 2003, 63(3):732-741.
-
(2003)
Mol Pharmacol
, vol.63
, Issue.3
, pp. 732-741
-
-
Naisbitt, D.J.1
Britschgi, M.2
Wong, G.3
-
67
-
-
0038797941
-
Characterization of drug-specific T cells in lamotrigine hypersensitivity
-
Naisbitt D.J., Farrell J., Wong G., et al. Characterization of drug-specific T cells in lamotrigine hypersensitivity. JAllergy Clin Immunol 2003, 111(6):1393-1403.
-
(2003)
JAllergy Clin Immunol
, vol.111
, Issue.6
, pp. 1393-1403
-
-
Naisbitt, D.J.1
Farrell, J.2
Wong, G.3
-
68
-
-
84882775239
-
Invitro drug causality assessment in Stevens-Johnson syndrome - alternatives for lymphocyte transformation test
-
Porebski G., Pecaric-Petkovic T., Groux-Keller M., et al. Invitro drug causality assessment in Stevens-Johnson syndrome - alternatives for lymphocyte transformation test. Clin Exp Allergy 2013, 43(9):1027-1037.
-
(2013)
Clin Exp Allergy
, vol.43
, Issue.9
, pp. 1027-1037
-
-
Porebski, G.1
Pecaric-Petkovic, T.2
Groux-Keller, M.3
-
70
-
-
0036230022
-
Drug specific cytotoxic T-cells in the skin lesions of a patient with toxic epidermal necrolysis
-
Nassif A., Bensussan A., Dorothee G., et al. Drug specific cytotoxic T-cells in the skin lesions of a patient with toxic epidermal necrolysis. JInvest Dermatol 2002, 118(4):728-733.
-
(2002)
JInvest Dermatol
, vol.118
, Issue.4
, pp. 728-733
-
-
Nassif, A.1
Bensussan, A.2
Dorothee, G.3
-
71
-
-
84882280172
-
Invitro diagnostic assays are effective during the acute phase of delayed-type drug hypersensitivity reactions
-
Polak M.E., Belgi G., McGuire C., et al. Invitro diagnostic assays are effective during the acute phase of delayed-type drug hypersensitivity reactions. Br J Dermatol 2013, 168(3):539-549.
-
(2013)
Br J Dermatol
, vol.168
, Issue.3
, pp. 539-549
-
-
Polak, M.E.1
Belgi, G.2
McGuire, C.3
-
72
-
-
37749048434
-
CD69 upregulation on T cells as an invitro marker for delayed-type drug hypersensitivity
-
Beeler A., Zaccaria L., Kawabata T., et al. CD69 upregulation on T cells as an invitro marker for delayed-type drug hypersensitivity. Allergy 2008, 63(2):181-188.
-
(2008)
Allergy
, vol.63
, Issue.2
, pp. 181-188
-
-
Beeler, A.1
Zaccaria, L.2
Kawabata, T.3
-
73
-
-
76249130394
-
Invitro detection of cytotoxic T and NK cells in peripheral blood of patients with various drug-induced skin diseases
-
Zawodniak A., Lochmatter P., Yerly D., et al. Invitro detection of cytotoxic T and NK cells in peripheral blood of patients with various drug-induced skin diseases. Allergy 2010, 65(3):376-384.
-
(2010)
Allergy
, vol.65
, Issue.3
, pp. 376-384
-
-
Zawodniak, A.1
Lochmatter, P.2
Yerly, D.3
-
74
-
-
84866490968
-
Recovered patients with Stevens-Johson syndrome and toxic epidermal necrolysis maintain long-lived IFN-gamma and sFasL memory response
-
Fu M., Gao Y., Pan Y., et al. Recovered patients with Stevens-Johson syndrome and toxic epidermal necrolysis maintain long-lived IFN-gamma and sFasL memory response. PLoS One 2012, 7(9):e45516.
-
(2012)
PLoS One
, vol.7
, Issue.9
-
-
Fu, M.1
Gao, Y.2
Pan, Y.3
-
75
-
-
84877983147
-
T-cells from HLA-B*57:01+ human subjects are activated with abacavir through two independent pathways and induce cell death by multiple mechanisms
-
B*57:01+ human subjects are activated with abacavir through two independent pathways and induce cell death by multiple mechanisms. Chem Res Toxicol 2013, 26(5):759-766.
-
(2013)
Chem Res Toxicol
, vol.26
, Issue.5
, pp. 759-766
-
-
Bell, C.C.1
Faulkner, L.2
Martinsson, K.3
-
76
-
-
84875377558
-
Human T cell priming assay (hTCPA) for the identification of contact allergens based on naive T cells and DC-IFN-gamma and TNF-alpha readout
-
Richter A., Schmucker S.S., Esser P.R., et al. Human T cell priming assay (hTCPA) for the identification of contact allergens based on naive T cells and DC-IFN-gamma and TNF-alpha readout. Toxicol InVitro 2013, 27(3):1180-1185.
-
(2013)
Toxicol InVitro
, vol.27
, Issue.3
, pp. 1180-1185
-
-
Richter, A.1
Schmucker, S.S.2
Esser, P.R.3
-
77
-
-
0035051090
-
Pathogenesis of drug-induced exanthema
-
Yawalkar N., Pichler W.J. Pathogenesis of drug-induced exanthema. Int Arch Allergy Immunol 2001, 124(1-3):336-338.
-
(2001)
Int Arch Allergy Immunol
, vol.124
, Issue.1-3
, pp. 336-338
-
-
Yawalkar, N.1
Pichler, W.J.2
-
78
-
-
0034538071
-
Evidence for a role for IL-5 and eotaxin in activating and recruiting eosinophils in drug-induced cutaneous eruptions
-
Yawalkar N., Shrikhande M., Hari Y., et al. Evidence for a role for IL-5 and eotaxin in activating and recruiting eosinophils in drug-induced cutaneous eruptions. JAllergy Clin Immunol 2000, 106(6):1171-1176.
-
(2000)
JAllergy Clin Immunol
, vol.106
, Issue.6
, pp. 1171-1176
-
-
Yawalkar, N.1
Shrikhande, M.2
Hari, Y.3
-
79
-
-
77956122415
-
Drug reaction with eosinophilia and systemic symptoms (DRESS): a multiorgan antiviral T cell response
-
Picard D., Janela B., Descamps V., et al. Drug reaction with eosinophilia and systemic symptoms (DRESS): a multiorgan antiviral T cell response. Sci Transl Med 2010, 2(46):46ra62.
-
(2010)
Sci Transl Med
, vol.2
, Issue.46
-
-
Picard, D.1
Janela, B.2
Descamps, V.3
-
80
-
-
3242752593
-
Characterization of human T cells that regulate neutrophilic skin inflammation
-
Schaerli P., Britschgi M., Keller M., et al. Characterization of human T cells that regulate neutrophilic skin inflammation. JImmunol 2004, 173(3):2151-2158.
-
(2004)
JImmunol
, vol.173
, Issue.3
, pp. 2151-2158
-
-
Schaerli, P.1
Britschgi, M.2
Keller, M.3
-
81
-
-
0034986623
-
T-cell involvement in drug-induced acute generalized exanthematous pustulosis
-
Britschgi M., Steiner U.C., Schmid S., et al. T-cell involvement in drug-induced acute generalized exanthematous pustulosis. JClin Invest 2001, 107(11):1433-1441.
-
(2001)
JClin Invest
, vol.107
, Issue.11
, pp. 1433-1441
-
-
Britschgi, M.1
Steiner, U.C.2
Schmid, S.3
-
82
-
-
84862776700
-
Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome
-
Wei C.Y., Chung W.H., Huang H.W., et al. Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome. JAllergy Clin Immunol 2012, 129(6):1562-1569.e5.
-
(2012)
JAllergy Clin Immunol
, vol.129
, Issue.6
-
-
Wei, C.Y.1
Chung, W.H.2
Huang, H.W.3
-
83
-
-
82555166978
-
Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome
-
Ko T.M., Chung W.H., Wei C.Y., et al. Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome. JAllergy Clin Immunol 2011, 128:1266-1276.e11.
-
(2011)
JAllergy Clin Immunol
, vol.128
-
-
Ko, T.M.1
Chung, W.H.2
Wei, C.Y.3
-
84
-
-
69149097823
-
Fulminant liver failure after vancomycin in a sulfasalazine-induced DRESS syndrome: fatal recurrence after liver transplantation
-
Mennicke M., Zawodniak A., Keller M., et al. Fulminant liver failure after vancomycin in a sulfasalazine-induced DRESS syndrome: fatal recurrence after liver transplantation. Am J Transplant 2009, 9(9):2197-2202.
-
(2009)
Am J Transplant
, vol.9
, Issue.9
, pp. 2197-2202
-
-
Mennicke, M.1
Zawodniak, A.2
Keller, M.3
-
85
-
-
9844252868
-
Diagnostic value of specific T cell reactivity to drugs in 95 cases of drug induced liver injury
-
Maria V.A., Victorino R.M. Diagnostic value of specific T cell reactivity to drugs in 95 cases of drug induced liver injury. Gut 1997, 41(4):534-540.
-
(1997)
Gut
, vol.41
, Issue.4
, pp. 534-540
-
-
Maria, V.A.1
Victorino, R.M.2
|